Immunotherapy Weekly articles from April 1999

Immunotherapy Weekly archives from April 1999

Two New Epitopes For Immunotherapy Discovered.
April 12, 1999... Researchers have discovered two new epitopes that are recognized by a large percentage of the general population. The human carcinoembryonic antigen (CEA) and HER-2/neu are potential target antigens for cytotoxic T lymphocyte (CTL) specific...

Reductions in IL-4 Production May Explain Inhibition.
April 12, 1999... The inhibitory effect that allergy immunotherapy has on IL-4 production and specific IgE response may be a part of the therapy's working mechanism. T. Masamoto and colleagues from the Osaka City University, Japan, conducted a study of 23...

IFN-Alpha Enhances BCG Immunotherapy.
April 12, 1999... A combination therapy is more effective than single therapy in bladder cancer treatment. Y. Luo and colleagues from Harvard University, Massachusetts, evaluated the mechanism by which IFN-alpha enhances BCG-mediated antitumor activity in...

Iscador Adoptive Immunotherapy Controls Tumor Growth.
April 12, 1999... Tumor growth can be significantly inhibited by adoptive immunotherapy using spleen cells that have been activated with Iscador. S. Antony and colleagues from the Amala Cancer Research Center, India, evaluated adoptive immunotherapy with...

Lymphoma Subtype Influences Therapy's Effect.
April 12, 1999... The subtype of the lymphoma and the intensity of CD20 on the tumor cells influences the effectiveness of IDEC-C2B8 immunotherapy. D.T. Nguyen and colleagues from St. Bartholomew's Hospital, England, conducted a study which focused on the...

Mutants, MAbs and Molecular Methodology Facilitate Research.
April 12, 1999... Mutant animal models, monoclonal antibodies (MAbs) and molecular methodology facilitate cancer immunotherapy research. J.C.L. Schuh and colleagues from Immunex Corporation, Washington, reported that rapid advances in the ability to localize...

Combination CSA/ATG Superior to CSA Alone in Aplastic Anemia.
April 12, 1999... The combination of antithymocyte globulin and cyclosporine worked better than did cyclosporine alone in terms of hematologic response in anemia patients undergoing bone marrow transplantation. On behalf of the EBMT Severe Aplastic Anaemia...

Researchers Track Hematopoietic Stem Cells In Vivo.
April 12, 1999... Long-term repopulating stem cells are quiescent in bone marrow 48 hours posttransplant, researchers reported. Sophie M. Lanzkron and colleagues, Johns Hopkins Oncology Center, Baltimore, Maryland, previously demonstrated that they could...

Multisubunit Vaccine: Wave of the Future?
April 12, 1999... Multisubunit immunization may be the wave of the future for tuberculosis vaccines. The development of more effective antituberculosis vaccines would assist in the control of the global problem of infection with Mycobacterium tuberculosis....

Interferon Prevents HBV-Induced Cancer.
April 12, 1999... Interferon therapy may dramatically reduce the incidence of liver cancer in patients with chronic hepatitis B virus infection. A long-term study conducted by researchers from Taiwan's Chang Chung University found that interferon (IFN)...

Vaccines May Provide Treatment Option for Cancer.
April 12, 1999... Vaccines traditionally have been designed to generate immune responses that have a protective effect against specific infections. In the future, however, researchers believe vaccine use will expand from disease prevention to include...

WT1: A New Leukemia and Cancer Antigen.
April 12, 1999... Cancer Vaccines "WT1: A New Leukemia and Cancer Antigen." A. Gaiger, V. Reese, P. Sleath, M.L. Disis and M.A. Cheever. Corixa Corp, Seattle; University of Washington, Seattle; University of Vienna. According to an abstract submitted by...

