Hepatitis Weekly articles from February 2004

Hepatitis Weekly archives from February 2004

Lamivudine prevents rituximab-induced hepatitis B virus reactivation.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Lamivudine prevents rituximab-induced hepatitis B virus reactivation. According to researchers in Japan, "we used regimens containing rituximab in the treatment of five hepatitis B virus surface...

Erythropoietin amends therapy-induced anemia in patients with hepatitis C.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Erythropoietin amends therapy-induced anemia in patients with hepatitis C. "We are presenting 20 patients with hepatitis C, who developed anemia on interferon alpha-2b/ribavirin treatment and were...

Age and liver status connect hepatitis C virus infection with type 2 diabetes.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Age and liver status connect hepatitis C virus infection with type 2 diabetes. "Past studies of the relation between hepatitis C virus (HCV) infection and type 2 diabetes conflict. The authors aimed...

Hepatic steatosis compromises microcirculation in the liver.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Hepatic steatosis compromises microcirculation in the liver. According to recent research from England, "fatty liver or hepatic steatosis, which is the result of the abnormal accumulation of...

Hepatitis B virus DNA fluctuations mark cell injury and cancer potential.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus DNA fluctuations mark cell injury and cancer potential. "Chronic hepatitis B virus (HBV) carriers with high-titer viremia (>10[superscript]5 virions/ml) are at increased risk for...

Ammoniation removes aflatoxin B-1 from contaminated rice.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Ammoniation removes aflatoxin B-1 from contaminated rice. "Rice, a cereal widely used in Venezuela for human and animal nutrition, is susceptible to aflatoxin contamination in the field and during...

Steatohepatitis and excessive weight-gain complicate risperidone therapy.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Steatohepatitis and excessive weight-gain complicate risperidone therapy. "We report on a 17-year-old girl who developed steatohepatitis and marked weight gain during risperidone treatment for...

First case of ITG in HIV patient without hepatitis reported.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A unique case of ITG in an HIV patient without hepatitis has been reported. Nephrologists in Pennsylvania described "the first case of immunotactoid glomerulopathy (ITG) in a human immunodeficiency...

Liver cancer rates parallel the aging of thalassemic populations in Italy.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Liver cancer rates parallel the aging of thalassemic populations in Italy. According to a study from Italy, "hepatocellular carcinoma (HCC) frequently complicates hepatic cirrhosis secondary to...

Hepatitis B virus X protein does not impair nucleotide excision repair.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein does not impair nucleotide excision repair. According to recent research from South Africa, "the X protein (HBx) of hepatitis B virus (HBV) is thought to compromise...

Proline 495 could be targeted by small-molecule inhibitors of HCV polymerase.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Proline 495 could be targeted by small-molecule inhibitors of HCV polymerase. "The RNA-dependent RNA polymerase of hepatitis C virus (HCV) is the catalytic subunit of the viral RNA amplification...

FDA approves Pegasys prefilled syringes.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Roche announced that the U.S. Food and Drug Administration (FDA) has approved prefilled syringes of Pegasys (Peginterferon alfa-2a) for the treatment of chronic hepatitis C. Pegasys, a pegylated...

Hepatitis C glycoprotein expression leads to cryptic intron excision.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Expression of unmodified hepatitis C virus envelope glycoprotein-coding sequences leads to cryptic intron excision and cell surface expression of E1/E2 heterodimers comprising full-length and partially...

Entangled signals define the nature of cytotoxic T cell-linked liver injury.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Entangled signals define the nature of cytotoxic T cell-linked liver injury. "To understand the role of cytotoxic T cells in liver damage and viral control, we used human histocompatibility...

The pathophysiology of autoimmune hepatitis involves complex mechanisms.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The pathophysiology of autoimmune hepatitis involves complex mechanisms. According to a study from Mexico, "autoimmune hepatitis (AIH) is an inflammatory disease of unknown cause characterized by...

HFE gene mutations associate with fibrosis in chronic hepatitis C patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- HFE gene mutations associate with fibrosis in chronic hepatitis C patients. "Mild iron overload in chronic hepatitis C is associated with liver fibrosis, hepatitis C virus (HCV) genotype 1b...

