Hepatitis Weekly articles from July 2004

Hepatitis Weekly archives from July 2004

Severe infections plague acute alcoholic hepatitis patients given infliximab.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Severe infections plague acute alcoholic hepatitis patients given infliximab. According to published research from France, "tumor necrosis factor-alpha (TNF-alpha) may contribute to the progression...

Steatosis exacerbates liver injury in patients with chronic hepatitis C.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Steatosis exacerbates liver injury in patients with chronic hepatitis C. "Steatosis is increasingly recognized as a cofactor influencing the progression of fibrosis in chronic hepatitis C however,...

Insulin resistance helps predict chronic hepatitis C-related liver fibrosis.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Insulin resistance helps predict chronic hepatitis C-related liver fibrosis. According to researchers in Australia, "we sought to develop a clinically useful index comprising standard and...

CD8+ T-cell expansion impedes interferon's efforts against hepatitis C virus.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- CD8+ T-cell expansion impedes interferon's efforts against hepatitis C virus. "The role of CD8+ T lymphocytes in chronic hepatitis C virus (HCV) infection and in liver injury with subsequent...

Intramuscular hepatitis B immunoglobulin offers advantages to liver recipients.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Intramuscular hepatitis B immunoglobulin offers advantages to liver recipients. According to a study from Italy, "the combination of lamivudine and hepatitis B immunoglobulins (HBIg) to prevent...

Zinc controls nuclear factor-kappa B activation to protect against liver injury.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Zinc controls nuclear factor-kappa B activation to protect against liver injury. "Endotoxin (lipopolysaccharide, LPS)-induced tumor necrosis factor-alpha (TNF-alpha) release from Kupffer cells is...

Interventional radiology manages vascular complications after liver transplants.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Interventional radiology manages vascular complications after liver transplants. "The purpose of this study is to review the role of the percutaneous interventional procedures in the treatment of...

Warren Alpert Foundation Prize awarded to interferon therapy researchers.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Sidney Pestka, MD, whose pioneering research made interferon therapy for hepatitis C and other viral diseases a reality, was named with two others as winner of the 16th annual Warren Alpert Foundation...

Isis gains full ownership of Orasense and HepaSense subsidiaries.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Isis Pharmaceuticals, Inc., (ISIS) announced that it has entered into an agreement with a subsidiary of Elan Corp., plc, to acquire Elan's minority interest in Orasense and HepaSense, joint ventures...

Trial results reported in HGS-ETR1 in patients with advanced cancers.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that the results of ongoing phase I clinical trials demonstrate the safety and tolerability of HGS-ETR1 (agonistic human monoclonal antibody to TRAIL...

LPS-binding protein predicts infection in cirrhotic patients.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Serum lipopolysaccharide (LPS)-binding protein levels are predictive of severe bacterial infection in cirrhotic patients with ascites. According to recent research from Spain, "Serum...

Diabetes associated with lichen planus cases in Turkey.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Diabetes was associated with lichen planus cases in the Cukurova region of Turkey. According to recent research published in the Journal of Dermatology, "The aim of the present study was to...

Megamitochondrial artifacts randomize in nonalcoholic steatohepatitis livers.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Megamitochondrial artifacts randomize in nonalcoholic steatohepatitis livers. According to a study from the United States, "megamitochondria with crystalline inclusions (MMC) have been previously...

Wy-14,643 reverses nutritional fibrosis and steatohepatitis in animal models.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Wy-14,643 reverses nutritional fibrosis and steatohepatitis in animal models. According to recent research published in the journal Hepatology, "administration of a methionine and choline deficient...

Management strategy for anemia in HIV infection elucidated.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A management strategy for anemia in HIV infection has been elucidated by consensus. According to a study from the United States, "Anemia in human immunodeficiency virus (HIV)-infected patients can...

Hepatitis E virus in human feces detected and quantitated by real-time PCR.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Hepatitis E virus in human feces was detected and quantitated by a real-time PCR assay. "Hepatitis E virus (HEV) is the causative agent of an acute and self-limited form of hepatitis. The virus is...

