Blood Weekly articles from May 2003

Blood Weekly archives from May 2003

Chaperone-rich tumor cell lysates show promise.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Tumor-derived chaperone-rich cell lysates (CRCL) could be the basis for an effective anti-cancer vaccine, researchers in the United States say. Yi Zeng and...

Irradiation improves tumor cell transgene expression.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Gamma irradiation does not impair transgene expression by leukemic cells, researchers report. "The majority of immunotherapy-based gene therapy protocols...

Blood poisoning vaccine ready for human trials.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A combined British and U.S. research team has developed the world's first vaccine against endotoxin, which is a key cause of blood poisoning and death after major surgery for cancer or heart disease....

Hemo-vasculogenesis occurs throughout human embryos.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Hematopoiesis occurs throughout human embryos, in concert with vasculogenesis. "During embryonic life, hematopoiesis occurs first in the yolk sac, followed by the aorto-gonado-mesonephric region,...

Novel fluorescence microplate assay shows leukodepletion efficacy.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A novel assay can detect low numbers of leukocytes in blood products. "In November 1999, universal leukoreduction of blood components was introduced in the UK to minimize the risk of variant...

Transplantation beneficial for thalassemia, sickle cell disease patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Umbilical cord blood transplantation is safe and effective for patients suffering from thalassemia or sickle cell disease. "Allogeneic bone marrow transplantation (BMT) from HLA-identical siblings...

Stem cells may be possible future treatment.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- One approach for future treatment of acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome (ARDS), could involve stem cells to replace dying lung cells, according to a...

Aranesp maintains hemoglobin levels in kidney disease patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Amgen (AMGN) announced preliminary results from a study evaluating the use of Aranesp (darbepoetin alfa) administered once per month to maintain target hemoglobin levels (10-12 g/dL) in chronic kidney...

Online support network available for anemia patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Anemia LifeLine announced that it has launched the Anemia Connections program, an online support network where patients, families, and caregivers can help each other cope with the physical and emotional...

Sulperazon is effective in about 64% of immunocompromised patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Immunocompromised patients given Sulperazon for fever responded to the antibiotic in many cases. According to a study from Russia, "The antibacterial activity of Cephoperazon/sulbactam (Sulperazon)...

Complications may occur after percutaneous transvenous mitral commissurotomy.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Complications, such as cardiac thromboembolism, may occur after percutaneous transvenous mitral commissurotomy. According to recent research from Japan, "A 50-year-old man was transferred to our...

Gene therapy potential seen in gamma-globin lentiviral vector.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Hematologists at St. Jude Children's Hospital, Memphis, Tennessee, have reported study data in the journal Blood that suggest a gamma-globin lentiviral vector could be effective in gene therapy for...

Blood, IV infusion warmer runs on batteries.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- The U.S. Military Forces in Iraq have an angel on their side. It's a medical device, called the Thermal Angel, that is being extensively used by the Marines to treat casualties in their portable...

Risk rises as medical treatment improves.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Living longer and better medical treatments such as organ transplants and cancer therapy are all paradoxically increasing our risk of blood poisoning, according to experts in bacterial infections...

Oregon blood plasma center cited twice by FDA before closure.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- The only blood plasma collection center in Salem, Oregon, was cited twice by the U.S. Food and Drug Administration (FDA) for safety violations before it voluntarily closed its doors, officials say. ...

Blood center receives first request for blood to help military.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Bonfils Blood Center has been asked to provide blood to help support the military blood needs during the current war in Iraq. Bonfils Blood Center, in conjunction with a national agreement made by...

Lymphocytes induce tolerance to blood group-like antigen.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Tolerance to a mammalian blood group-like carbohydrate antigen was induced by syngeneic lymphocytes expressing the antigen. According to a study from the United States, "Tolerance induction to...

Hematopoietic cells can reconstitute glomerular mesangial cells.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Hematopoietic cells can be used to reconstitute glomerular mesangial cells. "It was recently reported that crude bone marrow cells have the ability to differentiate into glomerular mesangial cells,"...

