Blood Weekly articles from November 2004

Blood Weekly archives from November 2004

Analyses reveal siblings with rare double clotting deficiencies.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Analyses reveal siblings with rare double clotting deficiencies. According to recent research published in the American Journal of Hematology, "the combined presence in the homozygous state of more...

Organ procurement after poisoning deather studied.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Organ procurement after poisoning was the focus of a recent report. According to the report from Belgium, "There is an increasing gap between the number of patients on the waiting list and the...

Sphingolipidoses are relatively common and important health problem in Turkey.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Sphingolipidoses are a relatively common and important health problem in Turkey. "During the last 5 years 2057 children under the age of 5 with various neurologic symptoms with the suspected...

Scaffold topography alters cardiomyocyte network intracellular calcium dynamics.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Scaffold topography alters cardiomyocyte network intracellular calcium dynamics. According to recent research published in the American Journal of Physiology - Heart and Circulatory Physiology,...

Placental blood cell transplant feasible in children with sickle cell disease.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Placental blood cell transplantation is feasible in children with sickle cell disease. "The lack of healthy HLA-identical sibs limits the use of allogeneic hematopoietic cell transplantation in...

Multiresistant Acinetobacter baumannii outbreak occurred in surgical room.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Multi-resistant Acinetobacter baumannii outbreak occurred in a surgical room in Germany. "Outbreaks of Acinetobacter baumannii demonstrating multiple antibiotic resistance, including meropenem...

Loss of clone with FLT3 gene mutation at relapse does not improve AML prognosis.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The loss of a clone with an FLT3 gene mutation at relapse does not improve the prognosis of acute myeloid leukemia. According to recent research from Germany, "Internal tandem duplications (ITDs)...

Membrane Cofactor Protein identified as adenovirus receptor.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Membrane Cofactor Protein is identified as the adenovirus receptor. "A tandem mass spectrometry-based approach is demonstrated for detecting a receptor for Ad37, one of the causative agents for...

Slightly increased risk of ischemic stroke found with tamoxifen.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Researchers at Duke University Medical Center have found a slightly elevated risk of ischemic stroke due to a blood clot in the brain in patients treated with tamoxifen, a drug commonly prescribed both...

Phase I trial of Hematide initiated.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Affymax, Inc., announced that it has initiated a placebo controlled, phase I dose-finding clinical trial with its lead product candidate, Hematide, a peptide-based erythropoiesis stimulating agent (ESA)...

Study investigates cardiovascular responses to norepinephrine.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Researchers have investigated regional and temporal changes in cardiovascular responses to norepinephrine and vasopressin during continuous infusion of lipopolysaccharide in conscious rats. Reduced...

Company introduces low permeability AAA Device.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- W. L. Gore & Associates, Inc., a manufacturer of expanded polytetrafluoroethylene (ePTFE) vascular grafts and endovascular devices including the GORE EXCLUDER Bifurcated Endoprosthesis, announced...

Shear-dependent platelet aggregation unaffected by aspirin.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Shear-dependent platelet aggregation was shown to be unaffected by aspirin. According to a study from the United States, "Mechanisms of shear-induced platelet aggregation are not established. Data...

Augmented beta-endorphin is found in patients with coronary artery disease.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Researchers have investigated myocardial and peripheral concentrations of beta-endorphin before and following myocardial ischemia and reperfusion during coronary angioplasty. According to a study...

New laboratory provides key research into animal diseases.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- A new $58 million lab at Michigan State University will be a key to detecting diseases that start in animals but can be transmitted to people. The Diagnostic Center for Population and Animal Health...

Oral fluconazole safe/effective empiric treatment for neutropenic fever.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Oral fluconazole is a safe and effective empiric treatment for persistent neutropenic fever. According to a study from Israel, "Neutropenic patients who continue to be febrile despite adequate...

Antiestrogenic drug combinations may be used for glioblastoma malignancies.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Antiestrogenic drug combinations may be used for glioblastoma malignancies. According to researchers in Turkey, "The antitumor activity of nonsteroidal antiestrogens on C6 and low passage of human...

