Blood Weekly articles from January 2004

Blood Weekly archives from January 2004

Retrograde perfusion improves lung graft performance in pigs.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Retrograde perfusion improves the performance of donor lung grafts in a porcine lung transplantation model. In a recent study from California, "Transpulmonary thermodilution was used to evaluate...

Cyclophosphamide treatment reduces serum cyclosporine A levels.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- CY treatment significantly reduces serum CsA levels in stem-cell graft recipients. In a recent study, scientists in Japan "retrospectively analyzed the factors that affect serum cyclosporine (CsA)...

STAT5 required for tolerance in mice.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Contrary to conventional wisdom, the transcription factor STAT5 plays a key role in murine immune tolerance. According to recent research from the United States, "STAT5 has previously been reported...

Unrelated stem-cell transplantation can be effective for MM patients.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Stem-cell transplantation using grafts from unrelated donors is effective and relatively safe for multiple myeloma patients, especially for those who receive pretransplant CAMPATH treatment. ...

Lineage-primed HSCs retain long-term repopulation potential.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Lineage-primed hematopoietic cells retain long-term, multilineage repopulation potential. "Single cell PCR studies showed that hematopoietic stem cells (HSCs) express a variety of...

Combination CTL/endothelial cell test identifies GVHD.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A novel assay accurately identifies graft-versus-host reactions in stem-cell transplant recipients. "Cytotoxic T lymphocytes (CTLs) are important effector cells of graft-versus-host disease (GVHD)...

Gleevec shows promise in treating another form of leukemia.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Gleevec, which has produced striking results in patients with chronic myeloid leukemia (CML), is now demonstrating encouraging benefits in treating a different blood cancer, a type of acute lymphocytic...

TRAF6 has many essential functions spanning immune, bone, and nerve functions.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- TRAF6 has many essential functions spanning immune, bone, endocrine, and nerve functions. "Tumor necrosis factor (TNF) receptor associated factor 6 (TRAF6) is a crucial signaling molecule...

Wasp venom immunotherapy may work by increasing allergic patient CD86, IL-10.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Wasp venom immunotherapy may work by increasing CD86 and IL-10 in allergic patients. According to published research from Japan, "several studies have provided evidence that activation of...

FGF-2 levels are higher in serum and present in CSF of ALS patients.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Fibroblast growth factor 2 (FGF-2) levels are higher in serum and present in CSF of amyotrophic lateral sclerosis (ALS) patients; levels do not correspond with a specific disease state. "Lack of...

Late-life anemia identifies people at risk for mortality and hospitalization.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Anemia is common in old age and has been shown to affect the physical function of elderly adults. Researchers from Wake Forest University School of Medicine, Winston-Salem, North Carolina,...

Anaphylaxis is a dangerous risk in surgical patients undergoing anesthesia.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Anaphylaxis is one of the most dangerous risks in surgical patients undergoing anesthesia; muscle relaxants or latex are the most common triggers. "Anesthesiologists use a myriad of drugs during the...

Bone marrow endothelial cells produce some SDF-1 in culture, also CXCR4 in vivo.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Bone marrow endothelial cells (BMECs) produce some stromal cell-derived factor-1 (SDF-1) in culture and will also produce CXCR4 in vivo. According to a study from South Korea, "this study...

JAML protein expressed in leukemia, leukocytes enhances adhesion to endothelials.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Junctional adhesion molecule-like (JAML) protein expressed in leukemia and leukocytes is at plasma membrane cell contacts and enhances adhesion to endothelials; it may be involved in transmigration. ...

The immunoproteasome produces better MHC antigens than constitutive proteasome.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The immunoproteasome produces better MHC antigens than the constitutive proteasome can. "Intracellular proteins are degraded largely by proteasomes. In cells stimulated with IFNgamma, the active...

CD8+ T cells, including CMV-specific ones, are altered in Wegener granulomatosis.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- All CD8+ T cells, including those specific for CMV, have altered phenotypes in Wegener granulomatosis (WG). According to recent research from Germany, "WG is an autoimmune disease of as yet unknown...

