Immunotherapy Weekly articles from April 2003

Immunotherapy Weekly archives from April 2003

Medication protects patients with peanut allergies.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A new medication could help most people with peanut allergies avoid life-threatening allergic reactions. A research team led by Donald Leung, MD, PhD, of National Jewish Medical and Research...

Fish oil may reduce symptoms.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- New research from the University of Ulster offers hope to millions of lupus sufferers worldwide. Dr. Emeir Duffy, from the School of Biomedical Sciences, and Dr. Gary Meenagh, from Musgrave Park...

A new membrane associated adaptor molecule, LAB, is similar to LAT.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A new membrane associated adaptor molecule, LAB, is similar to LAT. According to a study from the United States, "The adaptor molecule, linker for activation of T cells (LAT), is essential in T cell...

Vaccination with plasmids of infectious bursal disease virus protective.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- DNA vaccination with plasmids containing various fragments of large segment genome of infectious bursal disease virus protected chickens against disease. "The present study was undertaken to...

B7-H1 autoantibodies react with antigen on T cells to induce apoptotic response.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- B7-H1 autoantibodies react with antigen on T cells to induce apoptotic response. According to a study from the United States, "A pathogenic hallmark of rheumatoid arthritis (RA) is persistent...

Dendritic cells play a key role in immune protection.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Dendritic cells play a key role in immune protection. According to recent research from Sweden, "Dendritic cells (DC) are an important link between the innate and adaptive immune response and are...

A feedback loop between tolerogenic dendritic and regulatory T cells is present.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A feedback loop between tolerogenic dendritic and regulatory T cells is present. According to recent research from Canada, "An active role of T regulatory cells (Treg) and tolerogenic dendritic...

Polarized epithelial cells sensitive to the pore-forming toxin aerolysin.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Polarized epithelial cells sensitive to the pore-forming toxin aerolysin. According to recent research from Switzerland, "Aerolysin is one of the major virulence factors produced by Aeromonas...

Ambient fine and coarse particle suppression of alveolar macrophage functions.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Ambient fine and coarse particle suppression of alveolar macrophage functions. According to recent research from The Netherlands, "Alveolar macrophages (AM) are part of the innate immunological...

Mastocytosis may be underlying cause of unexplained repeated anaphylaxis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Mastocytosis is the underlying cause in some patients suffering from repeated episodes of unexplained anaphylaxis, according to a study presented at the 60th anniversary meeting of the American Academy...

Patients with a PAF-AH deficiency at greater risk of fatal anaphylaxis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Patients with a deficiency in the enzyme platelet activating factor acetylhydrolase (PAF-AH) face a greater risk of fatal anaphylaxis, according to a study presented at the 60th anniversary meeting of...

New research on allergic disease in children presented.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Targeted cockroach extermination and intensive cleaning can lead to dramatic reductions in the levels of cockroach allergen present in the home, according to research presented at the 60th Anniversary...

Allergies contribute to significant economic implications in U.S. workplace.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Results from a new study presented at the American Academy of Allergy, Asthma and Immunology annual meeting show that allergic rhinitis costs employers millions of dollars annually. Specifically, a...

Chemokine receptors play a key role in inflammatory cell recruitment.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Chemokine receptors play a key role in inflammatory cell recruitment. According to a study from Italy, "Chemokine receptors play a key role in directing the migration of inflammatory cells into...

New research on the mechanisms of allergic disease released at AAAAI meeting.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The discovery of a new gene involved in asthma may provide a link between the development of asthma and obesity, researchers reported at the 60th anniversary meeting of the American Academy of Allergy,...

Pittsburgh allergic disease specialists identify molecular clue to asthma.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Children who suffer from asthma or allergic rhinitis have a diminished ability to stimulate dendritic cell interleukin-10 production (IL-10), which may contribute to the cause of their disease,...

Increased TGF-beta 1 is linked to advanced and/or longterm disease.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Increased TGF-beta 1 is linked to advanced and/or longterm disease. According to recent research from Poland, "Previous investigations have shown that TGF-beta 1 may protect neurons against...