CD45 plays significant role in nuclear apoptosis by chloride channel regulation.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- CD45 plays a significant role in nuclear apoptosis by chloride channel regulation. According to published research from Canada, "Mitochondrial-perturbating agents such as toxic compounds induce...

Humic acid induces apoptosis in premyelocytic leukemia HL-60 cells.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Humic acid induces apoptosis in promyelocytic leukemia HL-60 cells. According to a study from Taiwan, "It has been shown that humic acid (HA), a phenolic polymer, exhibits pro-oxidant and cytotoxic...

Synthetic zeolites used for arsenate removal from pollutant water.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Synthetic zeolites are used for arsenate removal from pollutant water. "Arsenic is known to be a hazardous contaminant in drinking water that causes arsenical dermatitis and skin cancer. In the...

Company addresses possible reimbursement for VentrAssist LVAS.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Ventracor, Ltd., (VCR), said there was evidence the cost of its artificial heart devices used in its pending U.S. clinical trials would be fully reimbursed and there was potential for reimbursement at...

Oligonucleotide array technology rapidly detects foodborne pathogenic bacteria.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Oligonucleotide array technology rapidly detects foodborne pathogenic bacteria. According to a study from China, "A rapid and accurate method for detection for common pathogenic bacteria in...

Swedish company presents mass screening tests at investment conference.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Swedish blood diagnostics company LifeAssays Inc. presented its mass screening and point-of-care tests on Oct. 21 at the Windhover Information and Medtech Insight's "Investment In Innovation" Event, at...

Obesity surgery can cure diabetes, high blood pressure and other ills.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Patients who undergo obesity, or bariatric, surgery get far more than cosmetic benefits, many also shed fat-related ailments including diabetes, high blood pressure and high cholesterol, researchers...

Gli proteins up-regulate expression of basonuclin in basal cell carcinoma.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Gli proteins up-regulate the expression of basonuclin in basal cell carcinoma. "Tumorigenesis is frequently accompanied by enhanced rRNA transcription, but the signaling mechanisms responsible for...

Gen-Probe signs licensing agreements.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Gen-Probe (GPRO) has signed nonexclusive licensing agreements with bioMerieux and its affiliates that provide bioMerieux options to access Gen-Probe's ribosomal RNA technologies for certain uses, and...

Chiron announces blood-screening licensing agreement.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Chiron Corp. (CHIR) has granted a nonexclusive license to the blood transfusion centers of the German Red Cross (Blutspendediensten des Deutsche Rotes Kreuz, or DRK) for use of the company's HIV-1 and...

Clinical bovine mastitis diagnosed in a Prototheca zopfii outbreak.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Clinical bovine mastitis was diagnosed in a Prototheca zopfii outbreak. According to a study from Brazil, "Biopsy by fine needle aspiration together with microbiological examination and scanning...

Japan confirms 14th case of mad cow disease.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Japan confirmed its 14th case of mad cow disease on October 14, 2004, underscoring concerns about the fatal brain-wasting illness as Tokyo mulls relaxing cattle-testing standards that could allow the...

Well-differentiated breast tumors have more 16q loss than poorly differentiated.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Well-differentiated breast tumors have more 16q loss than poorly differentiated tumors. According to a study from the Netherlands, "Loss of heterozygosity (LOH) at the long arm of chromosome 16 is a...

Agreement signed for distribution of bacterial detection system in Japan.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Pall Corporation (NYSE:PLL) announced that it has finalized an agreement for Kawasumi Laboratories, Inc., to become the exclusive provider of the Pall eBDS (enhanced Bacterial Detection System) in...

Fruit and veg extract enhances cancer drug.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- A food extract could be used to improve the effects of an established cancer drug, scientists report. The drug, mitomycin C (MMC), is a well-known anticancer treatment used mainly against solid...

Scientists develop new drugs that improve survival after bone marrow transplant.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Parker Hughes scientists have developed a new technology capable of improving survival outcomes after bone marrow transplantation. The study was published in the prestigious medical journal, British...

Faulty furnace sends six to hospital in Connecticut.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Furnace problems at a three-story Connecticut apartment house sent six people to the hospital after carbon monoxide built up in the building. Police said two adults and 4 children complained of...

