Immunotherapy Weekly articles from November 2001

Immunotherapy Weekly archives from November 2001

Immunoglobulins From Resistant Sex Workers May Provide Protection.(against HIV infection)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - HIV specific immunoglobulin from persistently uninfected sex workers may aid in the development of an HIV vaccine effective against a wide range of viral...

Neonatal Bone Marrow Transplantation Safe, Effective.(for the treatment of severe combined immunodeficiency)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Bone marrow transplantation can be safely and effectively used to treat infants suffering from severe combined immunodeficiency, according to researchers in...

Joint Cartilage Mimics Structure And Function of Natural Tissue.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- University of California, San Diego (UCSD) bioengineers have fabricated cartilage tissue which for the first time mimics the multilayered structure and cellular functions of natural articular cartilage....

Hemoglobin Vesicles Have Little Impact On Phagocytes.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Japan say that hemoglobin vesicles do not have a persistent effect on phagocytic activity in mice, offering hope that they may be suitable for...

Researchers Find A Key To Immunological Development.(during fetal period)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Children are born with the ability to make antibodies, proteins that fight infection. However, they do not respond to immunization in the same way as adults and several aspects of the immune system are...

Gene Vectors Might Be Next Best Thing For Vaccine Studies.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writers - Millions of patients affected by autoimmune illness, cancer, infections, and other diseases could one day be helped by taking gene therapies designed to...

Sometimes The Cure Is As Bad As The Symptoms.(nasal allergy medication may affect school performance as much as untreated allergies)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Even though school performance is impacted by some nasal allergy medications, a survey of school nurses shows that 88% agree that untreated nasal allergy symptoms interfere with school performance. ...

ImmuneTech To Develop Allergy Assays Based On Luminex's LabMAP Technology.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- ImmuneTech Inc. and Luminex Corp. (LMNX) have entered into a strategic partnership permitting ImmuneTech to develop and commercialize a line of allergy tests based on Luminex's proprietary Multi-Analyte...

FDA Awards $1.4 Million Grant For Drug Candidate.(Neurochem Inc. receives grant for the development of Fibrillex)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Neurochem, Inc. (NRM) announced that it received a $1.4 million grant from the U.S. Food and Drug Administration (FDA) for a Phase II/III study of Fibrillex, which is currently underway. The...

New DNA-Based Vaccine Approach Protects Mice.(against anthrax)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Researchers at Ohio State University have shown that mice injected with fragments of DNA from anthrax bacteria can be immunized against the disease. In traditional vaccine approaches, researchers...

Professor Ada Kruisbeek To Lead Crucell's Antibody Research.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Crucell NV (CRXL) has appointed renowned immunologist Ada Kruisbeek as senior vice president, head of oncology and inflammatory Diseases. Prof. Kruisbeek will lead Crucell's antibody research. ...

Phase II Study Of Humanized Anti-IL-4 Antibody Initiated.(anti-interleukin 4 antibody to be studied for asthma therapy)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Protein Design Labs, Inc. (PDL) announced the start of a Phase II clinical trial to evaluate its humanized antibody to interleukin-4 (IL-4) in asthma. The randomized, double-blind,...

Treatment Now Widely Available After Four-Year Limited Access.(HP Acthar Gel (repository corticotropin injection) now available for the treatment of infantile spasm)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Questcor Pharmaceuticals, Inc. announced that it began shipping HP Acthar Gel (repository corticotropin injection) to wholesalers after a four-year period during which limited supplies were available....

FDA Fast Tracks Antigenics' Oncophage For Kidney Cancer.(cancer vaccine for renal cell carcinoma treatment)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration has designated Oncophage, a cancer vaccine candidate developed by Antigenics, Inc. (AGEN), a Fast Track Product for the treatment of renal cell carcinoma. In...

T Cells Can Halt Development Of Skin Cancer, Yale Researchers Find.(gamma-delta T cells)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- In a study published in Science, Yale researchers show that (gamma)-(delta) T cells, a special kind of white blood cell found in the skin, are critical in the defense against skin cancer development....

Genetically Engineered Vaccine Elicits Immune Response To Kill Tumor.(caused by human papillomavirus 16)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- A genetically engineered vaccine appears to direct the immune system to kill tumors caused by human papillomavirus 16 (HPV-16), report researchers from the University of Pennsylvania and Johns Hopkins...

Multikine Effective In HIV/HPV Infected Women.(immunotherapy reasearch)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- A presentation at the Annual Meeting of the International Society for Interferon and Cytokine Research in Cleveland, Ohio, by scientists from the Institute of Human Virology (IHV) and CEL-SCI suggests a...