American Society of Hematology honors prominent researchers.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The American Society of Hematology has announced the winners of two of the Society's highest honors. The William Dameshek Prize, endowed by the late Dr. William Dameshek, a past president of the...

Early research shows possible platelet preservation of 8 days or more.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Early findings indicate that it may be possible to augment platelet preservation from 5 days to 8 days or more, according to Sherrill Slichter, MD, Puget Sound Blood Center executive vice president of...

Research seeks ways to transfer donor immunity to pathogens to recipient.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Bone marrow transplants are inherently dangerous and are associated with many potentially fatal health risks. To make room for donor cells in a recipient's bones, conditioning of the patient prior to a...

Breast cancer risk from antibiotics may be due to altered immunity, microflora.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Breast cancer may develop with sustained antibiotic use due to influence on immunity as well as reduced intestinal microflora carcinogen processing. According to recent research published in the...

High-dose pre-SCT vinorelbine-paclitaxel regimen safe and effective.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A high-dose VNB-PTX regimen is safe and effective for breast cancer patients prior to stem-cell transplantation. In a recent study, scientists in Italy evaluated "the safety, activity and...

In aging model of burn injury, macrophage number is same, MCP-1 lower initially.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Macrophages infiltrate burned skin at the same levels, but produce less monocyte chemoattractant protein-1 (MCP-1) initially in an animal model for aging. "Clinical observations and laboratory...

Mesenchymal progenitor cells may serve as gene delivery systems.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Unlike hematopoietic (blood forming) stem cells, bone marrow-derived mesenchymal progenitor cells, or stem cells (MSC), can be intravenously injected into patients with leukemias and solid tumors...

Post-SCT respiratory virus infections common but transient.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Respiratory virus (RV) infections are common, but usually mild and transient in cancer patients who undergo stem-cell transplantation. According to recent research from the United States,...

Fibrin mobility might be useful for protein and gene trafficing.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Fibrin mobility might be useful for protein and gene trafficing. "Recent studies have shown that fibrin promotes epidermal regeneration in vitro and maintains the stem cell population after...

Red blood cells have the capacity to increase survival, expansion of T cells.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Red blood cells (RBCs) have the capacity to increase survival, expansion of T cells; CD58/LFA-3 and heme related compounds do not appear to be involved. "RBCs are known to modulate T cell...

Red Cross hopes to start testing blood supply for parasite disease.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The American Red Cross within a few years hopes to start screening blood donations for Chagas disease, which can lie dormant for decades before sometimes causing fatal heart complications. The...

Transfusion-transmitted CMV explored in mouse model.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Transfusion-transmitted cytomegalovirus (TT-CMV) infections occur in up to 3% of immunocompromised patients, despite the use of CMV seronegative (antibody negative) and filtered blood components. ...

Low iron levels associate with hair loss in women.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Low iron levels associate with hair loss in women. "Alopecia in women is a common problem, and conflicting observational data have failed to determine whether an association exists between alopecia...

The wide array of complement-related therapeutics have very different features.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The wide array of complement-related therapeutics have very different features and uses. "Complement (C) performs vital roles in immune surveillance, from killing of bacteria to generation of an...

Permanent carotid diverter product is implanted for the first time in a human.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- MindGuard, Ltd., a privately held developer of stroke-prevention medical devices, announced that its Diverter flagship product was implanted in a human on October 1, 2003. The approach, the...

Pyrogens induce increases in hypothalamic beta-endorphins that trigger fever.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Pyrogens induce increases in hypothalamic beta-endorphins that trigger fever; opioid receptor antagonist buprenorphine attenuates it in an animal model. According to recent research from Taiwan, "at...

Cellular cross-talk modulates angiogenesis in the murine gut.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Cellular cross-talk modulates angiogenesis in the murine gut. According to a study from the United States, "zymogenic cells (ZCs), acid-producing parietal cells (PCs), and mucus-secreting pit cells...

Gene variation link examined in bone marrow transplant.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A common genetic variation appears to reduce the risk of a serious complication after a bone marrow transplant, new research shows. People who had the gene variation were half as likely as other...