Apolipoprotein E detection in CSF and serum yield the same results.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Apolipoprotein E detection in CSF and serum yield the same results. "We developed a simple method to detect apolipoprotein E (Apo E) polymorphism distribution in approximately 20 microL of...

Granzyme A cleaves the oxidative repair protein Ape1, enhancing cell death.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Granzyme A cleaves the oxidative repair protein Ape1, enhancing cell death. According to a study from the United States, "The cytolytic T lymphocyte protease, granzyme A (GzmA), initiates a caspase...

Dog exposure may prolong the onset of allergies and asthma.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Exposing a child to a dog, but not a cat, in the first year of life may prolong the development of allergies, researchers reported at the 60th anniversary meeting of the American Academy of Allergy,...

Environmental tobacco smoke linked to decreased lung function.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A significant link was shown between high levels of environmental tobacco smoke (ETS) exposure and decreased lung function in asthmatic children, according to a study presented at the American Academy...

Genetic variation may predispose African Americans to asthma.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A genetic variation may predispose African Americans to asthma, according to research presented at the 60th anniversary meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI). In...

Guide helps expectant mothers with asthma.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Allergy & Asthma Network Mothers of Asthmatics (AANMA) has developed an informative booklet to help expectant mothers face the challenges of pregnancy with asthma. "Breathing for Two: A Guide to...

High fat diets increase child's risks for respiratory problems.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Children with high fat diets could be at an increased risk for developing allergies and asthma, researchers reported at the 60th anniversary meeting of the American Academy of Allergy, Asthma and...

High serum leptin levels could help manage asthma exacerbations.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Serum leptin levels may play an important role in the management of asthma exacerbations, according to a study presented at the 60th anniversary meeting of the American Academy of Allergy, Asthma and...

New allergy/asthma treatment targets chemokines.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Inactivating a specific chemokine receptor in the body has been found to short circuit the inflammatory process, said researchers at the 60th anniversary meeting of the American Academy of Allergy,...

Researchers discover new asthma treatment target.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Recent studies have discovered an amino acid that may be involved in allergic disease. This pathway, not previously associated with asthma, may provide for a new pharmacotherapy treatment for...

Researchers explore caregiver management.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Asthma training and nurse consultant assistance is effective in improving asthma management in Head Start children, according to a study presented at the 60th anniversary meeting of the American Academy...

Researchers find specific gene variation in asthma, food allergy patients.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- People with asthma and food allergy have a specific variation of the gene CD14, which contributes to their allergic symptoms and reactivity. These findings were presented at the 60th anniversary...

TNF-alpha receptor is effective in chronic severe asthma.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Soluble tumor necrosis factor alpha (TNF-alpha) was found to be a useful supplement in the treatment of chronic severe asthma, researchers reported at the 60th anniversary meeting of the American...

CTLA-4 exon 1 polymorphism G was found in leukemic hemolytic anemia patients.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- CTLA-4 exon 1 polymorphism G was found in leukemic hemolytic anemia patients. "CTLA-4 is a CD28 homologue that plays an important role in negative regulation of T-cell responses. Its transient...

Blockers of sodium and calcium entry protect axons from nitric oxide.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Blockers of sodium and calcium entry protect axons from nitric oxide. According to a study from England, "Axonal degeneration can be an important cause of permanent disability in neurological...

Lipopolysaccharide-binding protein mediates LPS detoxification by chylomicrons.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Lipopolysaccharide-binding protein mediates LPS detoxification by chylomicrons. According to a study from the Netherlands, "Chylomicrons have been shown to protect against endotoxin-induced...

Pathophysiology has role in inflammation, infection and postinfectious sequelae.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Pathophysiology has role in inflammation, infection and postinfectious sequelae. According to recent research from Israel, "The literature dealing with the biochemical basis of bacteriolysis and its...

A serum test is more consistently reliable than the standard urine test.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A serum test is more consistently reliable than the standard urine test. "Bence Jones protein in urine (immunoglobulin free light-chains) is characteristic of light-chain multiple myeloma. We...

