Immunotherapy Weekly articles from April 2001

Immunotherapy Weekly archives from April 2001

Treatment With Killed Mycobacterium vaccae Improves Atopic Dermatitis.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Children with atopic dermatitis experienced significant improvement in symptoms after treatment with killed Mycobacterium vaccae. Because rates of...

Transplants Of Siblings' Cells Show Promise For Immune Disorder.(chronic granulomatous disease )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- U.S. National Institutes of Health (NIH) researchers in Bethesda, Maryland, have used a novel bone marrow transplantation procedure to successfully transfer stem cells from immunologically matched...

Venom Immunotherapy Improves Quality Of Life.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Venom immunotherapy results in an improvement in the health-related quality of life in individuals allergic to insect stings, researchers from The Netherlands and Canada said at the American Academy...

Institutions Seek Eligible Participants For Research Study On Peanut Allergy.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Seven U.S. medical research centers have come together to form the Centers for Peanut Allergy Awareness with the purpose of helping to increase knowledge of peanut allergy and how to handle its...

Leukemia Inhibitory Factor Can Prevent Vertical Transmission.(of HIV)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Illinois have shown that leukemia inhibitory factor (LIF), produced by the placenta, is a powerful inhibitor of HIV replication and may play a...

Interleukin-2 Can Hasten Immune Recovery In Patients Responding Slowly To ART.(antiretroviral therapy)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The cytokine interleukin-2 can help prevent infectious morbidity in HIV patients who do not respond quickly to antiretroviral therapy, researchers in France...

Benadryl Shown More Efficacious Than Claritin For Relief Of Nasal Symptoms.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- A leading over-the-counter (OTC) antihistamine, Benadryl (diphenhydramine), showed significant superior efficacy over the leading prescription medication loratadine (marketed as Claritin) in relief...

Vaccine Against Seasonal Rhinitis Is Safe.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Dynavax Technologies Corporation announced preliminary results March 20, 2001, at the 57th annual meeting of the American Academy of Allergy, Asthma, and Immunology from a Phase II clinical trial...

Anti-CD23 Monoclonal Antibody Demonstrates Safety, Efficacy.(asthma)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- IDEC Pharmaceuticals Corp. reports results from a single-dose, placebo-controlled, dose-escalating Phase I trial of its investigational agent IDEC-152, a primatized, anti-CD23 monoclonal antibody in...

Influenza Vaccine Protects Children From Respiratory Exacerbations.(asthma)
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Influenza vaccine can prevent worsening symptoms in young children with asthma, according to a large population-based study from the U.S. Centers for...

Low-Dose Fluticasone Propionate Aerosol More Effective Than Montelukast.(asthma )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- A study published in the March 2001 issue of the Journal of Allergy and Clinical Immunology showed that Flovent (fluticasone propionate) inhalation aerosol (44 mcg, two puffs twice daily) was...

Many Elderly Patients Not Receiving Proven-Effective Drug Treatments.(asthma )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Many elderly asthma patients are not receiving medications that have been proven to decrease the rate of hospitalizations and asthma-related deaths, according to a new Canadian study. Don D....

Study Demonstrates Trastuzumab With Chemotherapy Increases Survival.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., announced March 14, 2001, that women with one of the most aggressive forms of metastatic breast cancer experienced a significant survival benefit when treated initially with...

Naked DNA Vaccines Offer Better Anti-Tumor Potency Than Vaccinia Vaccines.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Two different vaccine vehicles carrying the same anti-tumor gene show significant differences in potency, according to a report published in Gene Therapy....

New Study To Investigate Chemokine Inhibitor's Role In Increasing White Blood Cells.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- AnorMED announced March 19, 2001, that it has initiated a new Phase I clinical trial in healthy volunteers to study the white blood cell count increasing effects of AMD-3100, an inhibitor of the...

Leukemia Survivors At Risk For Life-Threatening Infections.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Clinicians who care for long-term survivors of acute lymphoblastic leukemia (ALL) should test their humoral immune function to identify those at risk for severe or life threatening infections,...