Hepatitis C reigns among mental health patients and substance abusers in Japan.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Hepatitis C reigns among mental health patients and substance abusers in Japan. According to recent research from Japan, "the prevalence of anti-hepatitis C virus (HCV) antibody in 1193 hospitalized...

HBV/HIV coinfected patients increased risk for virologic failure after HAART.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- HBV/HIV coinfected patients have an increased risk for virologic failure after HAART. "Between June 1994 and February 2003, a total of 111 human immunodeficiency virus (HIV)-infected patients with...

Hepatitis delta virus ribozymes are controlled by a conformational switch.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Hepatitis delta virus ribozymes are controlled by a conformational switch. "Ribozymes enhance chemical reaction rates using many of the same catalytic strategies as protein enzymes. In the hepatitis...

VA to host free hepatitis C screening for veterans.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- New Jersey and New York veterans have the highest risk for hepatitis C in the nation, so the Veterans Administration and U.S. Representative Rodney Frelinghuysen are sponsoring a free screening for the...

Ribavirin patent infringement case dismissed.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Par Pharmaceutical Companies, Inc., (PRX) announced that the appeal filed by Valeant Pharmaceuticals International, formerly ICN Pharmaceuticals, Inc., has been dismissed at Valeant's request. In...

Interleukin 22 is a liver cell survival factor in murine liver injury models.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Interleukin 22 is a liver cell survival factor in murine liver injury models. According to published research from the United States, "the central role of T cell activation in hepatocellular injury...

The CXCR3 ligand I-TAC correlates with chronic hepatitis C-related inflammation.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- The CXCR3 ligand I-TAC correlates with chronic hepatitis C-related inflammation. According to recent research from Australia, "the factors that regulate lymphocyte traffic in chronic hepatitis C...

Research and development company adds new member to scientific advisory board.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Trillium Therapeutics Inc. (TTI) announced that Marc Feldmann, a professor at Imperial College London and head of the Kennedy Institute of Rheumatology Division, has agreed to join the company's...

Hospital says flawed cleaning procedure may have exposed patients to viruses.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- A hospital notified 177 patients that they may have been exposed to HIV or hepatitis because equipment used to check their digestive systems might not have been properly cleaned. North Shore...

Interferon blocks HCV-induced renal injury after transplantation.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Interferon blocks HCV-induced renal injury after transplantation. "Hepatitis C virus (HCV) infection is the main cause of chronic liver disease after renal transplantation (RT). It is considered in...

Scottish study of deaths in drug injectors shows early help is critical.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Government and health care services are being urged to make special help available for young people who inject drugs, in a bid to minimize drug-related deaths. In a newly published study of causes...

Systemic efficacy of siRNAs demonstrated in multiple animal models.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Sirna Therapeutics, Inc., (RNAI) announced in a presentation at the BIO 2004 Annual International Convention that it has demonstrated reproducible and robust preclinical systemic efficacy using its...

Hepatitis C virus genotype 1a responds to a host of immunodominant epitopes.
July 5, 2004... 2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus genotype 1a responds to a host of immunodominant epitopes. According to recent research published in the journal Clinical Immunology, "cellular immunity against multiple hepatitis...

Chronic hepatitis C patients bear hepatitis B DNA solely in the liver.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Chronic hepatitis C patients bear hepatitis B DNA solely in the liver. "Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B....

Hepatitis C virus core antigen assay confirms viremia in asymptomatic carriers.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core antigen assay confirms viremia in asymptomatic carriers. "Nucleic acid amplification-based methods are used for confirmation of viremia in antibody to hepatitis C virus...

Epoetin alfa might minimize ribavirin-related blood disorders.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Epoetin alfa might minimize ribavirin-related blood disorders. According to a study from the United States, "the current standard of care for the treatment of hepatitis C virus (HCV) infection is...

Select polyunsaturated fatty acids synergize with interferon to hinder HCV RNA.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Select polyunsaturated fatty acids synergize with interferon to hinder HCV RNA. According to recent research from Taiwan, "HCV infection can lead to chronic infectious hepatitis disease with...

Latent hepatitis C virus infection is detected in the central nervous system.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Latent hepatitis C virus infection is detected in the central nervous system. "Reports of cerebral dysfunction in chronic hepatitis C virus (HCV) infection have led to the suggestion that HCV may...

