Hepatitis Weekly articles from January 2004

Hepatitis Weekly archives from January 2004

Shock is an underlying factor in hypoxic hepatitis only half of the time.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Shock is an underlying factor in hypoxic hepatitis only half of the time. According to a study from Belgium, "the centrilobular liver cell necrosis observed in hypoxic hepatitis is generally...

Vascular and thrombotic complications compromise living donor liver grafts.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Vascular and thrombotic complications compromise living donor liver grafts. According to recent research from the United States, "live donor adult liver transplantation (LDALT) utilizing right-lobe...

Patient and viral factors correlate with pediatric response to lamivudine.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Patient and viral factors correlate with pediatric response to lamivudine. "Despite the recent approval of lamivudine for the treatment of children with chronic hepatitis B virus (HBV) infection,...

Zinc and antioxidants limit the injury some xenobotics may cause the liver.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Zinc and antioxidants limit the injury some xenobotics may cause the liver. According to recent research published in the journal Experimental and Molecular Pathology, "hepatic metabolism of...

Transgastric fine-needle biopsies sample high risk patients for malignancy.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Transgastric fine-needle biopsies sample high risk patients for malignancy. "Hepatocellular carcinoma (HCC) is the most common primary malignancy arising within the liver and most often affects...

Short hairpin RNAs inhibit hepatitis B virus replication.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Short hairpin RNAs inhibit hepatitis B virus replication. "The major challenges for anti-hepatitis B Virus (HBV) therapy are the low efficacy of current drugs and the occurrence of drug resistant...

Food allergies may be treatable with immunotherapy, anti-IgE antibodies, herbs.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Treatments that may work against food allergy include immunotherapy, anti- immunoglobulin E (IgE) antibody therapy, and Chinese herbs. "Up to 5% of young children and 2% of adults suffer from food...

A new heterocyclic HCV replicon RNA synthesis inhibitor has distinct kinetics.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A new heterocyclic HCV replicon RNA synthesis inhibitor has distinct kinetics. "Recently, a benzo-1,2,4-thiadiazine was shown to be a potent, specific inhibitor of the hepatitis C virus (HCV) RNA...

National Blood Service in England begins nucleic acid testing.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced that the National Blood Service in England has begun nucleic acid testing (NAT) at its Brentwood site with the company's Procleix HIV-1/HCV Assay. The assay is...

Organosulfer compounds stop liver cancer invasion, migration, and angiogenesis.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Organosulfer compounds stop liver cancer invasion, migration, and angiogenesis. According to a study from South Korea, "numerous studies have revealed the chemopreventive and hepatoprotective...

Impaired interleukin-15 production impedes the effectiveness of interferon.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Impaired interleukin-15 production impedes the effectiveness of interferon. "We previously reported that monocyte-derived dendritic cells activate resting natural killer (NK) cells by expressing...

The antifungal ketoconazole may cause liver injury.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The antifungal ketoconazole may cause liver injury. "We describe a previously healthy woman who developed liver cirrhosis as a sequela of acute hepatic injury that was induced by ketoconazole...

The Chemagic viral DNA/RNA kit improves viral extraction.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The Chemagic viral DNA/RNA kit improves viral extraction. "The Chemagic viral DNA/RNA kit was evaluated for extraction of cytomegalovirus (CMV), hepatitis B virus (HBV), and hepatitis G virus (HGV)...

Advanced and refractory human alveolar echinococcosis responds to amphotericin B.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Advanced and refractory human alveolar echinococcosis responds to amphotericin B; parasite growth is controlled. According to recent research from Germany, "most patients with alveolar...

Intravenous immunoglobulin may resolve acquired factor V inhibitor complications.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Intravenous immunoglobulin may resolve acquired factor V (FV)inhibitor complications; antibiotics could be one cause. "We report two patients who developed acquired... FV inhibitors not related to...

Lentiviral vectors efficiently transduce HLECs.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Lentiviral vectors can efficiently deliver therapeutic genes to cultured HLECs. "Endothelial cells play multiple roles in pathophysiologic processes and are increasingly being recognized as target...

