Immunotherapy Weekly articles from October 2002

Immunotherapy Weekly archives from October 2002

Involuntary smoke exposure affects asthma severity in children.
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Children with high levels of tobacco smoke exposure are more likely to have moderate or severe asthma, according to a study conducted by the Centers for Disease Control and Prevention. While it has...

Immune cell's dramatic rescue efforts caught on tape.
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Researchers at Yale University and the Ludwig Institute for Cancer Research have captured on video the rather difficult journey a group of immune stimulating molecules go through to warn the body of...

Further evidence of increase in allergic disease in Western countries.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Danish authors of a research letter in the August 31, 2002, issue of the Lancet provide further evidence to suggest that allergic diseases are becoming increasingly common in western populations. ...

Survey: Americans underestimate the consequences of allergies.
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Ninety-four percent of allergy sufferers report in a recent survey that their quality of life, often including their work productivity, sleep, concentration, and even their sex lives, is affected by...

Study: Pimecrolimus significantly modifies course of skin disease in infants.(atopic eczema)(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Treatment of the early symptoms of the itching skin disease, atopic eczema, with the new nonsteroid cream Elidel (pimecrolimus) significantly modifies the disease course in infants by reducing the...

Lumenis ClearLight receives FDA clearance.(acne treatment system)(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Lumenis, Ltd., (LUME) announced that the U.S. Food and Drug Administration (FDA) has granted 510(K) clearance to the first acne treatment device for moderate inflammatory acne vulgaris. The...

Positive results announced in phase II clinical trial of INS37217.(Inspire Pharmaceuticals Inc. announces results of allergic rhinitis treatment trial)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Inspire Pharmaceuticals, Inc., (ISPH) announced that results of a phase II clinical trial for INS37217 Intranasal in patients with perennial allergic rhinitis (PAR). INS37217 demonstrated...

Collaboration expanded for target characterization, drug discovery.(Cambridge Antibody Technology and Xerion Pharmaceuticals AG expand research agreement)(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology (CATG; CAT) and Xerion Pharmaceuticals AG announced the expansion of their existing business relationship into a research collaboration for target characterization and drug...

Common foods worsen hayfever symptoms, pose danger in some patients, doctors say.
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Hayfever sufferers know all too well the miseries of the late-summer ragweed season: runny nose, sneezing and itchy, watery eyes. What most don't know is that among some people allergic to ragweed,...

Introduction of generic Claritin will reduce antihistamine market.(loratadine from Schering-Plough)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, announced that the introduction of generic forms of Claritin...

Drug discovery company hires regulatory affairs director, gears up for clinical trials by year end.(Paratek Pharmaceuticals Inc.)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Paratek Pharmaceuticals, Inc., announced the appointment of Donna Supko, PhD, as director of regulatory affairs. Supko will be responsible for coordinating the regulatory process for Paratek's lead...

Merckle invests in Ascentia Pharma.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Merckle GmbH (Germany) has acquired $3,000,000 of treasury shares in the Canadian pharmaceutical company Ascentia Pharma, Inc., a wholly owned subsidiary of Horizon Sciences & Technology. The...

MorphoSys announces first milestone in Centocor antibody collaboration.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- MorphoSys AG (MOR), the Munich-based biotechnology company, announced the achievement of a first milestone in its therapeutic antibody cooperation with Centocor, Inc. MorphoSys receives an...

Anticancer drug developer announces second quarter 2002 financial results.(NeoPharm Inc.)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- NeoPharm, Inc., (NEOL) announced financial results for the second quarter of 2002. The company reported a net loss of $9,019,674 or $0.55 per share, basic and diluted, for the second quarter 2002...

Genomics-based drug discovery company shows 2Q 2002 net loss: $0.36 per share.(Genome Therapeutics Corp.)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Genome Therapeutics Corp. (GENE) released financial results for the second quarter ended June 29, 2002. In line with prior guidance, the company reported a net loss for the quarter of $8,317,000,...

Type I interferon gene therapy protects against CMV-induced condition.(cytomegalovirus )
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Researchers in Australia have reported on the efficacy of seven interferon subtypes in DNA gene therapy against cytomegalovirus-induced myocarditis. "Type I interferons (IFNs) are produced early in...

