Blood Weekly articles from April 2001

Blood Weekly archives from April 2001

Study Offers New Hope For Infants, Despite Mismatched Blood Types.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- Researchers at The Hospital for Sick Children, Toronto, Canada, have discovered that infant heart transplants can be performed safely and successfully despite major blood type incompatibility...

Anticoagulants Can Prevent Radiation-Induced Spinal Cord Damage.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers writing in the Annals of Pharmacotherapy report that anticoagulant therapy can reverse the symptoms of radiation-induced spinal cord damage. ...

Transfusion Study Shows Hepatitis G Prevalent In Brazil.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - The results of a Brazilian study show GB virus-C/hepatitis G virus (GBV-C/HGV) is highly prevalent in that country. Nevertheless, there is no evidence...

New Study To Investigate Chemokine Inhibitor's Role In Increasing White Blood Cells.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- AnorMED announced March 19, 2001, that it has initiated a new Phase I clinical trial in healthy volunteers to study the white blood cell count increasing effects of AMD-3100, an inhibitor of the...

Blood Thinner Demonstrates Potential Benefit Prior To Coronary Intervention.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- An analysis of more than 6,000 patients treated for acute coronary syndromes (unstable angina/non-ST segment elevation myocardial infarction), indicates that those who received the blood thinner...

Transplants Of Siblings' Cells Show Promise For Immune Disorder.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- U.S. National Institutes of Health (NIH) researchers in Bethesda, Maryland, have used a novel bone marrow transplantation procedure to successfully transfer stem cells from immunologically matched...

Progression From Myeloproliferative Disease To AML Studied.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers are using chimeric mice to study the mechanisms that cause myeloproliferative disease (MPD) and acute myeloid leukemia (AML). "Mice...

Trace Metal Assay Helps Prevent Poisoning In Joint Replacement Patients.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in England have developed a blood screen for trace metals used in joint replacement, which they say can help prevent metal poisoning in...

Outpatient Stem Cell Transplantation Carries Low Infection Risk.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Women who undergo outpatient stem cell transplantation after intensive chemotherapy have a reduced risk of infectious morbidity, oncologists report. ...

Recombinant Erythropoietin Treatment Not Linked To Thromboembolism.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Despite the concerns of some medical professionals, recombinant erythropoietin (rHuEpo) is not linked to dangerous hemostatic changes in patients with...

Biofeedback System Can Improve Blood Volume.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A biofeedback system that modulates dialysis variables based on blood volume measurements can safely improve dialysis-induced hypovolemia, researchers in...

Pre-Dialysis Hepatitis Virus Levels Influence Prevalence In Dialysis Units.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Pre-dialysis virus infection rates are a good indicator for overall virus prevalence in dialysis units, researchers say. Patients with chronic kidney...

European Union Grants Ribavirin Orphan-Drug Status Designation.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- ICN Pharmaceuticals, Inc. (ICN), announced March 16, 2001, that the European Commission has granted Orphan Drug Status designation in the European Union to intravenous ribavirin (Virazole) 100 mg/ml...

Proteinase K-Based Tests Best Choice For Parasite Detection.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Polymerase chain reaction (PCR) testing for visceral leishmaniasis (VL) is most accurate with proteinase K-based assays using buffy coat blood samples,...

Over 20 Clinical Trials Are Underway With Arsenic Trioxide.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- Cell Therapeutics, Inc. (CTIC) continues to advance the investigation of Trisenox (arsenic trioxide) injection in the treatment of a variety of blood-related cancers. Recently-initiated studies...

Overexpressed Proline-Directed Protein Kinase F-A Inhibits Growth Of Cancerous Cells.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers in Taiwan have found that inhibition of proline-directed protein kinase F-A expression inhibits leukemia cell growth. "Initial studies...

Stem Cells Can Reduce Intensified Chemotherapy Complications.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The side effects of aggressive chemotherapy for lung cancer can be reduced by supplementary treatment with blood progenitor cells, according to oncologists...

Patients Have Higher Morbidity Risk After Liver Transplantation.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Patients with portal vein thrombosis (PVT) have a higher risk of complications during and after liver transplantation, researchers in Spain warn. G....

Dead-Space And D-Dimer Assays Are Useful For Exclusion.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - D-dimer levels and alveolar dead-space measurements can be used to rule out pulmonary embolisms, say researchers in North Carolina. J.A. Kline and...

Fluorescent Visualization Can Determine Cytomegalovirus Susceptibility.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Fluorescent visualization techniques can be used after stem cell transplantation to quantify T-cell defenses against cytomegalovirus (CMV) infection,...