Monoclonal Antibody Attacks Condition On A Molecular Level.(Psoriasis )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Psoriasis symptoms can be alleviated with Xanelim (efalizumab), one of a new class of targeted monoclonal antibody drugs, researchers said at the American Academy of Allergy, Asthma and Immunology...

New Treatment Appears To Demonstrate Lasting Benefit.(psoriasis )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Utah School of Medicine's Department of Dermatology have announced the results of a clinical trial in which alefacept (human LFA-3 IgG1 fusion protein, Amevive(TM))...

Gene Therapy Restored Thymic Function In Child With SCID.(severe combined immunodeficiency )
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- Researchers discussed at the American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting, March 18-23, 2001, the details of a patient in whom evidence of normal thymic function and...

Fluorescent Visualization Can Determine Cytomegalovirus Susceptibility.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Fluorescent visualization techniques can be used after stem cell transplantation to quantify T-cell defenses against cytomegalovirus (CMV) infection,...

Interferon Treatments Generate Autoantibodies In Adrenal Cortex.
April 4, 2001... 2001 APR 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - New research performed in Germany indicates interferon-alpha therapy for hepatitis C virus (HCV) generates a low level of adrenal autoantibodies in some...

Antibody 17b May Hold Key To Blocking Viral Entry.(HIV )
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The mechanisms by which the HIV antibody 17b interferes with viral cell entry may aid in the creation of new HIV inhibitors, say researchers in...

Human Trials Of New Vaccine Technique Prove Promising For Allergy Sufferers.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- For years, efforts to develop improved vaccines for asthma and allergies have been thwarted because the vaccines themselves often cause the very symptoms a person is trying to avoid. At the...

Prophylactic Use Of Antihistamines Relieves Skin Reactions From Mosquito Bites.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Individuals sensitive to mosquitoes may find relief from skin reactions by taking antihistamines as a preventive measure, according to a study by researchers in Finland. Researchers from the...

Histamine Dihydrochloride Increases Immune Response.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Maxim Pharmaceuticals (MAXM) announced March 26, 2001, that its lead drug candidate Ceplene(TM) (histamine dihydrochloride)was shown in a preclinical study to significantly increase the expression...

Three Children Apparently Cured Through Unrelated Umbilical-Cord Blood Transplants.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Physicians at the University of California, Los Angeles, announced on April 6, 2001, that three young boys - each born with a defective immune system like the "boy in the bubble" - underwent...

Mild and Chronic Hepatitis Patients Respond Alike To Interferon.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Patients with mild chronic hepatitis C respond at the same rates to interferon therapy as patients with more active chronic disease, researchers suggest....

Transmucosal Drug To Begin Trials In South Africa.(HIV infection)
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc. (HEPH) March 21, 2001, announced it has received clearance from the South African Medicines Control Council (MCC) to initiate testing of a new transmucosal...

Exposure To Household Pets Does Not Increase Sensitization.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - People with allergic rhinitis who are sensitive to pet allergens suffer airway hyperresponsiveness (AHR), but previous pet ownership does not worsen their...

Immunoglobulin E Test Improves Allergen Screening's Accuracy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Pharmacia Diagnostics announced on March 26, 2001, that the ImmunoCAP(TM) allergy blood test has been accepted as a quantitative test by the U.S. Food and Drug Administration (FDA). The test...

Mouse Allergen in Low-Income New York City Apartments Increases Risk.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Mouse allergen is prevalent in inner-city apartments. Children living in these homes are exposed to mouse allergens from infancy, thus increasing their risk for developing allergic sensitivity to...

Antibodies Invoke Cell-Mediated Tumor Killing In Vitro.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- AltaRex Corp. (AXO, ALXFF) of Waltham, Massachusetts, additional data further explaining its clinical demonstration of effective T-cell activation induced by its OvaRex(R) antibody. The in...

Synthetic Enzyme Improves Efficacy Of Interleukin-2 Therapy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Advanced skin and end-stage kidney cancer patients may have a better chance of survival with drugs developed from a new synthetic enzyme that significantly improves the effectiveness of existing...

Rice Bran Extract Arrests Breast Cancer Tumor Cell Growth In Vitro.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- A natural supplement used by thousands to stimulate the immune system can arrest tumor cell growth as well, according to a study reported March 25, 2001, at the 92nd Annual American Academy of...

