Blood Weekly articles from April 2003

Blood Weekly archives from April 2003

Autologous stem cell transplantation can be beneficial.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Multiple sclerosis (MS) sufferers may benefit from hematopoietic stem cell autografts, researchers in Spain say. Enric Carreras and colleagues at the...

Donor pretreatment with IL-18 prevents acute GVHD.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Pretreatment of hematopoietic stem cell donors with interleukin (IL)-18 may prevent acute graft-versus-host disease (GVHD) after transplantation, researchers in...

Drug use and blood products transmit hepatitis C virus infections in Uzbekistan.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Intravenous drug use and blood products transmit hepatitis C virus infections in Uzbekistan. According to a study from Japan, "the aim of this study was to identify hepatitis C virus (HCV) genotypes...

Different blood cell types have varying drug resistance rates.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Different blood cell types have varying drug resistance rates during highly active antiretroviral therapy (HAART) for HIV infection. In a recent study from Australia, researchers conducted "a...

Extended thromboprophylaxis recommended after hip or knee replacement.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Doctors in private orthopedic practice recommend extended thromboprophylaxis (once daily for four weeks) after hip or knee replacement. "Early discharge from the hospital after total joint...

Transplanted bone marrow generates new neurons in human brains.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Transplanted bone marrow can led to the production of new neurons in human brains. "Adult bone marrow stem cells seem to differentiate into muscle, skin, liver, lung, and neuronal cells in rodents...

Bone marrow grafts may be best option with matched unrelated donors.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Bone marrow grafts may be the best choice for acute lymphoblastic leukemia (ALL) patients with HLA-identical but unrelated stem cell donors. Researchers from France "analyzed data for 213 patients...

Selective inhibition of alternative pathway protects kidneys from ischemic ARF.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Selective inhibition of alternative pathway protects kidneys from ischemic ARF. "Ischemia/reperfusion (I/R) injury of the kidney is a common cause of acute renal failure (ARF) and is associated with...

Research: At-home dialysis therapy may be an effective option.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Research findings from the European APD (automated peritoneal dialysis) Outcomes Study (EAPOS), suggest that APD, a home-based dialysis treatment for people with end-stage renal disease (ESRD), is a...

FDA warns of bacteria-tainted fake drug.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Hospitals and pharmacies may have unknowingly bought a counterfeit version of the antianemia drug Procrit - and the useless product also is contaminated with bacteria, the government warned March 11,...

Anthrapyridazone derivatives are active, even on multidrug resistant cells.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Anthrapyridazone derivatives are active, even on multidrug resistant cells. According to recent research from Poland, "A series of anthrapyridazone derivatives with 1-2 basic side chains at various...

Prehospital trauma trial with PolyHeme gets clearance.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Northfield Laboratories, Inc., (NFLD) announced that it has received clearance from the U.S. Food and Drug Administration (FDA) to proceed with its pivotal phase III prehospital trial with PolyHeme, the...

The alcaloid swainsonine has a significant stimulatory effect on bone marrow.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- The alcaloid swainsonine has a significant stimulatory effect on bone marrow. "The immunomodulatory alkaloid swainsonine (8alphabeta-indolizidine-1alpha,2alpha,8beta-triol) has potential for...

Thrombin generation correlates with biomarkers in advanced prostate cancer.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Thrombin generation correlates with biomarkers in advanced prostate cancer. According to recent research from the United States, "thrombin generation is increased in men with advanced prostate...

Thromboembolism precedes cancer; should be considered risk marker.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Thromboembolism precedes cancer; it should be considered a marker for risk. According to a study from the United States, "Thromboembolic (TE) events preceding cancer have been observed. Some...

Cyclophilin A binding region blocks lentiviral vector simian cell transduction.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- The cyclophilin A binding region plays a key role in the inability of HIV-based lentiviral vectors to transduce simian cells. "HIV-1 replication in simian cells is restricted at an early postentry...

Syndecan plays key role.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Syndecan plays a key role in HIV pathogenesis. According to a recent study from the United States, the protein "functions as an in trans HIV receptor." M. D. Bobardt and colleagues at the...