A new assay screens for total hepatitis C virus core antigen in blood donors.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A new assay screens for total hepatitis C virus core antigen in blood donors. "Recent studies have shown that total hepatitis C virus (HCV) core antigen, both free and antibody bound, is an accurate...

Healthy humans can also make anti-factor VIII antibodies with CD4+ T cells.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Healthy humans can also make anti-factor VIII antibodies with CD4+ T cells; some secrete cytokines, too. According to published research from the United States, "hemophilia A patients treated with...

Joint TRA-418 receptor antagonist, agonist function increase antiplatelet action.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Joint TRA-418 functions of TP-receptor antagonist, IP-receptor agonist make it a better antiplatelet agent. "{4-[2-(1,1-Diphenylethylsulfanyl)-ethyl]-3,4-dihydro-2H-benzo[1,4]oxazin-8-yloxy}-acetic...

Platelet binding by von Willebrand factor heightened in neonates.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The platelet-binding activity of von Willebrand factor (VWF) is heightened in neonates. According to recent research from Canada, VWF "is important in platelet adhesion and shear-dependent platelet...

Albumin has innate immunity function, inhibits B. dermatitidis yeast growth.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Albumin has an innate immunity function, inhibiting Blastomyces dermatitidis yeast growth. "In this study, we found that serum inhibitory activity against Blastomyces dermatitidis was principally...

Beryllium dermatitis may contribute to pulmonary, noncutaneous reactions.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Beryllium dermatitis can occur by occupational exposure; may contribute to pulmonary and noncutaneous reactions. According to a study from the United States, "chronic beryllium disease is a...

IL-15Ralpha needed for Ly-49 induction on NK cell progenitors.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The IL-15Ralpha-chain is needed for efficient induction of Ly-49 receptors on natural killer (NK) cell progenitors. "IL-15Ralpha-deficient (IL-15Ralpha(-/-)) mice lack NK cells," immunologists in...

Maternal antibodies contribute to a hematologic disorder in newborn infants.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Maternal antibodies contribute to a hematologic disorder in newborn infants. "From 1991 to 2000, amongst 23,886 full-term healthy Chinese babies delivered at our hospital, 2615 babies developed...

Umbilical cord blood cells respond weakly to TLR-3 and -4 ligands.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Umbilical cord blood cells respond weakly to toll-like receptor (TLR)-3 and -4 ligands, which may help explain neonates' high susceptibility to infection. According to published research from...

Canadian biotech adds third drug candidate to its immunosuppressive pipeline.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Isotechnika, Inc., (ISA) announced the addition of a third drug candidate to its immunosuppressive drug pipeline. The new drug candidate, TKB662, is designed to address the two major challenges in...

H. ducreyi can give pustule or resolution regardless of phagocytosis level.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Humans challenged with Haemophilus ducreyi have pustule or resolution response regardless of phagocytic activity level. According to recent research published in the journal Infection and Immunity,...

Molecular blood test enables rapid and accurate fungal infection diagnosis.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A novel molecular blood test enables rapid and accurate detection of the fungal pathogens Candida albicans and Aspergillus fumigatus. In the journal Diagnostic Microbiology and Infectious Disease,...

Ocular toxoplasmosis can be treated to eliminate deterioration of vision.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Ocular toxoplasmosis (OT) can be treated to eliminate deterioration of vision. "The protozoan parasite Toxoplasma gondii is an important cause of ocular disease," scientists writing in the journal...

Fibrillary noncongophilic deposits occur in fibrillary glomerulonephritis, lupus.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Congo red negative amyloid-type fibrils are seen to be in kidney of patients with fibrillary glomerulonephritis (FGN) and lupus, but can also sometimes be present in many organs. According to...

AP23464 is effective in Gleevec-resistant leukemia cells.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Ariad Pharmaceuticals, Inc., (ARIA) announced, for the first time, that AP23464, its lead product candidate to treat certain forms of leukemia, is highly effective in blocking the growth of leukemia...

First patient enters pivotal phase II study for clofarabine.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Bioenvision (BIV) announced the first patient has received treatment in a pivotal European phase II pediatric study in acute lymphoblastic leukemia (ALL), with its lead compound, clofarabine. The...

