Immunotherapy Weekly articles from October 2004

Immunotherapy Weekly archives from October 2004

DNA vaccine reverses allergic airway inflammation and eosinophilia.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Reversal of established CD4+ type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and...

Side effects greater with aqueous than depot therapy for bee venom allergy.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Early local side effects occur at higher frequency with aqueous than with depot immunotherapy for Hymenoptera venom allergy. "Venom immunotherapy has proven a very effective method for the...

CV capacity, quadriceps muscle strength play modest role in rapid walking.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A recent study examined associations between walking time, quadriceps muscle strength and cardiovascular capacity in patients with rheumatoid arthritis and ankylosing spondylitis. According to the...

GD3-L-KLH vaccine elicits antibody response in melanoma patients.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Sequential immunization of melanoma patients with GD3 ganglioside vaccine and anti-idiotypic monoclonal antibody that mimics GD3 ganglioside elicited an antibody response that did not correlate with...

Role of CD8+ T-cell immunity in progression of melanoma reviewed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers review the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients in a recent issue of Clinical Cancer Research. According to...

Gag CTL-positive vaccinees recipients do not have anti-gag p17 response.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele did not exhibit immunodominant anti-gag p17 (SL9) responses. According to recent research published in the...

HIV vaccine combination safe and immunogenic in HIV-negative adults.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- An HIV subtype B and E prime-boost vaccine combination was safe and immunogenic in HIV-negative Thai adults. "ALVAC-HIV (vCP1521) and AIDSVAX B/E were evaluated in a phase 1/2 trial of human...

Heat shock protein mediates cross-presentation of exogenous HIV antigen.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Heat shock protein mediates cross-presentation of exogenous HIV antigen on HLA class I and class II. According to a study from the United States, "Strong CD4+ and CD8+ T cell responses are...

Immune responses to hemagglutinin/SHIV-like particle vaccine reported.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists report Th cell-independent immune responses to a chimeric hemagglutinin/simian human immunodeficiency virus-like particle vaccine. "CD4+ Th cells are believed to be essential for the...

Immunization with Listeria controls virus load after FIV challenge.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Oral immunization with recombinant Listeria monocytogenes controls virus load after vaginal challenge with feline immunodeficiency virus. "Recombinant Listeria monocytogenes has many attractive...

Methods to monitor oligomeric state of HIV vaccine antigen evaluated.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers have evaluated on-line high-performance size-exclusion chromatography, differential refractometry, and multi-angle laser light scattering analysis for the monitoring of the oligomeric state...

Papillomavirus-HIV-1 gp41 virus-like particles induce HIV antibodies.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Oral immunization with bovine papillomavirus-HIV-1 gp41 chimeric virus-like particles induced mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1). ...

Plasmacytoid dendritic cell activation augments SIV-specific T cells.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques augments the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T...

Recruiting London gay men into HIV vaccine trial is feasible.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Recruiting London gay men into an HIV vaccine trial is feasible. "This paper describes a study among HIV-negative gay men in London to examine willingness to volunteer for an HIV vaccine trial....

Screening for HIV-specific T-cell responses recommended.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers recommend screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes. "The IFN-gamma enzyme-linked immunospot (ELISpot) assay is often used...

Paper describes new treatment for prevention of postsurgical adhesions.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- ARC Pharmaceuticals, Inc., announced that Dr. Johanne Cashman, director of preclinical research, published a paper entitled "Camptothecin-loaded Films for the Prevention of Postsurgical Adhesions" in...

Food Allergy Buddy dining card launched.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Philip Lempert, known by both consumers and the food industry as the "Supermarket Guru" and an expert analyst on consumer, marketing and food safety trends, announced the launch of the Food Allergy...

Drug in phase 2 clinical trial for patients suffering from peanut allergy.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Tanox, Inc. (TNOX) announced that the first patient has been enrolled in a phase 2 clinical trial evaluating the safety and efficacy of Xolair (omalizumab) in patients suffering from allergy (immediate...