Activated T cells directly affect endothelial cells in inflammation.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Activated T cells directly affect endothelial cells in inflammation. According to a study from England, "Neuroinflammation is characterized by immune cell infiltration across the blood brain...

The alcaloid swainsonine has a significant stimulatory effect on bone marrow.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The alcaloid swainsonine has a significant stimulatory effect on bone marrow. "The immunomodulatory alkaloid swainsonine (8alphabeta-indolizidine-1alpha,2alpha,8beta-triol) has potential for...

Axillary lymph node drainage appears to be an important prognostic factor.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Axillary lymph node drainage appears to be an important prognostic factor. According to recent research from Hungary, "Axillary lymph node staging is an important prognostic factor in patients with...

Heterogeneity of mycolactones produced by clinical isolates of M. ulcerans.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Heterogeneity of mycolactones produced by clinical isolates of Mycobacterium ulcerans. According to a study from the United States, "Mycobacterium ulcerans is the causative agent of Buruli ulcer, a...

CYP isoforms appear to be high in liver and low in kidney after exposure.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- CYP isoforms appear to be high in liver and low in kidney after exposure. A study from Australia "investigated the possible link between nonworkplace cadmium (Cd) exposure, cytochrome P450...

Dendritic cell vaccine shows promise against cervical cancer.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Vaccination with dendritic cells pulsed with tumor lysate and matured with a novel synthetic clinically nontoxic, double-stranded RNA analogue poly [I]:poly[C[subscript]12U] (Ampligen) induced a strong...

NeM in type 2 inflammation has novel phenotype that can be partly replicated.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- NeM in type 2 inflammation has novel phenotype that can be partly replicated. According to recent research from Scotland, "Using a murine model of nematode infection, we have discovered macrophages...

Many CD83+ dendritic cells are found in myocardial inflammatory infiltrates.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Many CD83+ dendritic cells are found in myocardial inflammatory infiltrates. According to recent research from Germany, "Churg-Strauss syndrome (CSS) is characterized by a granulomatous vasculitis...

Rhodiola sachalinensis extract appears to protect from chemical liver injury.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Rhodiola sachalinensis extract appears to protect from chemical liver injury. "This study was carried out to investigate the protective effect of an aqueous extract from the root of Rhodiola...

Researchers review alternatives to surgical resection of liver metastases.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Researchers review alternatives to surgical resection of liver metastases. According to a study from the Peoples Republic of China, "The liver is the most common site of distant metastasis of...

Preparations can lead to kidney failure and the need for dialysis or transplant.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Herbal preparations can lead to kidney failure and the need for dialysis or transplant. "A new renal disease called Chinese herb nephropathy (CHN) has been reported to occur in women who have...

Endothelial cells induce T-cell chemokine CCL21 in autoimmune patients.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Endothelial cells induce T-cell chemokine CCL21 in autoimmune patients. "The signals that mediate T-cell infiltration during T-cell autoimmune diseases are poorly understood. The chemokine CCL21...

Proinflammatory cytokines can induce t-PA gene expression.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Proinflammatory cytokines can induce t-PA gene expression. "Plasminogen activator converts plasminogen to plasmin, and plasmin activates the latent matrix metalloproteinases. Tissue plasminogen...

Children with peanut allergy have a high anxiety levels.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Researchers found that children with peanut allergy have a higher anxiety level than children with diabetes, according to a study presented at the 60th anniversary meeting of the American Academy of...

Teens may be reluctant to take epinephrine, study says.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Teens are affected more by social consequences than by fear of food allergy reactions, causing a possible reluctance to use their medication, according to findings presented at the 60th anniversary...

Some physiological responses enhanced by connexin43, formation of gap junctions.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Some physiological responses enhanced by connexin43, formation of gap junctions. According to recent research from the United States, "In this work, the effects of bacterial LPS, TNF-alpha, and...