GlaxoSmithKline buys protein profiling biochip system.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Zyomyx, Inc., a leader in protein biochip technologies, announced that GlaxoSmithKline (GSK) has become an early technology access customer for its Protein Profiling Biochip System, human cytokine...

R&DAbs gets patent allowance for sepsis and rheumatoid arthritis diagnostics.(Research & Diagnostic Antibodies)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Research & Diagnostic Antibodies (R&DAbs) announced the allowance of a U.S. patent for a panel of monoclonal antibodies and immunoassays that detect human iNOS (inducible Nitric Oxide Synthase). ...

Cured of immune disorder, Dutch boy leaves protective bubble.(Wilco Conradi, severe combined immunodeficiency)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- The remnants of lunch were on Wilco Conradi's rosy cheeks when the 2-year-old grabbed a large ice cream and ran back to the table. "Let's see if this tastes OK," he said, climbing onto his mother's...

Islet cell transplantation for diabetes has more widespread success.
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- More diabetic patients are coming off insulin following pancreatic islet cell transplantation than ever before, according to multiple studies presented at the XIX International Congress of The...

Altered-peptide ligand has therapeutic activity.
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- An altered-peptide ligand from an islet beta-cell-specific antigen in type 1 diabetes has been found to have therapeutic activity, report scientists at Neurocrine Bioscience Inc., California, USA. ...

Cat exposure increases risk for children of asthmatic mothers.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Scientists are gaining a better understanding of the complex relationship between cat exposure and the risk of developing asthma. For many years, scientists thought that cat exposure increased a...

Isolated human antibodies could protect against Shiga toxin effects.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have developed a novel approach to treating conditions caused by the microbial Shiga toxin. "Hemolytic-uremic syndrome...

New study combines Prograf with Rapamune or CellCept.(tacrolimus, sirolimus, and/or mycophenolate mofetil for transplant immunosuppression)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Results of a clinical study combining Prograf (tacrolimus)-based immunosuppression with Rapamune (sirolimus) or CellCept (mycophenolate mofetil) were presented at the XIX International Congress of the...

More hand transplants to be performed, predict experts.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Although since the world's first hand transplant in 1998 there have been just 11 additional cases, results presented at the XIX International Congress of the Transplantation Society indicate the...

Transplants in HIV patients should proceed, but drug interactions a concern.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- While historically surgeons have been reluctant to transplant patients with the human immunodeficiency virus (HIV), in recent years some centers have begun to accept patients with well-controlled HIV as...

Study vaccine ineffective against cypress pollen allergy.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- An attempt to develop a vaccine for cypress pollen allergy did not yield a sucessful immunotherapy, researchers in France report. "Cupressaceae pollen allergy is a world-wide pollenosis but...

FDA accepts Zyvox for review.(Pharmacia Corp. )(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Pharmacia Corp. (PHA) announced that the U.S. Food and Drug Administration (FDA) has accepted for review the supplemental new drug application (sNDA) of Zyvox (linezolid injection, tablets and for oral...

'Naked DNA Company' expands management team.(Vical Inc.)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Vical, Inc., (VICL) announced the expansion of its management team with the appointment of Alain P. Rolland, PharmD, PhD, as vice president, product development, and the appointment of Thomas G. Evans,...

VP of corporate development added to implement licensing strategy.(AVANIR Pharmaceuticals appoints Martin Emanuele)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Avanir Pharmaceuticals (AVN), a biopharmaceutical drug discovery and development company with a commercialized FDA-approved product on the market, announced that Martin Emanuele, PhD, has joined the...

Single-step technology enables synthesis of cyclosporin.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Enanta Pharmaceuticals, Inc., presented its proprietary single-step chemistry technology that enables synthesis of novel cyclosporin A softdrug analogs as potential asthma therapeutics. The...

Genetic evidence for IL-6 in experimental autoimmune myasthenia gravis found.(interleukin-6)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- University of Texas researchers have elucidated the role of interleukin-6 in experimental autoimmune myasthenia gravis. C.S. Deng and colleagues immunized "IL-6 gene KO (IL-6(-/-)) mice in the...

Murine study describes pathology, self-antigen response in autoimmunity.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- According to recent research from Taiwan, "One of the hallmarks of systemic autoimmune diseases, such as systemic lupus erythematosus (SLE), is the immune response to nuclear autoantigens. Several...

