Blood Weekly articles from September 2008

Blood Weekly archives from September 2008

New acute myeloid leukemia study findings have been reported from J. Sierra et al.(Clinical report)
September 4, 2008... "Patients with acute myeloid leukemia (AML) are often neutropenic as a result of their disease. Furthermore, these patients typically experience profound neutropenia following induction and/or consolidation chemotherapy and this may result in...

New angiolymphoid hyperplasia research from M.K. Varshney et al outlined.
September 4, 2008... "Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings and regional cervical lymphadenopathy," researchers in New Delhi, India report (see also Angiolymphoid Hyperplasia). "The disease is...

Investigators at Thomas Jefferson University target appendicitis.
September 4, 2008... In this recent report, researchers in the United States conducted a study "To assess computed tomographic (CT) signs that have been described in published studies for the diagnosis of appendicitis to identify independent findings that predict...

New blood components findings from Juntendo University, Medical Department described.
September 4, 2008... According to a study from Hongo, Japan, "ABO-incompatible blood transfusions attributable to inadequate identification (ID) of the patient or the blood unit are among the most serious of transfusion hazards. It has been unclear whether a...

Research on blood components published by M. Ghio et al.
September 4, 2008... According to a study from Genoa, Italy, "Over the past decades, the weight of the published literature demonstrates that blood transfusions can induce clinically significant immunosuppression in recipients. Several studies showed significant...

New enzyme research findings from Medical University of Graz described.(Report)
September 4, 2008... According to recent research from Graz, Austria, "Apheresis technology has made tremendous progress up to the development of automated blood component collection, which offers increased efficiency in donor blood use, but the concern about the...

Research from K.J. Ho et al broadens understanding of hypotension.
September 4, 2008... "Compared with standard donors, kidneys recovered from donors after cardiac death (DCD) exhibit higher rates of delayed graft function (DGF), and DCD livers demonstrate higher rates of biliary ischemia, graft loss, and worse patient survival....

Research from University of Miami has provided new information about life sciences.
September 4, 2008... "One of the most complicated issues that surgeons face, in the care of burn patients, is infection," scientists in the United States report (see also Life Sciences). "This includes both superficial and systemic infections. Systemic...

Studies from University of the West Indies describe new findings in life sciences.
September 4, 2008... According to recent research from Kingston, Jamaica, "The investigation of presumed neutropenia places a. burden on the health services, especially those of developing countries, including Jamaica. This may be because the normal ranges used in...

Studies from Queen Elizabeth Hospital reveal new findings on lymphoma.
September 4, 2008... "IgG4-related sclerosing disease is a recently recognized inflammatory lesion frequently involving pancreas, submandibular gland, lacrimal gland, and lymph node. We report 3 cases of ocular adnexal lymphoma arising in IgG4-related chronic...

New lymphopenia study results reported from Chinese University of Hong Kong.
September 4, 2008... "Severe Acute Respiratory Syndrome (SARS) outbreak in 2002-03 caused morbidity in over 8000 individuals and mortality in 744 in 29 countries. Lymphopenia along with neutrophilia was a feature of SARS, as it is in respiratory syncytial virus...

Studies from University of Toronto provide new data on malaria.(Report)
September 4, 2008... "Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria...

Research results from Karolinska University update understanding of myelodysplastic syndrome.
September 4, 2008... " To assess the effect of erythropoietin (EPO) plus granulocyte-colony stimulating factor (G-CSF) treatment on survival and leukemic transformation in myelodysplastic syndrome (MDS). Patients and Methods We compared the long-term outcome of...

Research from P.A. Chandra et al broadens understanding of neutropenia.
September 4, 2008... "Felty's syndrome is regarded as a severe variant of rheumatoid arthritis (RA) that develops in less than 1 % of patients with RA. It consists of a triad of RA, splenomegaly, and leukopenia, which tends to develop after a long course of RA,"...

New Data Support Earlier Suggested Guidance for Levels of Cell-Mediated Immunity in Pediatric Liver Transplant Patients.
September 4, 2008... Israeli et al.,* in an article just published in the peer-reviewed journal Liver Transplantation, have further developed our understanding of the clinical potential of monitoring cell- mediated immunity in pediatric liver-transplant patients...