Hepatitis A virus is a major cause of fulminant hepatitis in Turkish youth.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Hepatitis A virus is a major cause of fulminant hepatitis in Turkish youth. "Fulminant hepatic failure is a rare and devastating event during childhood. The etiology of liver failure is reported to...

Inhibition of SARS coronavirus with Neugene antisense drugs reported.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- AVI BioPharma, Inc., (AVII) presented confirmatory positive results on the inhibition of the SARS coronavirus using its Neugene antisense drugs. Michael Buchmeier, PhD, of The Scripps Research...

Hepatitis C virus core protein uses NF-kappaB to transactivate a key enzyme.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein uses NF-kappa B to transactivate a key enzyme. According to a study from Spain, "intrahepatic levels of the inducible nitric oxide synthase (iNOS) are increased in...

Factors affecting GB virus viability identified.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A number of factors affecting GBV-C viability have been identified. "GB virus C/hepatitis G virus (GBV-C) replication in vitro is inefficient and inconsistent," virologists in the United States...

Longer interferon regimens might clear hepatitis D virus.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Longer interferon regimens might clear hepatitis D virus. According to published research from Turkey, "chronic hepatitis B virus (HBV) infection is a common infectious disease in the world. Two...

Interferon-gamma-inducible protein 10 denotes HCV-linked liver status.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Interferon-gamma-inducible protein 10 denotes HCV-linked liver status. According to published research from Australia, "the factors influencing lymphocyte trafficking to the liver lobule during...

The INNO-LiPA HBV identifies mixed genotypes in difficult samples.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The INNO-LiPA HBV identifies mixed genotypes in difficult samples. "Specific genotypes of hepatitis B virus (HBV) are increasingly recognized for their clinical significance and association with...

Alcohol has a dose-dependent effect on endothelial adhesion molecules.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Alcohol has a dose-dependent effect on endothelial adhesion molecules. "Endothelial adhesion molecules (AM) play an important role in the pathogenesis of several diseases namely infections,...

Endocrine factors underlie bone disease in cirrhotic men and women.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Endocrine factors underlie bone disease in cirrhotic men and women. According to researchers in Australia, "this study aimed to assess the clinical, biochemical and hormonal factors contributing to...

Lamivudine prevents HBV flare in leukemia patients treated with campath-1H.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Lamivudine prevents HBV flare in leukemia patients treated with campath-1H. According to recent research from Germany, "campath-1H, a monoclonal antibody against human CD52, is used for the therapy...

Hepatitis B virus X protein is involved in the etiology of liver cancer.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein is involved in the etiology of liver cancer. According to recent research from Taiwan, "hepatitis B virus X protein (HBx) expressed in Escherichia coli DH5alpha by...

Metabasis joins forces to develop hepatitis C therapeutic.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Metabasis Therapeutics, Inc., and Merck & Co., Inc., (MRK) announced that they have formed a collaboration to research, develop, and commercialize novel small molecule therapeutics for the treatment of...

Hepatitis delta antigens cause varied immunity in mice.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- DNA vaccines consisting of large and small hepatitis delta antigens cause varied immunity in mice. "Whether the hepatitis delta virus (HDV) DNA vaccine can induce anti-HDV antibodies has been...

Hepatitis B virus pre-S mutants flourish in countries with HBV endemicity.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus pre-S mutant rates flourish in countries with HBV endemicity. According to a study from Japan, "it has been reported that hepatitis B virus (HBV) mutants carrying mutations in the...

The etiology of liver steatosis is often virus-related.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The etiology of liver steatosis is often virus-related. According to a study from Portugal, "the mechanism by which the hepatitis C virus (HCV) causes chronic, progressive liver damage is unknown....

Genomic-marker company completes $5.4 million series A financing.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Exagen Diagnostics, Inc., an emerging company in the discovery and development of practical prognostic genomic markers for serious diseases, announced the closing of its series A financing, which raised...

Liver transplantation feasible in HIV/HCV-coinfected patients.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Liver transplantation can be feasible for patients infected with both HIV and hepatitis C virus (HCV). "The prognosis of HIV infection has been modified by antiretroviral therapy," scientists in...

Two-dose hepatitis A vaccine effective in Thai children.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A two-dose hepatitis A vaccine regimen is effective in Thai children. "As fewer children in Thailand are exposed to hepatitis A virus (HAV) and so do not have seroprotective anti-HAV antibodies,...