Study emphasizes importance of genetic susceptibility to autoimmunity.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Genetic background, rheumatologists report, plays an important role in susceptibility to autoimmunity. "In previous studies we have established a link between cytomegalovirus (CMV) infection and an...

Finger-stick test launched.(cdSCAN celiac disease diagnostic test from York Nutritional Laboratories)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- cdSCAN, the latest innovation in the screening for celiac disease (CD), has been developed by York Nutritional Laboratories. With only 1 out of 80 of the projected 1 million individuals in this...

Snake venom antibodies produced in chicken egg yolk.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Researchers in India have developed a simple way to produce antivenom immunoglobulins in chicken egg yolk. They published their report in the journal Toxicon. "The therapeutic use of specific...

Study: Benefits obtained from 'finger-stick' food intolerance test.(IgG ELISA food intolerance test from York Nutritional Laboratories)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- The medical journal, The Townsend Letter for Doctors and Patients, recently published an independent audit conducted by the Department of Health Studies at the University of York, on behalf of the...

Patent issued for dendritic cell activation.(to Coley Pharmaceutical Group Inc.)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- The U.S. Patent and Trademark Office has granted U.S. Patent No. 6,429,199, the 10th patent owned by or exclusively licensed to Coley Pharmaceutical Group, Inc., This patent covers the use of CpG...

Letter of intent for potential investment announced.(HemispheRx BioPharma receives letter from the Royal Family of the United Arab Emirates)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- HemispheRx BioPharma has received a letter of intent for a potential multimillion-dollar investment in the company by the Royal Family of the United Arab Emirates. HemispheRx president and CEO...

U.S. patent granted for TAP-1 against all cancers.(GeneMax Corp. receives patent for transporters associated with antigen processing cancer therapy)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- GeneMax Corp. (GMXX; GX1) announced that it has received in the first quarter of 2002, a U.S. patent for the use of TAP-1 (transporters associated with antigen processing) as an immunotherapy against...

MedImmune responds to FluMist complete response letter.(intranasal influenza virus vaccine)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- MedImmune, Inc., (MEDI) announced that it has completed the submission of information requested by the U.S. Food and Drug Administration (FDA) for FluMist (influenza virus vaccine live, intranasal), a...

Patient recruitment, enrollment completed for Therafab.(Antisoma PLC)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Antisoma, the U.K.-based biopharmaceutical company developing new drugs for cancer, has completed recruitment into a phase I trial of its radiolabeled monoclonal antibody fragment, TheraFab. The...

Sicor wins ANDA approval for Promethazine Hydrochloride Injection.(Gensia Sicor Pharmaceuticals Inc. receives abbreviated new drug application )(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Sicor, Inc., (SCRI) announced that its wholly owned subsidiary, Gensia Sicor Pharmaceuticals, Inc., received approval of an abbreviated new drug application (ANDA) from the U.S. Food and Drug...

Carbohydrates in cartilage may be antigen for RA.(rheumatoid arthritis)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Researchers presented findings at the American Chemical Society's national meeting reporting that naturally occurring carbohydrates in cartilage may be an important antigen in rheumatoid arthritis (RA)....

Joint venture with Deseret Laboratories announced.(AutoImmune Inc. to form Colloral L.L.C. with Deseret Laboratories International)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- AutoImmune, Inc., (AIMM) announced the formation of Colloral LLC, a joint venture with Deseret Laboratories International (a private company headquartered in St. George, Utah) for the manufacture,...

Sepracor announces copromotion agreement for antihistamine product Astelin.(MedPointe Inc. and Sepracor Inc. to market azelastine HCL nasal spray)(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Sepracor, Inc., (SEPR) announced that it has signed an agreement with MedPointe, Inc., for the copromotion of Astelin (azelastine HCl), a nasal-spray antihistamine. Astelin is the only...

First monoclonal antibodies could aid study, diagnosis of human caliciviruses.
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Microbiologists at the Baylor College of Medicine have reported the first monoclonal antibodies for any Sapporo-like viruses. N. Kitamoto and coworkers published their study in Journal of Clinical...

