Immunotherapy Weekly articles from July 2004

Immunotherapy Weekly archives from July 2004

Dendritic cell treatment can reverse allergic Th2 responses in vitro.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Treatment of dendritic cells (DCs) can reverse allergic T helper 2 (Th2) responses in vitro. DCs are "the most potent APCs with the capacity to induce, modulate, or shut down immune function,"...

Anti-CD137 monoclonal antibody humanized.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A novel anti-CD137 mAb has been humanized. "Anti-4-1BB (CD137) monoclonal antibody (mAb) has been reported to suppress immune responses and to have the potential for use as a therapeutic agent to...

Cloned transgenic animals produce high levels of antitumor bispecific antibody.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Cloned transgenic animals can produce high levels of a bispecific antitumor antibody "Complex recombinant antibody fragments for modulation of immune function such as tumor cell destruction have...

Wolfberry-derived complex shows promise as cancer immunotherapy.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A compound derived from Chinese wolfberry has potent immunotherapeutic effects in a murine cancer model. In a recent study from China, the "modulation of a polysaccharide-protein complex from...

Retinoic acid receptor-alpha-selective agonist prevents allograft rejection.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A novel RAR-alpha agonist prevents allograft rejection in a murine model of heart transplantation. "To investigate the involvement of retinoic acid receptor (RAR)-alpha in allograft rejection,"...

Molecular analysis of adenovirus isolates from young adults reported.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Researchers have performed a molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults. "Infections of adenovirus type 4 (Ad4) and Ad7 were discovered among previously...

Severe infections plague acute alcoholic hepatitis patients given infliximab.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Severe infections plague acute alcoholic hepatitis patients given infliximab. According to published research from France, "tumor necrosis factor-alpha (TNF-alpha) may contribute to the progression...

S. mansoni modulates immediate hypersensitivity skin response to mite allergens.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Schistosoma mansoni infection could modulate the immediate hypersensitivity skin response to mite allergens. "Helminthic infections and allergic diseases are highly prevalent in many parts of the...

Creola bodies in wheezing infants predict asthma development.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Creola bodies in wheezing infants predict asthma development. "Creola bodies (CrBs) have been shown to be present specifically in the sputum of adults with asthma, and are clinically useful in the...

Toxic exposure to molds and mycotoxins yield abnormal neurological functions.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Toxic exposure to molds and mycotoxins yield abnormal neurological functions. One hundred "patients who had been exposed to toxic molds in their homes" were studied. "The predominant molds...

New tests developed for nut allergens.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Scientists in Florida have developed sensitive new tests to detect potentially fatal nut traces in food. Their study, published in the Journal of the Science of Food and Agriculture, originally set...

Pemirolast is a potent reliever of paclitaxel-induced allergic reactions.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Pemirolast is a potent reliever of paclitaxel-induced allergic reactions. According to recent research published in the journal Neuropharmacology, "the effects of anti-allergic agents on the...

DDR1/DDR2 potential role in obstructive diseases of blood vessels and lungs.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Discoidin domain receptors 1 and 2 have potential roles in obstructive diseases of the blood vessels and lungs. According to a study from the United States, "Obstructive diseases of blood vessels...

Oxidized LDL enhances adhesion molecule expression in C. pneumoniae-infection.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Oxidized LDL enhances adhesion molecule expression in Chlamydophilia pneumoniae-infection "Chlamydophila pneumoniae is a common respiratory pathogen that has been shown to be associated with...

''Collateral damage'' linked to cephalosporin or quinolone antibiotic therapy.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- ''Collateral damage'' is linked to cephalosporin or quinolone antibiotic therapy. "Collateral damage'' is a term used to refer to ecological adverse effects of antibiotic therapy; namely, the...

Antiviral proteins from C. album L leaves inhibit virus infections.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Antiviral proteins from Chenopodium album L leaves inhibit virus infections. According to published research from India, "Antiviral proteins (AVPs) named CAP-I and CAP-II purified from the leaves of...