Higher dose of Gleevec leads to increased remission in CML patients.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Twice the standard daily dose of Gleevec results in a significantly higher response rate in treatment of chronic myeloid leukemia (CML), according to researchers at the University of Texas M.D. Anderson...

New assay will help diagnose, monitor therapy for cancer patients.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- At the American Society of Hematology meeting in San Diego, California, Cancer Genetics, Inc., (CGI) launched a new, highly sensitive DNA FISH assay to help diagnose and monitor therapy of chronic...

Newly identified genes may help predict outcome in childhood leukemia.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The measurement of new genes at diagnosis in children with acute lymphoblastic leukemia (ALL), discovered through new technologies from the Human Genome Project, may be highly predictive of therapeutic...

PTEN expression in leukemic T cells leads to reduced proliferation.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Researchers report that PTEN expression in leukemic T cells leads to reduced proliferation. According to recent research from the United States, "The balance of activities between the proto-oncogene...

Tipifarnib shows activity in previously untreated poor-risk AML and MDS.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A phase II trial of a non-peptidomimetic agent, tipifarnib, shows that the drug has activity in previously untreated poor-risk acute myeloid leukemia (AML) and myelodysplastic syndrome, with a...

Chilean survival rates after liver transplantation compare with other nations.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Chilean survival rates after liver transplantation compare with other nations. According to a study from Chile, "acute liver failure (ALF) is a severe, life-threatening condition associated with a...

New drugs would help graft recipients with recurrent hepatitis C infection.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- New drugs would help liver graft recipients with recurrent hepatitis C infection. "Treatment responses are lower in immune compromised patients such as those with hepatitis C virus (HCV) disease...

Adding rituximab to chemotherapy does not influence response in older patients.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Adding rituximab to the standard chemotherapy regimen for lymphoma patients, CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), does not significantly increase survival in older patients...

Foundation to provide $12.8 million for mantle cell research.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The Lymphoma Research Foundation (LRF) will award $12.8 million in research funding to help find a cure for mantle cell lymphoma, one of the rarer forms of the disease. Eighteen research grants...

CIITA ubiquitination increases assembly of factors and MHC-II transcription.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Class II transactivator (CIITA) ubiquitination increases assembly of factors, promoter, and thus MHC-II transcription; eukaryotes do have ubiquitination-related transcription control. "Although...

High-dose chemotherapy more beneficial for MM patients with high-risk features.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The beneficial effects of high-dose chemotherapy (HDT) are greater in multiple myeloma (MM) patients with high-risk features than in patients without such poor prognostic indicators, researchers say....

Imatinib mesylate suppresses MM tumor cell proliferation in vitro.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- STI571 suppreses the proliferation of multiple myeloma (MM) tumor cells in vitro. According to recent research from Spain, "c-Kit has been shown to be mutated in several types of tumors, and its...

MM antigen HM1.24 loaded in adeno-associated virus produces anticancer T cells.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Synthetic multiple myeloma self-antigen HM1.24 packaged in adeno-associated virus can be loaded in dendritic cells; these induce a strong cytotoxic T cell response against the cancer. According to...

Behavior of neural stem cells during MS characterized.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The behavior of neural stem cells has been characterized in a murine model of multiple sclerosis. According to scientists in California, "In multiple sclerosis, the central nervous system is...

New drug treats anemia in patients with MDS.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Effective management for myelodysplastic syndrome (MDS) is limited, but a study presented by researchers at the Arizona Cancer Center, Tucson, indicates that a new drug, CC5013, may have unprecedented...

Signal patterns that control phagocytosis are important in CNS immunity, repair.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Signal patterns that control phagocytosis are important in central nervous system (CNS) immunity and repair. According to published research from Wales, "a full innate immune system (e.g....

Cytokine signals cooperate in the presence of retinoic acid receptor alpha.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Cytokine signals cooperate in the presence of retinoic acid receptor alpha. "Acute promyelocytic leukemia (APL) is associated with chromosomal translocations involving retinoic acid receptor alpha...