Factors predicting imatinib response identified.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Factors predicting the response to imatinib have been identified. According to recent research from the United States, "imatinib induces remissions in approximately 30% of patients with chronic...

Erythropoietin treated patients may develop a treatable autoimmune response.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Renal failure patients with anemia given erythropoietin alpha who develop pure red blood cell aplasia can be treated with cyclosporine for resolution of autoimmune response. According to a study...

Gene therapy boosts immume system against cancer.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Transfusions of genetically engineered blood cells could give bowel cancer patients a powerful boost against their disease, scientists from Cancer Research UK report. In a laboratory-based pilot...

Stem cell factor ameliorates liver damage in mice.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Stem cell factor ameliorates liver damage in mice. "Acute liver injury is a common cause of intensive care unit visits," according to recent research published in the journal Laboratory...

Anti-heparin-platelet factor 4 antibody is linked to thrombotic complication.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Hemodialysis patients have higher amounts of anti-heparin-platelet factor 4 antibody and this was linked to the risk for vascular access obstruction. "Since heparin is an anticoagulant commonly used...

15% Prevalence of chronic HBV infection found in blood donors in Kumasi, Ghana.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Hematologists with the U.K. National Blood Service quantified the risk of hepatitis B virus (HBV) transmission by transfusion in a hospital in Kumasi, Ghana. According to J.P. Allain and colleagues,...

Novel prominin membrane glycoprotein identified.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A novel prominin membrane glycoprotein has been identified. According to recent research from Germany, "prominin/CD133 is a 115/120-kDa integral membrane glycoprotein specifically associated with...

Natural alpha interferon-producing cells mature in response to infection.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Natural alpha interferon (IFN-alpha)-producing cells (IPCs) produce their signature cytokine and mature to dendritic cells in response to HIV infection. According to recent research from Japan, IPCs...

Vitamin C transforms mouse stem cells into heart muscle cells.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Vitamin C helped convert mouse embryonic stem cells growing in the laboratory to heart muscle cells, researchers report. "Although the findings of this study are very preliminary with respect to...

Primary bone marrow B-cell lymphoma should be considered in diagnosis.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Unusual hematology and bone marrow involvement must be examined carefully to include possibility of B-cell lymphoma. "Bone marrow involvement is infrequent at presentation in cases of diffuse large...

Results released supporting use of stem cells for bone disease.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Aastrom Biosciences, Inc., (ASTM) announced that the results of a study in which the company's Tissue Repair Cells (TRCs) were used to safely generate bone in a girl with the genetic bone disease...

An adenovirus infection of an allograft was cured by reducing immunosuppression.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A kidney transplant patient who developed an adenovirus infection in the graft was successfully treated simply by reducing immunosuppressive therapy. "One month after renal transplantation, a 60 yr...

Acute lymphocytic leukemia occurred after chronic myelocytic leukemia.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A case of chronic myelocytic leukemia changed to acute lymphocytic leukemia after interferon treatment. According to a study from the Peoples Republic of China, "We report a unique case of chronic...

Azidothymidine highly effective in combination with interferon-alpha.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Azidothymidine combined with interferon-alpha is highly effective against HIV- and AIDS-related lymphoma. "The survival of viral mediated lymphomas depends upon constitutive nuclear factor kappa B...

Single-step PCR assay finds and distinguishes Plasmodium parasites.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A novel single-step polymerase chain reaction (PCR) assay can find and distinguish between malaria parasite species in blood. "The ability to detect and differentiate between Plasmodium falciparum...

Heparan sulfate mediates binding of infected erythrocytes to endothelial cells.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Heparan sulfate mediates the binding of Plasmodium falciparum-infected erythrocytes to endothelial cells. P. falciparum "may cause severe forms of malaria when excessive sequestration of infected...