Technique Produces Cartilage Grafts For Ear Or Nasal Reconstruction.
April 5, 2001... 2001 APR 5 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Otorhinolaryngologists have successfully stimulated redifferentiation of auricular chondrocytes for use in ear and nasal cartilage reconstruction. ...

Many Hospitals Can Improve Infection Control.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Blood safety measures are too lax at many hospitals, putting health care workers at risk for dangerous infections, researchers writing in the journal...

Three Children Apparently Cured Through Unrelated Umbilical-Cord Blood Transplants.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- Physicians at the University of California, Los Angeles, announced on April 6, 2001, that three young boys - each born with a defective immune system like the "boy in the bubble" - underwent...

Pasteurized Clotting Factor Effective, Virus-Free.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - A current study reports Monoclate-P, a pasteurized factor VIII (FVIII) protein used for treating type A hemophiliacs, is effective and free of common...

Adult Stem Cell Injections In Mice Stimulate Blood Vessel Development.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- One of the most controversial issues in research today revolves around the potential medical use of stem cells derived from embryos. Britain has become the first country to approve research...

Hydroxyurea Improves Growth-Factor-Induced Hemoglobin Recovery.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Adding the DNA synthesis-inhibitor hydroxyurea to growth-factor-based therapy for sickle cell disease can improve hemoglobin recovery, researchers in...

Oxidative Detox Substances Can Predict Donor Morbidity.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Levels of substances involved in oxidative metabolism can help predict which stem cell donors will suffer morbidity or unsuccessful stem cell harvesting,...

Genetically Engineered Skin Substitute Designed.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- Bioengineers at the University at Buffalo, New York, and Shriners Burns Hospital, Boston, Massachusetts, have created a genetically engineered skin that expresses a protein that promotes wound...

Regulatory Proteins Can Disrupt DNA Repair.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - During HIV related lymphomas, the HIV regulatory protein Tat apparently alters the expression of the DNA polymerase (beta) ((beta)-pol) gene. Deepak K....

Drug Candidate Stimulates Neutrophil Production.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- Telik, Inc. (TELK) announced that additional data supporting the potential of its TLK199 product candidate were presented March 23, 2001, at the annual meeting of the American Association of Cancer...

Inflammatory Pain Can Increase Permeability.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Arizona have shown that inflammatory pain states can reduce the integrity of the blood-brain barrier, potentially altering medicine delivery...

Microvascular Growth Continues In Hearts Enlarged Due To Anemia.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Capillary neovascularization continues in hearts enlarged because of anemia, scientists say. The new vessel growth is advantageous for regulating blood...

Clonotypic Test Can Find Minimal Residual Disease.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in New York have developed an effective test for finding residual disease in chronic lymphocytic leukemia (CLL) patients in remission. ...

Hydroxychloroquine Can Kill Malignant B Cells.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Hydroxychloroquine, used to treat malaria and rheumatism, may also provide therapeutic benefit to B-chronic lymphocytic leukemia (B-CLL) patients, according...

Telomerase Activity In Peripheral Blood Mononuclear Cells Linked To Severity.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Telomerase activity in peripheral blood mononuclear cells (PBMCs) is linked to the presence and severity of systemic connective tissue diseases such as...

Teen Injection Drug Users In Dublin, Ireland, Practice High-Risk Behaviors.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Injection drug use by teenagers is on the rise in Dublin, Ireland, and causing young people, especially females, to participate in high-risk behaviors,...

Milder Chemo-Radiotherapy Regimen Reduces Toxicity.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A low-intensity regimen of combined chemo-radiation therapy for pediatric Hodgkin's disease reduces toxicity without sacrificing efficacy, researchers in...

Study Examines Outcomes Of Using Older Cadaveric Donors.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - With the increasing rise of chronic liver disease, the need for liver donors has become critical. A new study suggests livers from older cadaveric donors...

Anti-Platelet Agent Enhances Fibrinolytic's Ability To Bust Clots.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- Results announced March 18, 2001, at a symposium preceding the 50th Annual Scientific Session of the American College of Cardiology from a study of patients with ST-segment elevation myocardial...

Granulocyte-Macrophage Colony-Stimulating Factor Is Effective Prophylaxis.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Neutropenia caused by topotecan chemotherapy can be attenuated by pre-treatment priming with recombinant granulocyte-macrophage colony stimulating factor...

Filgrastim Effective As Part Of Oral Regimen For AIDS Patients.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The addition of oral filgrastim to chemotherapy for non-Hodgkin's lymphoma can improve the quality and duration of life for afflicted AIDS patients, study...