Cytokine profile changes linked to effective treatment.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Certain changes in cytokine levels are associated with successful antiretroviral treatment in HIV patients. Researchers in France "investigated the cytokine profiles of 14 treatment-naive...

Adeno-associated virus extends gene transfection in hemophilia models.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Adeno-associated virus extends gene transfection in hemophilia models. "The goal of our work has been to establish an experimental basis for gene transfer as a method of treating hemophilia, an...

Strong static magnetic field had no effect on normal lymphocytes.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- A strong static magnetic field had no effect on normal lymphocytes. "We investigated whether static electromagnetic fields (EMFs) at a flux density of 4.75 T, generated by an NMR apparatus (NMRF),...

An autocrine-paracrine loop potentiates megakaryocytic maturity through Flt1.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- An autocrine-paracrine loop potentiates megakaryocytic maturity through Flt1. According to a study from the United States, "the expression/function of vascular endothelial growth factor (VEGF)...

Off-pump coronary artery bypass grafting feasible for chronic dialysis patients.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Off-pump coronary artery bypass grafting (CABG) is feasible for chronic dialysis patients. According to a recent study from Greece, off-pump CABG "has been recently revived, because cardiopulmonary...

NovoSeven is effective for surgery patient with previous history of inhibitors.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Surgeons in Florida reported a case study of a hemophilia A patient with a past history of inhibitors for whom NovoSeven was an effective treatment modality when he underwent subsequent surgery. ...

Osteotomy for hemophilic arthropathy of the knee especially aids young patients.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Orthopedists at the University of Bonn evaluated "the long-term value of corrective osteotomy around the knee... by means of clinical and radiographic parameters." According to a report by T....

rFVIIa efficacious in treatment of major bleeding episodes.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- rFVIIa efficacious in treatment of major bleeding episodes. "Recombinant activated factor VII (rFVIIa, 'NovoSeven') is indicated for the treatment of spontaneous and surgical bleeding in patients...

Navy to help fund and conduct clinical trial of Hemopure in trauma.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Biopure Corp. (BPUR) announced that it has signed a cooperative research and development agreement (CRADA) with the U.S. Naval Medical Research Center (NMRC) that will enable the NMRC to participate in...

Rapid immunoassays suitable for Clostridium difficile detection.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Rapid immunoassays are suitable for diagnosing Clostridium difficile infection. C. difficile "is one of the most frequent causes of nosocomial gastrointestinal disease," explained researchers in the...

Post-transplant monitoring by immune parameters may be preferable to drug level.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Post-transplant monitoring by immune parameters may be preferable to drug level. "The current standard of monitoring transplant patients by drug levels is not optimal because it does not take into...

Lithospermum radix extract inhibits antiapoptosis kinase in tumor cells.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- A plant extract with antileukemia activity works by inhibiting an antiapoptosis kinase in malignant cells. According to a study from Japan, "beta-Hydroxyisovalerylshikonin (beta-HIVS), which was...

Novel assay identifies T cells responsible for therapeutic, destructive stem cell graft activity.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- A novel assay can identify T-cell subsets responsible for the therapeutic and destructive effects of hematopoietic stem cell grafts in leukemia patients. "Although graft-versus-host (GVH) disease...

Action taken by FDA to mandate bar codes on human drug products and blood.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- As manufacturers face intense pressure to help reduce the number of medical errors, the U.S. Food and Drug Administration (FDA) has created a proposed rule to mandate bar codes on all human drug and...

A vascular factor associates with plasma components in lung cancer patients.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- A vascular growth factor associates with plasma components in lung cancer patients. "Platelet activation, commonly found in lung cancer patients, may cause the release of angiogenic factors, such as...

The TT virus has been detected in children with acute respiratory disease.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- The TT virus has been detected in the nasal passages of children with acute respiratory disease. "The natural history and pathogenic potential of the recently identified TT virus (TTV) are...

Expression of Duffy antigen on alveolar septa is associated with infection.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Expression of Duffy antigen on alveolar septa is associated with infection. "Duffy antigen is a chemokine binding protein expressed on the surface of erythrocytes and postcapillary venular...