MediciNova acquires phase II anxiety compound.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- MediciNova, Inc., a privately held specialty pharmaceutical company, announced the acquisition of a potential treatment for anxiety disorders from Mitsubishi Pharma Corp. of Japan. The compound,...

Myocytes of chorionic vessels from placentas with MAVN exhibit apoptotic markers.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Myocytes of chorionic vessels from placentas with meconium-associated vascular necrosis exhibit apoptotic markers. According to published research from the United States, "Meconium-associated...

Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401).
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Collagen-induced arthritis is mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401). According to recent research published in the American Journal of the Medical Sciences, "Although associations between...

Long-term relief from arthritis could evolve from B-cell targeted treatments.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Long-term relief for arthritis sufferers could be one step closer, thanks to a study of B-cell-targeted therapy. The study from University College London (UCL) reveals a major but hitherto poorly...

Study finds cancer drug appears highly effective against arthritis.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- For the first time, a drug has relieved rheumatoid arthritis by knocking out a certain type of immune cell, an approach that could open the way for precisely targeted, "smart" treatments for the joint...

Prevalence, exposure to mouse allergen may contribute to asthma.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Mouse allergen has a widespread presence in U.S. homes and may contribute to the development of asthma, according to a study featured in the June 2004 Journal of Allergy and Clinical Immunology (JACI)....

Juvenile arthritis may be part of 18q- syndrome.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Juvenile rheumatoid arthritis may be part of chromosome 18q- syndrome. "Previously, four children with deletion of the long arm of chromosome 18 and chronic arthritis were reported," according to...

Oral efficacy confirmed for autoimmune disease therapeutics.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- ProMetic Life Sciences Inc. (PLI) announced that its Therapeutic Unit has confirmed the oral efficacy of two of its new compounds for the treatment of chronic inflammatory conditions. "In less than...

T cell expansion during immune insufficiency generates autoimmunity.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. "During illness and stress, the immune system can suffer a considerable loss of T cells (lymphopenia). The...

UVB-irradiated dendritic cells fail to tolerize murine CD8+ T cells.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- UVB-irradiated dendritic cells fail to tolerize murine CD8+ naive or effector T cells. "UVB radiation has been shown to induce T cell tolerance most likely via modulation of the function of...

B. henselae genotype I strains may be more pathogenic than type II strains.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Bartonella henselae genotype I strains may be more pathogenic than genotype II strains. According to recent research published in the Journal of Clinical Microbiology, "Bartonella henselae is the...

Bacteria LPS induce IL-6-dependent plasmacytoma proliferation.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Bacterial lipopolysaccharides induce IL-6-dependent plasmacytoma proliferation by MAPK pathway activation. According to published research from Bulgaria, "Mouse plasmacytomas are appropriate models...

Lipoprotein NlpI involved in virulence of adherent invasive E. coli strain LF82.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Lipoprotein NlpI is involved in the virulence of adherent invasive E. coli strain LF82. According to recent research published in the journal Infection and Immunity, "Escherichia coli strain LF82...

Patients with chronic ulcers and erosions should be screened for MRSA.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Patients with chronic ulcers and erosions should be screened for MRSA. According to a study from Germany, "The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) was prospectively...

Fault tree analysis used to assess bioterrorist risks to the U.S. food supply.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Fault tree analysis is used to assess bioterrorist risks to the U.S. food supply. According to a study from the United States, "Concerns about terrorist use of biological agents have increased at...

Factors affecting efficiency of immunoporation cell transfection identified.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Factors affecting the efficiency of cell transfection by immunoporation have been identified. "Immunoporation is a recently discovered method that is able to transfect various human cell lines...

Positive data presented on IRHs and bone-marrow protection.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc., (HEPH) announced results from a presentation given at the American Society of Clinical Oncology (ASCO) meeting demonstrating positive results with investigational...

ER- breast cancer cell ERa re-expression recreate hormone-responsive phenotype.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Estrogen receptor negative breast cancer cell ERalpha re-expression recreate a hormone-responsive phenotype. "Estrogen receptor (ER)-negative breast carcinomas are often difficult to treat with...

