Blood Weekly articles from August 2004

Blood Weekly archives from August 2004

Hepatitis C virus associates with thrombocytopenia formation.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus associates with thrombocytopenia formation. "Chronic hepatitis C virus (HCV) infection has also been associated with the development of several extrahepatic alterations, including...

Single recombinant anti-RhD IgG prevents RhD immunization.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- A single recombinant anti-RhD IgG prevents RhD immunization. "A single recombinant immunoglobulin G1 (IgG1) anti-RhD antibody (MonoRho) was compared with a currently used polyclonal anti-RhD...

Donor treatment with pegylated G-CSF promotes transplantation tolerance.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Donor treatment with pegylated G-CSF promotes transplantation tolerance. "We investigated whether the protection from graft-versus-host disease (GVHD) afforded by donor treatment with granulocyte...

IL-10/TNF alpha region haplotypes predict mortality after unrelated donor SCT.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- IL-10 and TNF alpha region haplotypes predict mortality after unrelated donor stem cell transplantation. According to published research from England, "Certain cytokine gene polymorphisms have been...

Steroid and cyclosporine A use are risk factors for bone loss following SCT.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Steroid and cyclosporine A use are risk factors for bone loss following stem cell transplantation. "Transplantation-associated bone loss is a well-known phenomenon; however, effects of...

Novel FLT3 inhibitors may be considered to treat hyperdiploid or relapsed ALL.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Novel FLT3 inhibitors may be considered for the treatment of hyperdiploid or relapsed acute lymphoblastic leukemia. "Activating mutations of the FLT3 receptor tyrosine kinase are common in acute...

FLT3 mutations in AML adversely associate with CR with intensive chemotherapy.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- FLT3 mutations are adversely associated with complete remission in AML patients given intensive chemotherapy. "The prognostic impact of FLT3 mutations on the outcome of patients with diploid AML,...

Factors affecting good and poor CD34+ cell mobilization in AML determined.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The factors affecting good and poor CD34+ cell mobilization in AML have been determined. According to a study from Italy, "The factors possibly affecting the collection of peripheral blood stem...

Timed sequential therapy for AML patients over 60 tolerated but unsatisfactory.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Timed sequential therapy for acute myeloid leukemia patients over 60 was well tolerated but unsatisfactory. "Acute myeloid leukemia (AML) in the elderly is a serious problem characterized by poor...

Pathway of platelet procoagulant activity is regulated by IQGAP1.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1. According to a study from the United States, "Circulating blood platelets regulate the initial phase of the...

Antipsychotics upregulate bcl-2 mRNA/protein in frontal cortex and hippocampus.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Antipsychotics upregulate bcl-2 mRNA and protein in the frontal cortex and hippocampus. "To investigate whether atypical antipsychotic drugs exert an effect on the neuroprotective protein Bcl-2,...

Styrylquinolines do not interfere with HIV entry but act before integration.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- SQLs do not interfere with HIV entry but act before integration. According to a study from France, "We have previously shown that styrylquinolines (SQLs) are integrase inhibitors in vitro. They...

New methods ease the separation of antisense oligonucleotide in plasma.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- New methods ease the separation of antisense oligonucleotide in plasma. "A novel approach is presented for the direct injection, and subsequent separation, of antisense phosphorothioate...

P300 regulates p53-dependent apoptosis in colorectal cancer cells.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- P300 nucleoprotein regulates p53-dependent apoptosis in colorectal cancer cells. "Activation of the tumor suppressor p53 by DNA damage induces either cell cycle arrest or apoptosis, but what...

Southeastern Michigan Red Cross says blood banks out of type O, others types low.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The Southeastern Michigan American Red Cross Blood Region reports that the available supply of type O, the most critical type, is at zero. Other blood types are below acceptable levels and can be...

Korean regulatory body approves blood plasma volume expander.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- BioTime, Inc., (BTX) announced that its South Korean licensing partner CJ Corp. has received regulatory approval from the Korea Food and Drug Administration (KFDA) for Hextend, the company's...

Galileo licensed for use in Japan and Canada.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Immucor, Inc., (BLUD) announced that the Japanese Ministry of Health and Health Canada's Therapeutic Products Directorate have licensed Galileo for distribution in their respective jurisdictions. ...

