Blood Weekly articles from December 2004

Blood Weekly archives from December 2004

Cardiac troponins/NT-proBNP prognostic of amyloidosis PBSCT survival.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Cardiac troponins and N-terminal probrain natriuretic peptide are prognostic of survival for amyloidosis patients following peripheral blood stem cell transplantation. "Primary systemic amyloidosis...

Ganciclovir less toxic to myeloid SCs from cord blood than from bone marrow.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Ganciclovir is less toxic to myeloid progenitor cells from cord blood than from bone marrow. "We studied ganciclovir (GCV)-related neutropenia after preemptive therapy for cytomegalovirus infection:...

Hyaluronic acid-based scaffolds may stimulate heart valve tissue formation.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Hyaluronic acid-based scaffolds may be used to stimulate heart valve tissue formation. According to recent research published in the Journal of Biomedical Materials Research Part a, "Valvular...

Novel system allows characterization of scaffolds for soft tissue regeneration.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- A novel system allows for characterization of scaffolds for soft tissue regeneration. "Collagen threads with mechanical properties and fibrillar substructure similar to native tissue have been...

Novel cord blood cells identified with hematopoietic/chondrocytic potential.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Novel cord blood cells are identified with hematopoietic and chondrocytic potential. According to recent research from Canada, "With the exception of mature erythrocytes, cells within the human...

High-dose melphalan and ASCT improves quality of life of AL amyloidosis patients.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- High-dose melphalan and autologous peripheral blood stem cell transplantation improves the quality of life of AL amyloidosis patients. According to a study from the United States, "Treatment of AL...

Advances in ALL treatment may lead to elimination of irradiation.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Improved risk classification for patients with acute lymphoblastic leukemia (ALL), coupled with more intensive intrathecal chemotherapy for high risk patients and the use of a drug called dexamethasone,...

AML samples with FLT3/ITD mutations preferentially killed by FLT3 inhibition.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Pediatric acute myelogenous leukemia samples with FLT3/ITD mutations are preferentially killed by FLT3 inhibition. According to recent research from the United States, "Pediatric acute myelogenous...

Idarubicin and busulfan feasible for elderly AML patients undergoing ASCT.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Continuous infusion of idarubicin and oral busulfan is feasible for elderly patients with acute myeloid leukemia undergoing autologous stem cell transplantation. According to recent research from...

Inhaled CO has anti-inflammatory effects against ventilator-induced lung injury.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Inhaled carbon monoxide has antiinflammatory effects against ventilator-induced lung injury. "Ventilator-induced lung injury (VILI) is a major cause of morbidity and mortality in intensive care...

M4N induces growth arrest/apoptosis by inhibiting Cdc2 and survivin expression.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- M4N induces growth arrest and apoptosis by inhibiting Cdc2 and survivin expression. According to a study from the United States, "We previously reported that Sp1-dependent Cdc2 gene expression is...

Aspergillosis: Emerging infection in critically ill patients without malignancy.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Invasive apergillosis is an important emerging infection in critically ill patients without malignancy. "Using criteria designed for invasive aspergillosis (IA) in patients with cancer, we aimed to...

Indian Salmonella Typhi isolates have reduced ciprofloxacin susceptibility.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Salmonella Typhi isolates in India have reduced susceptibility to ciprofloxacin. "Typhoid fever continues to remain a health problem as the causative organism Salmonella Typhi has developed...

Pneumococcal virulence factor contributions to pathogenesis studied in mice.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Tissue-specific contributions of pneumococcal virulence factors to pathogenesis have been studied in a murine mode. Scientists in the United States "assessed the ability of Streptococcus pneumoniae...

Basal cell carcinoma rates continuously increasing in the Netherlands since 1973.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Basal cell carcinoma rates have been continuously increasing in the Netherlands since 1973. "This study is aimed to determine the characteristics of the trends in incidence of basal cell carcinoma...

MTT/ATP/calcein assays similarly predict potency of cytotoxic anticancer agents.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- MTT, ATP and calcein assays similarly predict the potency of cytotoxic anticancer agents. "Cell viability assays are important tools in oncological research and clinical practice to assess the tumor...