Modifications improve the potency of hepatitis C virus NS3 protease inhibitors.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Modifications improve the potency of hepatitis C virus NS3 protease inhibitors. "The structure-activity relationship at the C-terminal position of peptide-based inhibitors of the hepatitis C virus...

Utility of radiofrequency ablation of liver metastases reviewed.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- The utility of radiofrequency (RF) ablation of liver metastases has been reviewed. "The liver is second only to lymph nodes as the most common site of metastatic disease irrespective of the primary...

Adenovirus encoding HCA661 targets hepatoma cells.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Transduction of dendritic cells with recombinant adenovirus encoding HCA661 activates autologous cytotoxic T lymphocytes to target hepatoma cells. According to recent research from China,...

FDA turns down two requests to resume green onion shipments.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- The Food and Drug Administration (FDA) has turned down two Mexican growers' requests to resume shipping green onions to the United States after they were implicated in last year's hepatitis A outbreak...

IDN-6556 maker completes $27M first closing of a $65.6M private placement.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Idun Pharmaceuticals, Inc., announced the funding of a $27 million preferred stock private placement financing led by MPM Capital, representing the initial tranche of a 2-part financing of $65.6...

Cirrhosis foreshadows liver cancer in nonalcoholic steatohepatitis patients.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Cirrhosis foreshadows liver cancer in nonalcoholic steatohepatitis patients. "Nonalcoholic steatohepatitis (NASH) was originally believed to be a benign disease. However, it has been recently...

Contrast-enhanced ultrasound exposes the hemodynamics of liver cancer lesions.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Contrast-enhanced ultrasound exposes the hemodynamics of liver cancer lesions. "The purpose of this study was to evaluate the detection rate of tumor vessels and vascularity in hepatocellular...

HIV antibody test false-positive in a dialysis patient.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- An HIV antibody test was false-positive in a dialysis patient. According to recent research published in the journal Pediatric Nephrology, "A patient developed end-stage renal disease secondary to...

Journal reports successful use of Multiferon for hepatitis C.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Viragen, Inc., (VRA) announced that an article published in a Scandinavian medical journal concludes that Multiferon provides an effective therapeutic alternative for difficult-to-treat patients with...

Pivotal phase III trial of daily Infergen plus ribavirin begins.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., (ITMN) has initiated the DIRECT Trial, a phase III clinical trial designed to evaluate the safety and efficacy of daily Infergen (Interferon alfacon-1) in combination with ribavirin...

Occupational risk for hepatitis A reviewed.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Researchers review the occupational risk for hepatitis A in a recent issue of the Journal of Clinical Gastroenterology. "Hepatitis A virus is the most frequently occurring vaccine-preventable...

Prevalence of hepatitis A antibodies in Spanish children determined.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Scientists have determined the prevalence of hepatitis A antibodies in schoolchildren in Catalonia, Spain, after the introduction of universal hepatitis A immunization. According to a study from...

Tobacco cells produce antibodies to hepatitis B virus surface antigen.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Transgenic tobacco cells can produce human monoclonal antibodies to hepatitis B virus surface antigen. "The recombinant human monoclonal antibody (MAb) against hepatitis B virus (HBV) surface...

Whole bacteriophage lambda particles protect against hepatitis B.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Whole bacteriophage lambda particles provided genetic immunization against hepatitis B. "Mice and rabbits have been vaccinated with whole bacteriophage lambda particles containing a DNA vaccine...

Surface-antigen-negative hepatitis B virus infection analyzed.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Researchers have conducted a molecular and serological evaluation of surface-antigen-negative hepatitis B virus infection in blood donors from Venezuela. "Surface antigen negative hepatitis B...

The new liver cell line Chang-HBx has limited tumorigenicity.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- The new liver cell line Chang-HBx has limited tumorigenicity. According to published research from Taiwan, "the hepatitis B virus X gene, which encodes the HBx protein, has multiple functions and...

FDA approves study to evaluate non-pharmacological treatment for hepatitis C.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Energex Systems, Inc., announced that it has been granted conditional approval from the U.S. Food and Drug Administration (FDA) to use its experimental, Hemo-Modulator technology in a clinical trial of...

