Blood Weekly articles from January 2003

Blood Weekly archives from January 2003

Heat treatment doesn't inactivate parvovirus B19.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Parvovirus B19 contamination in some blood products can survive processing, researchers in Germany warn. "Human parvovirus B19 (B19) DNA can be frequently...

Growth factors can optimize hepatocyte development.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Japan have developed a system to increase the epithelial liver cell yield from bone marrow stem cell cultures. "Recent studies have revealed...

Drug that boosts blood cell production reduces transfusions in critically ill.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Critically ill patients who received weekly administration of recombinant human erythropoietin (rHuEPO, which stimulates the body to produce new red blood cells) lowered their likelihood of receiving a...

Fluconazole effective as fungal infection prophylaxis.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The triazole antifungal agent fluconazole can be used to prevent fungal infections in stem cell recipients, researchers in Singapore report. "Over the past...

Reduced-intensity conditioning lowers viral respiratory infection mortality.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Reduced-intensity conditioning for stem cell transplantation lowers the mortality rate of posttransplant respiratory virus infections, according to researchers...

Urokinase can improve cord blood stem cell yield.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in South Korea have identified a novel way to improve hematopoietic progenitor cell harvests from umbilical cord blood. Young-Ho Lee and...

Gene transfer improves erythroid development in Diamond-Blackfan anemia.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Researchers in Sweden believe gene therapy may prove useful for patients with the congenital bone marrow failure syndrome, Diamond-Blackfan anemia (DBA). DBA is "characterized by a specific...

FDA clears COBAS Ampliscreen system.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Roche Diagnostics, based in Indianapolis, has announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance of the company's COBAS AmpliScreen System. The COBAS...

More families banking blood cells from umbilical cords.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- The insurance policy Gillian and Kevin Duffy took out on their newborn son is bathed in liquid nitrogen and stored in a special freezer at -384 degrees F. Minutes after Kieran was born in April at...

Blood transfusion linked to liver cancer risk in a high-endemic area of Japan.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Recent study findings suggest a history of blood transfusion increases risk of developing liver cancer in the Fukuoka prefecture, Japan. "The high prevalence of liver cancer in Japan may be owing...

Study supports benefit of lentiviral-vectored gene therapy.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- "Fanconi anemia (FA) is an inherited cancer susceptibility syndrome caused by mutations in a DNA repair pathway including at least six genes (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG). The...

Blood transfusion-focused biotech company reports third quarter results.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- V.I. Technologies (Vitex), Inc., (VITX), a biotechnology company dedicated to developing products that improve the safety of the transfusion blood supply, announced its financial results for the third...

Second stem cell transplant confers longer remission.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- At a presentation at the 44th annual meeting of the American Society of Hematology in Philadelphia, Dr. Michele Cavo reported on the "Bologna 96" clinical trial of single vs. double autotransplants for...

Licensing agreement signed for generic urokinase.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Microbix Biosystems, Inc., (TSX) announced that it has signed an agreement for the worldwide rights to its lead biotherapeutic drug ThromboClear, a generic version of Abbott Laboratories' urokinase...

Coriell Institute ships first unit for transplantation.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- The Coriell Institute for Medical Research's New Jersey Cord Blood Bank (NJCBB) has been approved as a National Marrow Donor Program member and it has recently shipped its first umbilical cord blood...

Cytokine gene mutations linked to high graft-versus-host disease risk.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Sweden have identified several genetic risk factors for graft-versus-host reactions in stem cell graft recipients. "Certain cytokine gene...

Posttranslant delirium common in cancer patients.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Cancer patients treated with stem cell grafts often have delirious episodes after transplantation, researchers in the United States warn. "Delirium is...

Reverse seroconversion of HBV not uncommon among HBsAG+ recipients.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- According to a study from Japan, "Hepatitis B virus (HBV) reactivation in patients previously positive for hepatitis B surface antibody (HBsAb), so-called reverse seroconversion, has been considered to...

Research continues into anionic phospholipids.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Peregrine Pharmaceuticals (PPHM) announced that researchers at the University of Texas Southwestern Medical Center at Dallas (UT Southwestern) have further characterized and defined anionic...

JDRF launches center for islet transplantation at Washington University.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- The Juvenile Diabetes Research Foundation International (JDRF) announced the launch of the $2.9 million JDRF-Danielle DeNight Center for Islet Transplantation at Washington University School of Medicine...

New Lovenox data presented at hematology gathering.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Aventis has announced that new data supporting the efficacy and safety of Lovenox (enoxaparin sodium injection) for the prophylaxis and treatment of venous thromboembolic disease (VTE) was presented at...