Study: Emergency Department Response Needs Improvement.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- The findings of a chart review performed to evaluate the management of food allergy in several emergency departments were presented at the American Academy of Allergy, Asthma and Immunology annual...

Antibody Response Depends On Dose Of Inactivated Enterotoxigenic E. coli.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Researchers working in Sweden have developed an oral inactivated Escherichia coli vaccine that boosts circulating antibodies in a dose-dependent manner....

New Egg-Free Flu Vaccine Promising For Those With Egg Allergy.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Researchers in Austria have developed a unique flu vaccine that is made without egg proteins, which can trigger rare, but potentially fatal, allergic reactions in some people. "The development...

Peptide-Based Linking Improves Retention Of Radioisotope In Tumors.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Immunomedics, Inc. (IMMU) announced an advance made by the company's scientists in the attachment of iodine-131 (I-131), a potent therapeutic isotope, to antibodies. The improved technique was...

Immunotherapeutic Antisense Agent Extends Survival.(Genasense)
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Genta, Inc. (GNTA) reported on March 26, 2001, updated results of clinical trials for its immunotherapy drug Genasense(TM) at the annual meeting of the American Association for Cancer Research...

Vaccine Research Results Show Hope For Use Of Dendritic Cells.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- Results from the first-ever study testing the use of dendritic cells in children may offer new hope for a cancer vaccine. The Phase I study results from research at the University of Michigan...

Recombinant Interleukin-11 Not Effective For Refractory Patients.(immune thrombocytopenic purpura)
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Despite its platelet-stimulating effects, recombinant human interleukin-11 (rhIL-11) does not show promising results for the treatment of refractory immune...

CD40-Stimulated Dendritic Cells Boost Immunity, But Not Disease Resistance.(tuberculosis )
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Using dendritic cells stimulated with the cytokine CD40 to vaccinate against tuberculosis enhances immune response to the disease, but does not prevent...

Intestinal Worms May Lower Efficacy Of BCG Vaccine.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Parasites endemic in some parts of the world may have a detrimental effect on tuberculosis immunity, according to a new report in Clinical and Experimental...

Unforeseen Role Of Immune Response In Neurological Repair Could Lead To Vaccine.
April 11, 2001... 2001 APR 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Macrophages and T cells can stop the spread of damage after central nervous system injury, report Weizmann Institute of Science researchers. Immune...

Monoclonal Antibody Shows Anti-Angiogenic Activity.(ABX-IL8)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Abgenix, Inc. (ABGX) announced preclinical study results showing that its investigational human monoclonal antibody, ABX-IL8, blocks angiogenesis and inhibits the growth of human melanoma tumors...

Mechanism For Generating Autoimmunity-Suppressing Cells Identified.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Autoimmune disorders, such as lupus, arthritis, and diabetes, are understood to result from immune cells attacking the body's own cells instead of infectious agents such as viruses and bacteria. In...

Animal Farmers Seem To Be Protected Against Asthma And Nasal Allergies.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Animal farmers seem to be protected against asthma and nasal allergies as compared to the general population. However, farming is associated with an increase in chronic phlegm. So concludes a...

Low-Dose Thalidomide Effective As Salvage Therapy.(for advanced multiple myeloma)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Low doses of thalidomide can preserve its therapeutic effects for advanced multiple myeloma patients while reducing its toxicity, according to researchers...

Adenoviral Gene Transfer Evokes An Immune Response In The Retina.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers at the University of Tubingen in Germany found that intravitreal adenoviral gene transfer evoked an immune response in the retina that was...

Most People With Allergy-Like Symptoms Don't Have Allergies, Study Says.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- A heads-up to people who suffer from allergy-like symptoms: your sniffles and sneezes may not be due to allergies after all. In a recent study of 246 patients, researchers found that nearly...

Canarypox Virus Vector For IV p53 Vaccine Delivery Safe In Rhesus Macaques.
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A potential anti-cancer vaccine has been shown safe at up to 10 times the required dose in rhesus macaques when administered intravenously, and further...