Variable P. falciparum merozoite protein phenotype enhances cell invasion.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Variable merozoite protein phenotype augments Plasmodium falciparum's ability to infect red blood cells. According to recent research from Australia, P. falciparum, the parasite "responsible for...

Cells behave differently in endothelial contact than migrating through barrier.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Blood monocytes in contact with human brain endothelial cells produce cytokines and maintain APC status, while those that migrate through the cell barrier do not; this may mean that the endothelial...

Repifermin trials demonstrate safety and efficacy.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that results from a phase II clinical trial demonstrate that repifermin (keratinocyte growth factor-2, KGF-2) is well tolerated and shows efficacy in...

Antibody-producing cells need stress.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Stressed out? It turns out B cells need to be stressed to ramp up their metabolic capacity to make antibodies in response to infection. In the April 2003 issue of Nature Immunology, researchers at...

Farnesyl transferase inhibitor induces apoptosis in drug resistant cells.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Drug resistant multiple myeloma may be treated with the farnesyl transferase inhibitor, FTI-277. "Mutations of the ras gene are among the most commonly identified transforming events in human...

Myeloablative stem cell rescue adds little benefit to high-dose chemotherapy.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Myeloablative stem cell transplantation adds little benefit to high-dose chemotherapy for multiple myeloma patients. Investigators in the Netherlands "compared the efficacy of intensified...

Stem cell transplant more effective than chemotherapy as first-line treatment.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Stem cell transplantation is more effective than standard chemotherapy as first-line therapy for patients with multiple myeloma, according to the first evidence-based review of transplant as a treatment...

Survival is lowered in patients with chromosome abnormalities.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Survival is lowered in myeloma patients with chromosome abnormalities. "The nonrandom recurrent nature of chromosome abnormalities in myeloma suggests a role for them in disease pathogenesis. We...

COX-2 specific inhibitors should be considered for postsurgical analgesia.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- COX-2 specific inhibitors should be considered for postsurgical analgesia, as they hold distinct advantages. "The role of the coxibs in the management of osteoarthritis and rheumatoid arthritis has...

Free AABB publication to help hospitals properly code for blood products.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- To assist hospitals and transfusion services personnel in obtaining proper reimbursement for blood and blood products, the American Association of Blood Banks (AABB), with support from the Advanced...

High-dose chemotherapy with stem cell autograft effective for children.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- High-dose chemotherapy with autologous stem cell transplantation can cure pediatric retinoblastoma. According to recent research from Germany, "children with metastatic retinoblastoma are...

Microsatellite instability and hMLH1 promoter hypermethylation are associated.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Richter syndrome, the transformation of lymphocytic leukemia to large B cell lymphoma, is associated with microsatellite instability and hypermethylation of hMLH1 gene. According to a study from...

Cationic isothiocyanates show promise for treatment.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Cationic isothiocyanates show promise for the treatment of sickle cell disease. "Although the molecular defect in sickle hemoglobin that produces sickle cell disease has been known for decades,...

Genes linked aorta-gonad-mesonephros stem cell emergence identified.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A pair of genes have been linked to the emergence of hematopoietic progenitors in mice. "The first adult-repopulating hematopoietic stem cells (HSCs) emerge in the mouse aorta-gonad-mesonephros...

Granulocyte-colony stimulating factor alters dendritic cell CD62L, CCR7 expression.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Granulocyte-colony stimulating factor (G-CSF) alters dendritic cell expression of CCR7 and CD62L. In a recent study from Australia, "changes in blood dendritic cell (BDC) counts (CD123(hi)BDC and...

Ikaros proteins involved in myeloid differentiation.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Ikaros proteins are involved in myeloid differentiation of hematopoietic cells. According to published research from the United States, "the Ikaros gene is alternately spliced to generate multiple...

Novel cell line grows in erythropoietin or interleukin-3 alone.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- A novel hematopoietic cell line can be successfully cultured using a single cytokine. "Erythropoiesis requires the stepwise action on immature progenitors of several growth factors, including stem...