Vermillion Announces Publication of Data Supporting Its Peripheral Artery Disease Diagnostic Test Program.
September 4, 2008... Vermillion, Inc. (NASDAQ:VRML), a molecular diagnostics company, announced the publication of data supporting its peripheral artery disease (PAD) diagnostic program. The results were published in the August, 2008 issue of the peer-reviewed...

Studies from T. Utsumi et al provide new data on sepsis.
September 4, 2008... According to recent research from Yokohama, Japan, "The mechanism of pseudoaneurysm formation caused by prolonged sepsis is thought to be related to the vascular endothelium being directly invaded and broken by bacteria. Moreover, matrix...

Researchers from Duke University describe findings in sickle cell anemia.(Report)
September 4, 2008... According to recent research published in the American Journal of Obstetrics and Gynecology, "The purpose of this study was to identify morbidity that is associated with sickle cell disease (SCD) in pregnancy. The Nationwide Inpatient Sample...

New spinal cord injury data have been reported by scientists at Virginia Commonwealth University.
September 4, 2008... "Few therapies have consistently demonstrated effectiveness in preserving 0, delivery after spinal cord injury (SCI). Perfluorocarbons (PFCs) offer great promise to carry and deliver Q, more efficiently than conventional measures," researchers...

Recent findings in stomach cancer described by H. Kim and colleagues.
September 4, 2008... "The precise localization of target lymph nodes during laparoscopic biopsy can often be technically challenging. The purpose of this series was to report 2 patients who successfully underwent laparoscopic para-aortic lymph node sampling with...

New Data Support Role for Monitoring of Cell-Mediated Immunity in Adult Patients Following Renal Transplantation.
September 4, 2008... A recently published article by Sanchez-Velasco et al.* in Clinical Transplantation has expanded our understanding of the clinical potential of monitoring cell-mediated immunity in adult patients at risk for organ rejection or infection...

New findings from Northwestern University describe advances in cancer prognosis.
September 4, 2008... New investigation results, 'Perinucleolar compartment prevalence is a phenotypic pancancer marker of malignancy,' are detailed in a study published in Cancer. According to recent research published in the journal Cancer, "The perinucleolar...

Report summarizes enzyme research study findings from Baylor College of Medicine, Department of Pediatric Gastroenterology.(Report)
September 4, 2008... Data detailed in 'Pathophysiology of LPS-induced gastrointestinal injury in the rat: role of secretory phospholipase A2' have been presented. "A hydrophobic layer of phosphatidylcholine (PC) overlies and protects the surface of the...

Research results from Shiraz University of Medical Sciences, Department of Pediatrics update understanding of life sciences.
September 4, 2008... Current study results from the report, 'Visceral leishmanisis in paediatrics: a study of 367 cases in southwest Iran,' have been published. According to recent research from Iran, "Kala-azar (visceral leishmaniasis [VL]) is endemic in southern...

Data from Wonkwang University, Department of Internal Medicine provide new insights into lung cancer therapy.(Report)
September 4, 2008... Research findings, 'Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases,' are discussed in a new report. "Arsenic...

Study data from Columbia University update knowledge of neutropenia therapy.(Report)
September 4, 2008... New research, 'Neutropenia in 6 ethnic groups from the Caribbean and the U.S,' is the subject of a report. "Low white blood cell counts (WBC) or absolute neutrophil counts (ANC) may delay or prevent the completion of appropriate chemotherapy,...

Harvard University publishes research in sepsis.
September 4, 2008... Investigators publish new data in the report 'A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis.' According to a study from the United States, "We have recently shown that A3 adenosine...

Researchers from University of Texas describe findings in acute myeloid leukemia.
September 4, 2008... According to a study from the United States, "Acute myeloid leukemia with t(8;21)(q22;q22) is a distinct type of leukemia considered to have a favorable prognosis. However, some patients rapidly succumb to disease despite chemotherapy." ...