Encouraging results for Oncotype DX assay in predicting chemotherapy response.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Genomic Health, Inc., and Istituto Nazionale Tumori, a cancer-research institute located in Milan, Italy, announced preliminary results of a clinical trial in which the patterns of expression of a...

New prognostic markers for survival of breast cancer identified.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- New prognostic markers for survival of breast cancer have been identified. According to a study from England, "The normal duct-lobular system of the breast is lined by two epithelial cell types,...

Several parallel and stepwise progression pathways towards breast cancer.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- There are several parallel and stepwise progression pathways towards breast cancer. "Distinct parallel cytogenetic pathways in breast carcinogenesis could be identified in recent years....

Islet Sheet Medical changes name; Kurt E. Amundson becomes CFO.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Cerco Medical announced that it has changed its name from Islet Sheet Medical, LLC, to Cerco Medical. The company also announced that Kurt E. Amundson has joined the company as vice president and...

Interleukin-12 arrests canine hemangiosarcoma growth in murine xenografts.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Interleukin-12 arrests canine hemangiosarcoma growth in canine xenografts. "We established a canine hemangiosarcoma cell line derived from malignant endothelial cells comprising a spontaneous tumor...

FDA grants fast track designation for MedPulser Electroporation Therapy System.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB) has been granted a fast track designation by the U.S. Food and Drug Administration for its MedPulser Electroporation System clinical development program for patients...

Key Herceptin data presented at ASCO meeting.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., (DNA) announced updated results from a phase III study evaluating Herceptin (Trastuzumab) in combination with paclitaxel and carboplatin, as well as a retrospective analysis of the...

Trial results reported in HGS-ETR1 in patients with advanced cancers.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced that the results of ongoing phase I clinical trials demonstrate the safety and tolerability of HGS-ETR1 (agonistic human monoclonal antibody to TRAIL...

Folate-mediated targeting of T cells to tumors reviewed.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Scientists review folate-mediated targeting of T cells to tumors in a recent issue of Advanced Drug Delivery Reviews. According to recent research from the United States, "Recently various...

Immunological therapies in lymphoproliferative disorders reviewed.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A scientist reviews the accomplishments and perspectives of immunological interventions in lymphoproliferative disorders in a recent issue of the Journal of Experimental and Clinical Cancer Research....

T cells primed by DCs pulsed with hepatoma acid-eluted substances.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Natural killer T cells can be primed in vivo by dendritic cells (DCs) pulsed with hepatoma-derived acid-eluted substances. "Many murine tumor cells express not only individual haplotype-matched...

Toll-like receptor signals needed to reverse regulatory CD8 tolerance.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. According to a study from the United States, "One chief barrier to cancer immunotherapy...

Tumor suppressor candidate protein in PTEN turnover identified.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Scientists have identified a tumor suppressor candidate protein in phosphatase and tensin homologue deleted on chromosome 10 (PTEN) turnover. According to published research from Japan, "The turnout...

Companies ink agreement regarding universal high-titer mammalian cell line hosts.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Morphotek, Inc., announced that it has signed a collaborative research agreement with Tanox, Inc., (TNOX) of Houston, Texas, for the use of Morphotek's proprietary SIP Technology to develop universal...

ICOS inks exclusive collaboration for antibody therapeutics.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- ICOS Corp. (ICOS) and Raven biotechnologies, inc., announced that they have entered into an agreement that provides ICOS with an exclusive option to license five of Raven's monoclonal antibody...

Data: Panitumumab has single-agent antitumor activity in colorectal cancer.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Amgen, Inc., (AMGN), and Abgenix (ABGX), an antibody-development company, announced interim data from an ongoing phase II study demonstrating that panitumumab (formerly ABX-EGF), a fully human...

CTL precursor-oriented peptide vaccine promising for colorectal cancer.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Results from a phase I trial indicate some benefit from cytotoxic T-lymphocyte (CTL) precursor-oriented peptide vaccines for colorectal carcinoma patients. According to recent research from Japan,...