Second phase III study of Viramidine in hepatitis C commences.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Valeant Pharmaceuticals (VRX) has commenced the second of two global phase III clinical trials for its antiviral compound, Viramidine, a nucleoside (guanosine) analog in oral form, for the treatment of...

VX-950 hepatitis C therapy to be developed and commercialized in Japan.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Vertex Pharmaceuticals Incorporated (VRTX) and Mitsubishi Pharma Corporation have signed an agreement to develop and commercialize VX-950, Vertex's investigational oral protease inhibitor for the...

Immunization with hepatitis C core gene triggers T-cell response.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Immunization with hepatitis C virus core gene triggers potent T-cell response, but affects CD4+T-cells. "Numerous attempts to induce immunity against HCV core (HCV-C) by DNA immunization met...

The novel non-A, non-E hepatitis viruses may be commensal or pathogenic.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- The novel non-A, non-E hepatitis viruses may be commensal viruses or pathogenic. "Molecular techniques have allowed the identification of new viruses in a number of patients with cryptogenic...

Tumor necrosis may enable liver cancer patients to wait longer for transplants.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Tumor necrosis may enable liver cancer patients to wait longer for transplants. According to recent research from the United States, "although liver transplantation (LT) is likely the most...

The kava alkaloid pipermethystine produces death in liver cells.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- The kava alkaloid pipermethystine produces death in liver cells. "Kava herbal supplements have been recently associated with acute hepatotoxicity, leading to the ban of kava products in...

Soluble Fas and its ligand associate with hepatitis B virus-related progression.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Soluble Fas and its ligand associate with hepatitis B virus-related progression. "Earlier studies of both chronic hepatitis B and C virus (HBV and HCV) patients have shown a strong correlation...

Anticonvulsant hypersensitivity syndrome case linked to alternative therapy.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Dermatologists with Brigham & Women's Hospital reported on a case of anticonvulsant hypersensitivity syndrome that developed in a woman taking Bellamine S for hot flashes. "Anticonvulsant...

Hepatitis B virus X protein upregulates human S15a expression.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein upregulates human S15a expression. "The hepatitis B virus (HBV)-encoded X antigen (HBxAg) may contribute to the development of hepatocellular carcinoma (HCC) through...

Hepatitis C virus-infected adolescents in Taiwan exhibit low chronicity.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus-infected adolescents in Taiwan exhibit low chronicity. According to recent research published in the journal Transactions of the Royal Society of Tropical Medicine and Hygiene,...

Antivirals and steroids are indicated for HBV-related polyarteritis nodosa.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Antivirals and steroids are indicated for HBV-related polyarteritis nodosa. According to recent research from Belgium, "a substantial number of cases of polyarteritis nodosa (PAN) are related to...

Overexpressed p53 is involved in the pathogenesis of fatty liver disease.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Overexpressed p53 is involved in the pathogenesis of fatty liver disease. "Obesity is a major health problem in industrialized societies, and fatty liver disease (hepatic steatosis) is common in...

Hepadnavirus L proteins contain separate domains that impact infectivity.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Hepadnavirus L proteins contain separate domains that impact infectivity. According to a study from the United States, "hepatitis B virus (HBV) and woolly monkey hepatitis B virus (WMHBV) have...

Hepadnaviruses have differential translocation mechanisms.
July 12, 2004... 2004 JUL 12 - (NewsRx.com & NewsRx.net) -- Hepadnaviruses have differential translocation mechanisms. "For functional diversity, the large (L) envelope protein of hepatitis B virus (HBV) acquires a dual transmembrane topology via...

The high affinity phage PHH2 will improve hepatitis B virus screening.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- The high affinity phage PHH2 will improve hepatitis B virus screening. "An M13 phage, called PHH2, with the ability to bind hepatitis B surface antigen (HBsAg) was isolated from a coat protein III...

RNA extraction via oligo cellulose simplifies hepatitis A virus detection.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- RNA extraction via oligo cellulose simplifies hepatitis A virus detection. According to recent research from Italy, "the hepatitis A virus (HAV) is the most common cause of viral infection linked...