BLM and CAF-1 coordinate to promote survival in response to DNA damage.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- BLM and CAF-1 coordinate to promote survival in response to DNA damage. According to recent research published in the journal Molecular and Cellular Biology, "Bloom's syndrome (BS) is a genomic...

PCL-TCP scaffolds seeded with osteoblasts sustains osteogenic expression.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Poly-caprolactone 20% tricalcium phosphate scaffolds seeded with osteoblasts sustains excellent osteogenic expression. According to published research from Singapore, "Our strategy entails...

PRDC is a potent BMP antagonist with a wide tissue expression pattern.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Protein related to DAN and cerberus (PRDC) is a potent bone morphogenetic protein antagonist with a wide tissue expression pattern. "Bone morphogenetic proteins (BMPs) are important for body...

Cancer therapeutics development company files IND for metastatic breast cancer.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- NeoRx Corporation (Nasdaq:NERX) announced that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) for a phase II clinical study of STR (skeletal...

ER codon 594/HER2 codon 655 polymorphisms not associated with breast cancer risk.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- ER codon 594 and HER2 codon 655 polymorphisms are not associated with an increased breast cancer risk. According to a study from Turkey, "The estrogen receptor (ER) and the human epithelial growth...

Increased serum folate levels associated with reduced breast cancer risk.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Increased serum folate levels are associated with reduced breast cancer risk. "Breast cancer risk may be associated with folate status or the C677T genotype of the methylenetetrahydrofolate...

Novel phosphorylation sites in HMGN1 protein from breast cancer cells identified.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Novel phosphorylation sites in high-mobility group N1 protein from breast cancer cells have been identified. According to recent research published in the journal Biochemistry, "High-mobility group...

Tamoxifen metabolite R-isomer forms more DNA adducts in liver cells.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- A tamoxifen metabolite R-isomer forms more DNA adducts in liver cells. "The antiestrogenic drug tamoxifen forms DNA adducts in rat liver through two genotoxic metabolites, a-hydroxytamoxifen and...

Molecular markers useful to detect various stages of non-small-cell lung cancer.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Molecular markers are useful for detecting various stages of non-small-cell lung cancer. According to published research from Russia, "Studies performed in the recent decade in the Laboratory of the...

Mechanism of benzene-induced leukemia elucidated.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The mechanism of benzene-induced leukemia has been elucidated. According to published research from the United States, "Acute myeloid leukemia and chronic lymphocytic leukemia are associated with...

Endothelial progenitor cell mobilization encourages aortic repair.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Endothelial progenitor cell mobilization encourages aortic repair. "Rapid endothelialization of prosthetic vessels is essential to avoid fatal complications. We hypothesized that there may be...

Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation. According to published research from Japan, "Bcr-Abl tyrosine kinase inhibitor induces apoptosis and erythroid...

MAX2 reproducibly estimates average per patient risk for chemotherapy toxicity.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- MAX2 reproducibly estimates average per patient risk for chemotherapy toxicity. According to recent research published in the European Journal of Cancer, "Cancer patients, especially the elderly,...

siRNA against NF-kappaB p65 subunit enhances sensitivity to chemotherapeutics.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- siRNA directed against the NF-kappaB p65 subunit enhances sensitivity to chemotherapeutics. "In preclinical tumor models, inhibition of nuclear factor-kappaB (NF-kappaB) has been associated with...

Alemtuzumab effective therapy for CLL with p53 mutations and deletions.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. "The presence of p53 mutation or deletion predicts for poor response to conventional therapy...

IL-11 may improve thrombocytopenia associated with imatinib therapy in CML.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- IL-11 may improve thrombocytopenia associated with imatinib therapy in chronic myelogenous leukemia. According to published research from the United States, "During therapy with imatinib (Gleevec),...

Process uses riboflavin and light to reduce pathogens in donated blood.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Targeting the improved safety of transfusion medicine, the Mirasol PRT process uses riboflavin (also known as vitamin B2) and light to reduce the level of pathogens found in donated blood components,...