Avanir Pharmaceuticals Discusses Potential Docosanol Collaborations.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Avanir Pharmaceuticals (AVN), a diversified biopharmaceutical company engaged in research, development, commercialization, licensing, and sales of innovative drug products and antibody generation...

Researchers Prevent Disease In Mice By Blocking Leukocytes.(macrophage migration inhibitory factor for the prevention of intestinal ulcers in inflammatory bowel diseases)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- The intestinal ulcers of inflammatory bowel diseases, such as colitis, are often the result of collateral damage and if unchecked could eventually lead to colon cancer. In the November 2001 issue of...

Immune-Regulating Hormone Enters Clinical Trials.(Hollis-Eden Pharmaceuticals Inc. begins Phase II test of HE2000 for the treatment of hepatitis B)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc. announced that it has received approval to initiate a Phase II clinical trial in hepatitis B (HBV) infected patients with its investigational drug, HE2000, at Mt....

Oxagen Licenses Gene Polymorphism Patients From Isis Innovation.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Oxagen Limited in Abingdon, U.K., has acquired exclusive rights to a series of patents from Isis Innovation, the technology transfer arm of Oxford University. The patents cover gene polymorphisms...

Researchers Explain Gender Role In Susceptibility To Endocrine Disorders.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Thyroid autoimmune disorders such as Graves disease or Hashimoto thyroiditis and other autoimmune diseases have a strong, yet unexplained female preponderance. At the same time, some human lymphocyte...

Estrogen Protection May Explain Differences In Response Between Sexes.(estrogen may protect against Vibrio vulnificus infection associated endotoxic shock)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Estrogen may play a role in protecting against endotoxic shock associated with Vibrio vulnificus infection, a finding that may help explain the vast difference between the infection in men and women....

Cyclacel's CDK Inhibitor Candidate Meets Safety Objectives.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Cyclacel Limited, a United Kingdom-based cancer therapeutics company, has announced that CYC202, its lead CDK-inhibitor drug candidate, has completed Phase Ia evaluation in humans and is entering...

Phase II Trial Results Of Therapeutic Vaccine Are Encouraging.(Xenova Group PLC announces results of genital herpes vaccine)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Xenova Group plc (XNVA), had announced results from the Phase II clinical efficacy trial conducted in collaboration with its partner, GlaxoSmithKline (GSK), with TA-HSV, a therapeutic vaccine designed...

Early Cytotoxic T-Cell Responses May Be Key To Development.(of HIV vaccine)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Vaccines for HIV should harness the powerful cytotoxic T-lymphocyte (CTL) responses to the virus seen in the acute stages of infection, researchers in Wisconsin...

Foundation Urges Emergency Monitoring, Distribution For Clotting Medicine.(National Hemophilia Foundation)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- At a national workshop attended by the National Hemophilia Foundation (NHF), discussions on the current factor shortage identified the need for an emergency distribution system that would monitor the...

Revotar Biopharmaceuticals AG Licenses New Research Target.(therapy for rheumatoid arthritis)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Revotar Biopharmaceuticals AG, a majority-owned subsidiary of Texas Biotechnology Corp. (TXBI), has entered into a licensing agreement with the Fraunhofer Institute in Stuttgart, Germany, for macrophage...

Dynavax Defends Its Immunostimulatory Intellectual Property.(Dynavax Technologies initiates interference proceedings of dispute with Coley Pharmaceutical Group)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Dynavax Technologies has met with officials at the United States Patent and Trademark Office (USPTO) to initiate interference proceedings to resolve first-to-invent disputes with recently issued patents...

Celgene Receives Orphan Drug Designation For Revimid.(as a treatment for multiple myeloma)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Celgene Corp.'s Revimid, the company's lead immunomodulatory drug (IMiD), has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for multiple myeloma. Orphan drug...

Interferon Beta-1b Treatment Superior To Interferon Beta-1a.(for the treatment of multiple sclerosis)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Results from the Independent Comparison of Interferon (INCOMIN) trial released at the Italian Neurological Society meeting held September 30--October 3, 2001 in Rimini, Italy, revealed clinically...

T-Cell Surface Membranes Involved In Immune Response To Tuberculosis.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The immune response to tuberculosis infection is partly mediated by T-cell surface membrane stimulation, researchers in England report. "Mycobacterium...