Clinical trials begin for Procleix Ultrio assay.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) and Gen-Probe Incorporated (GPRO) announced that clinical trials of the Procleix Ultrio Assay, for the simultaneous detection of HIV-1, hepatitis C virus (HCV) and hepatitis B...

A key hepatitis C virus protein modulates apoptosis in liver cells.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A key hepatitis C virus protein modulates apoptosis in liver cells. "To analyze the influence of hepatitis C virus nonstructural protein 5A (NS5A) on apoptosis, we established Huh7 cells that stably...

Hepatitis A vaccine does not promote atherogenesis in murine model.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The hepatitis A vaccine did not promote atherogenesis in a murine model. According to recent research from the United States, "Our laboratory demonstrated that seropositivity to hepatitis A virus...

AIDS therapy less risky than assumed.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The immune deficiency syndrome AIDS can by now be treated successfully with effective drug cocktails. Unfortunately, however, these involve the risk of dangerous side effects, as the drugs employed in...

Company announces positive test results for A4+L.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Organetix, Inc., (OGTX) announced that previous testing of Organetix's A4+L has demonstrated positive results in treating patients suffering from hepatitis C. Dr. Jose Cabanillas along with two...

Liver biopsies provide clues for the management of liver diseases.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Liver biopsies provide clues for the management of liver diseases. According to recent research published in the Canadian Journal of Gastroenterology, "the role of liver biopsy in the diagnosis and...

Use of corticosteroids, cyclosporine may stop GVHD in some human SCID patients.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Use of corticosteroids and cyclosporine may stop GVHD in some human severe combined immunodeficient (SCID) patients. "An X-linked severe combined immunodeficient (SCID) patient received a...

Non-organ-specific autoantibodies prevail in nonalcoholic fatty liver disease.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Non-organ-specific autoantibodies prevail in nonalcoholic fatty liver disease. "Eighty-four consecutive subjects with nonalcoholic fatty liver disease (NAFLD) were tested for non-organ-specific...

Virological responders to hepatitis C virus therapy have more CD8+ cells.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Virological responders to hepatitis C virus therapy have more CD8+ cells. According to researchers in the Netherlands, "we analyzed the relationship between virological response and baseline immune...

Interferon-gamma is lower in HCV-positive patients with liver fibrosis.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Interferon-gamma is lower in HCV-positive patients with liver fibrosis. "Liver fibrosis was correlated with immunological parameters. Peripheral blood mononuclear cells (PBMCs) from patients with...

David Arkowitz becomes CFO.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Idenix Pharmaceuticals, Inc., announced the appointment of David Arkowitz to the position of CFO. Arkowitz has more than 13 years of experience in financial leadership positions at Merck & Co,...

Refractory Rasmussen syndrome may be treatable by thalidomide.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Refractory Rasmussen syndrome may be treatable by thalidomide. According to recent research published in the journal Pediatric Neurology, "we report a 13-year-old female who experienced symptoms...

Mannose-binding lectin polymorphisms are linked to sepsis, related mortality.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Mannose-binding lectin (MBL) polymorphisms providing for lower expression are linked to sepsis, related mortality. According to a study from Denmark, "genetic factors may predispose critically ill...

Pharmaceutical and USAMRIID collaborate on molecule-screening program.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Kemin Pharma announced the formation of a collaborative molecule-screening program with the U.S. Army Medical Research Institute for Infectious Diseases (USAMRIID). Under the terms of the...

Kidney recipients with high pretransplant CD30 benefit most from HLA matching.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- If kidney transplant patients have high pretransplant CD30, they will benefit most from a good human leukocyte antigen (HLA) match. "The influence of HLA matching on graft survival is greater in...

Effects of GBV-C co-infection on HIV progression reviewed.
January 5, 2004... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The effects of GB virus type C hepatitis G virus (GBV-C) co-infection on HIV progression have been reviewed. GBV-C "is a common virus that does not appear to cause disease," scientists in the...

Consolidation therapy improves sustained response in HCV genotype 1b patients.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Consolidation therapy improves sustained response in HCV genotype 1b patients. According to a study from Italy, "this randomized controlled study involved 236 1b genotype (121 males) naive patients...

