Blood Weekly articles from March 2004

Blood Weekly archives from March 2004

Donor T-cell IL-13 output predicts GVHD.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Surprisingly, production of IL-13 by donor T cells can predict the development of acute graft-versus-host reactions. According to a study from England, "Despite the success of human leukocyte...

Early defibrotide treatment effective against hepatic VOD in children.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Early defibrotide (DF) treatment can resolve hepative veno-occlusive disease (VOD) in children. Hepatic VOD is "a complication observed particularly in patients undergoing hematopoietic stem-cell...

Imatinib inhibits hematopoietic progenitor cell proliferation.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Imatinib inhibits the proliferation of hematopoietic progenitor cells. "Imatinib is a novel tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive leukemias and other...

HistoCheck software can help prevent HLA mismatches.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- A novel software program can help prevent HLA mismatches in transplant recipients. "HLA polymorphism is a major barrier for hematopoietic stem-cell and solid organ transplantation," scientists in...

Novel NK cell receptor mediates bone marrow rejection.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- A natural killer (NK) cell receptor has been identified as the mediator of bone marrow allograft rejection. NK cells "mediate bone marrow allograft rejection," scientists in Japan explained....

Novel membrane reactor enhances cord blood cell expansion.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- A novel culture system enhances cord blood cell expansion. "Cord blood hematopoietic stem and progenitor cells (HSPC) represent an important cell source for transplantation of cancer patients after...

Recombinant G-CSF can activate tissue factor pathway.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- The use of rhG-CSF for stem-cell mobilization can activate the prothrombotic TF pathway. "The hypercoagulable state caused by the use of recombinant human granulocyte colony-stimulating factor...

New blood-conserving device has no effect on postoperative anemia.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Although a new blood conservation device significantly reduced iatrogenic blood loss in intensive care unit patients, it did not affect the fall in hemoglobin levels. According to published...

Betula platyphylla var. japonica extract may have anticancer properties.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Animal model shows that Betula platyphylla var. japonica has potential anticancer and antioxidant properties, researchers report. "The antioxidant and anticancer properties of a medicinal plant,...

Procleix Ultrio Assay clinical trials commence.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced that the U.S. clinical trials of the Procleix Ultrio Assay on the Procleix Tigris system have started in San Diego, California, under an investigational new drug. ...

Greece to launch blood donation drive preparing for Olympics.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Faced with a blood shortage, health officials in Greece said February 11, 2004, they are looking for about 50,000 volunteers to donate blood to be used during this year's Olympics and Paralympics. ...

FDA provides marketing clearance for magnesium assay.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Abaxis, Inc., (ABAX), a medical products company manufacturing point-of-care blood analysis systems, announced that it has received U.S. Food and Drug Administration (FDA) market clearance for its...

Fourth phase II trial initiated for new stem cell transplantation drug candidate.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- AnorMED, Inc., (AOM) announced the initiation of its fourth phase II clinical trial to evaluate AMD3100 as a new stem cell transplantation drug candidate for cancer patients. Clinical data to date...

Selective cytokine inhibitors staunch VEGF and interleukin-6 to quell myeloma.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Selective cytokine inhibitors staunch VEGF and interleukin-6 to quell myeloma. "Myeloma cells and human umbilical vein endothelial cells (HUVECs) were cocultured to model in vitro the interactions...

Lamivudine maintains adriamycin intensity in hepatitis B patients with lymphoma.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Lamivudine maintains adriamycin intensity in hepatitis B patients with lymphoma. According to researchers in South Korea, "we investigated the effectiveness of lamivudine to prevent hepatitis flare...

New mathematical algorithms might help diagnose cancer.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Dartmouth researchers have developed an algorithm that might someday be used to analyze blood for diagnostic purposes. Using data from a mass spectrometer, a device that generates a molecular...

Study of adult stem cell reimplantation initiated.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- By harvesting and reimplanting a patient's own stem cells, physicians hope to grow new blood vessels to relieve the disabling chest pain of severely ill cardiac patients. Physicians at Caritas St....