Education program addresses diagnosis, management of acne in teens.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- The National Campaign to Control Acne (NCCA) announced the launch of its annual continuing medical education (CME) program to raise awareness of acne's incidence and prevalence among preadolescents and...

DNA "acrobatics" of immunoglobulin class switch reviewed.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- The DNA "acrobatics" performed during the immunoglobulin (Ig) class switch have been reviewed. "Small resting B lymphocytes all start out producing IgM Abs [antibodies]. Upon encountering Ag...

Allergens from M. sympodialis may play role in atopic eczema/dermatitis syndrome.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Allergens from the yeast Malassezia sympodialis may play a role in atopic eczema/dermatitis syndrome. According to recent research from Sweden, "Malassezia sympodialis is an opportunistic yeast...

KIR polymorphisms linked to psoriasis.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Several KIR polymorphisms have been linked to psoriatic disease. "To elucidate the association between killer cell immunoglobulin-like receptors (KIRs) and psoriasis vulgaris (PV)," dermatologists...

Dopexamine modulates cellular immune functions during systemic inflammation.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Dopexamine modulates cellular immune functions during systemic inflammation. "An immune-neuroendocrine interaction that is mediated via beta[subscript]2-adrenergic receptors has been demonstrated...

ADA initiates research program to prevent type 1 diabetes.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- The American Diabetes Association (ADA) announced at the ADA's 64th Scientific Sessions a collaboration with Entelos, Inc., to initiate a cutting-edge research program aimed at preventing type 1...

Companies sign distribution agreement for NMP22 Test Kit.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Matritech, Inc., (MZT), a developer of protein-based diagnostic products for the early detection of cancer, and Wampole Laboratories, LLC, a wholly owned subsidiary of Inverness Medical Innovations,...

Denaturing high-performance LC assay suitable for TNFRSF6 genotyping.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A novel liquid chromatography assay is suitable for use in TNFRSF6 genotyping. In a recent study from Norway, "[d]enaturing high-performance liquid chromatography (DHPLC) was evaluated as a tool for...

Immunomodulatory Achillea oils characterized.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A pair of immunomodulatory Achillea-derived essential oils have been characterized. In a recent study, "the oils of Achillea talagonica and A. millefolium, which grow widely in Iran," were...

Polyamine derivatives show immunosuppressive activities.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A series of polyamine-derived compounds have demonstrated immunosuppressive activities. In a study from Portugal, three "polyamine derivatives assigned as bis-naphthalimidopropyl putrescine...

Different levels of adherence determine specific antiretroviral resistance.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Different levels of adherence determine specific antiretroviral resistance. According to a study from the United States, "Public health debates about providing HIV antiretroviral therapy to...

Novel gene therapy approach suppresses autoimmune encephalomyelitis.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Scientists have developed a novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP. ...

Acetylcholine is an autocrine/paracrine hormone in lung bronchial epithelium.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Acetylcholine is an autocrine/paracrine hormone in lung bronchial epithelium. According to published research from the United States, "The role of acetylcholine (ACh) as a key neurotransmitter in...

CART peptide in anterior pituitary gland suppresses prolactin secretion.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Cocaine- and amphetamine-regulated transcript peptide in the anterior pituitary gland suppresses prolactin secretion. "Cocaine- and amphetamine-regulated transcript (CART) mRNA and CART peptide are...

Estrogen mediates sex difference in stress-induced prefrontal cortex dysfunction.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Estrogen mediates sex differences in stress-induced prefrontal cortex dysfunction. According to recent research from Yale University, "Many anxiety disorders, as well as major depressive disorder...

Leptin signaling targets thyrotropin-releasing hormone gene promoter.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Leptin signaling targets the thyrotropin-releasing hormone gene promoter. According to a study from the United States, "The regulation of TRH gene expression in the paraventricular nucleus of the...

