Hepatitis Weekly articles from August 2004

Hepatitis Weekly archives from August 2004

Trak-C offers rapid screening for hepatitis C virus core antigen.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Trak-C offers rapid screening for hepatitis C virus core antigen. "A new, sensitive enzyme immunoassay has been developed for detecting and quantifying total hepatitis C virus (HCV) core antigen in...

Human immunodeficiency virus fosters hepatitis C virus replication.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Human immunodeficiency virus fosters hepatitis C virus replication. According to recent research from the United States, "hepatitis C virus (HCV) was found to replicate in monocytes/macrophages...

Sequential therapy treats recurrent hepatitis C after liver transplantation.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Sequential therapy treats recurrent hepatitis C after liver transplantation. "Hepatitis C virus (HCV) infection invariably recurs after liver transplantation (LT), and sequels of chronic hepatitis...

Core antigen tests predict patient response to hepatitis C virus therapy.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Core antigen tests predict patient response to hepatitis C virus therapy. According to a study from France, "a new quantitative marker of hepatitis C virus (HCV) viremia based on the detection of...

Spontaneous clearance is common with hepatitis C virus genotype 3 infections.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Spontaneous clearance is common with hepatitis C virus genotype 3 infections. According to recent research published in the Journal of Medical Virology, "treating acute hepatitis C with interferon...

Microarray analysis identifies changes in liver gene expression.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Microarray analysis has been used to identify alcohol-induced changes in hepatic gene expression. "The mechanisms underlying alcoholic liver disease are not fully understood. It has been...

Tamoxifen metabolite R-isomer forms more DNA adducts in liver cells.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- A tamoxifen metabolite R-isomer forms more DNA adducts in liver cells. "The antiestrogenic drug tamoxifen forms DNA adducts in rat liver through two genotoxic metabolites, a-hydroxytamoxifen and...

Key hepatitis C-virus proteins rule interferon resistance mechanisms.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Key hepatitis C-virus proteins rule interferon resistance mechanisms. "Typically, a biphasic decay of viremia can be observed during the first few weeks of interferon-based treatment in patients...

Tests for hepatitis C virus infection show variable complementarity.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Tests for hepatitis C virus infection show variable complementarity. "We localized hepatitis C virus (HCV) C-100 protein in liver biopsies of 15 patients with chronic hepatitis C using...

Microparticles prolong the effect of glycyrrhetic acid in the liver.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Microparticles prolong the effect of glycyrrhetic acid in the liver. "The microparticles (MPs) of an anti-hepatotoxic drug, glycyrrhetic acid (GLA), were prepared using poly(DL-lactic...

Astilbin seizes control of tumor necrosis factor to abate liver injury.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Astilbin seizes control of tumor necrosis factor to abate liver injury. According to recent research published in the Journal of Pharmacy and Pharmacology, "the aim of this study was to evaluate the...

Hepatitis C virus associates with thrombocytopenia formation.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus associates with thrombocytopenia formation. "Chronic hepatitis C virus (HCV) infection has also been associated with the development of several extrahepatic alterations, including...

Hemophagocytic syndrome can erupt after liver transplantation.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Hemophagocytic syndrome can erupt after liver transplantation. According to a study from Spain, "The hemophagocytic syndrome is defined as a proliferation of phagocytic macrophages in the bone...

Novel human platelet septin SEPT8 is interaction partner of SEPT4.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- The novel human platelet septin SEPT8 is an interaction partner of SEPT4. "Septins are a family of GTP-binding proteins, which are essential for active membrane movement such as cytokinesis and...

Live and inactivated hepatitis A vaccines induced immunity in children.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Live attenuated and inactivated hepatitis A vaccines induced anti-HAV immune responses in children. "The immunogenicity of a live attenuated HAV vaccine and an inactivated HAV vaccine was compared....

Methods predict hepatitis A vaccination in men who have sex with men.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Scientists have developed methods predictive of hepatitis A vaccination in a sample of men who have sex with men. According to recent research published in the journal Health Education Research,...