Company enters blood-bank market with new Lasette.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Cell Robotics International, Inc., (CRII) announced that it anticipates significant sales of its proprietary Lasette product to the blood-banking community based on the product's reception at the 2004...

Murine model developed for bone marrow failure.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- A murine model was developed for bone marrow failure. According to a study from the United States, "Infusion of parental lymph node (LN) cells into sublethally irradiated hybrid F1 recipients...

Suicide gene constructs may be effective graft-versus-leukemia therapy.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Suicide gene constructs may be effective graft-versus-leukemia therapy. According to recent research from the United States, "suicide gene therapy is one approach being evaluated for the control of...

Antiestrogenic DTACs inhibit estrogen receptor alpha-mediated transcription.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Antiestrogenic DTACs inhibit estrogen receptor alpha-mediated transcription. According to a study from the United States, "A novel class of pure antiestrogens,...

No correlation between B. cepacia complex wbiI RFLP genotype and species.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- There is no correlation between the Burkholderia cepacia complex wbiI RFLP genotype and species. According to recent research from the United States, "Gram-negative bacteria of the Burkholderia...

Intensive/short-term Burkitt lymphoma chemotherapy effective/manageable toxicity.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Intensive/short-term chemotherapy for Burkitt's lymphoma is effective and has manageable toxicity. "A very short, intensive pediatric chemotherapy program was tested in a consecutive...

ATryn maker reports third-quarter net loss of $7.2 million.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- GTC Biotherapeutics, Inc., (GTCB) reported its financial results for the third quarter ended October 3, 2004. The total net loss for the quarter was $7.2 million, or $0.18 per share, compared with...

Haemonetics makes equity investment, enters research collaboration.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Haemonetics Corp. (HAE) and Arryx, Inc., announced they will collaborate on the development of new technology for applications in a broad range of markets. Haemonetics will make an equity...

Nonionizing and ionizing radiation inactivate Calicivirus.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Nonionizing and ionizing radiation inactivate Calicivirus. According to a study from the Netherlands, "Noroviruses (previously Norwalk-like viruses) are the most common viral agents associated with...

PHB1/PHB2 identified as blood-borne tumor antigens.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Differential immunization has identified PHB1/PHB2 as blood-borne tumor antigens. "Early diagnosis of cancer is crucial for successful treatment. Noninvasive assays for detecting tumor-derived...

Deleterious hematological effects of CBP centrifugal pumps compared.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The deleterious hematological effects of two cardiopulmonary bypass (CPB) centrifugal pumps have been compared. CPB "induces hemolysis and the activation of the inflammatory and coagulation...

Thrombin inhibitor used in coronary intervention lowers costs, study shows.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The Medicines Company (MDCO) reported on a publication demonstrating significant in-hospital cost savings of $405 per patient (p The REPLACE-2 clinical trial economic study was authored by David J....

Celiac disease prevalence higher in Turkish population compared to Western world.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The prevalence of celiac disease is higher in Turkish populations compared to the Western world. According to recent research published in the journal Digestive Diseases and Sciences, "Celiac...

Stem cell focused biotech completes equity financing to support clinical trial.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- StemCells, Inc. (STEM) has consummated the private placement of 7,500,000 shares of its registered common stock at a purchase price of $3.00 per share, for gross proceeds to StemCells, Inc. of $22.5...

Low levels of cigarette smoke induce irreversible change in cell chromosomes.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Low levels of cigarette smoke induce irreversible change in cell chromosomes. "Exposure to cigarette smoke has long been linked to carcinogenesis, but the emphasis has been placed on mutational...

Cpe-positive Clostridium perfringens spores from feces isolated/enumerated.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Cpe-positive Clostridium perfringens spores from feces were isolated, and enumerated. According to published research from Finland, "A hydrophobic grid membrane filter-colony hybridization (HGMF-CH)...

Risk of community-associated MRSA infection is associated with several factors.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The risk of acquiring community-associated methicillin-resistant Staphylococcus aureus infection is associated with several factors. According to a study from the United States, "An outbreak of...

Thrombolytic therapy and angioplasty can effectively achieve cardiac reperfusion.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the efficacy of coronary angioplasty following conventional coronary thrombolysis in patients with acute myocardial infarction. Scientists in Japan report, "The...