New catheter available for crossing chronic total occlusions.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Catheter technology company LuMend Inc. has launched a new re-entry catheter for peripheral crossing technology. According to LuMend, its new system, called the Outback Re-Entry Catheter, is the...

New treatment may help prevent blood clots.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Canadian cardiovascular research company Medicure (MCU) announced that preliminary results have shown significant potential for its newest drug, MC-45308, in preventing blood clots. The results...

Touching research: How white blood cells navigate.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- We all know the power of touch: A whack on the skull - or a hug - can convey more information than other forms of communication ever can. It turns out the same is true inside our bodies, where just the...

Cholesterol guidelines become a morality play about conflict of interest.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- They led influential medical groups, starred at prestigious meetings, published in top journals and were undisputed giants in their field. But when nine famous doctors advised the government...

Absolute guidelines needed for monitoring minimal residual disease in CML.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Absolute guidelines are needed for monitoring minimal residual disease in chronic myeloid leukemia. According to recent review in the journal Hematology, "Detection and monitoring of minimal...

Porcine circovirus type 2 from pigs was in Croatia detected and characterized.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Porcine circovirus type 2 from pigs was in Croatia was detected and characterized. According to a study from Croatia, "Porcine circovirus type 2 (PCV2) from the Circoviridae family has recently been...

Clinical investigators review, endorse phase 2 trials for deep vein therapy.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Agenix Limited [AGXLY] announced that clinical investigators to be involved in its phase 2 ThromboView deep vein thrombosis (DVT) clinical trial have met, reviewed and endorsed all aspects of the trial....

ZD9331 has minimal antitumor activity as 2[superscript]nd/3[superscript]rd line colorectal cancer therapy.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- ZD9331 yields minimal antitumor activity as a 2[superscript]nd or 3[superscript]rd line colorectal treatment. "This study investigated the efficacy, and tolerability of ZD9331 as second- or...

E-mail surveys assist investigation and response in conjunctivitis outbreak.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- E-mail surveys can assist the investigation and response in a conjunctivitis outbreak. "A conjunctivitis outbreak affecting more than 200 individuals occurred on a university campus in Evanston,...

SEEK1 polymorphisms not associated with Crohn disease in Newfoundland.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- SEEK1 polymorphisms that are associated with psoriasis are not associated with Crohn disease in Newfoundland. "Crohn's disease (CD) is an inflammatory bowel disease that is likely the result of an...

p53-dependent transcription exhibits on and off responses after genotoxic stress.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- p53-dependent transcription exhibits both on and off responses after genotoxic stress. According to published research from Estonia, "The p53 protein is a central player in cellular response to DNA...

Viral DNA damage in presence of RB, UV light may make normal repair less likely.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Viral DNA damage in presence of riboflavin and UV light may make normal repair less likely. Researchers in the United States are "developing a technology based on the combined application of...

HIV diagnostic proves effective in Dominican Republic trials.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Medical Services International (MSITF) announced that it has completed a series of testing of its VScan HIV 1&2 rapid test kit in the Dominican Republic, and the results showed 100% accuracy in terms of...

Chinese CDC attends HIV/AIDS training seminar.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Diagnostic test developer MedMira Inc. (MMIRF) announced a series of technical training seminars in collaboration with the Centers for Disease Control (CDC) in the People's Republic of China. These...

Life sciences company announces Nanobacteria blood test manufacturing agreement.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Nanobac Life Sciences, Inc., (OTCPK: NNBP) announced the signing of a manufacturing agreement with Medicorp, Inc., for the production of two blood tests for the detection of Nanobacteria. Nanobac...

Novel antiapoptotic protein X-linked IAP antagonists potential cancer therapy.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Novel antiapoptotic protein XIAP antagonists are a potential therapy for cancers overexpressing X-linked IAP. "Inhibitor of apoptosis (IAP) proteins are overexpressed in many cancers and have been...

Novel compounds exhibit antiviral and antitumor effects.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Novel compounds exhibit antiviral and antitumor effect. Novel platinum compounds and antiviral guanosine-type ligands are antiviral/antitumor. According to a study from Italy, "Platinum...