Refined colony-forming unit-megakaryocyte assay suitable for toxicologic testing.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- A modified version of the colony-forming unit-megakaryocyte assay (CFU-MK) is suitable for toxicological investigations. "In vitro colony-forming unit (CFU) assays can be used in the evaluation of...

Teen first ever to get experimental stem cell heart treatment.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Doctors at Beaumont Hospital in Royal Oak, Michigan, are first in the world to use stem cells from a patient's own blood to try to repair damage caused by a heart attack. The patient, 16-year-old...

CXCR4 cleavage may mediate progenitor cell mobilization.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Cleavage of the CXCR4 receptor on hematopoietic progenitor cells (HPCs) may mediate their mobilization by granulocyte colony-stimulating factor (G-CSF) and other agents. According to a study from...

Fludarabine with cyclophosphamide lowers GVHD risk in mice.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Fludarabine with cyclophosphamide lowers the graft-versus-host disease (GVHD) risk after hematopoietic stem cell transplantation in mice. GVHD "is a severe disorder and despite therapeutic efforts...

Low-dose donor lymphocyte infusions effective after haploidentical transplants.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Low-dose donor lymphocyte infusions can be effective after haploidentical stem cell transplants. "Haploidentical transplantation has become a clinical option for patients lacking a compatible...

Nonmyeloablative transplantation may be gonadotoxic.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Nonmyeloablative stem cell transplantation may have gonadotoxic side effects. "Most bone marrow transplant recipients are infertile due to reversible or irreversible testicular failure," explained...

Reduced-intensity conditioning widens transplant eligibility.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- A reduced-intensity conditioning regimen enables previously ineligible patients to undergo stem cell transplantation. "Toxicities of high-dose conditioning regimens have limited the use of...

Some chemotherapeutic agents alter regulation of thrombin on cell surfaces.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Some chemotherapeutic agents alter the regulation of thrombin on cell surfaces. According to a study from Canada, "Thromboembolic disorders are common in cancer patients. Two major contributing...

Recent observations of aggregation in collected blood to be studied.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- While extensive tests conducted by the U.S. Food and Drug Administration (FDA) as well as Baxter Healthcare Corporation have found no association between containers used in the collection of blood and...

OPTN/UNOS review of transplant error continues.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- The Organ Procurement and Transplant Network (OPTN), operated by the United Network for Organ Sharing (UNOS), continues to review the circumstances of a recent transplant for a patient whose blood type...

Genitourinary manifestations of hematologic diseases are becoming more common.
April 3, 2003... 2003 APR 3 - (NewsRx.com & NewsRx.net) -- Genitourinary manifestations of hematologic diseases are becoming more common. According to a study from the United States, "Hematologic disease encompasses a wide spectrum of disorders with a...

Chemistry of NO and HNO with heme proteins in different redox states studied.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Scientists with the National Cancer Institute, U.S. National Institutes of Health, delved into the chemistry of nitric oxide and nitroxyl with heme proteins in different redox states. ...

Complete compression ultrasonography valuable for diagnosis.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Complete compression ultrasonography is useful for diagnosing patients with suspected deep vein thrombosis. "Noninvasive diagnosis of deep vein thrombosis (DVT) is based on ultrasound examination...

Flow cytometry detects red blood cell-associated C3d better than tube agglutination assays.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Flow cytometry should be used to find erythrocyte-associated C3d. A recent study from the United States "compared flow cytometric analysis with tube agglutination assays for the detection of red...

Novel retinoid AHPN/CD437 induces rapid but incomplete apoptotic response.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- The novel synthetic retinoid AHPN/CD437 triggers a rapid, but incomplete apoptotic response in human myeloma cells. According to a recent study from France, AHPN/CD437 "appears to possess an...

Cryopreservation enhances cord blood stem cell viability.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Surprisingly, cryopreservation enhances the viability of stem cells in umbilical cord blood "Cordonal blood (CB) is today recognized as a potentially important source of hematopoietic stem cells...