Autologous Bone Marrow Transplant (BMT) Purged With Anti-CD33 Immunotoxin for Patients with Acute Myeloid Leukemia (AML).
April 12, 1999... Bone Marrow Purging "Autologous Bone Marrow Transplant (BMT) Purged With Anti-CD33 Immunotoxin for Patients with Acute Myeloid Leukemia (AML)." J. Lavoie, R. Belanger, M.J. Robertson, R. Stone, C. Perreault, J. Kassis, L. Busque, R.J....

Immunologic Effects of Granulocyte Macrophage-Colony Stimulating Factor Transfected Autologous Tumor Cell Vaccines in Melanoma.
April 12, 1999... Cancer Vaccines "Immunologic Effects of Granulocyte Macrophage-Colony Stimulating Factor Transfected Autologous Tumor Cell Vaccines in Melanoma." G.S. Hogge, R.R. Dubielzig, M.R. Albertini, N.-S. Sun and E.G. MacEwen. University of...

The Design and Synthesis of Novel Saponin Analogs as Potential Cancer Vaccine Adjuvants and Their Evaluation In an In Vivo Murine Model.
April 12, 1999... Cancer Vaccines "The Design and Synthesis of Novel Saponin Analogs as Potential Cancer Vaccine Adjuvants and Their Evaluation In an In Vivo Murine Model." R.D. May, R.C. Reynolds, A.K. Pathak, L.E. Gundy, Y.Y. Maxuitenko, L.A. Kraus, M.S....

Immunotherapy of Myasthenia Gravis.
April 12, 1999... Myasthenia Gravis (Immunotherapy) "Immunotherapy of Myasthenia Gravis." James E. Blalock. University of Alabama at Birmingham, Birmingham, Alabama. NIH GRANT NUMBER: 5R01AI37670-02. GRANT EXPIRES: March 31, 2002. PRINCIPLE...

Transplant Immunology of IL2 IFN Gamma Double Knockout Mice.
April 12, 1999... Transplant Immunology "Transplant Immunology of IL2 IFN Gamma Double Knockout Mice." Martin S. Zand. University of Rochester, River Campus STA, Rochester, New York 14627. NIH GRANT NUMBER: 1K08AI01641-01. GRANT EXPIRES: August 31,...

Potentiation of Immunosuppressive Efficacy by Combining the Novel Leflunomide Analog, HMR 279, With Microemulsion Cyclosporine in a Rat Lung Transplant Model.
April 12, 1999... Animal Models Hausen, B.; Boeke, K.; Berry, G.J.; Gummert, J.F.; Christians, U.; Morris, R.E. "Potentiation of Immunosuppressive Efficacy by Combining the Novel Leflunomide Analog, HMR 279, With Microemulsion Cyclosporine in a Rat Lung...

Three-Step Radioimmunotherapy With Yttrium-90 Biotin: Dosimetry and Pharmacokinetics in Cancer Patients.
April 12, 1999... Cancer Radiotherapy Cremonesi, M.; Ferrari, M.; Chinol, M.; Stabin, M.G.; Grana, C.; Prisco, G.; Robertson, C.; Tosi, G.; Paganelli, G. "Three-Step Radioimmunotherapy With Yttrium-90 Biotin: Dosimetry and Pharmacokinetics in Cancer...

Boron Neutron Capture Therapy of Brain Tumors: An Emerging Therapeutic Modality.
April 12, 1999... Cancer Therapy Barth, R.F.; Soloway, A.H.; Goodman, J.H.; Gahbauer, R.A.; Gupta, N.; Blue, T.E.; Yang, W.L.; Tjarks, W. "Boron Neutron Capture Therapy of Brain Tumors: An Emerging Therapeutic Modality." Neurosurgery, March...

Correlation Between the Affinity of Flavonoids Binding to the Cytosolic Site of Leishmania tropica Multidrug Transporter and Their Efficiency to Revert Parasite Resistance to Daunomycin.
April 12, 1999... Leishmaniasis (Therapy) Perezvictoria, J.M.; Chiquero, M.J.; Conseil, G.; Dayan, G.; Dipietro, A.; Barron, D.; Castanys, S.; Gamarro, F. "Correlation Between the Affinity of Flavonoids Binding to the Cytosolic Site of Leishmania tropica...