Death in Maryland likely related to blood transfusion.
January 2, 2003... 2003 JAN 2 - (NewsRx.com & NewsRx.net) -- A Maryland woman's death from West Nile virus was probably related to a blood transfusion she received, health officials say. The national Centers for Disease Control and Prevention has listed the...

Transduction with Fas ligand improves bone marrow engraftment.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have developed a novel method for preventing bone marrow graft rejection. "Fas-mediated apoptosis is a major physiologic...

Peripheral blood stem cell grafts may be linked to lower quality of life.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Peripheral blood-derived stem cell grafts may reduce cancer patients' quality of life (QOL), researchers in Brazil warn. QOL "is an important clinical...

Myeloablation enhances engraftment of transduced murine hematopoietic cells.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Researchers in Spain report that "[m]yeloablation enhances engraftment of transduced murine hematopoietic cells, but does not influence long-term expression of the transgene." "To investigate to...

Reduced DMSO levels in peripheral blood concentrate improves cell viability.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Reducing dimethyl sulfoxide (DMSO) levels in peripheral blood stem cell products can improve the outcome of autologous transplantation, researchers in Norway...

Granulocyte colony-stimulating factor can hasten pediatric recovery.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Granulocyte colony-stimulating factor (G-CSF) treatment can enhance hematological recovery in pediatric stem cell transplant recipients, researchers in Italy...

Human leukocyte antigen alleles affect graft-versus-host disease risk.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Sweden have identified several factors affecting the risk of graft-versus-host reactions after hematopoietic stem cell transplantation (HSCT)....

Growth factor antagonists may reverse course of hematologic cancer.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Antagonists that block the activity of angiogenic growth factors could be key to treating acute myeloid leukemia. Researchers at Children's Hospital...

PDI signs sales agreement for new theranostic test.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- PDI, Inc., (PDII) a commercial sales and marketing partner to the biopharmaceutical and medical devices and diagnostics industries, and PharmaNetics, Inc., (PHAR) a theranostic management company...

Sulzer, ITC to comarket ProTime anticoagulation system.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Sulzer Carbomedics, Inc., (Carbomedics) has announced an agreement with Thoratec's International Technidyne Division (ITC) to comarket ITC's ProTime Microcoagulation System to cardiologists and...

Clinical safety and efficacy trial of rhATIII begins.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- GTC Biotherapeutics, Inc., (GTCB) announced the initiation of a safety and efficacy study of its recombinant human antithrombin III (rhATIII) for the treatment of patients with a hereditary deficiency...

ThermoGenesis names Kevin Simpson president and COO.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- ThermoGenesis Corp. (KOOL) announced that Kevin Montell Simpson has been appointed as the company's new president and chief operating officer, reporting directly to Philip Coelho, the company's chairman...

Roche receives FDA clearance for the COBAS AmpliScreen system.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Roche Diagnostics Corp. has announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance of the company's COBAS AmpliScreen System. The COBAS AmpliScreen System is...

Study: INACTINE PEN110 successfully inactivates viruses in red blood cells.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- V.I. Technologies (Vitex), Inc., (VITX) announced the publication of preclinical studies indicating that Vitex's INACTINE PEN110 Pathogen Reduction System has a wider spectrum of virucidal activity than...

Anthrogenesis Corp. announces license agreement.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- PharmaStem Therapeutics, Inc., and Anthrogenesis Corp. announced that they have entered into an agreement under which Anthrogenesis has obtained a license to PharmaStem's patent portfolio. ...

Canadian company reports earnings of 9 cents per share for quarter.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Cangene Corp. (CNJ) reported first quarter fiscal 2003 sales of CDN$24.7 million and earnings of $0.09 per share. Sales for the current quarter are up $7.0 million from the first quarter in fiscal...

Semidisabled herpes simplex virus vector effectively targets PBMCs.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- "Peripheral blood mononuclear cells (PBMCs) represent a significant target for gene delivery both for therapeutic and experimental purposes. Thus far however, it has proved difficult to develop vectors...

Data presented on Nipent shows its capability as a franchise compound.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) announced that 12 abstracts and presentations on the company's anticancer drug, Nipent, validating the drug's capability as a franchise compound with the ability to treat a...

No more medical roulette: Publisher says internet will change in 2003.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- NewsRx is celebrating its twentieth year as a publisher by adding 20 new weeklies. The company's CEO is predicting major changes in the publishing industry and Internet in 2003. The Atlanta-based...

Lentiviral vectors may provide alternative gene delivery system.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- "Efficient transduction of hematopoietic stem cells is a prerequisite for successful hematopoietic stem cell gene therapy. Oncoretroviral vectors are the most widely used vectors for hematopoietic gene...

Baxter to sell services component of renal business.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Baxter International, Inc., (BAX) announced its intent to divest the majority of the services component of its renal business and focus primarily on products used in the treatment of kidney disease. ...