Agreement with Nycomed for development of Oxygent terminated.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Alliance Pharmaceutical Corp. (ALLP) announced that Nycomed, its development partner for Oxygent in the European Union, has provided notice that it is terminating the recently announced license...

Herbs and spices have antimicrobial and chemopreventive properties.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Herbs and spices have antimicrobial and chemopreventive properties. "Herbs and spices have been used for generations by humans as food and to treat ailments. Scientific evidence is accumulating that...

Studies show Lovenox as an effective treatment of acute coronary syndromes.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Results of two new randomized clinical studies confirm that Lovenox (enoxaparin sodium injection) is an effective and safe antithrombotic agent in patients with non-ST-segment elevation (NSTE) acute...

Real-time qPCR more sensitive than COBAS Amplicor for CMV DNA detection.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- A real-time quantitative PCR assay is more sensitive than the COBAS Amplicor assay for cytomegalovirus (CMV) DNA detection. According to a study from Sweden, "A duplex quantitative real-time PCR...

53BP1 required for class switch recombination.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- 53BP1 is required for class switch recombination "53BPI participates early in the DNA damage response and is involved in cell cycle checkpoint control. Moreover, the phenotype of mice and cells...

Scientists discover key step in the development of nerve cells.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Scientists at the Montreal Neurological Institute at McGill University have discovered a gene that is necessary for the correct development of the part of the brain that controls autonomic functions...

FDA grants waived status under CLIA for lipids test panel.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Abaxis, Inc., (ABAX), a medical products company manufacturing point-of-care blood analysis systems, announced that the U.S. Food and Drug Administration has granted waived status under Clinical...

First predictive diagnostic to combat high sepsis mortality rates released.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The release of ABP-26, a predictive diagnostic for detecting early signs of sepsis, has been announced by Signet Laboratories, Inc. The diagnostic helps prevent onset and curb mortality rates. ...

Methylated DNA collected by tampons detects endometrial cancer.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Methylated DNA collected by tampons detects endometrial cancer. According to recent research published in the journal Cancer Epidemiology Biomarkers & Prevention, "This proof of principle study...

1,4-Naphthoquinone derivatives have antiviral/antifungal/anticancer activities.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- 1,4-Naphthoquinone derivatives have antiviral/antifungal/anticancer activities. According to recent research from India, "The synthesis and evaluation of some 2-substituted-1,4-naphthoquinones 2,...

New product removes high-abundance proteins from mouse blood serum.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Agilent Technologies, Inc., (A) introduced the second in a new line of proteomics products that removes high-abundance proteins from blood serum. The Multiple Affinity Removal Column removes the...

EBV viral load increases and reaches setpoint after HIV seroconversion.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Epstein Barr virus viral load increases and reaches a setpoint after HIV seroconversion. "In contrast to the situation in the post-transplant setting, in HIV-infected individuals an elevated EBV...

Fertility preservation in females receiving cancer therapy is reviewed.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Fertility preservation in females receiving cancer therapy is reviewed. "In the Unites States alone, >650,000 women will be afflicted by cancer in 2003, and 8% of these cases will be aged "Due...

Biopharmaceutical company announces going concern qualification.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Pursuant to Nasdaq Marketplace Rule 4350(b)(1)(B), Hemosol Corp. (HMSL) announced that the auditors' report on the financial statements of Hemosol Corp's predecessor, Hemosol Inc., contained in Hemosol...

Medical instruments developer reports second-quarter sales higher than expected.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Ventana Medical Systems Inc. (VMSI) announced preliminary second quarter sales of approximately $42 million, which are higher than expected and were driven by strong growth in both instrument and...

Pneumocystis jirovecii identified in lung tissue sections from SIDS victims.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Pneumocystis jirovecii was identified in lung tissue sections from sudden infant death syndrome victims. According to recent research published in the journal Microbiology - SGM, "Previous studies...

Similar P. jirovecii genotypes found in different forms of infection.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- There are similar Pneumocystis jirovecii genotypes in different forms of Pneumocystis infection. According to recent research from France, "This study describes the genotyping of P. jirovecii...

Runx3 major growth regulator of gastric epithelial cells.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Runx3 is a major growth regulator of gastric epithelial cells. "Runx3 is expressed by gastric epithelial cells throughout development. Mice whose Runx3 gene has been knocked out died soon after...