CHO cell clones expressing hepatitis B surface protein screened.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Scientists have developed a screening method for Chinese hamster ovary (CHO) cell clones expressing histidine-tagged major S hepatitis B surface protein using a semi-quantitative PCR protocol. ...

Hepatitis B infection appears to trigger adult-onset Still disease.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Hepatitis B infection appears to trigger adult-onset Still disease. "Adult-onset Still disease (AOSD) is an uncommon systemic inflammatory disorder that is characterized by quotidian fever,...

Preliminary testing of hepatitis B test kit meets expectations.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Medical Services International, Inc., (MSITF) announced that the preliminary testing of its VScan Hepatitis B rapid test kit had an accuracy of 100% in less than 20 minutes. Standard testing for...

Hepatitis vaccine collaboration signed.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced a new collaboration agreement with CSL Limited, an Australian-based pharmaceutical company, to develop a therapeutic hepatitis C vaccine. Under the terms of the...

Phase I trials of Actilon initiated.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Coley Pharmaceutical Group, Inc., announced the initiation of phase I clinical studies of Actilon (CPG 10101), a novel synthetic TLR9 agonist, targeted for patients with chronic hepatitis C infection...

Company announces development of two new molecules to battle virus.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Kemin Pharma has identified two different molecules that appear to have very good biological effects against the hepatitis C virus (HCV). The first of these molecules is already being tested in...

HEV-neutralizing antibodies recognize antigen of ORF2 protein vaccine.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Monoclonal antibodies that neutralize hepatitis E virus (HEV) recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine. According to recent research published in the journal...

Hepatitis C virus NS4 uses subversive tactics to thwart Th1 response.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus NS4 uses subversive tactics to thwart Th1 response. According to recent research published in the European Journal of Immunology, "the majority of hepatitis C virus (HCV)...

Interleukin-18-binding protein staunches inflammatory response in mouse livers.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Interleukin-18-binding protein staunches inflammatory response in mouse livers. "Interleukin (IL)-18 binding protein (IL-18BP) is a natural inhibitor of the pleiotropic cytokine IL-18. To study the...

Antisense suppression of DDEFL1 blocks hepatocellular carcinoma cell growth.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Antisense suppression of DDEFL1 blocks hepatocellular carcinoma cell growth. According to a study from Japan, "to disclose mechanisms of hepatocellular carcinogenesis and to identify novel...

Keratin polypeptide gene deletions heighten susceptibility to liver injury.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Keratin polypeptide gene deletions in mice heighten susceptibility to liver injury. According to published research from the United States, "keratin transgenic mouse models and the association of...

The face and eyes provide a means for occupational acquisition of hepatitis C.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The face and eyes provide a means for occupational acquisition of hepatitis C. "The risk of transmission of hepatitis C virus (HCV) infection is an important problem for the health care worker. HCV...

Viral hepatitis rates in Lower Saxony reflect common disease risk factors.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Viral hepatitis rates in Lower Saxony reflect common disease risk factors. "In Lower Saxony, a regional public health project for an enlarged surveillance of viral hepatitis was carried out from...

Many men would rather cope with STDs than use condoms, study finds.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Some men may not be willing to use condoms regularly even after seeking treatment for a sexually transmitted disease (STD) and acknowledging their protective value, according to a survey of low-income,...

Heterozygous disruption of the beclin 1 autophagy gene promotes tumorigenesis.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Heterozygous disruption of the beclin 1 autophagy gene promotes tumorigenesis. According to recent research published in the Journal of Clinical Investigation, "malignant cells often display defects...

Infant develops Kawasaki disease after hepatitis B vaccination.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- An infant developed Kawasaki disease after hepatitis B vaccination. "The known association between hepatitis B and vasculitis has been reported in rare cases in adults after hepatitis B vaccination....

Early treatment response foreshadows good outcomes for patients with HBV type C.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Early treatment response foreshadows good outcomes for patients with HBV type C. According to recent research from Japan, "genotype C of hepatitis B virus (HBV) has been shown to be associated with...

Four heat shock proteins are biomarkers for HCV-related liver cancer.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Four heat shock proteins are biomarkers for HCV-related liver cancer. According to recent research from Japan, "to identify proteins linked to the pathogenesis of hepatocellular carcinoma (HCC)...