S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective. According to recent research from Canada, "The protective effects of non-steroidal anti-inflammatory drugs (NSAIDs) in...

Animal models are guiding development of new immunotherapies for cancer.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Animal models are guiding the development of new immunotherapies for cancer. According to recent research published in the Journal of Leukocyte Biology, "Immunotherapy using adoptive cell transfer...

In vitro-based potency assay for anthrax vaccine developed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists have developed an in vitro-based potency assay for anthrax vaccines. According to recent research published in the journal Vaccine, "The potency assay currently used to evaluate...

Streptococcolytic enzyme zoocin A is a penicillin-binding protein.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Streptococcolytic enzyme zoocin A is a penicillin-binding protein. "Zoocin A is a streptococcolytic enzyme produced by Streptococcus equi subsp. zooepidemicus 4881 that has an unknown site of...

Novel antifungal protein from gold kiwi fruit active against Fusarium oxysporum.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel antifungal protein from the gold kiwi fruit is active against Fusarium oxysporum. "An antifungal protein designated actinchinin, with an N-terminal sequence different from that of the...

Two-thirds of prescription antihistamine users test negative for allergies.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A new study in the current issue of Journal of Managed Care Pharmacy concludes that 62% of frequent antihistamine users did not test positive for allergies. The authors recommend that objective...

Novel podophyllotoxin derivatives have anti-HIV activity.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Novel podophyllotoxin derivatives have anti-HIV activity. According to recent research from the United States, "A series of novel podophyllotoxin derivatives containing structural modifications at...

Recommendations made for two versus three drugs for postexposure HIV prophylaxis.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Recommendations are made for two versus three drugs for postexposure HIV prophylaxis. "Thousands of health care workers are potentially exposed to human immunodeficiency virus (HIV) each year via...

Inhibition of nitric oxide synthase exacerbates GBS sepsis, arthritis in mice.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Inhibition of nitric oxide synthase exacerbates GBS sepsis and arthritis in mice. Researchers from Italy reported, "The role of nitric oxide in group B Streptococcus (GBS) infection was evaluated by...

Hand-held device measures airway inflammation.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Clinical data on a new first-of-a-kind hand-held analyser of inflammation in asthma patients, Niox Mino, were presented for the first time on September 5, 2004, at the European Respiratory Society (ERS)...

IFN-gamma induces apoptosis in allergen-activated T cells.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- IFN-gamma induces apoptosis in allergen-activated T cells from atopic asthma patients. "The defect in interferon-gamma (IFN-gamma) production that results in a T helper cell type 2-dominated...

Injected corticosteroids reduce eosinophilic airway inflammation.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- In a study of patients with severe asthma who had eosinophils in their sputum despite extensive antiasthma medication, investigators showed that a high dose of extra intra-muscular corticosteroids...

Potential asthma monoclonal antibody to enter phase I clinical trial.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology (CATG) will be starting a phase I clinical trial of CAT-354, a human anti-IL-13 monoclonal antibody, which is a potential treatment for severe asthma, following recent...

Regular sustained combination therapy may reduce asthma exacerbations.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- New data presented at the 14th annual European Respiratory Society (ERS) Congress in Glasgow have revealed the results of the EXCEL (EXacerbation Control Evaluated in a 6 month Long) study, a head to...

Scientists discover link between serotonin and airway allergic inflammation.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists at the La Jolla Institute for Molecular Medicine (LJIMM) have discovered that serotonin, a naturally occurring neurotransmitter that is elevated in the blood of asthmatics, can directly cause...

Understanding biology of AT can lead to greater knowledge of its underlying processes.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Ataxia telangiectasia (AT) causes a variety of problems and results from defects in the response to specific types of DNA damage, researchers say. According to a study from the United States,...

Anti-atherosclerosis polypeptide vaccine expressed in E. coli.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists have expressed an anti-atherosclerosis polypeptide vaccine in Escherichia coli. According to recent research from China, "A chimeric polypeptide of TTP-CETPC was successfully expressed...