Promoter element location directs testis-specific Hst70/Hsp70.2 expression.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The promoter element location is needed to direct testis-specific Hst70/Hsp70.2 gene expression. According to a study from Poland, "The rat Hst70 gene and its mouse counterpart Hsp70.2 are...

Role of TEL-AML1 fusion gene in molecular pathogenesis of ALL elucidated.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The role of the TEL-AML1 fusion gene in the molecular pathogenesis of acute lymphoblastic leukemia is elucidated. "Balanced chromosomal translocations are frequently associated with hematopoietic...

Four-color multiplex assays detect single nucleotide polymorphisms.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Four-color multiplex assays detect single nucleotide polymorphisms. "We developed a real-time multiplex four-color assay for the simultaneous detection of the factor V Leiden (FVL) and prothrombin...

Structure and function of chromosome 13q14 characterized.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The structure and function of chromosome 13q14 has been characterized. "Works on chromosome 13 mapping supported by the Russian program Human Genome are reviewed. Emphasis is placed on studies of...

Lentiviral vectors mediate CRE recombinase-inducible RNA interference.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Lentiviral vectors mediate CRE recombinase-inducible RNA interference. "Recently, several systems designed to trigger RNA interference by using small hairpin RNA driven by polymerase III promoters...

MAGE-A1-expressing tumor cell 5' region less methylated than other parts of gene.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The 5' region of MAGE-A1-expressing tumor cells are less methylated than other parts of gene. "Several male germ line-specific genes, including MAGE-A1, rely on DNA methylation for their repression...

DC stimulation of donor CD8+ T cells may be useful for prevention of GVHD.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Dendritic cell stimulation of donor CD8+ T cells may be useful for prevention of graft versus host disease. "Graft versus host disease (GVHD) is triggered by host antigen-presenting cells (APCs)...

Clinical trials commence for HIV rapid test.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Chembio Diagnostics, Inc., (CEMI.OB) announced at the Fifteenth World Aids Conference that it has commenced clinical trials of the Sure Check HIV and HIV Stat-Pak - the company's proprietary lateral...

Continued injection drug use not associated with progression to AIDS in women.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Continued injection drug use is not associated with a progression to AIDS in infected women. "Data from a prospective, multicentered study of HIV infection in women (HIV Epidemiology Research Study...

Kidney transplant in HIV infection plausible in era of HAART/immunosuppressives.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Kidney transplantation in HIV-infected patients is plausible in the era of HAART and immunosuppressive therapy. "Before the era of highly active antiretroviral therapy, kidney transplant recipients...

Chromatin structure affects HIV-1/ASV integration site selection opposite ways.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The chromatin structure affects the HIV-1/ASV integration site selection in opposite ways. According to recent research published in the Journal of Virology, "Integration of viral DNA into the host...

Differentially expressed genes in HIV-1-resistant cells analyzed by microarray.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Differentially expressed genes in HIV-1-resistant cells were analyzed using cDNA arrays. According to scientists at Columbia University, "We have previously isolated two matched transformed human T...

Diketo acid integrase inhibitor resistance impairs HIV-1 replication/integration.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Diketo acid integrase inhibitor resistance impairs HIV-1 replication and integration. "The diketo acids are potent inhibitors of HIV integrase (IN). Mutations in IN, T66I, S153Y and M154I, as well...

HIV-induced macrophage alterations play role in HIV encephalopathy pathogenesis.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- HIV-induced macrophage alterations play a role in the pathogenesis of HIV encephalopathy. "This study was performed to quantitate and characterize the mononuclear phagocytes (MPs) in human...

Resistance mutations sustain or enhance CTL recognition of HIV-1 Pol epitopes.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Antiretroviral resistance mutations sustain or enhance cytotoxic T lymphocyte (CTL) recognition of HIV-1 Pol epitopes. "Antiretroviral drug resistance and escape from cytotoxic T lymphocytes (CTL)...

Species-specific tropism determinants found in the HIV-1 capsid.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Species-specific tropism determinants were found in the HIV-1 capsid. According to a study from the United States, "Retroviral tropism is determined in part by cellular restriction factors that...