Direct smear rapid/effective for diagnosis of Cyclospora cayetanensis infection.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The direct smear method is rapid and effective for the diagnosis of Cyclospora cayetanensis infection. "Cyclospora cayetanensis oocysts in the feces of humans from Kathmandu, Nepal were identified...

Oral valganciclovir equivalent to oral ganciclovir for CMV prevention.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Oral valganciclovir is equivalent to oral ganciclovir for the prevention of CMV infection. According to investigators writing in the journal Expert Opinion on Pharmacotherapy, "Herpes virus...

Lab designer's hematology analyzers ranked best in industry by consulting firm.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Sysmex America, Inc., a laboratory design company announced that their hematology analyzers have been ranked the best in the industry for performance and reliability for the fifth consecutive year,...

LightCycler PCR assay detects/characterizes enterotoxigenic Escherichia coli.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The LightCycler PCR assay detects and characterizes enterotoxigenic Escherichia coli. According to scientists in Germany, "To facilitate the diagnosis of enterotoxigenic Escherichia coli (ETEC)...

Medical equipment, renal device companies partner to manufacture dialysis system.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Sanmina-SCI Corporation (SANM), an electronics manufacturing services (EMS) company, and Renal Solutions, Inc., a medical device and healthcare service company, announced that Sanmina-SCI's Medical...

Blood samples from fatal and nonfatal cases of Ebola infection analyzed.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Scientists have analyzed human peripheral blood samples from fatal and nonfatal cases of Ebola hemorrhagic fever. "Peripheral blood samples obtained from patients during an outbreak of Ebola virus...

Virus-mediated therapy corrects acute intermittent porphyria in murine models.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Virus-mediated therapy corrects acute intermittent porphyria in murine models. "The aim of this study was to investigate the potential of gene therapy in the treatment of acute intermittent...

Transgenic EPO expression overcomes lethality caused by c-Kit(w/w) mutation.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Transgenic erythropoetin expression overcomes lethality caused by the c-Kit(w/w) mutation. According to published research from Germany, "Homozygous natural white-spotted (W) mutations in the gene...

Successful fatherhood, pregnancy possible for liver-transplanted FAP patients.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Male familial amyloidotic polyneuropathy (FAP) patients can overcome fertility complications and female FAP patients can have successful outcome of pregnancy after liver transplantation - welcome news...

Dialysis company reports Q3 income of $55.3 million.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- DaVita, Inc., (DVA), announced results for the quarter ended September 30, 2004. Net income for the 3 and 9 months ended September 30, 2004, excluding after-tax Medicare lab recoveries of $5.1...

Cyclosporin and MMF for GVHD prophylaxis associated with faster engraftment.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Cyclosporin and mycophenolate mofetil for graft-versus-host disease prophylaxis are associated with faster engraftment. "Cyclosporine (CSP) and short course methotrexate (MTX) have been the gold...

Valpha24+ NK cell number after HSCT may be related to the development of GVHD.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The number of Valpha24+ natural killer cells after HSCT may be related to the development of graft-versus-host disease. "Human Valpha24+ natural killer T (NKT) cells have an invariant T-cell...

HIV has less effect on point prevalence of TB disease than on TB incidence.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- HIV has less effect on the point prevalence of tuberculosis (TB) disease than on the incidence of TB. According to a study from Zimbabwe, "We hypothesized that rapid presentation may be a general...

Strategy developed to decrease global burden of TB/HIV.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- According to recent guidelines published in the European Respiratory Journal, "Tuberculosis (TB) in Europe is declining in countries in western and central Europe, but the burden is still high and...

Rapid field test sensitive and specific for detecting/differentiating HIV types.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- A rapid field test is sensitive and specific for the detection and differentiation of HIV types 1 and 2. "We evaluated a two-rapid-test serial algorithm using the Determine and Genie 11 rapid...

Simple and reproducible assay developed to screen HIV-1 subtypes.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- A simple and reproducible assay has been developed to screen HIV-1 subtypes. "After the initial development of a human immunodeficiency virus type 1 (HIV-1) subtype- screening too] by nested...

Persistent immune deficit in some patients irrespective of HIV viral load.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- There is a persistent immune deficit in some patients irrespective of HIV viral load. "HIV-1 infected patients adherent to HAART and displaying stable increases in CD4 T-cell counts differ in their...