Listeria monocytogenes composed of at least three evolutionary lineages.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Listeria monocytogenes is composed of at least three evolutionary lineages. According to published research from the United States, "Listeria monocytogenes is a serious food-borne pathogen that can...

Multidrug-resistant S. enterica serovar Typhimurium found in shellfish in Spain.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Multidrug-resistant Salmonella enterica serovar Typhimurium was found in shellfish off the coast of Spain. "Twenty-three Salmonella enterica serovar Typhimurium isolates from marine environments...

L. monocytogenes in biofilms controlled by competitive-exclusion microorganisms.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Listeria monocytogenes in biofilms are controlled by competitive-exclusion microorganisms. "Biofilms from drains in food processing facilities with a recent history of no detectable Listeria...

Bacterial resistance increased from 1998 to 2002 in hospital in Slovakia.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Bacterial resistance increased from 1998 to 2002 in a hospital in Slovakia. According investigators in Slovakia, "The purpose of this study was to analyze the resistance during the period of...

Community MSRA isolates in Australia belong to five CHEF electrophoretic patterns.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Community methicillin-resistant Staphylococcus aureus isolates in Australia belong to five contour-clamped homogeneous electric field electrophoretic patterns. According to a study from Australia,...

MRSA strains susceptible to aminoglycosides genotyped.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- MRSA strains susceptible to aminoglycosides were genotyped. According to a study from France, "Methicillin-resistant Staphylococcus aureus (MRSA) susceptible strains to aminoglycosides (AS-MRSA)...

astA gene transposed into prophage of S. enterica serovar abortusovis.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Heat-stabile toxin astA gene was transposed into the prophage of Salmonella enterica serovar abortusovis. "The horizontal transfer and acquisition of virulence genes via mobile genetic elements...

Heat-shock proteins and host-pathogen interactions reviewed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Scientists review heat-shock proteins and the host-pathogen interaction during bacterial infection in a recent issue of Current Opinion in Immunology. "Heat-shock proteins (HSPs) are expressed at...

Comparative study released on superficial papillary urothelial carcinomas.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Superficial papillary urothelial carcinomas in 'young' patients had a better prognosis than those in the 'elderly' group, according to new research. According to a study from Italy, "To compare the...

Profile of continuous antigenic regions of botulinum H-chain reported.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers present the full profile of the continuous antigenic regions of the H-chain of botulinum neurotoxin A in a recent issue of the Protein Journal. According to recent research from the...

Biologic therapy for brain cancers reviewed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A reseracher reviews biologic therapy for brain cancers in a recent issue of the Yonsei Medical Journal. According to a study from the United States, "The overall goal of our research projects is...

Silicone induces strong local T-cell immune response.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Silicone in breast implants induces a strong local response by T lymphocytes, but why this is remains unclear. "During the past 30 years, much debate has centered around side effects of silicone...

Novel tumor antigen may be useful in osteosarcoma immunotherapy.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel tumor antigen may be useful in osteosarcoma immunotherapy. According to recent research from Japan, the "prognosis for patients with osteosarcoma who do not respond to current chemotherapy...

Antibodies in tumor immunotherapy reviewed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers review antibodies in tumor immunotherapy in a recent issue of Expert Opinion on Biological Therapy. "The role of antibodies as therapeutic cancer vaccines includes two distinct...

Dendritic cell-based immunotherapy for cancer reviewed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers review dendritic cell-based immunotherapy for cancer in a recent issue of Transfusion Medicine Reviews. According to recent research from the United States, "The encouraging results...

Gene-engineered T cells are superior adjuvant therapy for cancer.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Gene-engineered T cells are a superior adjuvant therapy for metastatic cancer. According to a study from Australia, "The major limiting factor in the successful application of adjuvant therapy for...

Heat shock proteins reviewed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers review heat shock proteins in a recent issue of Immunology Letters. "The contribution of major histocompatibility complex (MHC) I and II to the adaptive immune response has been well...