D-dimer testing may predict recurrence.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- D-dimer testing may help identify patients at risk of recurrent venous thromboembolism. "The natural history of initially positive D-dimers for venous thromboembolism is not known," researchers in...

Novel cell line may aid study of p53 mutations.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- A novel acute leukemia cell line may aid the study of leukemia involving mutations in the p53 gene. Researchers in Japan "established and characterized a c-kit positive cell line from the bone...

Iron plus sulfadoxine-pyrimethamine best for anemia in children with malaria.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Intermittent preventive treatment with sulfadoxine-pyrimethamine and iron was most effective for treating anemia in children with malaria. According to recent research from the United States and...

Computer model developed for best conditions for velocity-driven AFP.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Computer model developed for best conditions for velocity-driven AFP. According to recent research from England, "Velocity-driven adiabatic fast passage (AFP) is commonly employed for perfusion...

New syndrome has recurrent infections followed by autoimmune neutropenia.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- New syndrome has recurrent infections followed by autoimmune neutropenia. "A new symptom-complex is described characterized by manifestations of autoimmune disease, infectious lymphadenopathy,...

Blood banks begin to screen donations for bacteria.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Ask about blood safety and most people think AIDS or other viruses that today are incredibly rare in transfusions. Bacterial contamination of blood poses a much bigger risk - sickening and killing...

ISBT 128 blood component labeling goes live with SafeTrace donor system.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Wyndgate Technologies, a division of Global Med Technologies, Inc., (GLOB), announced the implementation of its SafeTrace donor management system at St. Luke's Episcopal Health System in Houston,...

New data confirms therapeutic efficacy and safety of Intercept platelet system.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Recently published data demonstrates that physicians in Europe can safely provide their patients with the added security of pathogen-inactivated platelets while delivering the therapeutic benefits...

Cell surface markers fail to differentiate Th1 and Th2 cells.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Cell surface markers are not useful for distinguishing between type 1 and 2 immune cells in tuberculosis or other patients. According to a recent study from Mexico, "the aim of this work was to...

Adding a bone marrow clot to enriched bone matrix improves graft performance.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Adding a bone marrow clot to enriched bone matrix improves graft performance. "Bone marrow-derived cells including osteoblastic progenitors can be concentrated rapidly from bone marrow aspirates...

Imatinib mesylate treatment feasible for heavily pretreated patients.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Imantinib mesylate (STI571) treatment in feasible for heavily pretreated chronic myelogenous leukemia patients. Accordin to a recent study from Spain, STI571 "is a highly effective and...

Research grant awarded for AZ-Plasmin technology.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- CryoLife, Inc., (CRY) announced that AuraZyme Pharmaceuticals, Inc., a wholly owned subsidiary of the company, has recently been awarded a $100,000 research grant from the U.S. National Institutes of...

Single negative ultrasound sufficient to halt treatment.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- A single negative ultrasound is sufficient to halt treatment in potential deep-vein thrombosis patients. According to recent research from France, "in patients clinically suspected of deep-vein...

American Red Cross prepares to handle the unexpected.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- The American Red Cross is working with communities nationwide to make them safer from disaster through the "Together We Prepare" program. A multiplatform program, "Together We Prepare" encourages...

LOX-1 is a cell-adhesion molecule involved in leukocyte replacement.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- LOX-1 is a cell-adhesion molecule involved in leukocyte replacement. "Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a major endothelial receptor for oxidized low-density...

Biotech company announces change in auditors.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Cryo-Cell International, Inc., (CCEL) announced that on March 11, 2003, upon the recommendation and approval of its board of directors and its Audit Committee, Cryo-Cell engaged Ernst & Young, LLP to...

Arsenic trioxide enhances reverse transcription, blocks Ref1 antiviral activity.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- The antileukemia drug arsenic trioxide (As2O3) enhances retroviral reverse transcription, while blocking the activity of a key antiretroviral gene. "Potent drugs such as cyclosporine have provided...

Angiogenesis may play a role in the pathogenesis of hairy cell leukemia.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Angiogenesis may play a role in the pathogenesis of hairy cell leukemia. According to a study from Italy, "mMicrovessel density (MVD), a surrogate marker for angiogenesis, was evaluated by...