Research from M. Ouaissi and co-researchers provides new data on adenocarcinoma.
September 4, 2008... According to a study from Marseille, France, "Alterations in HDACs gene expression have been reported in a number of human cancers. No information is available concerning the status of HDACs in pancreatic cancer tumors." "The aim of the...

New adverse drug reactions study findings recently were published by researchers at St. Thomas' Hospital, Emergency Department.(Clinical report)
September 4, 2008... Researchers in London, the United Kingdom conducted a study "To evaluate the use of intravenous ketamine for procedural sedation in adults attending the emergency department. A prospective study was performed over a 2-year period in 92 patients...

Study results from University of Sydney in the area of aging published.
September 4, 2008... "Morphological changes in the hepatic sinusoid with old age are increasingly recognized. These include thickening and defenestration of the liver sinusoidal endothelial cell, sporadic deposition of collagen and basal lamina in the extracellular...

New aneurysm research reported from M. Lacombe and co-authors.(Report)
September 4, 2008... "The purpose of this study was to report our experience of surgical treatment of aortoiliac aneurysms in kidney transplant patients, to describe technical problems of this surgery, to evaluate its long-term outcome, and to discuss the place of...

New aneurysm research reported from W.C. Sternbergh and co-authors.(Clinical report)
September 4, 2008... "Recommended postoperative surveillance after endovascular aneurysm repair (EVAR) includes serial contrast-enhanced CT scans. The cumulative deleterious effect on renal function, radiation exposure, and significant cost of this surveillance...

Research from Karolinska University provides new data on aneurysm.(Clinical report)
September 4, 2008... According to recent research from Stockholm, Sweden, "The aim of this study was to analyze the clinical results of Guglielmi detachable bare coil (GDC) embolization of intradural saccular aneurysms (AAs) at a single center and to relate the...

Research from Yonsei University reveals new findings on aneurysm.
September 4, 2008... According to recent research published in the Journal of Neuroimaging, "We report a case of a 70-year-old man harboring a wide-necked thrombosed giant aneurysm of the left middle cerebral artery (MCA) on the MI segment." "The patient...

Research on aneurysm discussed by N. Paraskevas and co-researchers.(Clinical report)
September 4, 2008... According to recent research from Paris, France, "This prospective, observational study evaluated the safety and efficacy of superficial femoral artery autograft reconstruction in the treatment of popliteal-artery aneurysms in the absence of a...

Scientists at University of Insubria target aneurysm.(Report)
September 4, 2008... According to recent research from Varese, Italy, "This study was undertaken to assess the indications and effectiveness of the Amplatzer vascular plug (AVP) system in interventional radiology. Over the past year, we selected 12 patients (seven...

New angiology research reported from J.H. Rapp and co-authors.
September 4, 2008... "Microemboli occur frequently in patients with asymptomatic carotid atherosclerosis. In other vascular beds, microemboli are known to initiate an inflammatory response, causing organ dysfunction," researchers in the United States report (see...

New angiology study findings have been published by scientists at University of North Carolina.(Report)
September 4, 2008... "Twenty to thirty percent of patients with symptomatic chronic venous insufficiency (CVI) are found to have combined superficial and deep venous reflux on duplex testing. It is currently unclear whether endovenous; ablation (EVA) of the...

Reports summarize angiology study results from Seoul National University.(Report)
September 4, 2008... "Cerebral microbleeds (MBs) are known to be indicative of bleeding-prone microangiopathy and may predict incident intracerebral haemorrhage. However, there is controversy concerning the causal relationship between the presence of MBs and...

Research conducted at Columbia University has provided new information about angiology.
September 4, 2008... According to a study from the United States, "Posttraumatic internal carotid pseudoaneurysm is an infrequent but potentially life-threatening condition that complicates approximately one-third of blunt carotid injuries." "Other types of...

Study findings from Y.L. Chen et al broaden understanding of angiology.(Report)
September 4, 2008... " A fatal complication after liver transplantation is anastomotic embolization of the hepatic artery. In order to solve this problem, the portal venous arterialization (PVA) is used to reconstruct the hepatic arterial blood flow," scientists...