Emerging pathogen suggests amphibian trade should be closely monitored.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- An emerging pathogen in an introduced amphibian species suggests that the amphibian trade should be closely monitored. "Chytridiomycosis is an emerging fungal disease of amphibians responsible for...

County officials in Oklahoma look for cause of infections.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Health officials in Oklahoma's Johnston and Caddo counties are trying to the determine source of about 40 cases of staph infection that have affected residents in several cities. The infections are...

Mold found in nuclear weapons plant office.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Health and safety experts have been called in to battle a mold problem in a building at Oak Ridge, Tennessee's nuclear weapons plant that houses public affairs officers and union leaders. Mold and...

EBV is integrated between REL and BCL-11A in American Burkitt lymphoma cell line.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Epstein Barr Virus is integrated between REL and BCL-11A in the American Burkitt lymphoma cell line. "Epstein-Barr virus (EBV) initially isolated from the cultured Burkitt lymphoma (BL) cells, is...

Company announces clinical hold on TNFerade trials.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- GenVec (GNVC) announced that the U.S. Food and Drug Administration (FDA) has requested that clinical trials of TNFerade be placed on hold, pending review of information pertaining to a potential...

High serum SCC Ag predicts poor survival in esophageal cancer with esophagectomy.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Elevated serum levels of squamous cell carcinoma antigen predicts poor survival in advanced esophageal cancer after esophagectomy. According to recent research published in the World Journal of...

DaVita acquires three dialysis centers.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- DaVita, Inc., (DVA) announced that effective August 1, 2004, it acquired dialysis centers in California and Georgia serving approximately 220 patients. The transactions include two centers located...

Functional human coagulation factor XIII A-domain expressed in plants.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Functional human coagulation factor XIII A-domain was expressed in plants. "Coagulation factor XIII, a zymogen present in blood as a tetrAm (A(2)B(2)) of A- and B-domains, is one of the components...

Cangene reports earnings of 52 cents per share for fiscal 2004.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Cangene Corp. reported results for the year ended July 31, 2004. Revenues for the year were $156.9 million, down $29.3 million or 16% from fiscal 2003. Revenues were affected by the continued...

Cleveland stem cell investigators awarded $3.1 million.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The Center for Stem Cell and Regenerative Medicine in Cleveland has received two grants totaling $3.1 million from the U.S. National Institute on Aging to study the role of stem cells in aging. The...

Company raises $12 million to fund gene therapy.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- GENETIX Pharmaceuticals, Inc., has completed a $12 million private equity investment round to fund a phase I/II clinical trial of its pioneering LentiGlobin hemoglobin gene therapy for patients with...

Diagnostics firm secured new funding to develop new sensor technology.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Diagnostic systems developer LabNow, Inc., announced that it has raised $14 million in equity financing from a syndicate of private and venture investors led by George Soros, with the participation of...

Piccadilly chain recalls turnip greens after rat parts found.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Piccadilly Cafeterias, Inc., has recalled a brand of turnip greens sold at some of its 132 restaurants after a customer at a Georgia outlet bit into greens containing rat body parts. A county...

Expression of 7 ARP2/3 complex genes are decreased in gastric cancer.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The expression of 7 ARP2/3 complex genes are decreased in gastric cancers. "The Arp2/3 complex and filamins play important roles in organization of actin cytoskeleton, and thus in cellular...

KiSS-1 downregulation causes tumor invasion/worse prognosis in gastric cancer.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- KiSS-1 downregulation causes tumor invasion and a worse prognosis in gastric cancer. According to recent research from Japan, "KiSS-1 is a promising candidate tumor-suppressor gene and may play a...

Genomics company announces gene study in human embryonic stem cells.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Lynx Therapeutics(LYNX) announced an agreement with the American Type Culture Collection (ATCC) to study gene expression in certified human embryonic stem cells. Under this agreement, Lynx will...

Globin gene activation driven by protein complexes nucleated by GATA-1/GATA-2.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Globin gene activation is driven by protein complexes nucleated by GATA-1 and GATA-2. "How does an emerging transcriptional program regulate individual genes as stem cells undergo lineage...

New grant awarded for anemia treatment.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Gene therapy research company Mirus Bio announced that it has been awarded a $1.26 million, multi-year Phase II Small Business Innovation Research (SBIR) grant from the U.S. National Institutes of...