Hepatitis C virus type 2a subgenomic replicons thrive in human liver cells.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus type 2a subgenomic replicons thrive in human liver cells. "A hepatitis C virus genotype 2a subgenomic replicon, JFH-1 replicon, was previously established using the consensus...

Genetic profiles of liver cirrhosis nodules disclose valuable information.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Genetic profiles of liver cirrhosis nodules disclose valuable information. According to published research from Japan, "to disclose genetic mechanisms involved in development or progression of...

Hepatitis C virus infection associates with the risk for Hodgkin disease.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus infection associates with the risk for Hodgkin disease. "Hepatitis C virus (HCV) has been associated with non-Hodgkin lymphoma (NHL), but the evidence from case series and...

Utility of radiofrequency ablation of liver metastases reviewed.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- The utility of radiofrequency (RF) ablation of liver metastases has been reviewed. "The liver is second only to lymph nodes as the most common site of metastatic disease irrespective of the primary...

The weight loss supplement usnic acid may lead to liver failure.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- The weight loss supplement usnic acid may lead to liver failure. "The use of complementary and alternative medicine (CAM) in developed countries has increased significantly over the years. Among...

Polyacrylonitrile-based ultrafiltration membranes retain hepatitis A virus.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Polyacrylonitrile-based ultrafiltration membranes retain hepatitis A virus. According to a study from India, "ultrafiltration-based polyacrylonitrile membranes (UF-membranes) were evaluated for...

Methadone plus HAART can be implemented with good results in HIV-infection.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Methadone plus HAART can be implemented with good results in HIV-infection. According to a study from Canada, "The objective of this prospective, observational clinical study was to evaluate the...

Company releases multilanguage hepatitis B educational materials.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) announced the release of new educational materials that address the causes, symptoms, and risks associated with chronic hepatitis B. The video, "Hepatitis B: Facing the...

von Willebrand factor-binding protein isolated from Staphylococcus.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Scientists have isolated a von Willebrand factor-binding protein from Staphylococcus lugdunensis. "In the present study, a phage display library covering the genome of Staphylococcus lugdunensis,...

There is no link between p53 codon 72 polymorphism and liver disease severity.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- There is no link between p53 codon 72 polymorphism and liver disease severity. "Chronic hepatitis C virus (HCV) infection is the most frequent cause of progressive liver disease and liver cancer in...

Phase II/III hepatitis B trial initiated.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Dynavax Technologies Corporation (DVAX), a biopharmaceutical company focused on the discovery, development, and commercialization of innovative products to treat and prevent allergies, infectious...

Nonexclusive HCV license granted to Prosetta.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced that it has granted a nonexclusive license to Prosetta Corporation for the research, development and commercialization of therapeutics against certain hepatitis C...

No evidence of sexual transmission of HCV among monogamous couples.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Heterosexual monogamous couples do not risk sexual transmission of hepatitis C virus (HCV), research from Italy indicates. "The risk of sexual transmission of hepatitis C virus (HCV) infection was...

Viral hepatitis transmission in ambulatory health settings reviewed.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Researchers review viral hepatitis transmission in ambulatory health care settings in a recent issue of Clinical Infectious Diseases. "In the United States, transmission of viral hepatitis from...

Novel class of phosphonate nucleosides potent and selective anti-HBV agent.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- A novel class of phosphonate nucleosides is a potent and selective anti-HBV agent. "9-[1-(Phosphonomethoxycyclopropyl)methyl]guanine (PMCG, 1), representative of a novel class of phosphonate...

Plasma tests for Ser-249 TP53 mutations disclose liver cancer status.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Plasma tests for Ser-249 TP53 mutations disclose liver cancer status. "Hepatocellular carcinoma (HCC) is frequent in areas of high exposure to aflatoxin and high prevalence of HBV infection, such...

Antiviral cytokines induce granzyme B inhibitor/PI-9/SPI-6 hepatic expression.
July 19, 2004... 2004 JUL 19 - (NewsRx.com & NewsRx.net) -- Antiviral cytokines induce granzyme B inhibitor/PI-9/SPI-6 hepatic expression. "Expression of the granzyme B inhibitors, human proteinase inhibitor 9 (PI-9), or the murine orthologue, serine...