Hepatitis C Rate Among Health Care Workers In Lebanon Is Low.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - The hepatitis C virus infection rate among health care workers in Lebanon is the same as that of area blood donors, researchers at Arabian Gulf University...

Erythroid Lineage Markers May Point To Creutzfeldt-Jakob Disease.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Researchers working in Scotland have uncovered an early diagnostic marker for Creutzfeldt-Jakob disease, the human variation of bovine spongiform...

Serum-Free Expansion System Developed.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Japan have created a serum-free culture suitable for robust expansion of transplantable human blood progenitor cells. "In an attempt to...

Splenic Irradiation Is An Option For Patients With Autoimmune Disorders And Those With HIV.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Splenic irradiation can be used as an alternative treatment for patients with autoimmune blood disorders and patients infected with HIV, researchers in...

Recombinant Interleukin-11 Not Effective For Refractory Patients.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Despite its platelet-stimulating effects, recombinant human interleukin-11 (rhIL-11) does not show promising results for the treatment of refractory immune...

Plasma Glucosylceramide Deficiency Is Risk Factor.
April 12, 2001... 2001 APR 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Low levels of plasma glucosylceramide (GlcCer) are associated with an elevated risk of venous thrombosis, researchers warn. Hiroshi Deguchi and...

Routine PCR Testing Best For Detecting Early Hepatitis C Virus In Donated Blood.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Routine use of polymerase chain reaction (PCR) may be best for testing donor blood for hepatitis C virus (HCV), researchers in Germany indicate. Walter...

Pre-1990 Blood Products Most Likely To Infect Hemophiliacs With Hepatitis Viruses.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Males with hemophilia are more likely to acquire hepatitis C or B virus (HCV, HBV) infections from blood products made prior to 1990, U.S. Centers for...

Japanese Patients Have High Post-Transplant Lymphoma Rates.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Japanese patients who undergo kidney transplantation have a surprisingly high rate of postoperative lymphoproliferative disorders, which may result partly...

Scientists Determine Why Cells Stick, Causing Painful Crises.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- Despite recent advances in treating sickle cell disease, an inherited illness chiefly affecting black people in the United States, patients still suffer periodic painful episodes known as crises....

Stem Cell Transplantation Can Reverse Vascular Constriction.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Blood vessel narrowing induced by sickle cell disease can be reversed with donor-matched stem cell allografts, researchers at St. Jude Children's Hospital,...

Leukocyte Depletion Not Linked To Colorectal Cancer Recurrence, Reduced Survival.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Using leukocyte-depleted blood for colorectal cancer surgery transfusions has little effect on the associated risks, hematologists in The Netherlands...

Researchers Use Silicon Chips To Sustain Liver Cells In Mice.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- Scientists have coaxed liver cells into thriving on a specially machined silicon chip, a melding of biology and technology that could lead to the creation of artificial liver device that would...

Vitamin B-12 Helps Folic Acid Reduce Serum Homocysteine.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Sonia Bell-Nichols, staff medical writer - Vitamin B-12 enhances the effectiveness of folic acid when used for treating hemodialysis patients with hyperhomocysteinemia. Some studies have...

Polymer Gel Holds Promise For Therapeutics Delivery And Tissue Engineering.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- A new polymer-based material with unique gelling properties found useful in medical applications ranging from targeted cancer treatment to tissue engineering has been developed by researchers at...

Commonly Used Heparin-Coated Circuits Equally Effective.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The most widely-used heparin-coated coronary artery bypass circuits produce virtually identical results despite their functional differences, cardiologists...

Stem Cell Autografts May Enable Immunosuppression Holiday.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Pediatricians in Japan have shown that stem cell autotransplantation can allow juvenile rheumatoid arthritis (JRA) patients to escape the debilitating...

Preventing Hepatitis C Is A Factor In Stemming Organ Demand.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - A Stanford University researcher says preventing hepatitis C virus infections is just one of several ways to tackle the problem of too few livers for too...

Bone Disease Markers Can Help Predict At-Risk Patients.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Italy say that markers of levels of substances involved in bone metabolism can be used to identify multiple myeloma patients who are at risk...

Low-Dose Thalidomide Effective As Salvage Therapy.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Low doses of thalidomide can preserve its therapeutic effects for advanced multiple myeloma patients while reducing its toxicity, according to researchers...

Delayed Granulocyte Colony-Stimulating Factor Treatment Is Cost-Effective.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Late initiation of granulocyte colony-stimulating factor (G-CSF) therapy after stem cell transplantation for cancer treatment can markedly reduce the cost...

Gene Therapy Can Induce Host Immune Responses.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Inducing foreign protein expression in stem cells can lead to a robust and destructive immune response in their recipients, immunologists say. "Genetic...