Strategies to improve dendritic cell cancer immunotherapy outlined.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers outline strategies to improve dendritic cell-based immunotherapy against cancer in a recent issue of the Yonsei Medical Journal. "Dendritic cells (DCs) play a pivotal role in T...

Ubiquitin-fusion degradation pathway plays key role in DNA vaccination.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- The ubiquitin-fusion degradation pathway plays an indispensable role in naked DNA vaccination with a chimeric gene encoding a syngeneic cytotoxic T lymphocyte epitope of melanocyte and green fluorescent...

Yeast-based immunotherapy causes mutation-selective tumor remission.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Ras-targeted, whole yeast-based immunotherapy resulted in mutation-selective tumor remission. "Activating mutations in Ras oncoproteins represent attractive targets for cancer immunotherapy, but...

Alemtuzumab may have a role in inducing important cardiac side effects.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Cardiac toxicity of alemtuzumab in patients with mycosis fungoides/Sezary syndrome "Alemtuzumab is a monoclonal antibody to CD52 that has activity in T-cell leukemia and lymphoma. This study alms to...

Rashes from Oka vaccine are derived from single clones of virus.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Rashes occurring after immunization with a mixture of viruses in the Oka vaccine are derived from single clones of the virus. According to recent research published in the Journal of Infectious...

Clinical trials of drug for internal genital warts broadened.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Stressgen Biotechnologies (SSB) announced that it has broadened the clinical program for its lead drug candidate, HspE7. The company has expanded the program through the enrollment of patients in a...

Companies to commence second phase III trial for milnacipran in Q4.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Cypress Bioscience, Inc., (CYPB) expects its partner, Forest Laboratories (FRX) to initiate the second phase III trial evaluating milnacipran for the treatment of fibromyalgia syndrome (FMS) during the...

Strategic biopharm research, development and commercialization alliance formed.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- ZymoGenetics, Inc. (ZGEN) and Serono (SRA) announced their intent to enter into a broad partnership to research, develop and commercialize protein and antibody therapeutics based on discoveries made by...

Diagnostics company enters broad diagnostic collaboration with Compugen.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Diagnostic Products Corp. (DP) and Compugen, Ltd., (CGEN) announced a broad collaboration for the development and commercialization of novel diagnostic products, with an anticipated focus in the cancer...

Strong association of ARK5 with tumor invasion and metastasis.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- There is a strong association of ARK5 with tumor invasion and metastasis. According to a study from Japan, "We recently identified a novel human AMPK family member, ARK5, and discovered that is a...

Cocaine- and amphetamine-regulated transcript stimulates colonic motility.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Cocaine- and amphetamine-regulated transcript stimulates colonic motility via central CRF receptor activation and peripheral cholinergic pathways in fed, conscious rats. "Many neuropeptides...

PX3.102 appears to diminish chronic airway allograft rejection.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- PX3.102 appears to diminish chronic airway allograft rejection. According to a study from the United States, "More effective immunosuppressants are needed to improve lung-transplantation survival....

Efficacy of dendritic cell-induced tolerance dependent on delivery path.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- The efficacy of peripheral tolerance induced by dendritic cells is dependent on the route of delivery. "Previous studies have demonstrated that the route of delivery of dendritic cells (DC) is an...

Phase 2a trial results reported for investigational drug in atopic dermatitis.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Nucryst Pharmaceuticals Corp., a subsidiary of The Westaim Corporation, announced results from its initial phase 2a efficacy and safety study of NPI 32101 in a cream formulation in adult patients with...

BNP can be used to differentiate causes of respiratory distress in children.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- B-type natriuretic peptide has utility in differentiating congestive heart failure from lung disease in pediatric patients with respiratory distress. According to a study from the United States,...

Minimal residual disease assessment predicts survival and relapse in AML.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Minimal residual disease assessment predicts survival and relapse in acute myeloid leukemia. "Outgrowth of minimal residual disease (MRD) in acute myeloid leukemia (AML) is responsible for the...