Storing too much iron may put healthy women at higher risk for diabetes.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Higher amounts of iron stores in the blood are associated with an increased risk of type 2 diabetes in healthy women who have no known diabetes risk factors, according to a study in the February 11,...

CDC asking EPA to test suspect environmental contaminant in Sierra Vista.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Investigators from the nation's top disease-fighting agency embarked on a 1-day "field trip" in February to Sierra Vista, Arizona, the site of an alarming cluster of childhood leukemia cases. ...

Company raises $19.5M to advance ion channel drug discovery and development.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Icagen, Inc., has completed a private placement totaling $19.5 million during the fourth quarter of 2003. Proceeds from the financing will be used to continue to advance the company's clinical...

In vitro assays yield data about angiogenesis and myelodysplastic syndromes.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- In vitro assays yield data about angiogenesis and myelodysplastic syndromes. "In myelodysplastic syndromes (MDS), ineffective hematopoiesis and cytopenia may arise either from increased...

Adeno-associated virus encoded for factor IX ameliorates hemophilia B in vivo.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Adeno-associated virus encoded for factor IX ameliorates hemophilia B in vivo. According to recent research from the United States, "previous experiments have demonstrated the stable expression of...

Platelet microparticles contribute to the formation of new blood vessels.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Platelet microparticles contribute to the formation of new blood vessels. According to a study from South Korea, "platelet microparticles (PMP) are endogenous substances generated during the...

Results of Eculizumab trial reported.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Alexion Pharmaceuticals, Inc., (ALXN) announced the publication of its eculizumab clinical trial results in patients with paroxysmal nocturnal hemoglobinuria (PNH) in The New England Journal of...

Clinical trials of Procleix Ultrio Assay begin on Procleix Tigris system.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Gen-Probe Incorporated (GPRO) announced that clinical trials of the Procleix Ultrio Assay, for the simultaneous detection of human immunodeficiency virus 1 (HIV-1), the virus that causes AIDS, hepatitis...

Human embryonic stem cells may promise medical advances.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- New research released at the 2004 American Association for the Advancement of Science (AAAS) Annual Meeting may be a first step toward methods for treating diabetes, osteoarthritis, Parkinson and other...

Human mast cells could be regulated to control VEGF production.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Human mast cells could be regulated to control VEGF production. "Mast cells accumulate in large numbers at angiogenic sites, where they have been shown to express a number of proangiogenic factors,...

Panfungal PCR useful for cerebral aspergillosis diagnosis.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Panfungal PCR can facilitate cerebral aspergillosis diagnosis. Physicians in Japan described their experience treating a "patient with osteosarcoma in whom a brain abscess developed after...

Infectious diseases in the first year of life may protect against ALL.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Study supports the hypothesis that early common infections may play a protective role in the etiology of childhood leukemia, although this effect was not more marked for common acute lymphoblastic...

Massive hyperdiploidy and tetraploidy are rare in AML.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Massive hyperdiploidy and tetraploidy define a prognostically unfavorable cytogenetic group in de novo acute myelocytic leukemia (AML). According to published research from the United States,...

Road traffic exhaust might be involved in childhood leukemia.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Children with more exposure to motor vehicle emissions had higher incidences of leukemia, researchers say. According to a study from Italy, "To assess the effect of road traffic exhaust on the risk...

Late CMV PRP reported after stem-cell transplantation.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- An incidence of late CMV PRP has been reported in a stem-cell transplant recipient. In a case described by physicians in Germany, a "55-year-old man with acute myeloid leukemia in second relapse...

Unrelated cord blood transplantion feasible for adult AML patients.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Unrelated cord blood transplantation (CBT) is feasible for adult AML patients. In a recent study, hematologists in Japan evaluated the outcomes of unrelated CBT "for 18 adult patients with de novo...

API2-MALT1-positive tumors are more aggressive in colorectal lymphoma.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Patients with API2-NALT1-positive tumors should be treated as having more aggressive disease and should be followed longer, researchers say. According to published research from Japan, "The...