Duke Researchers Uncover Clue To Kidney Damage After Heart Surgery.(gastrointestinal bacteria toxins released into bloodstream during surgery may be the cause of kidney damage)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Duke University Medical Center researchers have uncovered an intriguing clue why one of every 12 patients undergoing coronary artery bypass surgery suffers serious kidney impairment, and they believe...

Health Tips For Kids Coping With Asthma And Allergies.
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- For millions of children with asthma and allergies, fall can mean that uncomfortable symptoms like wheezing and sneezing may interfere with their daily lives at school and play. Asthma, one of the most...

Successful Treatment Opens Door For Treatment Of Other Autoimmune Diseases.(treatment of severe aplastic anemia with (cyclosphosphamide) Cytoxin)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- A newly proven cure for severe aplastic anemia, a fatal bone marrow failure disorder, has broad implications for a similar cure for the entire array of 80 autoimmune diseases (i.e., lupus erythematosus,...

Older, Less-Expensive Drugs Should Be First-Line Therapy.(for acute uncomplicated sinusitis)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Patients who receive newer, more expensive antibiotics for acute uncomplicated sinusitis have about the same rate of successful treatment as those treated with older, less expensive antibiotics, but the...

AAAAI, EPA Mount Effort To Raise Awareness To Dangers Of Secondhand Smoke.(American Academy of Allergy, Asthma and Immunology and the Environmental Protection Agency promote the Smoke Free Home Pledge Campaign)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Up to 40% of children in the United States live in homes where at least one adult smokes. Being exposed to this secondhand smoke increases a child's risk for developing asthma or worsening existing...

Alemtuzumab Successful In Clinical Trial.(for the treatment of T-cell prolymphocytic leukemia)
November 7, 2001... 2001 NOV 7 - (NewsRx.com & NewsRx.net) -- Schering AG, Germany (SHR), announced that Campath (alemtuzumab), a humanized monoclonal antibody, was successfully tested in a clinical trial for the treatment of T-PLL (T-cell prolymphocytic...

Chill Syndrome, Fever Disorder Caused By One Protein.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Scientists have identified the genetic basis of two rare disorders whose symptoms are apparently all caused by an altered immune system protein. As reported by Hal M. Hoffman, MD, and colleagues in...

Busulfan, Neuraminidase Treatment Improves Tolerance Induction.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Japan have developed a system using specially treated bone marrow cells (BMCs) to enhance tolerance to transplanted organs. "The portal...

Gag-Specific Helper T Cells Aid In Viral Control.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Helper T cells that recognize the HIV Gag protein play a significant role in the body's immune response to the virus, according to researchers in the United...

Intermediate Viral Structures May Be Target.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Viral structures formed during HIV coreceptor interactions can be targeted by potential HIV vaccines, researchers in the United States report. "Human...

Immune System Response Performs Poorly In Elderly.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Aging brings with it a decline in immune function leading to increased vulnerability to disease and delay in recovery after illness, both of which should be of concern as the American population ages...

Boosting Interferon-Gamma Could Clear Legionella Infections Faster.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Patients infected with Legionella pneumophila, might clear the infection faster if given intrapulmonary treatments of interferon (IFN)-gamma gene therapy. ...

Stress May Increase The Chances That Skin Wound Will Become Infected.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Stress may increase the chances that a skin wound will become infected, new research suggests. Researchers found that wounds on mice that were psychologically stressed were more than three times...

Laundry Detergent Effectively Removes Cat Dander And Dust Mites.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- If you have allergies or asthma triggered by pet dander or dust mites, your physician or allergist has probably recommended that you wash your bedding in very hot water every week to reduce your...

American Academy of Allergy, Asthma & Immunology: Red Eye Relief.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- The arrival of fall brings crisp air and an explosion of colors. People enjoy looking at the yellow leaves and orange pumpkins, but unfortunately some will see them through red eyes. About 22 million...

Reducing Exposure To Allergens Reduces Allergic Reactions.(Brief Article)(Statistical Data Included)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Twenty-eight percent of callers to a food allergy awareness organization reported experiencing allergic reactions to safe foods that were later found to contain unlabeled food allergens. Clear and...

Tips For Reducing Indoor Mold And Allergens.(Brief Article)(Statistical Data Included)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- In support of the U.S. Environmental Protection Agency's Children's Health Month, the Carpet and Rug Institute offers tips for parents, teachers, and child care providers for reducing common allergens...