Alemtuzumab Monoclonal Antibody Is Recommended For EU Approval.(for treatment of chronic lymphocytic leukemia)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Millennium & Ilex Partners, LP, announced on March 30, 2001, that the European Medicines Evaluation Agency's (EMEA) Committee on Proprietary Medicinal Products (CPMP) issued a positive opinion to...

Controlling Inflammation May Yield Better Outcomes.(in congestive heart failure treatment)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Controlling chronic inflammation in congestive heart failure patients may improve outcomes and survival, according to a study published in the April 2001 issue of the American Heart Journal. ...

Anti-Cancer Metastasis Compound Headed Into Five Clinical Trials.(GDOO39)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- GLYCODesign, Inc. (GD) is expanding its clinical program to validate the effectiveness of GD0039, its anti-cancer compound. The expansion includes five Phase II clinical trials for multiple cancer...

Methinone Enkephalin Increases Immune Cell Count.(in HIV patients)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Researchers with Vector Medical Technologies, Inc., reported study results demonstrating the company's Methinone enkephalin vaccine increases numbers of T cells and natural killer cells in HIV...

Imiquimod Plus HSV Vaccine Cuts Recurrence Rate 80%.(herpes simplex virus)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The immune modulator imiquimod can dramatically decrease genital outbreaks of herpes simplex virus (HSV), especially when used with HSV vaccine. C.J....

TNF-(alpha) Converting Enzyme Inhibitor To Enter Phase II Clinical Trials.(tumor necrosis alpha as a possible therapy for rheumatoid arthritis, psoriasis, and Crohn's disease)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- DuPont Pharmaceuticals is developing an oral Tumor necrosis factor (TNF) Alpha Converting Enzyme (TACE) inhibitor. TACE is a new target implicated in the inflammatory process that is a factor in...

Nonviral, Electroporation-Assisted Vaccine Produces 100% Tumor Rejection In Mice.(melanoma vaccine)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A plasmid-delivered vaccine consisting of two melanoma tumor antigens enabled mice to completely overcome tumor challenge and even improved survival time...

FDA Grants Immunotherapeutic Orphan Drug Status.(to HspEy for treatment of recurrent respiratory papillomatosis)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- Stressgen Biotechnologies Corp. (SSB) announced March 29, 2001, that the U. S. Food and Drug Administration (FDA) has granted orphan drug status for HspE7, an immunotherapeutic for the treatment of...

Patent Granted For DNA Vaccine Technology.(patent given to Ravax vaccine for rheumatoid arthritis therapy)
April 18, 2001... 2001 APR 18 - (NewsRx.com & NewsRx.net) -- The Immune Response Corp. (IMNR) announced March 30, 2001, that it has received U.S. Patent Number 6,207,645 expanding coverage relating to its immune-based therapy for rheumatoid arthritis,...

Interferon Therapy Reduces Risk In Patients With HCV-Related Cirrhosis.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Patients with hepatitis-C-related liver cirrhosis can reduce their chances of developing liver cancer by taking long-term interferon (IFN) therapy. A...

T-Helper Cytokine Blockers Can Prevent Fungal Infections.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Italy say that drugs that block the action of certain immune cytokines can help prevent infections after stem cell transplantation from...

BCG Vaccine Does Not Lower Risk Of Atopic Disease.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Early vaccination with bacille Calmette-Guerin (BCG) does not decrease the likelihood of atopic disease in children, according to a report in Pediatrics....

Third-Generation Antihistamines Generally Safe In Children.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The evolution of antihistamines has resulted in a class of drugs that are unlikely to sedate children and present low cardiac risk. A.P. Teneick and...

Vitamin A May Enhance Interferon's Effectiveness.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Experiments with human cells conducted by Pennsylvania State University researchers have shed new light on vitamin A's role in the immune response, suggesting that the vitamin's active form may...

RANTES Displaced As Most Potent Chemokine Viral Inhibitor.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Belgium have found a chemokine HIV replication inhibitor far stronger than RANTES, considered by most to be the most potent such replication...

Immunotherapy Agent Against Genital Warts Goes Into Phase II Clinical Trials.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Stressgen Biotechnologies Corp. (SSB) announced on April 10, 2001, that patient enrollment in its Phase II clinical trial investigating HspE7 as a novel immunotherapeutic for genital warts caused...