Investigators at University of Illinois, Medical Department target angiotensins.
September 4, 2008... "Increased growth and contraction of vascular smooth muscle cells (VSMCs) are major abnormalities in many vascular disorders. To investigate the signaling pathways that mediate these processes, we studied the expression of smooth muscle myosin...

Reports from INSERM add new data to research in angiotensins.
September 4, 2008... According to recent research from Paris, France, "Aminopeptidase A (APA) generated brain angiotensin III, one of the main effector peptides of the brain renin angiotensin system, exerting a tonic stimulatory effect on the control of blood...

Research findings from University of California update understanding of angiotensins.
September 4, 2008... According to recent research published in the American Journal of Hypertension, "Because all clinically approved angiotensin-receptor blockers (ARBs) have good safety profiles and share the ability to block angiotensin II type 1 (AT,) receptors...

Research from Georgetown University provides new data about angiotensins.
September 4, 2008... According to recent research from the United States, "The recycling of G-protein-coupled receptors (GPCR) to the cell surface after internalization plays an important role in the regulation of overall GPCR activity. The angiotensin II type I...

Studies from H.S. Bedair et al further understanding of angiotensins.
September 4, 2008... "Several therapeutic agents have been shown to inhibit fibrosis and improve regeneration after injury in skeletal muscle by antagonizing transforming growth factor-beta 1. Angiotensin receptor blockers have been shown to have a similar effect...

Reports by L.D. Berrizbeitia and co-researchers describe recent advances in aortic dissection.
September 4, 2008... According to a study from the United States, "Ascending aorta replacement for acute aortic dissection repair was carried out in a 29-year-old man without the use of blood or blood products. Intraoperative blood loss was minimized with the use...

Scientists at Shandong University target apoptosis.(Report)
September 4, 2008... "Ouabain is Na+/K+ ATPase inhibitor and an endogenous regulator of blood pressure, it has dual effect on vascular endothelial cells(VEC) cell growth and VEC apoptosis is contributed to vascular dysfunction involved in vascular remolding....

Study findings on apoptosis are outlined in reports from University of Heidelberg.
September 4, 2008... According to a study from Mannheim, Germany, "Marked reduction in apoptosis is a hallmark of early colon tumour growth and the vast majority of these tumours exhibit a loss of expression of the glycoprotein carcinoembryonic-antigen-related cell...

New findings from Niigata University in the area of arteriovenous fistula described.(Report)
September 4, 2008... According to recent research from Niigata, Japan, "Transvenous embolization (TVE) for the treatment of a cavernous sinus (CS) dural arteriovenous fistula (DAVF) occasionally causes cranial nerve palsy (CNP). Overpacking of coils is considered...

Study results from T. Ohta and colleagues broaden understanding of arteriovenous fistula.
September 4, 2008... According to recent research from Osaka, Japan, "The authors present a case of spinal dural arteriovenous fistula with fluctuations in symptoms following embolization. Superselective injection of 33% N-butyl cyanoacrylate, into the feeding...

New arthroplasty research from University of Calgary discussed.
September 4, 2008... In this recent study, researchers in Calgary, Canada conducted a study "To improve access to care, many jurisdictions have proposed waiting-time benchmarks and guarantees. We assessed the willingness of patients to consider changing their...

Research from RWTH Aachen University reveals new findings on arthroplasty.
September 4, 2008... According to a study from Aachen, Germany, " Hydrolytic debonding of the metal-cement interface is one of the main reasons for aseptic loosening in cemented hip arthroplasty. Materials and methods BiContact femur stems (CoCrMo-/TiAl6V4-alloy)...

Reports from University of California add new data to research in artificial chromosomes.
September 4, 2008... According to recent research published in the Journal of Neuroscience, "To elucidate the pathogenic mechanisms in Huntington's disease (HD) elicited by expression of full-length human mutant huntingtin (fl-mhtt), a bacterial artificial...

New artificial neural networks study findings have been published by S. Dosen and colleagues.
September 4, 2008... "We developed a method for use of accelerometers and force sensing resistors (FSRs) within an optimal controller of walking for hemiplegic individuals. The data from four dual-axis accelerometers and four FSRs were inputs, while six muscle...