Monoclonal antibodies characterized by laser backscattering.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- According to researchers in France, "A problem in immunohematology is to define the antibody quality which is related to its affinity expressed by the equilibrium constant. The activity of an antibody...

PRIMABioMed announces DCtag antigen collaboration with Institute Pasteur.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- PRIMABioMed, Ltd., the cancer and immunotherapy research and therapeutic development company, announced that its Panvax, Ltd., subsidiary has entered into a research collaboration with the Paris-based...

Study finds thalidomide overcomes drug resistance, is well tolerated.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Results of a study of thalidomide for treatment of relapsed and refractory relapsed multiple myeloma suggest further assessment is warranted for treatment with the compound. "Thalidomide (Thal) can...

HuMax-TAC program announced.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Genmab, A/S, announced its HuMax-TAC antibody program against the interleukin-2 receptor (IL-2R) target, also known as TAC, for use to treat organ transplant rejection. Genmab has identified a lead...

Company to submit NDA for Velcade (bortezomib) for Injection.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (MLNM) announced that the company intends to file a new drug application (NDA) with the U.S. Food and Drug Administration (FDA) to market Velcade as a treatment for...

New editor named to professional journal.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- The American Association of Blood Banks (AABB) and the journal, Transfusion have announced that Paul M. Ness, MD, has accepted the position as new editor of Transfusion. Transfusion is the official...

Stem cell transplant offers hope to children severely affected.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Pediatric patients with severe sickle cell disease have new reason to hope that their disease can be cured with new breakthroughs in myeoloablative allogeneic stem cell transplants. Researchers...

Interleukin-18 doesn't disrupt antileukemia effects.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The gamma interferon-inducing cytokine interleukin (IL)-18 can be safely used to ameliorate graft-versus-host reactions after stem cell transplantation,...

Intra-arterial catheter-based treatment effective against refractory graft-versus-host disease.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Israel have identified a novel method for treating stem cell recipients with refractory graft-versus-host reactions. "Graft-versus-host...

Genetic test for coagulation launched.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Tm Bioscience Corp. (TMC) announced the launch, ahead of schedule, of its first genetic test products. The Tag-It Mutation Detection Kits for coagulation will be used to identify patients with an...

Hemoglobin-based agent reduces need for transfusion during heart surgery.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- A phase II clinical trial conducted at Duke University Medical Center and five other U.S. institutions has shown that an agent made of purified human hemoglobin appears safe and may be effective when...

Capsid protein causes encephalitic inflammation by triggering cell suicide.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- The protein that forms the protective capsid surrounding the West Nile virus genetic material may contribute to the deadly inflammation associated with the virus. West Nile virus, which has rapidly...

FDA issues statement on blood industry's withdrawal of products.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has been working with the Centers for Disease Control and Prevention (CDC) and the blood banking community to assess and manage the potential risk of West...

Massachusetts company ships its first WNV product.
January 9, 2003... 2003 JAN 9 - (NewsRx.com & NewsRx.net) -- Boston Biomedica, Inc., (BBII) announced that it has released for sale and has begun to ship its first West Nile virus (WNV) product. The company also confirmed that it has already received firm...

Stem cells put to the test in UNC studies.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- More than 3000 scientific reports were presented at the American Society of Cell Biology's annual meeting, and one was a landmark study demonstrating - for the first time - that genetically altered...

Hematopoietic side population cells found in diverse adult tissues.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Most - if not all - forms of mature tissue contain cells capable of hematopoietic activity, researchers in Canada report. "Pluripotent hematopoietic stem...

Filtration device may reduce deaths among alcoholic hepatitis patients.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A technique that uses filtration devices to support the work of the liver could save the lives of people with acute alcoholic hepatitis. Alcoholic...

Epidemiology of inherited coagulation disorders studied in southern Iran.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Hematologists in Iran conducted a "comprehensive survey concerning the Shiraz Hemophilia Society and the associated hemophilia treatment center... in April 2002 to collect data on demographics, signs,...

Hydroxyurea seems to prevent recurrent SCA-related stroke.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- According to a study from Venezuela, "Cerebrovascular accident (CVA) is a major cause of morbidity and death in sickle cell anemia (SCA). Transfusion of packed erythrocytes is widely used to prevent...

Defibrotide improves peripheral blood cell mobilization.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A novel compound could make it easier to collect hematopoietic stem cells for transplantion, researchers in Italy report. "Defibrotide is a...

Erythropoietin output remains normal after nonmyeloablative transplantation.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Belgium have shed new light on the process of erythroid cell reconstitution after stem cell transplantation. "It is now well established...