Zinc deficiency impairs immune function and resistance to infection.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Zinc deficiency impairs immune function and resistance to infection. "Zinc is an essential micronutrient for human growth, development, and immune function. Zinc deficiency impairs overall immune...

Aprotinin injection during artery bypass graft surgery may reduce risk of stroke.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Trasylol (aprotinin injection) therapy is associated with a 47% relative risk reduction for stroke in patients undergoing coronary artery bypass graft (CABG) surgery, according to a study published in...

Collaboration agreement signed for development of non-antibody protein.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Nautilus Biotech SA and Creabilis Therapeutics SRL signed a collaboration agreement for the identification and development of an improved variant of CT500, a non-antibody protein selected by Creabilis...

Cultivation of fetal human hepatocytes attempted in microfluidic environment.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Cultivation of fetal human hepatocytes was attempted in a microfluidic environment. "Various types of bioreactors composed of microstructured PDMS (Polydimethylsiloxane) layers have recently been...

Noncommitted neuroectodermal SCs integrate into brain during tissue genesis.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Noncommitted neuroectodermal stem cells integrate into the brain during or at the time of tissue genesis. "NE-4C, one-cell derived neuroectodermal stem cells expressing a reporter gene-green...

Src family of tyrosine kinases important for embryonic stem cell self-renewal.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. "cYes, a member of the Src family of non-receptor tyrosine kinases, is highly expressed in mouse and human...

Microparticle encephalitis vaccine elicits mixed immmune response.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A cationic microparticle-adsorbed plasmid DNA encoding Japanese encephalitis virus envelope protein is immunogenic in mice. "Previously, we described a plasmid pMEa, synthesizing the anchored form...

Chemokine receptor plays key role in pathogenesis of encephalomyelitis.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- The CXC chemokine ligand 16/scavenger receptor that binds phosphatidylserine and oxidized lipoprotein plays a critical role in the pathogenesis of both acute and adoptive transfer experimental...

Enteroviral meningitis outbreak in France is caused by human echovirus 30.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- An enteroviral meningitis outbreak in France is caused by human echovirus 30. According to recent research from France, "Enteroviruses (EVs) are responsible for an array of clinical diseases...

Enterovirus 71 strain causes neurological disease after oral infection.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Enterovirus 71 strain causes neurological disease after oral infection. "A mouse-adapted enterovirus 71 (EV71) strain with increased virulence in mice, MP4, was generated after four serial passages...

Mutation identified as molecular basis of congenital coagulation FXII deficiency.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel mutation is identified as a molecular basis of congenital coagulation Factor XII deficiency. According to a study from Japan, the "factor XII (FXII) gene of a patient with congenital FXII...

Immune-focused company closes $6.4M in second round of private financing.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- Cylex, Inc., a life sciences company with a focus on immune system testing, announced that it has successfully closed its second round of private financing at $6.4 million. The company, which was...

Pharmaceutical company closes on $30M Series B financing.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- MAP Pharmaceuticals, Inc., announced the closing of a $30 million Series B preferred stock financing. Proceeds from this financing will be used primarily to advance the clinical development of the...

Natural saline nasal wash released to help airline passengers fight cabin germs.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- One in every 5 people get a cold after an airline flight, the relative humidity of in-flight cabins falls somewhere below 20%, and many passengers struggle to find "good" air at 35,000 feet. Xlear,...

PCR identifies enterotoxigenic S. aureus strains from food poisoning outbreaks.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- A PCR assay identifies enterotoxigenic Staphylococcus aureus strains from food poisoning outbreaks. "Three food poisoning restaurant outbreaks due to Staphylococcus aureus, occurring during...

Pediatric company acquires Protein Therapeutics.
October 6, 2004... 2004 OCT 6 - (NewsRx.com & NewsRx.net) -- PediaMed - The Pediatrics Company announced that it has acquired Protein Therapeutics. The acquisition includes an investigational immunoglobulin drug that is entering phase II clinical trials for...