High-Dose Mitoxantrone/Melphalan Regimen Safe, Effective.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A high-dose mitoxantrone/melphalan conditioning regimen for stem cell transplantation induces quick recovery with limited toxicity, researchers in Italy...

Intravenous Cell Transplant Holds Promise For Recovery.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- For the first time researchers have used bone marrow cells to reduce stroke-induced disability in rat experiments, according to a report in the April 2001 issue of Stroke. The study showed...

Recombinant Human Thrombopoietin Effective After Bone Marrow Transplantation.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Recombinant human thrombopoietin (rhTPO) can reverse the severe platelet deficiency that often follows bone marrow transplantation, researchers report. ...

HBV DNA-Positive, Antigen-Negative Blood May Not Be Infectious.
April 19, 2001... 2001 APR 19 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Blood that is hepatitis B virus (HBV) DNA-positive but surface antigen negative may not be infectious, researchers suggest. Alfred M. Prince, at the...

Ablative Preparative Therapy May Be Unnecessary For Newborns.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Bone marrow transplantation may be possible for newborns without using toxic and destructive preparatory regimens. "The toxicity of preparative...

Fetal Karyotyping Is Low-Risk Procedure.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The process of taking umbilical cord blood samples carries what researchers in Hungary have concluded is an acceptably low risk of fetal complications or...

Patients Face Risk Of Heart Attacks Soon After Stopping Heparin Use.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- Physicians have long known that patients face an increased short-term risk of having a heart attack after they stop taking anti-clotting medication. Now a new study reveals that patients using a...

Educational Materials Aid Patients In Making Pre-Surgery Decision.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- These patients are at increased risk of receiving any transfusion, however, which, in turn, increases their risk of acute hemolytic reaction due to human error and of infection due to bacterial...

Perflubron Emulsion Halves Number Of Blood Units Used In Surgeries.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- Alliance Pharmaceutical Corp. (ALLP) announced April 9, 2001, that the median number of units of blood required by study control patients was twice the median number of units of blood required by...

Coagulation Factor IX Expressed After Intraportal Administration.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Scientists at St. Jude Children's Research Hospital in Tennessee report that intraportal administration of coagulation factor IX expressing...

Multiple Blood Transfusions Can Increase Risk For Preterm Newborns.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Numerous blood transfusions may put premature neonates at risk for hepatic iron overload, caution pediatricians writing in the Archives of Disease in...

Researchers Transform Human Fat Into Bone, Muscle, Cartilage.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- The research team, which detailed the discovery in the April 2001 edition of the peer-reviewed journal Tissue Engineering, is the first to grow human tissue - bone, muscle, cartilage, and fat -...

Tumor Necrosis Factor Binding Protein Ineffective For Stem Cell Recovery.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A soluble tumor necrosis factor (TNF) receptor does not produce significant hematopoietic recovery in HIV patients, despite promising results from in vitro...

Farnesyl Transferase Inhibitors May Prevent Early Disease Progression.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Drugs that block the effects of farnesyl transferase may be able to prevent acute lymphoblastic leukemia (ALL) progression in patients with a dangerous...

Osteopontin Required For Bone Resorption, Neovascularization.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Scientists say that osteopontin, a protein produced by osteoclasts, is required for efficient bone resorption and neovascularization. "Osteopontin is...

Socioeconomics A Factor In TT Virus And Hepatitis A In Brazil.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Education levels and finances may influence the prevalence of TT virus (TTV) and hepatitis A virus (HAV) among some sectors of Brazilian society. TTV,...

Maternal Thrombotic Mutations Linked To Infants' Low Birthweight.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Women with genetic mutations known to be prothrombotic risk factors are at increased risk of having children with fetal growth restriction (FGR), according...

Egr-1 Stimulates Macrophage Progenitors.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers at Temple University in Pennsylvania found that expression of the early growth response gene 1 (Egr-1) in bone marrow cultures results in...

Nature Of HCV infections Acquired At Brazilian Center Analyzed.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Researchers in Brazil have determined five hemodialysis patients acquired hepatitis C virus (HCV) at the same center, even though their HCV antibody tests...

Interferon-(gamma) Therapy Ineffective.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Despite theoretical promise, researchers in Austria say that interferon (IFN)-(gamma) does not provide significant benefit to idiopathic myelofibrosis...

African Americans Retain Immune Response While On Immunosuppressive Drugs.
April 26, 2001... 2001 APR 26 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Despite the use of immunosuppressive therapies after liver and kidney transplants, African Americans suffer worse graft survival rates than white patients....