IL-10 gene expression upregulated in pathological mesangial cell proliferation.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- IL-10 gene expression upregulated in pathological mesangial cell proliferation. According to recent research from Australia, "Interleukin-10 (IL-10) has been recognized as a growth factor for rat...

Congenital erythropoietic porphyria can occur with cystic hygroma.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Congenital erythropoietic porphyria can occur with cystic hygroma. According to recent research from France, "Congenital erythropoietic porphyria (CEP) or Gunther disease is the rarest form of the...

Anti-glycoprotein 41 immunotoxins effective in mice.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Anti-glycoprotein 41 immunotoxins are effective against HIV infection in mice. "Immunotoxins (ITs) targeting the HIV envelope protein are among the most efficacious antiviral therapies when tested...

Nelfinavir inhibits lymphocyte P-glycoprotein activity.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The HIV protease inhibitor nelfinavir suppresses T-cell P-glycoprotein activity. "The efflux pump P-glycoprotein decreases drug penetration into cells and tissues," explained researchers in the...

Six-week, six-shot regimen works for more than one season.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Johns Hopkins researchers last year reported that an experimental treatment for severe ragweed allergy consisting of just six shots in 6 weeks dramatically reduced allergic symptoms such as runny nose,...

H. pylori-induced ERK1/2 activation guards against epithelial cell apoptosis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- H. pylori-induced ERK1/2 activation guards against epithelial cell apoptosis. According to a study from South Korea, "Helicobacter pylori induces activation of mitogen-activated protein kinases...

A novel apoptosis-inducing protein complex is related to pathogenesis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A novel apoptosis-inducing protein complex is related to pathogenesis. According to recent research from Japan, "Helicobacter pylori infection induces apoptosis in gastric epithelial cells. Here,...

A polymorphism in the human African interferon-gamma receptor limits disease.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A polymorphism in the human African interferon-gamma receptor limits disease. According to a study from Germany, "Helicobacter pylori is considered the most prevalent infectious agent among humans,...

Strong static magnetic field had no effect on normal lymphocytes.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A strong static magnetic field had no effect on normal lymphocytes. "We investigated whether static electromagnetic fields (EMFs) at a flux density of 4.75 T, generated by an NMR apparatus (NMRF),...

rFVIIa efficacious in treatment of major bleeding episodes.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- rFVIIa efficacious in treatment of major bleeding episodes. "Recombinant activated factor VII (rFVIIa, 'NovoSeven') is indicated for the treatment of spontaneous and surgical bleeding in patients...

Interleukin-18 binding protein therapy can neutralize cancer adhesiveness.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Interleukin-18 binding protein therapy can neutralize cancer adhesiveness Recent research from Spain "studied the role of endogenous IL-18 in hepatic metastasis by blocking this cytokine using the...

Display of HPV-16 E6-memory T-helper cells shows infection leads to immunity.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Display of HPV-16 E6-memory T-helper cells shows infection leads to immunity. According to recent research from the Netherlands, "Genital human papillomavirus (HPV) infection is common and the...

P38 MAP kinase is activated in ganglia and spinal cord postinflammation.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- P38 MAP kinase is activated in ganglia and spinal cord postinflammation. According to a study from South Korea, "The intrathecal administration of p38 MAP kinase (p38) inhibitor has been shown to...

Sympathetic nervous system affects the development of the immune system.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The sympathetic nervous system affects the development of the immune system. "It has been suggested that the sympathetic nervous system communicates with lymphocytes expressing cell surface...

Reductions in total body fat decrease humoral immunity.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A study in hamsters reveals that total body fat loss leads to impaired immunity, Dr. Gregory Demas and colleagues at Indiana University reported their findings in the Proceedings of the Royal...

Expressing ICOS defines CD4+ effector T cells with high inflammatory potential.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Expressing ICOS defines CD4+ effector T cells with high inflammatory potential. "The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model...

Discovery of a new subset of T cells involved in regulating intestinal immunity.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Our bodies are constantly under attack from infectious agents in the environment. The intestine is the largest body surface exposed to the outside world and must therefore be kept under constant...