Rodents with inducible suicide genes will advance liver disease drug research.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Rodents with inducible suicide genes will advance liver disease drug research. According to published research from Japan, "suicide gene expression in specific tissue of transgenic animals has been...

Hepatitis C and Schistosoma mansoni coinfections cause T-cell depletion.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Hepatitis C and Schistosoma mansoni coinfections cause T-cell depletion. According to a study from the United States, "factors that influence the generation and maintenance of memory CD8(+) T cells...

Hepatitis C virus infection may encourage the formation of diabetic amyotrophy.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus infection may encourage the formation of diabetic amyotrophy. "The objective of this study was to present a case of diabetic amyotrophy (DA) associated with hepatitis C virus...

Response to hepatitis C virus therapy can be predicted within 4 weeks.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Response to hepatitis C virus therapy can be predicted within 4 weeks. "The prognostic value of early hepatitis C virus (HCV)-RNA load was evaluated among nonresponder patients to previous...

Liver transplant patients with renal dysfunction from CNI may improve with MMF.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Pediatric liver transplant patients with renal dysfunction from CNI may improve with mycophenolate mofetil therapy. According to recent research from Italy, "the prolonged use of CNI has been...

Primary biliary cirrhosis research at Mount Sinai advances due to trust, trials.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Primary biliary cirrhosis research at Mount Sinai advances due to trust money, clinical trials. According to published research from the United States, "individuals afflicted with primary biliary...

Blood sterility testing must be from a bag location that avoids false positivity.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- The location of testing for sterility in blood bags while investigating adverse transfusion reactions matters; false positives are possible from patient blood reflux. "We report on the case of a...

Non-obligate chain-terminating ribonucleoside analogs inhibit HCV replication.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Non-obligate chain-terminating ribonucleoside analogs inhibit HCV replication. "The urgent need for efficacious drugs to treat chronic hepatitis C virus (HCV) infection requires a concerted effort...

TIPS improves cardiac function in hypovolemic patients.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- TIPS improves cardiac function in hypovolemic cirrhosis patients. Scientists in Italy conducted a study "to evaluate the cardiac effects of transjugular intrahepatic porto-systemic shunts (TIPS) in...

Nonexclusive HCV license granted to Boehringer Ingelheim.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced that it has granted to Boehringer Ingelheim International GmbH a nonexclusive license for the research, development, and commercialization of small molecule...

Drug discovery company announces 2003 net loss of $3,925,000.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Incara Pharmaceuticals Corp. (ICRA) announced financial results for its fiscal year ended September 30, 2003. The company reported a net loss attributable to common stockholders of $3,925,000, or...

Gene identification company reports 73.7% gross profit margin.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Enzo Biochem, Inc., (ENZ), a biotechnology company specializing in gene identification and genetic and immune regulation technologies for diagnostic and therapeutic applications, reported operating...

TNF-alpha may play an early role in the malignant transformation of liver cells.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- TNF-alpha may play an early role in the malignant transformation of liver cells. "Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, usually arising from a background of...

Hepatitis B treatment for HIV patients reviewed.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Current and future options for hepatitis B treatment in HIV patients have been reviewed. "The management of chronic hepatitis B poses specific problems in the presence of human immunodeficiency...

Neuroprotection due to HSP induction may occur with geranylgeranylacetone.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Neuroprotective effects due to heat shock protein induction are possible with oral of geranylgeranylacetone in an animal model. "Geranylgeranylacetone (GGA), more commonly known as an antiulcer...

No further cases reported in Pennsylvania outbreak.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- For the first time since state officials discovered a hepatitis A outbreak linked to tainted green onions served at a Mexican restaurant in western Pennsylvania nearly 2 months ago, the state health...

Chimeric antibodies target hepatitis B virus pre-S2 surface antigen.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Chimeric antibodies target hepatitis B virus pre-S2 surface antigen. According to researchers in South Korea, "we have constructed a humanized antibody with specificity for the pre-S2 surface...

Data reported from phase IB trial of Isatoribine.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Anadys Pharmaceuticals, Inc., at the HEP DART 2003 Meeting on Frontiers in Drug Development for Viral Hepatitis in Kauai, Hawaii, reported interim results from an ongoing clinical trial of isatoribine...