Association between dual HIV-1 infection and elevated viral load set point.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- There is a significant association between dual HIV-1 infection and an elevated viral load set point. According to a study from South Africa, "This longitudinal study aimed to determine the...

Toll-like receptor 2 stimulation may contribute to HIV immunopathogenesis.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Toll-like receptor 2 stimulation may contribute to HIV immunopathogenesis. "Toll-like receptor 2 (TLR2) stimulation in monocytes may contribute to enhanced inflammation and viral replication in HIV...

E. bieneusi genotype D spores transmitted to SIV-infected macaques.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Enterocytozoon bieneusi genotype D spores were transmitted to SIV-infected macaques. "Microsporidia are obligate intracellular parasites that cause opportunistic infections in AIDS and other...

CD8 cells accumulate in brains of HIV-infected persons.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- CD8 cells accumulate in the brains of HIV-infected persons. "T lymphocytes are found within brains infected with human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) where they...

HIV-1 viral load not associated with intrapatient quasispecies heterogeneity.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- HIV-1 viral load is not associated with intrapatient quasispecies heterogeneity. "The human immunodeficiency virus type 1 (HIV-1) viral set point has been associated with the rate of disease...

Heat-shock protein 70 coprecipitates with Vpr from HIV-1-infected macrophages.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Heat-shock protein 70 coprecipitates with Vpr from HIV-1-infected macrophages. According to a study from the United States, "HIV-1 viral protein R (Vpr) shuttles between the nucleus and the...

High-throughput assay identifies CCR5/CD4-mediated HIV virus entry inhibitors.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- A novel, high-throughput cell fusion assay identifies CCR5/CD4-mediated HIV virus entry inhibitors. "This article describes the automation of an in vitro cell-based fusion assay for the...

Chinese blood centers to use rapid HIV Tests.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MMIRF) the global market leader in flow-through diagnostics for infectious diseases, announced that it has shipped 100,000 MiraWell Rapid HIV Tests to one of its distributors in the...

HIV-1 integrase nuclear import inhibited by styrylquinoline derivatives.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- HIV-1 integrase nuclear import is inhibited by styrylquinoline derivatives. "Nuclear import of HIV-1 preintegration complexes (PICs) allows the virus to infect nondividing cells. Integrase (IN), the...

Lopinivir efficacy decreases following cotransfection of wild-type HIV clones.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The efficacy of lopinivir decreases following cotransfection of wild-type HIV clones. "The impact of cotransfection of mixtures of mutant and wild type (WT) virus on the observed phenotype and...

Minocycline inhibits HIV-1 infection in microglia.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Minocycline, a tetracycline, inhibits HIV-1 infection in microglia. According to scientists writing in the Journal of Neurovirology, "Human immunodeficiency virus type 1 (HIV-1) infection of the...

Protease inhibitor fosamprenavir potent against advanced HIV disease.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The protease inhibitor fosamprenavir is potent against advanced HIV disease. "Fosamprenavir, the prodrug formulation of amprenavir, is a protease inhibitor recently approved in the US for the...

Trim5-cyclophilin A fusion protein from owl monkey kidney cells restricts HIV-1.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Trim5-cyclophilin A fusion protein from owl monkey kidney cells restricts HIV-1. According to recent research published in the journal Proceedings of the National Academy of Sciences USA, "Lv1...

Altered TNFSF CD95 receptor expression reduces B cell survival in HIV infection.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Altered TNF superfamily CD95 receptor expression reduces B cell survival in HIV infection. According to recent research from the United States, "Human immunodeficiency virus (HIV) infection leads...

Wild-type breast cancer resistance protein induces cellular resistance to NRTIs.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- The wild-type breast cancer resistance protein induces cellular resistance to nucleoside reverse transcriptase inhibitors. According to a study from Japan, "Breast cancer resistance protein...

Protothecal arthritis and tenosynovitis resulted from hematogenous dissemination.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Protothecal arthritis and tenosynovitis resulted from hematogenous dissemination. According to investigators in the United States, "Achloric algae of the Prototheca species are a rare cause of...