Trypsin increases inflammatory response after intestinal ischemia-reperfusion.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Trypsin increases the inflammatory response following acute intestinal ischemia-reperfusion. "Ischemia-reperfusion of the intestine produces a set of inflammatory mediators, the origin of which has...

apoA-II regulates HDL stability and affects hepatic lipase association.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association. According to recent research published in the Journal of Lipid Research, "The effect of apolipoprotein A-II...

Cancer mortality rates in Europe are variable.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Cancer mortality rates in Europe are variable. "Mortality data, abstracted from the World Health Organization database, are presented in tabular form for 26 cancer sites or groups of sites, plus...

Biopharmaceutical company reports fourth quarter financial results.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Repligen Corporation (RGEN) reported results for the fourth quarter and fiscal year ended March 31, 2004. Total revenue for the fiscal year ended March 31, 2004, was $6,914,000 compared to total...

PELP1 expression modulated by E2-ER pathway and PELP1 is an ER target gene.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- PELP1 expression is modulated by the E2-ER pathway and PELP1 is an ER target gene. "Proline-, glutamic acid- and leucine-rich protein 1 (PELP1)/modulator of nongenomic activity of estrogen receptor...

Sphingomyelin synthase 1 plays a critical role in the growth of lymphoid cells.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Sphingomyelin synthase 1 plays a critical role in the growth of lymphoid cells. "Sphingomyelin (SM) synthase has been assumed to be involved in both cell death and survival by regulating...

HOX and HOX cofactor genes are expressed in the mammalian ovary.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- HOX and HOX cofactor genes are expressed in the mammalian ovary. According to published research from Italy, "Very little is known about the expression and function of the HOX and HOX-cofactors...

Somatic hypermutation limited by CRM1-dependent AID nuclear export.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Somatic hypermutation (SHM) is limited by CRM1-dependent nuclear export of activation-induced deaminase (AID). SHM and "class switch recombination (CSR) are initiated in activated B lymphocytes" by...

Alzheimer researcher receives grant to study dementia/HIV-related issues.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- William H. Frey II, PhD, director of the Alzheimer's Research Center at HealthPartners Research Foundation, was awarded a $200,000 grant to study the use of his intranasal drug delivery system towards...

Early diagnosis and treatment of primary HIV-1 infection may be critical.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Early diagnosis and treatment of primary HIV-1 infection may be critical. According to recent research published in the journal Clinical Infectious Diseases, "Emerging evidence suggests that early...

Fusion inhibitors effective in HIV patients able to maintain virological control.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Fusion inhibitors are effective in HIV patients that are able to maintain virological control. "The number of antiretroviral-experienced HIV patients with multiple resistances against the currently...

Low-dose iron supplementation does not increase HIV-1 load.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Low-dose iron supplementation does not increase HIV-1 load. According to published research from Denmark, "Observational data suggest that iron may increase HIV replication and the rate of...

Sleep deprivation protects against HIVgp120 and TNF-alpha deleterious effects.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Sleep deprivation protects against the HIVgp120 and TNF-alpha deleterious effects. According to recent research published in the journal Neuroscience Letters, "The human immunodeficiency virus (HIV)...

Kaposi sarcoma is a model for cancer immunotherapy.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Kaposi sarcoma is a model for cancer immunotherapy. For over a century physicians have "attempted to harness the potential therapeutic power of the immune system to treat patients with cancer. The...

Management strategy for anemia in HIV infection elucidated.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- A management strategy for anemia in HIV infection has been elucidated by consensus. According to a study from the United States, "Anemia in human immunodeficiency virus (HIV)-infected patients can...

HAART-PI but not HAART-NNRTI strongly inhibit SAP expression in the oral cavity.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Highly active anti-retroviral therapies with protease inhibitors but not non-nucleoside reverse-transcriptase inhibitors strongly inhibit SAP expression in the oral cavity. "Highly active...

HIV viral load rebounders have limited long-term naive CD4+ cell reconstitution.
July 7, 2004... 2004 JUL 7 - (NewsRx.com & NewsRx.net) -- HIV viral load rebound patients have limited long-term naive CD4+ cell reconstitution. According to a study from Greece, "Long-term (3.5 years) immune reconstitution in relation to viral load...