Good prospects reported for Aplidin in leukemia, lymphoma.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- PharmaMar announced at the 5th International Symposium on Leukemia and Lymphoma in Amsterdam, one of the most important international forums on blood malignancies, the first results indicating that...

Lipid rafts play key role in platelet signaling.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Lipid rafts play a key role in Fcgamma receptor IIa (FcgammaRIIa)-mediated platelet signaling. "The involvement of platelet FcgammaRIIa in heparin-associated thrombocytopenia (HIT) is now well...

The leap from plasmin to antiangiogenesis involves angiostatin production.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- The leap from plasmin to antiangiogenesis involves angiostatin production. According to a study from Greece, "plasmin is a broad-spectrum serine proteinase, which is presumed to cleave many...

Rockwell Medical Technologies signs supply contract with DaVita.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Rockwell Medical Technologies, Inc., (RMTI) a hemodialysis concentrate manufacturer, reported that it has signed a supply contract with DaVita, Inc., (DVA). Rockwell estimates that the supply...

Reduced neutrophil priming in women improves outcome.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Women have less extensive neutrophil priming during hemorrhagic shock, which results in better outcomes compared with their male counterparts. "Although gender influences T-cell, macrophage and...

Lymphocytes are not the best targets for treating lysosomal storage disease.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Lymphocytes are not the best targets for treating lysosomal storage disease. "Lymphocyte-directed gene transfer has been proposed as potential therapy to treat certain congenital immunological...

Location of TNFalpha and its receptors by cell type was determined in brain.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Location of TNFalpha and its receptors by cell type was determined in brain. A study from Poland "evaluated immunocytochemistry cellular localization and time-dependent expression of tumor necrosis...

Severe renal tubular acidosis can lead to repeated, acute kidney rejection.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Severe renal tubular acidosis can lead to repeated, acute kidney rejection. According to a study from South Korea, "Renal tubular acidosis in renal transplant recipients usually is asymptomatic and...

A rare leukemia type has certain genetic mutation and symptom characteristics.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- A rare type, minimally differentiated acute myeloblastic leukemia, has certain genetic mutation and symptom characteristics. According to recent research from France, "Mutations of the AML1 gene...

Mercuric chloride induces apoptosis through mitochondrial-dependent pathway.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Mercuric chloride induces apoptosis in leukemia cells through a mitochondrial-dependent pathway. "Mercurial compounds modulate immunologic functions by inducing cytotoxicity," researchers in Japan...

Erwinia L-asparaginase effective against recurrent natural killer/T-cell lymphoma.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Erwinia-derived L-asparaginase is effective against recurrent natural killer (NK)/T-cell lymphoma. Researchers in Japan described their experience with an (NK)/T-cell lymphoma patient "who...

Brain lesions may be diagnosed from angiomas as intravascular B cell lymphoma.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Brain lesions may be diagnosed from angiomas as intravascular B cell lymphoma. According to a study from Japan, "An 82-year-old man without notable medical history was admitted to our hospital...

Poor peripheral blood stem cell mobilization predicts poor outcome in autografted patients.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Poor peripheral blood stem cell mobilization predicts poor outcome in autografted lymphoma patients According to recent research from the United States, "the effect of poor blood stem cell...

Molecular stem cell graft contamination tests fail to predict outcome.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Molecular testing of stem cell autografts for contamination with malignant cells fails to predict the outcome of treatment in multiple myeloma patients. "To evaluate the clinical impact of minimal...

The nitric oxide synthase inhibitor L-NAME stalls angiogenesis in plasmacytoma.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- The nitric oxide synthase inhibitor L-NAME stalls angiogenesis in plasmacytoma. "Angiogenesis is a critical factors in sustaining the growth, invasion and metastasis of certain solid tumors and...

Anthracycline antibiotics target neovascularization and other functions.
April 10, 2003... 2003 APR 10 - (NewsRx.com & NewsRx.net) -- Anthracycline antibiotics target neovascularization and other functions. According to recent research from Japan, "anthracycline antibiotics are of particular value in the therapy of malignant...