Etoposide and thiotepa is an effective preparative regimen for autologous BMT.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Etoposide and thiotepa regimen is effective for patients with relapsed non-Hodgkin's lymphoma having autologous bone marrow transplantation. According to recent research published in the journal...

Reduced-intensity BEAM-alemtuzumab SCT effective.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Reduced-intensity BEAM-alemtuzumab stem-cell transplantation is safe and effective for patients suffering from lymphoproliferative disorders. In a recent study, hematologists in England evaluated...

Medicare law could decrease payments for immunosuppressants.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Recent changes to Medicare law were designed to provide better drug coverage and hold down prices, but some health advocates are worried the shift may hurt one group of patients: those with organ...

Company receives patent for cardiac repair technology.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- GenVec, Inc., (GNVC) announced the issuance of U.S. patent no. 6,673,604, entitled "Muscle Cells and Their Use in Cardiac Repair," which covers transplantable skeletal myoblast compositions (muscle...

Orphan drug designation granted by FDA for BCX-1777.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- BioCryst Pharmaceuticals, Inc., (BCRX) announced that the U.S. Food and Drug Administration (FDA) granted orphan drug status to BCX-1777, the company's purine nucleoside phosphorylase (PNP) inhibitor...

Company announces positive results in phase I dental study.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Isolagen, Inc., (ILE), a biopharmaceutical company specializing in the development and commercialization of autologous (a patient's own) cellular therapy for hard and soft tissue regeneration (the...

Patent granted for EradicAide technology to diagnose, prevent, treat AIDS.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Adventrx Pharmaceuticals (AVRX) announced that its collaborators at the University of Texas M.D. Anderson Cancer Center have been issued United States Patent number 6,656,471 entitled "HIV-specific...

Brazilian ex-soccer players may have spread hepatitis C with shared needles.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Brazilian ex-soccer players may have spread hepatitis C with shared needles. According to recent research from Brazil, "in order to evaluate the significance of injecting vitamins complexes and...

Phase I study of ABX-PTH initiated.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Abgenix, Inc., (ABGX) announced that the company has started a phase I clinical trial of ABX-PTH, a fully human monoclonal antibody generated by Abgenix's technology platform that targets and...

Bone marrow stem cells have highly variable mitochondrial DNA.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Bone marrow (BM) stem cells have highly heterogenous mitochondrial DNA (mtDNA) patterns. According to recent research from the United States, somatic mtDNA mutations "accumulate with age in...

Campaign to make California stem cell capital under way.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- A coalition of wealthy patient advocates, eminent scientists and Hollywood executives have launched a well-funded campaign to make California a hub for human embryonic stem cell research even as tepid...

Cardiac potential of adult stem cells reviewed.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- The cardiac potential of adult stem cells has been reviewed. "Adult cardiac muscle is unable to repair itself following severe disease or injury," scientists in the United States explained....

Effects of cdk-inhibitors on stem-cell quiescence clarified.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- The effects of cdk-inhibitors on stem-cell quiescence have been clarified. "Prolonged quiescence of hematopoietic stem cells has been proposed to support durable hematopoiesis through clonal...

Electroporation augments the transfection of marrow stromal cells.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Electroporation augments the transfection of marrow stromal cells. "Human marrow stromal cells (hMSCs) are an attractive source of adult stem cells for autologous cell and gene therapy. To transfect...

HemoPDB provides comprehensive hematopoietic promoter info.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- The "HemoPDB" software provides extensive genetic information on hematopoietic cells. "Hematopoiesis describes the process of the normal formation and development of blood cells, involving both...

Immune response makes stem cells transduced by lentiviral vectors disappear.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Immune response makes stem cells transduced by lentiviral vectors disappear. "Lentiviral vectors are increasingly being used for transferring genes into hematopoietic stem cells (HSCs) due to their...

Meropenem prophylaxis reduces febrile episodes in stem cell transplant patients.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Meropenem prophylaxis reduces febrile episodes in stem cell transplant patients. According to recent research published in the journal Bone Marrow Transplantation, "in the present study, we analyze...