Deoxyribozymes exhibit the ability to silence disease-associated genes.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Deoxyribozymes will soon enter clinical trials. According to a recent report from Australia, "Deoxyribozymes (DNAzymes) comprise an exciting class of nucleic acid molecules that are capable of...

TNF-TNFR super-family gene SNPs associated with immune-mediated disease.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Tumor necrosis factor-TNF-receptor super-family gene single nucleotide polymorphisms are associated with immune-mediated disease. "The tumor necrosis factor (TNF) and TNF receptor (TNF-TNFR)...

Debate-guidelines for glycopeptide-resistant enterococci control have not worked.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The debate-guidelines for glycopeptide-resistant enterococci control have not worked. "Glycopeptide-resistant enterococci (GRE) have become a focus of concern in many countries because options for...

Group B rotaviruses have been circulating in Western India since 1993.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Group B rotaviruses have been circulating in Western India since 1993. According to a study from India, "Generally, group A rotaviruses are the most common cause of pediatric diarrhea. However,...

HIV-1 non-B subtypes from heterosexual transmission predominate in Scotland.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- HIV-1 non-B subtypes acquired from heterosexual transmissions predominate in Scotland. According to a study from Scotland, "Historically, subtype B viruses in men who have sex with men (MSM) and...

APOBEC3G incorporated into HIV-1 virions through viral/nonviral RNA interactions.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- APOBEC3G is incorporated into HIV-1 virions through viral and nonviral RNA interactions. "Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is a host cytidine deaminase...

Antisense U7 snRNAs and siRNAs targeting cyclophilin A inhibit HIV-1 replication.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Antisense U7 snRNAs and siRNAs targeting cyclophilin A inhibit HIV-1 replication. According to published research from Switzerland, "Human immunodeficiency virus 1 (HIV-1) multiplication depends on...

Dying cells drive the capacity of HIV-1 to kill noncycling primary CD4+ cells.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Dying, neighboring cells drive the capacity of HIV-1 to kill noncycling primary CD4+ cells. According to recent research published in the journal Cell Death and Differentiation, "CD4+ T-cell death...

HIV-1 infectivity enhanced by forming particle-mediated syncytia in CD4+ cells.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- HIV-1 infectivity is enhanced by forming particle-mediated syncytia in CD4+ cells. According to published research from Japan, "The infection and subsequent replication rates of human...

Host cell gene expression varies during HIV-1 latency or reactivation.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The host cell gene expression varies during HIV-1 latency or reactivation. "The existence of reservoirs of cells latently infected with human immunodeficiency virus (HIV) is a major obstacle to the...

Memantine protects hippocampal neuronal function in HIV-1 encephalitis.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Memantine protects hippocampal neuronal function in HIV-1 encephalitis. "Memantine, a low-to-moderate-affinity NMDA receptor antagonist, can be used to treat cognitive impairment associated with...

R5 HIV-1 replicates more efficiently in primary CD4+ cells than X4 HIV-1.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- R5 HIV-1 replicates more efficiently in primary CD4+ cells than X4 HIV-1. According to recent research from the United States, "In this report, we present evidence that R5 human immunodeficiency...

Structure of initiation complex of HIV-1 reverse transcription is not conserved.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- The structure of the initiation complex of HIV-1 reverse transcription is not conserved. According to a study from France, "HIV-1 reverse transcription is initiated from a tRNA(3)(Lys) molecule...

TSG101 mutations that inhibit PTAP or VPS28 binding block HIV-1 budding.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- TSG101 mutations that inhibit PTAP or VPS28 binding block HIV-1 budding. "Efficient human immunodeficiency virus type 1 (HIV-1) budding requires an interaction between the PTAP late domain in the...

Tumorigenesis by HHV-8 chemokine receptor vGPCR is accelerated by HIV-1 Tat.
November 4, 2004... 2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Tumorigenesis by the HHV-8 chemokine receptor vGPCR is accelerated by HIV-1 Tat. According to a study from the United States, "Human herpesvirus 8 (HHV-8), also called Kaposi's sarcoma (KS)...