Deficit in dendritic cell-T cell interaction crucial in hepatitis B.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- A selective functional deficit in dendritic cell-T cell interactions is a crucial mechanism in chronic hepatitis B virus infection. "A defect in specific T cell immunity has long been assumed to be...

CHMP recommends approval of shorter course of PegIntron/Rebetol therapy.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Schering-Plough Europe reported the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has issued a positive opinion recommending approval of a shorter 24-week course...

HCV screening for drug users/transfusion patients only is most cost-effective.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus screening for drug users and transfusion patients only is the most cost-effective. According to recent research published in the journal Gastroenterologie Clinique Et Biologique,...

History of intravenous drug use strongest predictor for HIV/HCV coinfection.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- A history of intravenous drug use is the strongest predictor for HIV/HCV coinfection. "The declining incidence of AIDS-related opportunistic diseases among people with HIV infection has shifted the...

Kinectin splicing in HCC characterized.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Kinectin splicing has been characterized in tissue from HCC patients. "To extend the search for hepatocellular carcinoma (HCC)-associated antigens with immunogenicity for clinical applications,"...

PIN1 overexpression/beta-catenin gene mutations distinct oncogenic events in HCC.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- PIN1 overexpression/beta-catenin gene mutations are distinct oncogenic events in hepatocellular carcinoma. "The peptidyl-prolyl-isomerase, PIN1, upregulates beta-catenin by inhibiting its...

TWEAK expression may play a central role in liver cancer proliferation.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- TWEAK expression may play a central role in liver cancer proliferation. According to a study from Japan, "tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a member of the TNF...

Hepatitis C virus core binding to T cell gC1qR impairs Lck and Akt activation.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core binding to T cell gC1qR impairs Lck and Akt activation. According to recent research from the United States, "complement plays a pivotal role in the regulation of innate and...

Immunoglobulin GM genotype heightens susceptibility to hepatitis C infection.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Immunoglobulin GM genotype heightens susceptibility to hepatitis C infection. "Hepatitis C virus (HCV) is a major health problem, affecting over 170 million people worldwide. HCV causes a wide...

Safety needle devices maker settles antitrust suit against Becton Dickinson.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Retractable Technologies, Inc., (AMEX:RVP) announced that it has settled its longstanding federal antitrust suit against Becton Dickinson (BD) for $100 million in cash. After legal fees and other...

Acquisition of Integrity Healthcare Services complete.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Priority Healthcare Corporation (NASDAQ:PHCC) announced that it has closed the acquisition of Integrity Healthcare Services. Integrity Healthcare Services is a specialty infusion pharmacy with 23...

Several new proteins are implicated for causing fatty liver.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Several new proteins are implicated for causing fatty liver. According to a study from the Netherlands, "the inbred HcB19 mouse strain expresses a truncated form of thioredoxin interacting protein...

FGFs enriches embryonic liver cultures for hepatic progenitors.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Fibroblast growth factors enrich embryonic liver cultures for hepatic progenitors. According to recent research from the United States, "Fibroblast growth factors (FGFs) play an important role in...

Washington state authorizes liver transplants at medical center.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Swedish Medical Center received approval from the Washington State Department of Health for its Certificate of Need application to establish a new adult liver transplant program on Swedish's First Hill...

Hepatitis C virus core protein amino acids hold the key to viral localization.
August 2, 2004... 2004 AUG 2 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein amino acids hold the key to viral localization. According to published research from Japan, "hepatitis C virus (HCV) core protein is suggested to localize to the...

Breath carbon monoxide measures the effects of ribavirin on red blood cells.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Breath carbon monoxide measures the effects of ribavirin on red blood cells. According to a study from the United States, "a major side effect of ribavirin (RBV) treatment is anemia. While this...

Black American patients with HCV genotype 1 respond to combination therapy.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Black American patients with HCV genotype 1 respond to combination therapy. According to published research from the United States, "Black Americans (blacks) have a high prevalence of chronic...

DDB cloaks the true effects of new drugs on liver enzyme levels.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- DDB cloaks the true effects of new drugs on liver enzyme levels. "We report 13 patients (10 with chronic hepatitis C, 1 with chronic hepatitis B, 2 with nonalcoholic steatohepatitis) with...