Endogenous glucocorticoids attenuate Shiga toxin-2-induced toxicity.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Endogenous glucocorticoids ameliorate Shiga toxin-2-induced toxicity in mice. "The concept that during an immune challenge the release of glucocorticoids (GC) provides feedback inhibition on...

The bactericidal agent gentamicin enhances phagocytized bacterial killing.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The bactericidal agent gentamicin enhances phagocytized bacterial killing. "We employed gentamicin sensitive and resistant Escherichia coli in a macrophage phagocytosis assay that compared lambda...

Desensitization of T cells can inhibit cell signaling, adhesion and chemotaxis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Desensitization of T cells can inhibit cell signaling, adhesion and chemotaxis. According to a study from Israel, "T cells migrate into inflamed sites through the extracellular matrix (ECM) in...

Probiotics may be useful to prevent and treat inflammatory bowel disease.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Probiotics may be useful to prevent and treat inflammatory bowel disease. According to recent research from England, "The gut flora plays a fundamental role in maintaining normal intestinal...

Trimetazidine has effect on acetic acid-induced colitis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Trimetazidine has effect on acetic acid-induced colitis. According to recent research from Turkey, "Induction of colitis by acetic acid (AA) in the rat is widely used experimental model of...

IgA mediated defense may be differentially regulated by DeltaEC2.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- IgA mediated defense may be differentially regulated by DeltaEC2. "More than 10 splice variants of the Fc receptor for IgA (FcalphaR, CD89) have been identified in human myeloid cells. In this...

Spanish influenza mortality was higher in the Lap population in 1918-1919.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Spanish influenza mortality was higher in the Lap population in 1918-1919. "Previous studies into Spanish Influenza mortality have reported that indigenous populations were the prime victims. The...

Inflammation accelerates memory T cell migration to nonlymphoid tissues.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Inflammation accelerates memory T cell migration to nonlymphoid tissues. "Previous studies have shown that heterologous viral infections have a significant impact on preexisting memory T cell...

CD5 TCR gamma delta T cells play a role in mediated immune functions.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- CD5 TCR gamma delta T cells play a role in mediated immune functions. "Although CD4+ T cells form a major subset of TCRalphabeta T cells, only a small number of TCRgammadelta T cells express CD4....

Pyrrolidinedithiocarbamate inhibits NF-kappa B and thus IL-8 production.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Pyrrolidinedithiocarbamate inhibits NF-kappa B and thus IL-8 production. According to recent research from the United States, "During inflammatory bowel disease and intestinal ischemia, epithelial...

Chemokine receptor-mediated leukocyte vascular recognition analysis useful.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Chemokine receptor-mediated leukocyte vascular recognition analysis useful tool. According to a study from Italy, "Chemokines control selective targeting of circulating leukocytes to the...

Post-transplant monitoring by immune parameters may be preferable to drug level.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Post-transplant monitoring by immune parameters may be preferable to drug level. "The current standard of monitoring transplant patients by drug levels is not optimal because it does not take into...

Plasmid-mediated quinolone resistance discovered in clinical strain in 1994.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Plasmid-mediated quinolone resistance discovered in clinical strain in 1994. According to a study from the United States, "Quinolone resistance encoded by the qnr gene and mediated by plasmid pMG252...

The PPIase site of the Mip protein is essential for infection in host.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The PPIase site of the Mip protein is essential for infection in host. "We analyzed 8 monoclonal antibodies (mAbs) directed against the Mip (macrophage infectivity potentiator) protein, a virulence...

T(H)1, not T(H)2 responses depend on IFN-regulatory factor-4.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- T(H)1, not T(H)2 responses depend on IFN-regulatory factor-4. According to recent research from Japan, "IFN-regulatory factor (IRF)-4 is a member of the IRF family of transcription factors...

Tumor-derived soluble factors enhance activated T cell apoptosis.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Tumor derived soluble factors enhance activated T cell apoptosis. "T lymphocyte survival is critical for the development and maintenance of an effective host antitumor immune response; however, the...