PU.1 supports proliferation of immature erythroid progenitors.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- The transcription factor PU.1 is needed for the efficient proliferation of immature erythroid progenitor cells. "Despite normal levels of erythropoiesis in PU.1(-/-) embryos, PU.1(-/-) fetal...

TRAIL regulates erythroid maturation via ERK signaling.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- TRAIL regulates the maturation of erythroid cells through ERK signaling. According to recent research from Italy, "In order to investigate the biologic activity of tumor necrosis factor-related...

Ideal body weight should be used to determine stem-cell allograft dose.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Ideal body weight should be used to determine allogeneic stem-cell graft dose. "The number of CD34+ cells infused influences hematologic recovery after transplantation," scientists in Chicago...

RIC SCT feasible for patients with advanced solid tumors.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- RIC allo-SCT is feasible for solid cancer patients with advanced and treatment-resistant tumors. In a "prospective multicenter program," scientists in France "investigated allogeneic stem cell...

Surprising patterns of stem-cell engraftment identified.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- A study of the dynamics of post-transplant stem-cell engraftment has yielded surprising results. "To reveal the early events and dynamics of hematopoietic reconstitution in living animals in...

Treosulfan-fludarabine conditioning regimen safe and effective.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- A treosulfan-fludarabine conditioning regimen is safe and effective for bone marrow allograft recipients. According to scientists in Germany, "New conditioning regimens are being explored to reduce...

Cancer patients are at high risk for recurrent thromboembolism.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Using low-molecular-weight heparins for initial treatment and long-term anticoagulation in cancer patients with venous thrombosis seems promising, researchers report. "In contrast with the paucity...

Prior thrombolic events and thrombophilias warrant heparin during pregnancy.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Prior thrombolic events and thrombophilias warrant heparin during pregnancy. "Pregnancy and puerperium are well-known risk factors for venous thromboembolism, but the actual incidence of the disease...

Company announces Galileo submission to FDA.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Immucor, Inc., (BLUD), a provider of automated instrument-reagent systems to the blood transfusion industry, announced that it has submitted the 510(k) premarket notification submission for its Galileo...

Ethicists say troubling living donor cases need guidelines.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Medical ethicists are warning that guidelines are needed to cover instances in which family members want to donate organs for transplant from living but comatose relatives who never gave consent. ...

Histology stabilizes in HCV-recurrent living donor liver transplant recipients.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- Histology stabilizes in HCV-recurrent living donor liver transplant recipients. "Recurrence of hepatitis C virus (HCV) after liver transplantation (LT) is a universal phenomenon. Recent reports have...

Remaining patent issued for the CryoSeal platform products.
March 4, 2004... 2004 MAR 4 - (NewsRx.com & NewsRx.net) -- ThermoGenesis Corp. (KOOL) has received the tenth patent that completes the portfolio protecting the CryoSeal platform products that use medical devices and companion single-use sterile disposables to...

Autologous fibrin glue useful for maxillofacial surgery.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- A novel autologous fibrin glue can reduce transfusion needs in maxillofacial surgery patients. Scientists in Denmark developed "a method for the preparation of autologous fibrin glue with platelet...

Rituximab effective against post-SCT autoimmune hemolytic anemia.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Rituximab therapy can resolve AIHA in stem-cell graft recipients. According to published research from Japan, a "30-year-old Japanese woman who underwent nonmyeloablative stem-cell transplantation...

Stem-cell transplantation can prevent lysosomal storage disease-induced CVD.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Stem-cell transplantation can prevent cardiovascular dysfunction associated with lysosomal storage disease. "Cardiovascular manifestations of lysosomal storage disease (LSD) are a significant...

Novel DNA extraction method enables HIV diagnosis via dried blood.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- A novel DNA extraction technique enables diagnosis of vertical HIV transmission from dried blood specimens. "Dried blood spots (DBS) on filter paper facilitate the collection, transport, and...