Genes Play A Greater Role In This Disease Than Environment.(Brief Article)(Statistical Data Included)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Genes are likely to have a much bigger role than environmental factors in asthma, suggests research on twins in the Archives of Disease in Childhood. The United Kingdom, Australia and New Zealand...

Yale-Griffin Prevention Research Center To Study Complementary Care Of Asthma.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- The Yale-Griffin Prevention Research Center, part of the Yale School of Medicine, will soon begin work on a study of complementary care for mild to moderate asthma. Funded by the U.S. Centers for...

Avant Licenses Vaccine Technology to U.S. Department of Defense Contractor.(Avant Immunotherapeutics Inc. )(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Avant Immunotherapeutics Inc. (AVAN) has signed a license agreement with DynPort Vaccine Company LLC ("DVC") for exclusive rights to use certain components of Avant's vaccine technology. Financial...

Bio-Terrorism.Info Database and Weekly Report Launch Powered by NewsRx Artificial Intelligence Technology.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- NewsRx has leveraged its technology platform to create Bio-Terrorism.Info, a new database and weekly report. NewsRx is the leading provider of life science databases and daily and weekly health news....

Biomira Plans Interim Analysis Of Theratope Vaccine Data.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Merck KGaA and Biomira Inc. (BIOM) have announced that, following communications with the U.S. Food and Drug Administration (FDA), the companies will conduct a single interim analysis of data from...

Lymphoma Patients Sought For Customized Therapy Trial.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Patients with low-grade B-cell non-Hodgkin lymphoma who have received no prior therapy are being recruited by 22 of the top cancer research sites across the United States and Canada. These sites are...

Colorectal Cancer Patients Participate In Clinical Trial.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- An investigational vaccine for the treatment of colorectal cancer, one of the most common and deadly forms of cancer, has been cleared by the U.S. Food and Drug Administration (FDA) for clinical trial....

Therapy with Infliximab Prolongs Remission In Bowel Disease.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Maintenance dosing with the monoclonal antibody infliximab can prolong remission of the signs and symptoms of Crohn disease (CD), according to a study presented at the 66th Annual Scientific Meeting of...

New Gene Related To Inflammation Discovered.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Scientists at Exelixis, Inc. and the IMCB in Strasbourg, France, have identified and characterized a gene involved in mediating the innate immune response, a discovery that could have significant...

Researchers Identify Genetic Changes In Bacterial Biofilms.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Bacteria can exist in a free-floating (planktonic) form or as a biofilm where the cells form organized communities encased in a self-produced slime. One important difference between these two...

Irritable Bowel Syndrome Exacts Significant Toll On Society.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Two new studies on irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder, detail the high economic and social costs of the condition in the United States. The findings...

Companies Seek Patent Protection For Virus Analysis Technology.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Vigen Inc., a Wisconsin-based company that specializes in commercialization of antiviral technologies, and Commonwealth Biotechnologies Inc. (CBI), a contract research organization, have filed for...

Study Finds Colesevelam Effective in Reducing LDL Cholesterol.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Colesevelam hydrochloride appears to be an effective lipid-lowering agent that significantly reduces low-density lipoprotein (LDL) cholesterol levels, according to a study published in the October...

Cylex Inc. Signs Agreement With Dynal Biotech For Dynabeads Technology.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Cylex Inc., a privately held company, has entered into an agreement with Dynal Biotech ASA of Oslo, Norway for Dynal Biotech to supply Dynabeads to Cylex for use in conjunction with Cylex's patented In...

Hormonal Changes Can Alter Immune Response.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- It is generally recognized among immunologists that males of all species have lower immunity than females. Men are more susceptible to a variety of infections, such as dysentery, gonorrhea, and...

Flu Shots Important For People With Asthma.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Influenza can exacerbate asthma in children and adults, and now is the time for the nation's 17 million people with asthma to protect themselves with flu shots. The American Academy of Allergy,...

Sluggish Heart Responses May Tie Depression To Heart Attack Deaths.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Depression in heart attack patients may affect much more than their mental health. It may also affect the wiring of their heart, increasing the likelihood of death, according to research published in...

Radioimmunotherapy Improves Clinical Responses In Chemotherapy Refractory Disease.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- An investigational radioimmunotherapy, Bexxar (tositumomab and iodine I 131 tositumomab), demonstrates more durable complete or partial clinical responses in patients with low-grade and transformed...

Overexpression Of CREB Protein Plays Pivotal Role In Disease Development.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Researchers at Children's Research Institute, located on the campus of Columbus (Ohio) Children's Hospital, designed the first-ever transgenic model (genetically modified) to show how the CREB protein...