Researchers uncover role of platelets in hardening of the arteries.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Scientists at the University of Virginia School of Medicine have discovered a new contributor to atherosclerosis, the most common form of hardening of the arteries. Marked by...

i-STAT prevails in arbitration with Nova Biomedical.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- i-STAT Corp. (STAT), a manufacturer of point-of-care diagnostic systems for blood analysis, announced that arbitration of a claim by Nova Biomedical Corp. seeking royalties under a license to Nova's...

Clinical data on solid oral heparin formulations released.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Emisphere Technologies, Inc., (EMIS) announced positive outcomes from a human study evaluating two solid oral heparin formulations, in tablet and capsule form, in healthy male volunteers. For each...

Novation extends blood gas contract with Radiometer America.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Novation, the supply chain management company for VHA, Inc., and University HealthSystem Consortium (UHC), has extended for a second consecutive year its blood gas contract with Radiometer America. ...

Scientists find fully differentiated blood cells remain able to switch identity.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Scientists at the University of Pennsylvania School of Veterinary Medicine have found a new wrinkle in the developmental biology dogma that cell differentiation occurs irreversibly as stem cells give...

Tailor-made sugar coated proteins manufactured in novel E. coli system.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- The prospect of using bacteria to manufacture complex human proteins for use in therapeutic drugs is a step closer thanks to new research from Switzerland and the U.K. Researchers reported they...

VA selects ProTime System for home blood coagulation testing study.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Thoratec Corp. (THOR) announced that its International Technidyne Corp. (ITC) subsidiary has been awarded a bid through its distributor, Quality Assured Services, Inc., to provide between 850 and...

Stem cell transplants prevent development in mice.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Hematopoietic stem cell (HSC) transplantation may prevent the development of diabetes, according to researchers in California. Georg F. Beilhack and...

Intrauterine treatment successful for severe case due to Kell alloimmunization.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Obstetricians in Lille, France, presented a case report of severe anti-Kell alloimmunization successfully treated with plasmapheresis and subsequent intrauterine transfusions. The doctors said...

Blood substitute company reports net loss of $9.6M.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Biopure Corporation (BPUR) announced its financial results for the fourth fiscal quarter and the fiscal year ended October 31, 2002. For the quarter, the company reported a net loss of $9.6...

Trial demonstrates Coagulin-B can achieve therapeutic level of factor IX.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Avigen, Inc., (AVGN), a biotechnology company developing gene therapies based on its AAV vector gene delivery technology, announced that its gene transfer product for the treatment of hemophilia B,...

Fludarabine phosphate followed by alemtuzumab is active first-line therapy.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Data from a phase II study showing that treatment with fludarabine phosphate followed by alemtuzumab is an active first-line therapy for patients with previously untreated, active B-cell chronic...

Rituximab boosts response rate in relapsed and refractory disease.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Data from a multicenter trial show that adding the monoclonal antibody rituximab to a fludarabine-containing chemotherapy regimen increased the response rate of patients with relapsed or refractory...

Breast cancer vaccine trial completed.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- A team of Harvard Medical School oncologists funded by Genzyme Molecular Oncology (GZMO) presented encouraging data from a phase I/II breast cancer vaccine clinical trial. The findings from the...

Pegylated liposomal doxorubicin, reduced-dose dexamethasone is safer therapy.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Cancer researchers at the Cleveland Clinic, Ohio, believe both substituting pegylated liposomal doxorubicin for doxorubicin in the current vincristine, doxorubicin, and dexamethasone regimen and...

Velcade patients experienced a reduction or stabilization of disease severity.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (MLNM) announced final results from the phase II SUMMIT trial (previously known as 025) for its investigational cancer drug Velcade in patients with relapsed and...

First data on Revimid presented.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Alan List, MD, professor of medicine and director of translational and clinical research at the Arizona Cancer Center, reported at the American Society of Hematology annual meeting (ASH) that 9 of 16...

Thalomid seems effective in treating myelofibrosis.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Celgene Corporation (CELG) announced that Ayalew Tefferi, MD, and colleagues at the Mayo Clinic presented data from a clinical trial of Thalomid (thalidomide) in combination with prednisone in...

Gleevec may be effective against second blood disease.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- A New York physician who has played a leading role in testing the Novartis drug Gleevec against leukemia is also finding it effective against a second disease involving blood-cell overproduction. ...

PNNL expands blood serum protein library.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- In a significant scientific advance, researchers at the Department of Energy's Pacific Northwest National Laboratory have identified or confirmed 490 proteins in human blood serum - nearly doubling the...

Study shows use of enoxaparin safe and effective, and cuts hospital stays.
January 16, 2003... 2003 JAN 16 - (NewsRx.com & NewsRx.net) -- Researchers at Brigham and Women's Hospital (BWH) announced the results of a study showing that 90 days of treatment with the blood thinner enoxaparin for acute pulmonary embolism (PE) is as safe and...