Patent granted for methods of isolating precursors to insulin-producing cells.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- StemCells, Inc., (STEM) confirmed that the U.S. Patent Office has granted U.S. patent number 6,541,251 with claims covering methods for isolating pancreatic progenitor cells in mammals, including...

Antimicrobial prophylaxis unnecessary for autograft recipients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Antimicrobial prophylaxis is not necessary for autologous stem cell transplant recipients. According to published research from Taiwan, "the use of prophylactic antimicrobials during autologous...

Human metapneumovirus linked to lower respiratory tract disease.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Human metapneumovirus has been linked to lower respiratory tract disease in stem cell graft recipients. "Respiratory viruses are increasingly recognized as a cause of pneumonitis following...

Imatinib mesylate does not impair engraftment.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Imantinib mesylate does not appear to inhibit stem cell engraftment. According to published research from Singapore, "the main obstacles to successful hematopoietic stem cell transplantation for...

Liver damage risk can be acceptable for hepatitis patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- The risk of liver damage does not rule out stem cell transplantation for hepatitis patients. "Hepatitis B virus/hepatitis C virus (HBV/HCV) positive patients undergoing hemopoietic stem cell...

Low-intensity conditioning has limited benefit for renal, colon cancer patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Stem cell transplantation with low-intensity conditioning has limited efficacy against advanced renal and colon carcinomas. Researchers in Sweden "evaluated whether allogeneic hematopoietic stem...

Pediatric autograft recipients enjoy rapid immune recovery.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Pediatric patients enjoy rapid immune recovery after receiving stem cell autografts. Investigators in Chicago performed a retrospective study to "review the immune reconstitution of children...

HSCs from different sources have different transduction efficiencies.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Results of studies in rhesus macaques have led hematologists with the U.S. National Heart, Lung, and Blood Institute to recommend that "difference in transduction efficiency of HSCs collected from...

Retroviral vector integration into marrow-repopulating cells can be nonrandom.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Study results show, for the first time, that retroviral vector integration into human marrow-repopulating cells can be nonrandom. "Increasing use of hematopoietic stem cells for retroviral...

Results of poll reveal what people really think about genetics.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- The structure of DNA is arguably the most significant discovery of the 20th century - paving the way for disease prediction and treatment, cloning, stem cell research, and many other extraordinary...

"Mini-transplants" offer new hope for older cancer patients.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Patients in their 50s and 60s with blood malignancies, such as leukemia and lymphoma, traditionally have not been eligible for bone marrow or stem cell transplants. Now, new advances allow Fox...

Research: Islet cell transplantation to treat diabetes may lead to cure.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Early data shows that transplanting healthy, insulin-producing islet cells by infusion into the portal vein to the liver enables uncontrolled type 1 diabetic patients to become insulin free, according...

Optimal cryopreservation protocols identified.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Optimal cryopreservation techniques have been identified for umbilical cord blood products. According to recent research published in the journal Cryobiology, "cryopreservation protocols for...

Standard cryopreservation methods may cause extensive damage.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Cryopreservation techniques used for stem cell products may cause extensive damage to umbilical cord blood (UCB). UCB "is an accepted treatment for the reconstitution of bone marrow function...

Company responds to concerns about vaccinia transmission through blood.
May 1, 2003... 2003 MAY 1 - (NewsRx.com & NewsRx.net) -- Bayer Biological Products (BP) announced today that it initiated studies earlier this year to confirm that its manufacturing technologies successfully inactivate vaccinia, the live virus utilized in the...

OX40 ligation prevents graft-versus-host disease.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - OX40 and its ligand play key roles in graft-versus-host reactions after hematopoietic stem cell transplantation, researchers report. OX40 "is expressed on...

Monoclonal IgG may be IVIG alternative for immune thrombocytopenia.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Monoclonal antibodies may be useful for treating immune thrombocytopenia, researchers in Toronto say. "Intravenous immunoglobulin (IVIG) is used to treat...