Investigational drug, merimepodib, well tolerated in hepatitis C clinical trial.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- An investigational new drug, merimepodib (VX-497), enhances the antiviral effect of pegylated-interferon (peg-IFN) and ribavirin at 24 weeks of treatment in hepatitis C virus (HCV) patients who were...

Biotechnology company increases production capacity of liver treatment.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Organetix, Inc., (OGTX) has begun increasing its manufacturing capability for the A4+L liver product. Brad Clarke, president and chief executive officer of Organetix stated, "We are pleased with...

Interim findings reported on Infergen plus Actimmune combination therapy.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., (ITMN) announced the presentation of interim findings from an independent retrospective clinical analysis done in collaboration with the New Jersey Medical Liver Center evaluating the...

Hepatitis C virus in tissue samples helps identify mixed up patient specimens.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus in tissue samples helps identify mixed up patient specimens. "Despite advances in medical technology, careful specimen identification is still a fundamental principle of...

The combination of high serum albumin, fibrinogen, Ig may pose a thrombotic risk.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Immunoglobulin therapy may only pose a risk of thrombosis if there are high levels of fibrinogen, albumin, and immunoglobin (Ig), but not if any is lower. "Therapeutic administration of Ig has the...

Pharmaceutical company files registration statement for proposed IPO.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Idenix Pharmaceuticals, Inc., announced in December 2003 that it has filed a registration statement with the U.S. Securities and Exchange Commission relating to the proposed initial public offering of...

Acute kidney rejection is lower with basiliximab, independent of cyclosporine.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Acute kidney allograft rejection is low with anti-IL2 basiliximab therapy; cyclosporine dose does not appear to change outcome. According to recent research from Canada, "early adequate...

Aflatoxin B-1 and hepatitis B virus synergize to encourage hepatocarcinogenesis.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Aflatoxin B-1 and hepatitis B virus synergize to encourage hepatocarcinogenesis. According to a study from South Africa, "chronic hepatitis B virus (HBV) infection and dietary exposure to aflatoxin...

Liver cells that encode for HCRP1 avoid hepatocellular carcinoma.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Liver cells that encode for HCRP1 avoid hepatocellular carcinoma. "One of the most frequent allelic deletions in hepatocellular carcinoma (HCC) has been found at chromosome 8p21-23. We reported...

Murine models of human liver cancer exemplify malignant mechanisms.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Murine models of human liver cancer exemplify malignant mechanisms. "Each of the risk factors for human liver cancer (aflatoxin exposure, hepatitis B virus-associated liver injury, p53 loss,...

Chemoembolization improves survival for many with unresectable liver cancer.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Chemoembolization improves survival for many with unresectable liver cancer. According to recent research from Spain, "hepatocellular carcinoma (HCC) is the fifth most common cause of cancer, and...

Desflurane general anesthesia alters hepatic venous pressure.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Desflurane general anesthesia alters hepatic venous pressure. According to recent research from the United States, "physicians perform hepatic venous pressure measurements to guide medical therapy...

Renal function improves in pediatric liver transplant by switch in monitoring.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- In pediatric as well as adult liver transplant recipients, switching to 2-hr cyclosporine post-dose monitoring improves renal function. According to recent research from Israel, "in adult liver...

Hepatitis C virus core protein upregulates TGF-beta[subscript]1 transcription.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein upregulates TGF-beta[subscript]1 transcription. "The majority of persons with chronic hepatitis C virus (HCV) infection develop liver fibrosis. Transforming growth...

A new line probe assay identifies hepatitis B virus precore variants in sera.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- A new line probe assay identifies hepatitis B virus precore variants in sera. According to published research from England, "a prototype line probe assay (LiPA) for identifying hepatitis B virus...

Alpha-actinin may be essential for hepatitis C virus replication.
January 12, 2004... 2004 JAN 12 - (NewsRx.com & NewsRx.net) -- Alpha-actinin may be essential for hepatitis C virus replication. "It has been suggested that cellular proteins are involved in hepatitis C virus (HCV) RNA replication. By using the yeast...