Pegylated interferon prevents the chronicity of hepatitis C virus infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Pegylated interferon prevents the chronicity of hepatitis C virus infection. According to recent research from the United States, "pegylated interferon alpha (PEG IFN-alpha) improves sustained...

Phosphorothioate di- and trinucleotides abate hepatitis B virus replication.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Phosphorothioate di- and trinucleotides abate hepatitis B virus replication. According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "several nucleoside analogs...

Hepatic ASC treated with TACE using degradable starch microspheres.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Transcatheter arterial infusion chemotherapy with degradable starch microspheres (DSM) can be effective for adenosquamous carcinoma (ASC) patients. Physicians in Japan described their experience...

Doppler images of the central retinal artery mark worsening liver disease.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Doppler images of the central retinal artery mark worsening liver disease. According to scientists in Germany, "retrobulbar-ocular circulation provides an opportunity to assess the terminal...

Novel glycolipids rally host defense mechanisms against viral hepatitis.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Novel glycolipids rally host defense mechanisms against viral hepatitis. "Alpha-galactosylceramide is a glycolipid derived from marine sponges that is currently in human clinical trials as an...

Supply company signs agreement with Bayer Diagnostics.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Novation, the supply company of VHA Inc. and the University HealthSystem Consortium, has signed an agreement with Bayer HealthCare LLC, Diagnostics (NYSE:BAY) for molecular diagnostics products and...

Hepatitis B surface antigen seroclearance favors clinical outcomes.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Hepatitis B surface antigen seroclearance favors clinical outcomes. According to a study from the Peoples Republic of China, "few studies have examined Chinese patients with chronic hepatitis B who...

siRNA deal expanded, candidates chosen for development against HIV.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Acacia Research Corporation (CBMX, ACTG) announced that its CombiMatrix group and collaboration irsiCaixa have entered into a 3-year research, development, and licensing agreement and have chosen two...

DNase gamma has important role in Fas-independent apoptotic DNA fragmentation.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- DNase gamma plays an important role in Fas-independent apoptotic DNA fragmentation in hepatocytes. According to recent research from Japan, "Endonuclease-induced DNA fragmentation is a hallmark of...

Obese patients with nonalcoholic fatty liver disease benefit from weight loss.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Obese patients with nonalcoholic fatty liver disease benefit from weight loss. "The effect of significant weight loss on nonalcoholic fatty liver disease remains unclear. In this case series of 36...

Lipid peroxidation derivatives inhabit cancer-prone livers.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Lipid peroxidation derivatives inhabit cancer-prone livers. "Increased oxidative stress and lipid peroxidation (LPO) are implicated in multistage carcinogenesis. Recent studies have shown that...

Novel agent shows promise as tacrine prodrug.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A novel agent shows promise as a potential tacrine prodrug. In a recent study from China, "9-[P-(N,N-dipropylsulfamide)]benzoylamino-1,2,3,4-4H-acridine (PTHA) was synthesized as a prodrug to...

Drug-induced mutants guide the development of new HCV protease inhibitors.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Drug-induced mutants guide the development of new HCV protease inhibitors. "BILN 2061 is a novel, specific hepatitis C virus (HCV) NS3 serine protease inhibitor discovered by Boehringer Ingelheim...

Viral disease-focused company provides preliminary second quarter results.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc., (VLGC) announced that it is lowering revenue guidance for the full year 2004 primarily due to postponement of the start of a significant, late-stage clinical trial by a major...

Solid organ transplantation in HIV-infected patients feasible in era of HAART.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Solid organ transplantation in HIV-infected patients is becoming feasible in the era of highly active antiretroviral therapy. According to a study from the U.S., "HIV is generally regarded as an...

Foundation launches major initiative to prevent spread of HIV.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- In an important step toward reversing the HIV/AIDS epidemic in sub-Saharan Africa, Safe Blood for Africa Foundation has launched a major program to distribute millions of "rapid" blood transfusion test...