Vgamma1Vdelta1+ T cells can lyse tumor cells.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Vgamma1Vdelta1 T cells can be induced to lyse leukemia and other malignant cells. "The T-cell subset expressing Vdelta2 paired primarily with Vgamma2 comprises a majority of gammadelta T cells in...

Some prescription medications reduce risk in women.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Some prescription medications can lower the risk of non-Hodgkin lymphoma in women. According to recent research from the Netherlands, "earlier epidemiologic studies have suggested an inverse...

Different PECAM-1 isoforms regulate fundamental elements of hematopoiesis.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Different PECAM-1 isoforms regulate fundamental elements of hematopoiesis. "PECAM-1 (CD31) is a member of immunoglobulin gene superfamily, which is highly expressed on the surface of endothelial...

Automated progenitor cell count assay can improve yield.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- A novel automated hematology assay can improve donor stem cell collection. "Although enumeration of CD34+ cells in the peripheral blood (PB) on the day of apheresis predicts the quantity of those...

Standardized serum-free culture for tumor cells developed.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- An optimized serum-free culture system has been developed for the study of acute lymphoblastic leukemia (ALL) cells In a recent study conducted to "standardize in vitro culture conditions," ALL...

Genetic risk factors identified in mice.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Genetic risk factors for acute myeloid leukemia have been identified in mice. "Inbred CBA/H mice are susceptible to radiation-induced acute myeloid leukemia (r-AML), and C57BL/6 mice are resistant,"...

Subjects have decreased expression of CD95 on CD4+ T-lymphocytes.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Autism may have an immune dysfunction component, and Fas (CD95) was found to be lower on CD4+ helper T cells and higher as a soluble form in blood. According to recent research published in the...

Pten in B cells controls homeostasis and IgG class switch recombination.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- The tumor suppressor Pten has roles in B cells ranging from B cell development and homeostasis to control of autoantibody production. "Pten is a tumor suppressor gene mutated in human cancers. We...

Modern blood vessel measurements test influence of magnetic fields.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Some 2000 years ago, the Chinese first advocated the use of magnetic therapy. In the Middle Ages, Paracelsus (1493-1543), a physician and alchemist, came to the conclusion that since magnets have the...

American Red Cross agrees to revised consent decree.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has announced that the American Red Cross (ARC) has agreed to substantial revisions in its consent decree with the FDA. The revised consent decree includes...

Donor T cell-derived TNF is required for graft-versus-host disease.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Donor T cell-derived TNF is required for graft-versus-host disease after bone marrow transplantation. According to published research from the United States, "Previous studies in murine bone marrow...

Humoral effects on muscle proteolysis delayed.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Burn plasma has a delayed effect on muscle proteolysis in animals. Investigators in Taiwan examined "the effects of plasma from burned rats on skeletal muscle proteolysis." "Major burn injury...

Supplement reduced chemotherapy induced fatigue.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- A new study using the CTF (Chemotherapy Fatigue) nutritional supplement protocol during chemotherapy demonstrated that a properly administered nutritional protocol materially enhanced chemotherapy...

Post-transplant blast crisis can mimic de novo lymphoma.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Blast crisis after stem cell transplantation can mimic de novo lymphoma in some leukemia patients. Researchers in Germany described "the case of a 42-year-old male patient who was diagnosed with a...

Recombinant FVIIa limits dental blood loss in Glanzmann thrombasthenia patients.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Recombinant activated factor VIIa (rFVIIa) can help control blood loss during dental work in Glanzmann thrombasthenia patients. In a recent study, rFVIIa, "combined with local measures of fibrin...

Approval granted to market generic equivalent to Paxil in Spain.
May 8, 2003... 2003 MAY 8 - (NewsRx.com & NewsRx.net) -- Bentley Pharmaceuticals, Inc., (BNT), a technology-based specialty pharmaceutical and drug delivery company with a growing branded and generic product line in Europe, announced that the Spanish Ministry...