Transgenic mice offer a new way to study hepatitis C virus immunopathology.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Transgenic mice offer a new way to study hepatitis C virus immunopathology. According to a study from the United States, "hepatitis C virus (HCV) is a major etiologic agent for chronic hepatitis...

Viral kinetics elucidate therapeutic response in chronic hepatitis C patients.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Viral kinetics elucidate therapeutic response in chronic hepatitis C patients. According to a study from Austria, "a substantial proportion of patients infected with hepatitis C virus (HCV)...

Patients with hepatitis B and C coinfections have a slightly higher cancer rate.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Patients with hepatitis B and C coinfections have a slightly higher cancer rate. "The clinical and virological significance of low-level viremia by hepatitis B virus (HBV) in hepatitis C virus...

Hepatitis B virus DNA integration occurs early during acute infection.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus DNA integration occurs early during acute infection. "The integration of hepatitis B virus (HBV) DNA in the liver of chronic HBV carriers has been documented extensively. However,...

Gamma-linolenic acid infusion occludes vessels that feed tumors.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Gamma-linolenic acid infusion occludes vessels that feed tumors. "Gamma-linolenic acid (GLA) is known to have selective tumoricidal action. In this study, the effect of lithium salt of GLA...

Antibody from liver disease patients slows oxidative muscle cell respiration.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Antibody from liver disease patients slows oxidative muscle cell respiration. "The effect of immunoglobulin G (IgG) purified from the sera of healthy persons and patients with primary biliary...

Hepatitis C virus core protein upregulates enzyme inhibitor to stop apoptosis.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein upregulates enzyme inhibitor to stop apoptosis. "The hepatitis C virus (HCV) core protein is considered to influence multiple cellular processes. We developed a human...

Interferon lowers the risk for liver cancer in patients with chronic hepatitis C.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Interferon lowers the risk for liver cancer in patients with chronic hepatitis C. According to recent research published in the Journal of Antimicrobial Chemotherapy, "hepatocellular carcinoma...

Treatment for HIV and HCV infections in hemophiliacs reviewed.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Treatment for HIV and HCV infections in hemophiliacs has been reviewed. "A substantial number of hemophilic patients are infected with both human immunodeficiency virus (HIV) and hepatitis C...

Typhoid/hepatitis A vaccine effective as booster dose in primed adults.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- A combined dual-chamber typhoid/hepatitis A vaccine was effective as a booster dose in hepatitis A primed adults. According to published research from Czech Republic and France, "Vivaxim is a...

HBsAg variants break tolerance in hepatitis B surface antigen mice.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Vaccination with cross-reactive, natural HBsAg variants breaks tolerance in hepatitis B surface antigen (HBsAg) transgenic mice. "Processing exogenous hepatitis B surface antigen (HBsAg) of the...

Chronic hepatitis C patients to benefit from guidance on new drugs and treatments.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- The U.K. National Institute for Clinical Excellence (NICE) has issued guidance on the use of interferon alpha, peginterferon alfa, a newer, longer-acting version of interferon alfa, which doesn't need...

FIBOSpect II introduced for detection of liver fibrosis.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Prometheus Laboratories Inc. announced the introduction of FIBOSpect II, a unique non-invasive diagnostic panel to aid in the detection of liver fibrosis in patients with chronic hepatitis C. This...

Rebetol Oral Solution available for treating pediatric hepatitis C.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corporation (SGP) announced the launch of Rebetol (ribavirin, USP) Oral Solution for use in combination with Intron A (interferon alfa- 2b, recombinant) Injection for treating pediatric...

Company completes independent test for hepatitis B in China.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Medical Services International, Inc., (MSITF) announced that the testing of the VScan Hepatitis B rapid test kit in The People's Republic of China is now complete. In December 2003, the regulatory...

Radiofrequency ablation and transcatheter chemoembolization are used for HCC.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Combined radiofrequency ablation (RF) and chemoembolization resulted in excellent 1- and 2-year survival rates in patients with hepatocellular carcinoma (HCC). "To evaluate short-term clinical...

Geranylgeranylation blockade is a new strategy for treating hepatitis C virus.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Geranylgeranylation blockade is a new strategy for treating hepatitis C virus. According to published research from the United States, "hepatitis C virus (HCV) RNA replication depends on viral...