Research from James Cook University, Medical Department has provided new information about atherosclerosis.
September 4, 2008... " Osteoprotegerin (OPG) and osteopontin (OPN) have been identified within unstable atherosclerosis and circulating concentrates have been linked to cardiovascular events. We studied the influence of OPG and OPN on endothelial adhesion molecule...

Study results from Afyon Kocatepe University, Medical Department provide new insights into atherosclerosis.
September 4, 2008... According to recent research from Afyon, Turkey, " Atherosclerotic vascular disease is a major cause of morbidity and mortality for patients with end-stage renal disease on maintenance hemodialysis. Early atherosclerotic changes of the arterial...

New atrial fibrillation study findings have been reported by researchers at Stanford University.
September 4, 2008... According to recent research published in the Journal of Cardiovascular Electrophysiology, "Efficacy, Safety, and Outcome of AF Ablation in Septuagenarians. Catheter ablation is an effective treatment for atrial fibrillation (AF)." "The...

New research on atrial fibrillation from I. Vanwijk and co-authors summarized.
September 4, 2008... "Published data suggest that patients with cerebral ischaemia and atrial fibrillation (CIAF) have higher inhospital mortality than patients with cerebral ischaemia of arterial origin ( CIAO). Data on long term risks are scarce," scientists in...

Research from Kyungpook National University, Medical Department reveals new findings on atrial myxoma.
September 4, 2008... According to recent research from South Korea, "Carney complex is a rare autosomal-dominant familial tumor syndrome that involves the triad of myxoma, mucocutaneous pigmentation, and endocrine overactivity. To the best of the authors'...

Data on B-cell lymphoma detailed by researchers at University of Debrecen.
September 4, 2008... "Recent results suggest that B cells may have multiple pathogenic roles in systemic sclerosis (SSc) and there may be increased incidence of B cell lymphomas in SSc. Here, we assessed the prevalence of lymphomas in a large SSc cohort,"...

Data on B-cell lymphoma published by A. Martinez and colleagues.
September 4, 2008... According to a study from the United States, "To assess the role of interferon regulatory factor (IRF) 8 in B-cell development and lymphomagenesis, we studied its expression in reactive lymphoid tissues.. its relationship to other B-cell...

New B-cell lymphoma data have been reported by L. Tracey and co-authors.
September 4, 2008... " Immunoglobulin gene somatic hypermutation is a biologically relevant and clinically useful prognostic factor in different types of low-grade B-cell lymphomas, including chronic lymphocytic leukemia, mantle cell lymphoma and splenic marginal...

Research reports on B-cell lymphoma from Mie University, Medical Department provide new insights.
September 4, 2008... According to recent research from Tsu, Japan, " De novo CD5-positive diffuse large B-cell lymphoma (CD5(+) DLBCL) is clinicopathologically and genetically distinct from CD5-negative (CD5(-)) DLBCL and mantle cell lymphoma. The aim of this...

Researchers at Bucknell University target B-cell lymphoma.(Report)
September 4, 2008... "We have used a mouse model based on overexpression of c-Myc in B cells genetically engineered to be self-reactive to test the hypothesis that farnesyl transferase inhibitors (FTIs) can effectively treat mature B cell lymphomas. FTIs are...

Findings from K.L. Rogers and co-authors provide new insights into bioluminescence.
September 4, 2008... "The construction and application of genetically encoded intracellular calcium concentration ([Ca2+](i)) indicators has a checkered history. Excitement raised over the creation of new probes is often followed by disappointment when it is found...

Reports on biomedicine findings from Case Western Reserve University provide new insights.
September 4, 2008... According to a study from the United States, "Heterogeneity in cardiac tissue microstructure is a potential mechanism for the generation and maintenance of arrhythmias. Abnormal changes in fiber orientation increase the likelihood of...

Reports outline biomedicine study findings from Osaka University.
September 4, 2008... According to a study from Suita, Japan, "The Protein Data Bank Japan (PDBj) curates, edits and distributes protein structural data as a member of the worldwide Protein Data Bank (wwPDB) and currently processes 2530 of all deposited data in the...