Tsg-101 protein has role in HIV Gag particle release.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The Tsg-101 protein has a role in HIV Gag particle release. According to recent research published in the Journal of Virology, "Human immunodeficiency virus type 1 particles form by budding at the...

NNRTI stereochemistry and regiochemistry profoundly affect anti-HIV activity.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The stereochemistry and regiochemistry of non-nucleoside reverse transcriptase inhibitors profoundly affect their anti-HIV activity. "Chiral derivatives of several substituted halopyridyl and...

Subcutaneous IL-2 therapy maintains CD4 cell increases in HIV-1 infection.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Subcutaneous IL-2 therapy maintains CD4 cell increases in HIV-1 infection. According to recent research from the United States, "Studies establishing that intermittent subcutaneous interleukin-2...

BCL-6 mutations seen in HIV-related pulmonary lymphoproliferative disorders.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- BCL-6 mutations were seen in HIV-related pulmonary lymphoproliferative disorders. "We used a PCR and sequence procedure to analyze the Ig V-H gene and the mutations in the 5' regulatory regions of...

HAART increases survival of patients with HIV-associated Hodgkin disease.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Highly active antiretroviral therapy increases the survival of patients with HIV-associated Hodgkin disease. According to a study from Germany, "Hodgkin disease (HD) is the most common nonacquired...

Notch-1 signaling mediates BMS influence on hematologic malignant cell growth.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Notch-1 signaling mediates bone marrow stroma influence on hematologic malignant cell growth and survival. According to a study from the United States, "The bone marrow (BM) microenvironment plays...

Hemophagocytic syndrome can erupt after liver transplantation.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Hemophagocytic syndrome can erupt after liver transplantation. According to a study from Spain, "The hemophagocytic syndrome is defined as a proliferation of phagocytic macrophages in the bone...

Novel human platelet septin SEPT8 is interaction partner of SEPT4.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The novel human platelet septin SEPT8 is an interaction partner of SEPT4. "Septins are a family of GTP-binding proteins, which are essential for active membrane movement such as cytokinesis and...

Malignant hematopoietic disease from internal exposure to Pu-239 uncertain.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Development of malignant hematopoietic disease from internal exposure to Pu-239 is still uncertain. According to recent research published in the journal Health Physics, "Neither Fisher's Exact...

HCV screening for drug users/transfusion patients only is most cost-effective.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus screening for drug users and transfusion patients only is the most cost-effective. According to recent research published in the journal Gastroenterologie Clinique Et Biologique,...

History of intravenous drug use strongest predictor for HIV/HCV coinfection.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- A history of intravenous drug use is the strongest predictor for HIV/HCV coinfection. "The declining incidence of AIDS-related opportunistic diseases among people with HIV infection has shifted the...

PIN1 overexpression/beta-catenin gene mutations distinct oncogenic events in HCC.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- PIN1 overexpression/beta-catenin gene mutations are distinct oncogenic events in hepatocellular carcinoma. "The peptidyl-prolyl-isomerase, PIN1, upregulates beta-catenin by inhibiting its...

Sunscreen immune protection factors determined using dendritic cell suspensions.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Sunscreen immune protection factors have been determined using dendritic cell suspensions. According to published research from France, "In a previous study, we have used UVB-irradiated human skin...

Gene profiles could improve acute leukemia diagnosis.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Microarray data will help classify major subtypes of acute myeloid leukemia and speed understanding of the altered biology that causes this cancer in adults and children The results of a microarray...

Links Fore Leukemia raises $300,000 for The Leukemia & Lymphoma Society.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The prestigious Stonebriar Country Club in Frisco was the setting recently of the 8th Annual Jim Willis Memorial Links Fore Leukemia Golf Tournament. Over 185 players turned out to play golf on...

Mechanism of leukemogenesis described.
August 5, 2004... 2004 AUG 5 - (NewsRx.com & NewsRx.net) -- The mechanism of leukemogenesis by inv(16) chimeric gene CBFB/PEBP2B-MHY11 is described. According to published research from Japan, "Inv(16)(p13q22) is associated with acute myeloid leukemia...