Assay proven to ID previously undedectable hepatitis B blood donations.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (NASDAQ:CHIR) announced the results of a multicenter trial of the Procleix Ultrio Assay. The data was presented at a symposium at the International Society of Blood Transfusion...

Hepatitis as travelers' disease reviewed.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Researchers review hepatitis as a travelers' disease in a recent issue of Internist. According to research from Germany, "Every year over 50 million people travel from industrialized countries to...

MBI-3253 demonstrates potent activity against hepatitis C virus surrogate.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Micrologix Biotech Inc. (MGIXF) announced the publication of results demonstrating the potent efficacy of MBI-3253 (celgosivir) against the widely accepted surrogate model of the hepatitis C virus...

Preclinical data presented on anticancer agents, immunomodulatory molecules.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Bioniche Life Sciences, Inc., (BNC), a fully-integrated human and animal biopharmaceutical company, was among the presenters at the 12th International Congress of Immunology and 4th Annual Conference of...

Barriers to hepatitis B vaccination in Korean Americans identified.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A scientist has identified barriers to hepatitis B vaccination in Korean American children in immigrant families. According to published research from the United States, "This study examined social...

Novel cis-acting element facilitates minus-strand DNA synthesis during HBV RT.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- A novel cis-acting element facilitates minus-strand DNA synthesis during hepatitis B virus reverse transcriptase. According to a study from South Korea, "Hepadnaviruses replicate through reverse...

Chimpanzees infected hepatitis C lack dendritic cell impairment.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Chimpanzees chronically infected with hepatitis C virus lack phenotypic and functional impairment in dendritic cells. "Dendritic cells (DCs), which are potent antigen-presenting cells (APCs), are...

Clearance of hepatitis C viremia associated with cellular immunity.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- The clearance of hepatitis C viremia is associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in a prisons study cohort. According to a...

GSK hepatitis C research collaboration concludes.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Biota Holdings, Ltd., (BTA) announced its U.S. subsidiary Biota, Inc., was notified by GlaxoSmithKline (GSK) their 2-year research collaboration on novel hepatitis C drugs would not be extended beyond...

Ethnicity, gender, and age influence the formation of primary liver cancer.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Ethnicity, gender, and age influence the formation of primary liver cancer. "Recent research suggests an increase in the incidence of hepatocellular carcinoma (HCC) in the United States, which may...

Synthetic drug orders of magnitude better than naturally occurring analogue.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Which is better, the original or a forgery? In this case the comparison works in favor of the "imitation": New York chemists set about copying a compound from sea sponges in the lab. The compound is...

Chronic inflammation contributes to the formation of hepatocellular carcinoma.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Chronic inflammation contributes to the formation of hepatocellular carcinoma. "Accumulation of genetic alterations in hepatocarcinogenesis is closely associated with chronic inflammatory liver...

Hepatitis B virus X protein modulates Wnt/beta-catenin in hepatoma cells.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein modulates Wnt/beta-catenin in hepatoma cells. According to recent research published in the journal Hepatology, "Wnt/beta-catenin signaling contributes to diverse...

Hepatocellular carcinomas contain effective immune escape mechanisms.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Hepatocellular carcinomas contain effective immune escape mechanisms. "Hepatocellular carcinoma represents an increasing therapeutic challenge due to its high incidence and early metastasis....

Weight reduction ameliorates nonalcoholic steatohepatitis.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Weight reduction ameliorates nonalcoholic steatohepatitis. According to a study from Japan, "a 65-year-old woman was admitted to our hospital for an investigation of liver dysfunction. She had mild...

Basiliximab does not reduce rejection risk in pediatric patients.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Treatment with basiliximab does not lower the risk of rejection for pediatric liver transplant recipients. "Basiliximab is a monoclonal antibody that binds to the a subunit (CD25) of the...

Surgical strategy devised for HVOB after living-donor transplants.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- An effective surgical strategy has been formulated for treatment of HVOB in living-donor liver graft recipients. "The incidence of hepatic venous complications in partial liver transplantation is...

c-Fos mediates c-Myc-induced apoptosis in human liver cancer cells.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- c-Fos mediates c-Myc-induced apoptosis in human liver cancer cells. "The proto-oncogene c-myc encodes a transcription factor that plays a pivotal role in cell proliferation, differentiation, and...