Trinity announces Remune study results.(Trinity Medical Group USA Inc.)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Trinity Medical Group USA, Inc., (GU) publicly announced clinical results presented at a scientific conference on therapeutic and preventive HIV vaccines indicating that HIV-positive patients in...

New approach to replacing immune cells shrinks tumors in patients.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- A new approach to cancer treatment that replaces a patient's immune system with cancer-fighting cells can lead to tumor shrinkage, researchers report in the journal Science. The study demonstrates...

Survey shows public lacks knowledge of danger.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Although 1.4 million Americans, mostly women, have a form of lupus, public recognition and understanding of the autoimmune disease remains low, according to a recent survey conducted for the Lupus...

Green tea may fight allergies.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Allergy sufferers may want to add green tea to their sniffle-fighting arsenal. New evidence suggests that drinking the popular brew may provide some relief. Researchers in Japan identified a...

Pregnancy hormone estriol shows promise as treatment in first human trials.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- A hormone common in pregnant women shows promise as an easily administered treatment for people with early-stage multiple sclerosis (MS). A new study by University of California at Los Angeles...

Over 60% achieve ACR20 with Genmab's HuMax-IL15.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Genmab A/S announced positive results from its HuMax-IL15 multidose phase I/II clinical trial for the treatment of rheumatoid arthritis. In the trial, 61% of patients achieved an ACR20, with 39% of...

Kidney transplant patients from 40 years ago, long off drugs.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- In a radical departure from the standard way of treating transplant patients, doctors from the University of Pittsburgh's Thomas E. Starzl Transplantation Institute have gone back to the future, so to...

Airway obstruction linked to ozone exposure.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Recent study findings suggest a link between airway obstruction and ozone exposure. "Proliferating cell nuclear antigen (PCNA) is a component of multiprotein complexes that are expressed during...

European Commission grants approval for Aranesp, Neulasta.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Amgen (AMGN) announced that the European Commission (E.C.) has approved both darbepoetin alfa (Aranesp/Nespo) for the treatment of anemia in adult cancer patients with solid tumors (nonhematological...

High-dose cyclophosphamide safe, effective against refractory hemolytic anemia.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- In a small study, high-dose cyclophosphamide was safe and effective treatment against refractory autoimmune hemolytic anemia. The drug, "without stem cell rescue, has been used successfully to...

Putative silencer element in IL-5 gene is recognized by Bcl6.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "The Bcl6 gene is ubiquitously expressed in adult murine tissues and its product functions as a sequence-specific transcriptional repressor. Bcl6-deficient...

Cambridge reports loss of 21.5 million pounds sterling.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology Group plc (CATG) reported financial results for the 9 months ended June 30, 2002, and an update on business for the period since the Interim Report in May 2002. ...

Activator protein-1 role in acute lung injury studied.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "The role of activator protein-1 (AP-1) in inflammation is primarily unknown. AP-1 was evaluated in nuclear extracts from alveolar macrophages and whole...

Monocyte activation increases in chronic hepatitis C patients given therapy.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Scientists have determined blood cells on the frontlines of war against disease don't lose their abilities in patients infected with chronic hepatitis C. ...

Paratek awarded NIH grant to search for antimalarial tetracyclines.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Paratek Pharmaceuticals, Inc., announced that it received a phase I Small Business Innovative Research grant from the National Institute of Allergy and Infectious Diseases. The grant was awarded...

Dead tumor cells contribute to immunogenicity of vaccine.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Avax Technologies, Inc., (AVXT) announced the publication of a scientific paper on studies of its AC Vaccine technology for the treatment of cancer. The paper, by David Berd, Department of...

Study reveals novel mechanism for immunotherapeutic efficacy.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- According to a study from Canada, "The efficacy of glatiramer acetate in multiple sclerosis (MS) is thought to involve the production of Th2 regulatory lymphocytes that secrete anti-inflammatory...

Alkylating agents used in immunotherapy of serpiginous choroiditis.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Johns Hopkins University researchers report improved long-term prognoses in a small group of serpiginous choroiditis patients who were treated with alkylating agents. Their study involved nine...

New immune globulin IV treatment submitted for approval in key markets.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Bayer Biological Products (BP) (BAY) announced that it has submitted its next generation immune globulin intravenous (IGIV) product for regulatory approval in the United States, Canada, and Germany....