Alternative Oxidase Inhibitors Potentiate the Activity of Atovaquone Against Plasmodium falciparum.
April 12, 1999... Malaria (Therapy) Murphy, A.D.; Langunnasch, N. "Alternative Oxidase Inhibitors Potentiate the Activity of Atovaquone Against Plasmodium falciparum." Antimicrobial Agents and Chemotherapy, March 1999;43(3):651-654. According to the...

Fluoroquinolone Action Against Clinical Isolates of Mycobacterium tuberculosis: Effects of a C-8 Methoxyl Group on Survival in Liquid Media and in Human Macrophages.
April 12, 1999... TB (Therapy) Zhao, B.Y.; Pine, R.; Domagala, J.; Drlica, K. "Fluoroquinolone Action Against Clinical Isolates of Mycobacterium tuberculosis: Effects of a C-8 Methoxyl Group on Survival in Liquid Media and in Human Macrophages."...

IL-10-Treated DCs Induce Antigen-Specific Anergy.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Interleukin-10 (IL-10)-treated human dendritic cells (DCs) induce a tumor-antigen-specific anergy which results in a failure of CD8(+) T cells to lyse tumor cells. These findings support earlier...

New Peptide Suggests Potential Immunotherapy Agents.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Stimulation with peptide analogs may be a potential immunotherapeutic agent. M.D. Burton and colleagues from Monash University School of Medicine, Australia, discovered a peptide that may help...

Immune Regulation in the Brain is Site-Specific.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Neurochemicals affect immune function differently in different regions of the brain. Although research has shown that neurotransmitters and neuropeptides affect immune function in vitro and in...

Bacterial Infection Can Mediate Tumor Regression.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Four patients with tumor regression can thank bacterial infections. A.P. Bowles and colleagues from the University of Mississippi analyzed the antineoplastic properties of bacteria ("Long-Term...

CD4-Binding Glycoprotein Inhibits Apoptosis.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Gp17 may be a new immune-modulating factor against tumors and infections. M. Gaubin and colleagues from CNRS, Villejuif, France, expanded previous research to determine the function of...

CD34(+) Cell System May Improve Future of Immunotherapy.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A system that uses CD34(+) cells may have potential for improving immunotherapy. Although current in vitro culture systems allow the generation of human dendritic cells (DCs), the output of...

Review of IFN Studies Provides Interesting New Data.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Testing for serum HCV RNA six months following interferon therapy appears to be a useful predictor of long-term response in patients with chronic hepatitis C. Researcher Calogero Camma and...

Heat Inactivation Increases HIV Antigenicity.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Heat inactivation appears to increase the antigenicity of HIV, possibly by exposing previously hidden epitopes. The finding comes from a research team using an all-but-abandoned approach to...

Ribavirin Promotes Type-1 Cytokine-Mediated Response.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Ribavirin appears to promote Type 1 cytokine-mediated immune response, which could explain its ability to boost interferon activity in patients with chronic hepatitis C virus. The therapeutic...

Autoantigen May Be Clinically Relevant in HCV Treatment.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Epitope mapping of cytochrome P4502D6 autoantigen may be of clinical significance in chronic hepatitis C virus patients given interferon. Cytochrome P450 2D6 (CYP2D6) has been documented as the...

Idiotype Immunization May Be Beneficial.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Stem cell transplantation and immunizations of intravenous idiotype-pulsed autologous dendritic cells may be helpful in multiple myeloma patients. The idiotype (Id) determinant on the multiple...

Vaccine Might Work Against Peanut Allergy.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Researchers said they had taken the first step toward making a vaccine against peanut allergy, the most common cause of death from food allergies. They said they used DNA from peanuts to help...

Chemical Contaminants May Inhibit White Blood Cells.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Researchers in Kentucky have demonstrated that a class of common chemical contaminants known as butyltins disrupt the function of critical human immune cells. The scientists also said...