SCT with voriconazole treatment feasible for AML with pulmonary aspergillosis.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Stem-cell transplantation with extended voriconazole therapy is safe and effective for acute myeloid leukemia (AML) patients with pulmonary aspergillosis. According to recent research published...

Minisequencing useful for SNP analysis.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- A minisequencing assay is useful for single-nucleotide polymorphism (SNP) genotyping in stem-cell graft recipients. According to recent research from Sweden, SNPs "have the potential to be...

Metabolomics company awarded biomarker study collaboration.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Metabolon, Inc., announced its collaboration with Massachusetts General Hospital and the University of Pittsburgh (Pennsylvania) School of Medicine on a new biomarker study funded by The ALS...

Sepsis drug also protects brain cells.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- A compound currently used to treat patients with severe sepsis also protects brain cells in an unexpected way, say researchers at the University of Rochester Medical Center. Doctors currently use...

Therapeutic company files five patent infringement lawsuits.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- PharmaStem Therapeutics, Inc., has filed a lawsuit for patent infringement, in the United States District Court, Northern District of California, against five companies active in umbilical cord blood...

Harvard study says aspirin may lower risk of Hodgkin disease.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Scientists have found a hint that regular aspirin use might lower the risk of Hodgkin lymphoma, but more research is needed to prove it. Even if the link is real, Hodgkin is too rare a cancer to...

Amidox inhibits ribonucleotide reductase in human leukemia cells.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Amidox is cytotoxic against human HL-60 promyelocytic leukemia cells. According to published research from Austria, "Amidox, a new polyhydroxy-substituted benzoic acid derivative, is a potent...

U.S. Food and Drug Administration approves clinical trial for MethLock.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has approved a clinical trial for MethLock, a catheter lock solution developed by Ash Access Technology, Inc., a Lafayette, Indiana, company focused on vascular...

Chemical that turns mouse stem cells into heart muscles discovered.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- A group of researchers from the Skaggs Institute for Chemical Biology at the Scripps Research Institute and from the Genomics Institute of the Novartis Research Foundation (GNF) has identified a small...

Stem cell "ribbon" found in adult human brain.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Researchers have discovered a new source of neural stem cells in the adult brain. Arturo Alvarez-Buylla and colleagues studied brain tissue samples taken from live patients undergoing brain surgery...

CNS tumor survivors have lower quality of life than ALL survivors.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Researchers present study data about quality of life of children who survived acute lymphoblastic leukemia (ALL) or central nervous system (CNS) tumors. "Survivors of childhood cancer are at risk...

Lack of cytogenetic response after imatinib treatment predicts relapse.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Researchers in Ireland have discovered that leukemia patients who do not have a major cytogenetic response within 6 months of imatinib mesylate treatment have a higher incidence of relapse. "We...

Blood test could avoid inappropriate use of antibiotics for respiratory infections.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- A rapid blood test to help distinguish between bacterial and other (predominantly viral) infections could substantially reduce the inappropriate use of antibiotics for common infections, conclude...

Leukemia panel will meet once more in northern Nevada town.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- An expert panel involved in extensive studies of a childhood leukemia cluster in this rural northern Nevada town presents a final report February 16, 2004, and no conclusive answers are expected. ...

Fetal mouse brain cells self-destruct when maternal folate levels are deficient.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Fetal mouse brain cells self-destruct when maternal folate levels are deficient. According to recent research from the United States, "in mice and rats, maternal dietary choline intake during late...

Hemophilia treatment developer reports yearly loss of $1.28 per share.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Avigen, Inc., (AVGN) reported financial results for the year ended December 31, 2003. At year end, Avigen had approximately $99 million in cash, cash equivalents, available-for-sale securities and...

Company presents model for a new therapeutic vaccination strategy against HIV.
March 11, 2004... 2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Lipid Sciences, Inc., (LIPD) announced that a poster exhibited at the Conference on Retroviruses and Opportunistic Infections in San Francisco, California, illustrates that a delipidated retrovirus...