Apoptosis underlies immunopathogenic mechanisms in acute silicosis.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Researchers in Brazil have examined "immunopathogenic roles for apoptosis in acute murine silicosis." V.M. Borges and colleagues, University Federal Rio de Janeiro, examined mice in which...

Praxis Pharmaceuticals financing complete.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Praxis Pharmaceuticals, Inc., (PRXX) announced that Praxis USA's former subsidiary, Praxis Australia, Pty. of which Praxis USA is a large shareholder, has just completed $9.4 million financing. ...

Antibodies aid diagnosis while IgM rheumatoid factors predict severity.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Rheumatologists in Switzerland conducted a study "to examine the value of anticyclic citrullinated peptide (anti-CCP) antibodies, anti-keratin antibodies (AKA) and immunoglobulin M rheumatoid factors...

FDA clears new diagnostic test for lupus.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has cleared for market a new screening test for lupus developed by researchers at the Fred Hutchinson Cancer Research Center. The test is considered the first...

Histone peptide-induced nasal tolerance suppresses SLE in mouse model.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- According to a study from England, "Induced mucosal tolerance has been shown to be beneficial in preventing or treating a number of murine and human autoimmune disorders. However, this particular form...

Alloantigens' codominant expression may impact immune response.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Recent findings suggest that the polymorphic MHC class I-related chain A (MICA) gene is codominantly expressed and this may play a role in the body's immune response to allograft transplantation. ...

Interim data on ISA(TX)247 presented.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Randall Yatscoff, president and chief operating officer of Isotechnika presented interim results of an ongoing phase II clinical trial at the annual International Congress of the Transplantation...

Early cessation of patient enrollment for Deligoparin trial announced.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Incara Pharmaceuticals Corporation (INCR) announced that its subsidiary, Incara Development, Ltd., has ceased further enrollment of patients into the clinical trial of deligoparin for the treatment of...

Rare disorder provides new insight into fighting infection.(caspase-8 deficiencies)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- Through studying a genetic condition known to exist in only two individuals, scientists at the U.S. National Institute of Allergy and Infectious Diseases (NIAID) and their colleagues have uncovered new...

Cancer cells made to express CD154 prompt strong anticancer activity.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Tumor cells made to express CD154 can enhance anticancer activity via several avenues, researchers report. A growing interest in cancer vaccine technology...

Sleep disorders may indicate worsening of problems.(Brief Article)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- For children with mild-to-moderate asthma, waking up during the night could be a sign that their asthma is getting worse, according to a study in the Journal of Allergy and Clinical Immunology. ...

Disorder associated with wide range of diseases.(endometriosis)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- U.S. researchers report in the journal Human Reproduction that women with endometriosis are significantly more likely than other women to suffer from a number of additional distressing or disabling...

Autoimmune disorder more common in chronic hepatitis C than suspected.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The autoimmune illness immune thrombocytopenic purpura (ITP) has been linked to chronic hepatitis C by researchers at Scripps Research Institute in La Jolla,...

U.S.-Russian team announces breakthrough.(treating drug-resistant tuberculosis)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- U.S. and Russian researchers have announced a major development in their joint efforts to find a treatment for drug-resistant tuberculosis at the Interscience Conference on Antimicrobial Agents and...

L19 antibody reaction to tumor antigen depends on molecular format.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Biodistribution studies have demonstrated recombinant L19 antibody could be used for targeting tumor vessels. Scientists believe L19 could be manufactured...

Kosmos, Allergychoices to develop oral immunotherapy product line.(Brief Article)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- Kosmos Pharma and Allergychoices announced their entry into a coventure to develop a line of film-based oral immunotherapy products. These products are an alternative to current injection-based...

Regular use of inhaled steroids cuts hospital admissions by a third.(Brief Article)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- Regular use of inhaled steroids cuts hospital admissions for severe asthma by almost a third, reveals research in Thorax. Most previous research has looked at the short-term effects of inhalers to...

Immediate immunity offers specific defense against pathogenic agents.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- Some scientists are suggesting that specific antibody reagents should be kept on hand to provide immediate immunity in the event of bioterrorism. A. Casadevall, Yeshiva University's Albert Einstein...