Intrahepatic CD8 T-lymphocyte levels mark chronic hepatitis B treatment response.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Intrahepatic CD8 T-lymphocyte levels mark chronic hepatitis B treatment response. "Recognition of HBV-infected hepatocytes by CD8 T-lymphocytes is important for viral clearance. Expression of...

Neutrophils govern T-cell recruitment and hepatitis formation.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Neutrophils govern T-cell recruitment and hepatitis formation. "Leukocyte infiltration into the liver is paramount to the development of liver injury in hepatitis. Hepatitis occurring after the...

Quantitative analyses illuminate ribavirin and HCV RNA polymerase binding.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Quantitative analyses illuminate ribavirin and HCV RNA polymerase binding. According to a study from Canada, "ribavirin is a broad spectrum antiviral nucleoside that displays activity against a...

Those treated for HCV-related cancer have better odds if inflammation declines.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Those treated for HCV-related cancer have better odds if inflammation declines. According to researchers in Japan, "we examined whether sustained alleviation of inflammation as monitored by serum...

Exploratory phase II study: Gamma-1b is generally well tolerated.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., (ITMN) announced results of an exploratory phase II clinical trial evaluating interferon gamma-1b for the potential treatment of advanced liver fibrosis, or cirrhosis, caused by...

Loss of TIP30 heightens susceptibility to tumor development.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Loss of TIP30 heightens susceptibility to tumor development. "TIP30, also called CC3 or Htatip2, is a putative metastasis suppressor that promotes apoptosis and inhibits angiogenesis. Although...

Jennifer Giottonini named VP, corporate development.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Idun Pharmaceuticals, Inc., announced that Jennifer Giottonini has been appointed VP, corporate development. In this new position, Giottonini will be responsible for managing and expanding the...

Michael Markels to lead sales and marketing for neuropathic pain company.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- NeurogesX announced that it has appointed Michael Markels as senior director, sales and marketing. Markels, who has more than 13 years' experience in sales, marketing, and commercial development...

Hepatitis C virus subgenomic replicons can be grown in nonhepatic cells.
February 16, 2004... 2004 FEB 16 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus subgenomic replicons can be grown in nonhepatic cells. "Hepatitis C virus (HCV) infects liver cells and its replication in other cells is incompletely defined. Human hepatoma...

Consensus interferon beats out interferon-ribavirin regimens in HCV relapsers.
February 23, 2004... 2004 FEB 23 - (NewsRx.com & NewsRx.net) -- Consensus interferon beats out interferon-ribavirin regimens in hepatitis C virus (HCV) relapsers. According to a study from Italy, "management of HCV infection and related liver disease with...

Transient elastography offers a new noninvasive way to check liver fibrosis.
February 23, 2004... 2004 FEB 23 - (NewsRx.com & NewsRx.net) -- Transient elastography offers a new noninvasive way to check liver fibrosis. According to recent research from France, "chronic hepatitis is accompanied by progressive deposit of hepatic fibrosis,...

A major Chinese weight loss supplement has been linked to liver injury.
February 23, 2004... 2004 FEB 23 - (NewsRx.com & NewsRx.net) -- A major Chinese weight loss supplement has been linked to liver injury. "Dietary supplements have become very popular worldwide because they are believed to be safe with few side effects. Here, we...

Cyclooxygenase-2 inhibitors could be valuable for preventing liver cancer.
February 23, 2004... 2004 FEB 23 - (NewsRx.com & NewsRx.net) -- Cyclooxygenase-2 inhibitors could be valuable for preventing liver cancer. According to published research from Spain, "cyclooxygenase (COX) is a crucial enzyme in the biosynthesis of...

Interferon alters acute-phase reactions in patients treated for HCV infection.
February 23, 2004... 2004 FEB 23 - (NewsRx.com & NewsRx.net) -- Interferon alters acute-phase reactions in patients treated for HCV infection. According to a study from Hungary, "previously we observed elevation of the serum concentration of two acute-phase...

Apoptosis genes influence hepatitis C and B virus-related liver injury.
February 23, 2004... 2004 FEB 23 - (NewsRx.com & NewsRx.net) -- Apoptosis genes influence hepatitis C and B virus-related liver injury. "Bcl-2 oncoprotein regulates programmed cell death by providing a survival advantage to rapidly proliferating cells, and bax...