Early Exposure To Fungi Linked To Wheezing In Infants.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Early exposure to airborne fungal spores may cause respiratory problems in newborns, researchers said at the American Academy of Allergy, Asthma and Immunology (AAAAI) annual meeting, held during...

Peanut Allergens Can Be Passed From Mother To Baby Through Breast Milk.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Protein from peanuts ingested by lactating mothers is secreted into breast milk, and exposure to peanut protein during breastfeeding may sensitize babies at risk of peanut allergy, according to an...

Studies Focus On Dust Mites, Cockroach Allergen.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- While new homes or furniture are dust-free, within a month both are populated with dust mites that come from other areas in which people spend time, such as their vehicles or other people's homes....

Cyclosporin A May Be Treatment Option For Diseases Involving VEGF-Mediated Neovascularization.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Cyclosporin A could be valuable for treating a number of angiogenesis-related diseases, according to a report in The Journal of Experimental Medicine. ...

Avoiding Allergen Exposure In Infancy Reduces The Development Of Asthma.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Children at high-risk for developing asthma are less likely to do so if their exposure to allergy triggers is reduced when they are infants, according to researchers reporting at the American...

Few Children With Frequent Symptoms Use Anti-Inflammatory Medications Regularly.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- The use of preventive asthma medication in U.S. children with symptomatic asthma is related to the child's age, sex, and health care organization, according to an article in the April 2001 issue of...

Dendritic-Glioma Fusion Vaccine Gets Boost From Interleukin-12.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The addition of interleukin-12 (IL-12) to a vaccine of fused dendritic and glioma cells significantly improved survival time for mice with brain tumors,...

Immunization With Dendritic Cells, Complementary DNA Protects Mice From Tumors.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Dendritic cells pulsed with the same type of complementary DNA found in tumor targets show promise as a vaccine candidate for cancer, according to a report...

Anti-Angiogenic Therapy Under Study For Metastatic Disease.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Breast cancer researchers at Rush-Presbyterian-St.Luke's Medical Center in Chicago, Illinois, have begun testing a new therapy that targets the blood vessels that feed breast cancer tumors. ...

Patent Awarded For Novel Cancer Gene, A Target for Development of Multi-Cancer Vaccine.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Dendreon Corporation (DNDN) announced that it has been awarded a patent from the U.S. Patent and Trademark Office for a gene displayed in high incidence in a variety of prevalent cancers, most...

Researchers Identify Novel Gene In IL-10 Family Of Cytokines.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc. (INGN) announced on April 7, 2001, its discovery that the mda-7 gene is a novel member of the interleukin-10 family of cytokines. Sunil Chada, PhD, Introgen,...

Animal Studies Indicate New Approach For Treating End-Stage Skin And Kidney Cancers.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- Advanced skin and end-stage kidney cancer patients may have a better chance of survival with drugs developed from a new synthetic enzyme that significantly improves the effectiveness of existing...

Oral Antigens Induce Inflammation In Gastrointestinal Tract Caused By Eosinophils.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- A Children's Hospital Medical Center of Cincinnati, Ohio, study has definitively linked eosinophilic inflammation to a type of food allergy whose occurrences have risen dramatically in recent...

Interleukin-2 Can Reverse Defective T-Cell Effector Function.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Functioning T cells can become impotent against HIV infected cells despite functioning antigen recognition, a defect that can be reversed by treatment with...

Interferon Somewhat Successful For Treating Benign Tumors In Retina.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Interferon-alpha 2a is effective for treating pediatric patients with benign vascular tumors of the liver. Now researchers say this therapy may reduce the...

Egr-1 Stimulates Macrophage Progenitors.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Deborah W. Heinrich, staff medical writer - Researchers at Temple University in Pennsylvania found that expression of the early growth response gene 1 (Egr-1) in bone marrow cultures results in...

Interferon-(gamma) Therapy Ineffective.
April 25, 2001... 2001 APR 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Despite theoretical promise, researchers in Austria say that interferon (IFN)-(gamma) does not provide significant benefit to idiopathic myelofibrosis...