Interrupted angiogenesis attenuates liver cancer progression in mice.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Interrupted angiogenesis attenuates liver cancer progression in mice. "It has been shown that angiogenesis plays an important role not only in tumor growth, but also in early carcinogenesis. The...

Interleukin-1 beta subdues human multidrug resistance protein 2 in liver cells.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Interleukin-1 beta subdues human multidrug resistance protein 2 in liver cells. According to a study from Japan, "the human multidrug resistance protein 2 (MRP2/ABCC2), expressed on the bile...

Indocyanine green identifies hepatic hydrothorax in the absence of ascites.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Indocyanine green identifies hepatic hydrothorax in the absence of ascites. "Hepatic hydrothorax in the absence of ascites is a rare complication of liver cirrhosis. A 56-year-old woman was referred...

Blacks receive transplants at disproportionately low rates.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Black people in the United States have reduced access to many medical therapies, and liver transplantation is one area where such disparity is suspected to exist. A new study shows that black...

Extended hypothermic machine perfusion impedes liver graft survival.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Extended hypothermic machine perfusion impedes liver graft survival. "Liver transplantation is often the only effective treatment for end stage liver diseases resulting from cirrhosis, hepatitis,...

Pericardial effusion is a rare feature of hepatitis C virus infection.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- Pericardial effusion is a rare feature of hepatitis C virus infection. According to published research from the United States, "a liver transplant recipient with hepatitis C presented with...

GB virus B p13 protein and hepatitis C virus p7 protein share partial homology.
August 9, 2004... 2004 AUG 9 - (NewsRx.com & NewsRx.net) -- GB virus B p13 protein and hepatitis C virus p7 protein share partial homology. "Although responsible for a major health problem worldwide, hepatitis C virus is difficult to study because of the...

T-cell repertoire returns to normal in HAA recovery.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- T-cell repertoire was seen to return to normal in hepatitis-associated aplastic anemia recovery. "Hepatitis-associated aplastic anemia (HAA) is a syndrome of bone marrow failure following an acute...

Expression of HCV core protein impairs DNA repair in human hepatoma cells.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- The expression of hepatitis C virus core protein impairs DNA repair in human hepatoma cells. Researchers from Belgium explain, "Several studies have documented the important association between...

HBV genotypes and precore and core mutants studied in Brazilian patients.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- HBV genotypes and precore and core mutants have been studied in Brazilian patients. "A method for genotyping hepatitis B virus by partial HBsAg gene sequencing with primers common to all known...

Enrichment technique to detect hepatitis-specific T cells studied.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- A new enrichment technique to detect tetramer-positive, hepatitis C-specific T cells has been analyzed. According to a study from England, "A major breakthrough in cellular immunology has been the...

HCV associated with diabetes after kidney transplant in patients on tacrolimus.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- HCV was found to be associated with diabetes following kidney transplantation in patients using tacrolimus. "The objective of this study was to evaluate the association between previous hepatitis...

Pharma company reports progress in aurora kinase program for treatment of cancer.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- Rigel Pharmaceuticals, Inc., (NASDAQ:RIGL) announced progress in its aurora kinase inhibition program, targeting cancer cell proliferation. Rigel announced that it has identified R763 as a lead...

Hepatic CYP isoforms inhibited by mGluR5 antagonists.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- Novel mGluR5 antagonists can be used to selectively inhibit certain hepatic CYP isoforms. "Characterization of new chemical entities for their potential to produce drug-drug interactions is an...

New breed of vaccine-producing plants aims to fight human diseases worldwide.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- At his presentation at the annual meeting of the American Society of Plant Biologists (ASPB) in Lake Buena Vista, Florida, Arizona State University Professor Charles J. Arntzen explained the newest...

Drug company reports lower sales and earnings for 2004 second quarter.
August 16, 2004... 2004 AUG 16 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corporation (SGP) has reported financial results for the 2004 second quarter, including lower comparative sales and earnings versus the 2003 period. The financial results reflect...