Caffeine Intake Increases Rate Of Bone Loss In Elderly Women.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Researchers have found that some women who consumer high amounts of caffeine are at greater risk for bone loss. Nutrition, lifestyle, and genetics may all contribute to the decrease in bone...

Study: Actonel Reduces Vertebral Fracture Risk 70% In Patients On Steroids.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Vertebral fracture risk in men and women who take oral glucocorticoid treatment (>7.5 mg/day prednisone or equivalent) for chronic diseases is significantly reduced with Actonel (risedronate sodium...

Oregovomab Produced Favorable Clinical Trial Results.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- AltaRex Corp. (ALXFF) announced favorable early results from a concurrent OvaRex/second-line chemotherapy clinical trial in relapsed ovarian cancer where prognosis is extraordinarily poor, and where...

Ulcer Patients May Need Warning Against Use Of NSAIDs.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- A study of more than 4000 Medicare patients with peptic ulcers suggests many are not being warned against using pain relievers such as aspirin and ibuprofen, which can cause the ailment or make it...

Drug May Prevent Wasting Often Seen In Victims Of Burns And Auto Wrecks.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- A widely used blood pressure drug shows strong potential for slowing the metabolic overdrive that makes patients waste away after severe burns and other major injuries, researchers say. The...

Biomira Initiates Phase II Pilot Study Of BLP25 Vaccine.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Biomira Inc. (BIOM, BRA) has initiated of a Phase II clinical trial evaluating BLP25 vaccine in patients with prostate cancer. The study is designed to test active specific immunotherapy with...

Botanical-Based Therapy Has Effect Similar To Low-Dose Chemo.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- The combination botanical therapy called PC-SPES has been found to be effective at affecting measures that indicate prostate cancer activity, according to Sophie Chen, PhD, a leading expert in drug...

Isotechnika Begins Psoriasis Trials.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Isotechnika Inc., has announced that Canadian trials have begun using its immunosuppressive drug ISATX247 with patients suffering from psoriasis. These Phase II trials were approved by Health Canada in...

HuMax-IL15 Potent Against Inflammation.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Genmab A/S has announced that HuMax-IL15, a human monoclonal antibody targeting the cytokine interleukin (IL)-15, demonstrated potent activity in arresting inflammation in preclinical studies. ...

Novel Intravenous Protectant To Undergo Phase I Trial.(Brief Article)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- AtheroGenics, Inc. announced that it has begun a Phase I clinical trial with AGIX-4207 I.V. as an intravenous treatment for people with rheumatoid arthritis. The Phase I trial is designed to assess...

Dendreon Acquires Rights To Telomerase Antigen From Geron.
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Dendreon Corp. (DNDN) has licensed rights from Geron Corp. (GERN) to use human telomerase (hTERT) as an antigen in Dendreon's therapeutic cancer vaccines. Associated with the "immortality" of...

Sunesis And Chiesi Enter Drug Discovery Agreement.(Sunesis Pharmaceuticals Inc.; Chiesi Farmaceutici S.p.A.)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Sunesis Pharmaceuticals Inc. and Chiesi Farmaceutici S.p.A have entered into a research collaboration to discover and develop small molecules that inhibit a well-validated protein-protein target...

Isto Receives Grant To Develop Neocartilage Osteochondral Allograft.(Isto Technologies Inc.)
November 14, 2001... 2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Isto Technologies Inc. has received a three-year Advanced Technology Program (ATP) award of $2 million from the National Institutes of Standards and Technology (NIST). The award will help fund the...

New Technique Helps Immune System Detect, Fight Cancer.(Brief Article)
November 21, 2001... 2001 NOV 21 - (NewsRx.com & NewsRx.net) -- A new therapeutic technique helps the immune system identify and attack abnormal cells, according to Howard M. Grey, MD, a leading expert in immunotherapy for cancer. "It was once thought that...

Sharp Drop In Stress Hormones May Set Stage For Arthritis, MS.(Brief Article)
November 21, 2001... 2001 NOV 21 - (NewsRx.com & NewsRx.net) -- A sharp drop in stress hormones after giving birth to a child may predispose some women to develop certain conditions in which the immune system attacks the body's own tissues, according to researchers...

Cellular Factors Expand Grass Allergen Vaccine Effectiveness.(Brief Article)
November 21, 2001... 2001 NOV 21 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Vectors encoded with the genes for two cytokines will increase allergen immunotherapy effectiveness. The two cytokines, interferon (IFN)-gamma and...