New blood pressure study results reported from Campinas State University, Medical Department.
September 4, 2008... According to a study from Campinas, Brazil, "The role of the central nervous system (CNS) in the control of hydrosaline homeostasis has been strikingly demonstrated by several studies. Our laboratory recently showed that centrally administered...

Report summarizes blood pressure study findings from Ulleval University.
September 4, 2008... Researchers in Oslo, Norway conducted a study "To assess the relative influence of genetic and environmental factors on retinal arterial tortuosity and the association between tortuosity and various health indices in healthy young to...

Reports from M.J. Pletcher et al highlight recent research in blood pressure.(Clinical report)
September 4, 2008... According to a study from the United States, "High blood pressure in middle age is a well-established risk factor for cardiovascular disease, but the consequences of low-level elevations during young adulthood are unknown. To measure the...

Reports from Yokohama City University, Medical Department describe recent advances in blood pressure.
September 4, 2008... " The aim of the present study was to measure peripheral blood flow (BF) with a new finger-occlusion plethysmograph (FOP) and to compare this to BF measured with a laser Doppler flowmeter (LDF). An additional objective was to investigate the...

New blood pumps study findings have been reported from University of New South Wales.
September 4, 2008... "Accurate noninvasive average flow and differential pressure estimation of implantable rotary blood pumps (IRBPs) is an important practical element for their physiological control. While most attempts at developing flow and differential...

Recent studies from National Defense Medical College, Medical College add new data to blood substitutes.
September 4, 2008... In this recent article published in the journal Annals of Surgery, scientists in Tokorozawa, Japan conducted a study "To investigate the efficacy of liposome-encapsulated hemoglobin (LHb) transfusion in rats undergoing lethal progressive...

New bone research data have been reported by N. Polisetty and co-authors.(Report)
September 4, 2008... According to a study from Hyderabad, India, "Mesenchymal stem cells (MSC) are self-renewing, multipotent cells that are present in many adult tissues, including bone marrow, trabecular bone, adipose, and muscle. The presence of such cells of...

Reports outline bone research study results from University of Michigan.
September 4, 2008... According to recent research from the United States, "Researchers in our laboratory have previously shown that ghrelin, a gastric peptide hormone, may regulate mesenchymal cell differentiation into adipocytes and myocytes. Here we show that...

Research on bone research described by D.E. Gwinn and colleagues.(Report)
September 4, 2008... According to recent research published in the journal Foot & Ankle International, "The distal bone bridge transtibial amputation technique requires additional intraoperative surgical steps when compared to the non-bone bridging technique....

Research on bone research published by scientists at Tsinghua University.
September 4, 2008... "Cancellous bone is a widespread structure in a creatural body, for instance, in the femoral head and spondyle. The damage evolution and crack growth of cattle cancellous bone were studied under three-point-bending load conditions," scientists...

Researchers at Semyung University release new data on bone research.
September 4, 2008... "We determined the effects of yolk water-soluble protein (YSP) on bone resorption. YSP potently suppressed osteoclastogenesis from bone marrow-derived precursor cells driven by tumor necrosis factor-alpha (TNF-alpha)," scientists in South Korea...

Study findings from Umea University broaden understanding of bone research.
September 4, 2008... According to recent research from Umea, Sweden, "The expressions of the calcitonin receptor (CTR), the calcitonin receptor-like receptor (CLR), the receptor activity-modifying proteins (RAMP) 1-3, and of the receptor component protein (RCP)...

Reports summarize brain infarction research from Ohio State University.
September 4, 2008... According to a study from the United States, "The importance of the site of occlusion and the presence or absence of collaterals on initial angiography in patients with acute ischemic stroke has been recognized. Qureshi recently proposed a...

Researchers at University of California publish new data on breast cancer.
September 4, 2008... "Little is known about the relationship between anatomic and functional contrast derived from intrinsic optical signals. In order to address this relationship, finite-element (FEM) forward simulations were compared to diffuse optical...

Scientists at University of Greenwich target breast cancer.
September 4, 2008... According to a study from Chatham, the United Kingdom, "This paper studies the possibility of distinguishing between benign and malignant masses by exploiting the morphology-dependent temporal and spectral characteristics of their microwave...