Company secures new patent on creation of knockout mice.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Lexicon Genetics, Inc., (LEXG) announced the recent issuance of U.S. patent no. 6,653,113 (the "113 patent") entitled "High Efficiency Gene Targeting in Mouse Embryonic Stem Cells." The newly...

Ronco named to scientific advisory board at medical device firm.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Aethlon Medical, Inc., (AEMD) announced that Claudio Ronco, MD, has been appointed to the company's Science Advisory Board. Ronco is the director of the Dialysis and Renal Transplantation Programs...

ProMetic in-licenses its plasma separation technology.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Hemosol, Inc., (HMSL) announced that it has forged the principle terms of a strategic alliance with ProMetic Biosciences, Ltd., a wholly owned subsidiary of ProMetic Life Sciences, Inc., (PLI) that will...

Aspirin use safe and effective in patients with abnormal red cell counts.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The use of low-dose aspirin significantly reduces the risk of thrombosis in patients with polycythemia vera, an abnormal increase in blood cells resulting from excess production by the bone marrow,...

ATRA/As[subscript]2O[subscript]3 combination yields high-quality clinical/molecular remission.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- All-trans retinoic acid (ATRA, found in vitamin A) and arsenic trioxide (As[subscript]2O[subscript]3, an inorganic chemical compound) have separately proved very effective in treating acute...

Chelidonium majus CM-Ala may protect against radiation exposure.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Chelidonium majus CM-Ala allows animal model to recover from radiation exposure and is prophylactically radioprotective. "We earlier reported that CM-Ala isolated from Chelidonium majus had...

More studies of HCV-positive kidney donations and survival are needed.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- More studies of HCV-positive kidney donations and survival are needed. According to research from Italy, "hepatitis C Virus (HCV) infection is the most important cause of liver disease after renal...

Scientists create sperm from stem cells.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Scientists say they have turned mouse embryonic stem cells into primitive sperm cells, and then used the sperm cells to fertilize eggs. The team's work could offer insights into male infertility and...

Thromboembolism after ovarian stimulation can be managed with drugs or surgery.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Thromboembolism after ovarian stimulation can be managed with drugs or surgery. According to recent research published in the journal Human Reproduction, "the current literature was reviewed in...

TNF etanercept can induce lupus erythematosus, autoimmune symptoms.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Tumor necrosis factor antagonist (TNF) etanercept can bring on systemic lupus erythematosus (SLE), autoimmune symptoms. According to a study from England, "TNF is a proinflammatory cytokine with a...

Anaplasma marginale varies membrane antigens; may explain disease cyclicity.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Anaplasma marginale varies outer membrane proteins; this could explain cyclic disease in host. According to a study from the United States, "vector-borne bacterial pathogens persist in the...

Anticancer compound may offer new treatment for sickle cell anemia.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) announced that results of a clinical study suggest that the investigational anticancer compound Dacogen (decitabine for injection) is active in treating sickle cell anemia. ...

Company announces roll-out of its HALO hemotoxicity test kit platform.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- HemoGenix has now made available its proprietary HALO technology as a kit for individual researchers at universities, hospitals, and clinics, and other institutes worldwide for use in their own...

New method of identifying and isolating stem cells developed.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Researchers at the Howard Hughes Medical Institute at the Rockefeller University have discovered a new method to track and isolate elusive stem cells. The new animal model they developed was...

Mesenchymal stem cell autografts induce vocal fold regeneration in animals.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Autologous MSCs have been used to induce vocal fold regeneration in a canine model. In a recent study, scientists from Japan sought "to regenerate the injured vocal fold by means of selective...

Therapeutic cloning generates cloned, compatible stem cells in bovine model.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Therapeutic cloning, also known as somatic cell nuclear transfer, which is used in experimental tissue and organ generation, has recently been explored as a possible treatment for a wide range of...

BG/BCNU induces in vivo selection of MGMT(P140K) lentivirus-transduced stem cells.
January 1, 2004... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- BG/BCNU treatment induces selection of MGMT(P140K) lentivirus-transduced stem cells in mice. "Infusion of transduced hematopoietic stem cells into nonmyeloablated hosts results in ineffective in...