HIV viral load increases in breast milk following ZDV discontinuation.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- HIV viral load increases in breast milk following discontinuation of zidovudine. "Perinatal zidovudine (ZDV) prophylaxis decreases rates of perinatal transmission of human immunodeficiency virus...

Patients with heart failure on coumarin should be closely monitored.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Researchers have reported on the risk of overanticoagulation in patients with heart failure on coumarin anticoagulants. According to recent research published in the British Journal of Haematology,...

IL-1 receptor-1 gene polymorphism associated with increased H. pylori risk.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- An IL-1 receptor-1 gene polymorphism is associated with an increased risk H. pylori infection, but not stomach cancer. According to recent research published in the journal Digestive Diseases and...

Imatinib does not normalize blood dendritic cell levels in leukemia patients.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Imatinib does not normalize blood dendritic cell levels in leukemia patients. "Human blood dendritic cells (DC) comprise plasmacytoid DC (PDC) and myeloid DC (MDC), which both prime antitumor T-cell...

DC production in myelodysplastic syndrome results in ineffective dendritopoiesis.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Dendritic cell production in myelodysplastic syndrome results in ineffective dendritopoiesis. According to published research from Greece, "Myelodysplastic syndrome (MDS) is a stem cell disorder...

IgG treatment in pregnancy reduces severity of rare liver condition in newborns.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Treatment with high-dose immunoglobulin G (IgG) during pregnancy lessens the severity of hemochromatosis (NH), a rare, devastating, gestational disease with abnormal iron accumulation in the liver and...

Factor IX launched for the treatment of hemophilia B in Spain.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Grifols has launched Factor IX Grifols for the treatment of hemophilia B in Spain, expanding their plasma-derivatives product portfolio for the hemophilia community. Factor IX Grifols is a high...

European authorities give positive opinion for Fendrix vaccine.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Further to the filing for regulatory approval with the European Agency for the Evaluation of Medicinal Products (EMEA) in May 2003, GlaxoSmithKline Biologicals (GSK Bio) has received a positive opinion...

Drug combination shows promise in treating hepatitis C.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Interim study results indicate a certain drug combination treatment may suppress the hepatitis C virus more quickly than another. Researchers at Saint Louis University School of Medicine and six...

CD46-mediated costimulation enhances early TCR/CD3 signaling in CD4+ cells.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- CD46-mediated costimulation enhances early TCR/CD3 signaling in CD4+ T lymphocytes. "The role of membrane cofactor protein (MCP, CD46) on human T cell activation has been analyzed. Coligation of CD3...

Hemagglutinin of 1918 pandemic influenza A virus confers enhanced pathogenicity.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Hemagglutinin of the 1918 pandemic influenza A virus confers enhanced pathogenicity. According to a study from the United States, "The 'Spanish' influenza pandemic of 1918-19 was the most...

Report describes the keys to weaning patients from inotropic support.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the question of which patients can be weaned from inotropic support within 24 hours after cardiac surgery. According to recent research published in the journal Heart...

Lower cut-off proposed for galactomannan detection in neutropenic/SCT patients.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Lower cut-off points are proposed for galactomannan detection in neutropenic and stem cell transplantation patients. "The recent advent of an improved commercial serum enzyme-linked immunosorbent...

Generation of NO from NO[subscript]2 by xanthine oxidoreductase protects the myocardium.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. According to a study from England, "Nitric oxide (NO) is thought to protect against the...

Kaposi sarcoma-associated herpesvirus transmission likely via saliva.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- Kaposi sarcoma-associated herpesvirus transmission is likely via saliva. According to investigators in the United States, "Among 233 children, Kaposi sarcoma-associated herpesvirus (KSHV) DNA was...

Renal papilla is a niche for kidney stem cells.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- "Many adult organs contain stem cells, which are pluripotent and are involved in organ maintenance and repair after injury. In situ, these cells often have a low cycling rate and locate in specialized...

Abnormal relapse of atypical hemolytic uremic syndrome described.
December 2, 2004... 2004 DEC 2 - (NewsRx.com & NewsRx.net) -- An abnormal relapse of atypical hemolytic uremic syndrome (HUS) has been described in a pediatric kidney transplant recipient. Atypical HUS "frequently leads to end-stage renal failure and can...