Bilirubin is a simple marker for alcoholic hepatitis treatment response.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Bilirubin is a simple marker for alcoholic hepatitis treatment response. "Early identification of patients with severe (discriminant function greater than or equal to32) biopsy-proven alcoholic...

Estrogen exposure may confer protection against liver cancer.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Estrogen exposure may confer protection against liver cancer. According to recent research from Taiwan, "hepatocellular carcinoma (HCC) is more prevalent in men than in women. Estrogen may play...

Adefovir dipivoxil elicits a response in HBV-positive liver graft recipients.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Adefovir dipivoxil elicits a response in HBV-positive liver graft recipients. According to a study from the United States, "three-hundred and twenty-four patients were enrolled in an open-label,...

Regulatory T cells play a role in hepatitis C virus persistence.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Regulatory T cells play a role in hepatitis C virus persistence. "Hepatitis C virus (HCV) has a high propensity for persistence. To better define the immunologic determinants of HCV clearance and...

Multimodal therapy works well for treating caudate hepatocellular carcinoma.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Multimodal therapy works well for treating caudate hepatocellular carcinoma. According to a study from Japan, "the prognosis of hepatocellular carcinoma originating from the caudate lobe (caudate...

Common antivirals can't totally block hepatitis B virus infection.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Common antivirals can't totally block hepatitis B virus infection. "Adefovir dipivoxil and lamivudine are two safe and efficacious drugs licensed for the treatment of chronic hepatitis B virus...

RNA aptamers can bind and inhibit CTLA-4, increasing antitumor activity.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Multivalent RNA aptamers bind and inhibit CTLA-4, increasing antitumor activity. "The potency of cancer immunotherapy can be enhanced by administration of high-avidity ligands specific to receptors...

Hepatic reserve marks survival in those with HCV-related liver cancer.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Hepatic reserve marks survival in those with HCV-related liver cancer. "To clarify the cumulative recurrence-free interval and survival rate with hepatitis C virus (HCV)-related single, small...

Sepsis heightens mortality after retransplantation for recurrent HCV infection.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Sepsis heightens mortality after retransplantation for recurrent HCV infection. "Retransplantation for recurrent hepatitis C virus (HCV) has been evaluated in small series. In this study, patients...

SPECT asialoglycoprotein receptor dynamics reveal hepatitis status.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- SPECT asialoglycoprotein receptor dynamics reveal hepatitis status. According to published research from Japan, "the asialoglycoprotein receptor (ASGPR) is abundantly expressed on the sinusoidal...

Carbon monoxide combines with nitric oxide to protect liver cells.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Carbon monoxide combines with nitric oxide to protect liver cells. According to published research from the United States, "carbon monoxide (CO) and nitric oxide (NO) each have mechanistically...

HIV coinfection does not alter efficacy of hepatitis C treatment.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Coinfection with HIV does not significantly alter treatment responses in hepatitis C patients. In a recent study, scientists in the United States examined HCV and HIV dynamics "in 10 coinfected...

Elevated cobalamin levels may indicate severe liver disease.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Elevated cobalamin levels may indicate severe liver disease. "Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic...

Immunity persists 4 years after hepatitis B vaccination.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Immunity and seroprotection persist four years after a primary vaccination schedule with a Hansenula polymorpha recombinant hepatitis B vaccine. "To evaluate the persistence of the immune response...

Rates on the decline in the United States but not among adults.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Hepatitis B infections have declined by two-thirds in the United States in the past decade, reflecting the routine use of childhood vaccinations against the liver-attacking virus, U.S. health officials...

Study will compare two antivirals for lamivudine-resistant disease.
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus (HBV) infection that lasts for a long time is an important cause of death, occurrence of disease, and a source of potential new infections around the world. Treatment with nucleoside...

Persistently abnormal liver function tests: Marker of liver disease?
January 19, 2004... 2004 JAN 19 - (NewsRx.com & NewsRx.net) -- Patients with persistently abnormal liver function tests but no serologic evidence of liver disease may nevertheless have hepatitis C virus (HCV) infection, according to a new study. Such occult...