Immunology Technology Advanced.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Nanogen, Inc., San Diego, California, announced that advances in the company's single nucleotide polymorphism discrimination technology were published in the April 1999 issue of Nature Biotechnology....

Data Supporting Malaria and Hepatitis Vaccine Development Reported.
April 19, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Epimmune Inc., San Diego, California, announced that it has published data concerning its approach to vaccine development in three journals. The data were reported in Vaccine (Franke et al., "Pan...

WT1: A New Leukemia and Cancer Antigen.
April 19, 1999... Cancer Vaccines "WT1: A New Leukemia and Cancer Antigen." A. Gaiger, V. Reese, P. Sleath, M.L. Disis and M.A. Cheever. Corixa Corp, Seattle; University of Washington, Seattle; University of Vienna. (CW HENDERSON PUBLISHER...

Autologous Bone Marrow Transplant (BMT) Purged With Anti-CD33 Immunotoxin for Patients with Acute Myeloid Leukemia (AML).
April 19, 1999... Bone Marrow Purging "Autologous Bone Marrow Transplant (BMT) Purged With Anti-CD33 Immunotoxin for Patients with Acute Myeloid Leukemia (AML)." J. Lavoie, R. Belanger, M.J. Robertson, R. Stone, C. Perreault, J. Kassis, L. Busque, R.J....

Immunologic Effects of Granulocyte Macrophage-Colony Stimulating Factor Transfected Autologous Tumor Cell Vaccines in Melanoma.
April 19, 1999... Cancer Vaccines "Immunologic Effects of Granulocyte Macrophage-Colony Stimulating Factor Transfected Autologous Tumor Cell Vaccines in Melanoma." G.S. Hogge, R.R. Dubielzig, M.R. Albertini, N.-S. Sun and E.G. MacEwen. University of...

The Design and Synthesis of Novel Saponin Analogs as Potential Cancer Vaccine Adjuvants and Their Evaluation In an In Vivo Murine Model.
April 19, 1999... Cancer Vaccines "The Design and Synthesis of Novel Saponin Analogs as Potential Cancer Vaccine Adjuvants and Their Evaluation In an In Vivo Murine Model." R.D. May, R.C. Reynolds, A.K. Pathak, L.E. Gundy, Y.Y. Maxuitenko, L.A. Kraus, M.S....

Immunotherapy of Myasthenia Gravis.
April 19, 1999... Myasthenia Gravis (Immunotherapy) "Immunotherapy of Myasthenia Gravis." James E. Blalock. University of Alabama at Birmingham, Birmingham, Alabama. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 5R01AI37670-02. GRANT...

Transplant Immunology of IL2 IFN Gamma Double Knockout Mice.
April 19, 1999... Transplant Immunology "Transplant Immunology of IL2 IFN Gamma Double Knockout Mice." Martin S. Zand. University of Rochester, River Campus STA, Rochester, New York 14627. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER:...

Potentiation of Immunosuppressive Efficacy by Combining the Novel Leflunomide Analog, HMR 279, With Microemulsion Cyclosporine in a Rat Lung Transplant Model.
April 19, 1999... Animal Models Hausen, B.; Boeke, K.; Berry, G.J.; Gummert, J.F.; Christians, U.; Morris, R.E. "Potentiation of Immunosuppressive Efficacy by Combining the Novel Leflunomide Analog, HMR 279, With Microemulsion Cyclosporine in a Rat Lung...

Three-Step Radioimmunotherapy With Yttrium-90 Biotin: Dosimetry and Pharmacokinetics in Cancer Patients.
April 19, 1999... Cancer Radiotherapy Cremonesi, M.; Ferrari, M.; Chinol, M.; Stabin, M.G.; Grana, C.; Prisco, G.; Robertson, C.; Tosi, G.; Paganelli, G. "Three-Step Radioimmunotherapy With Yttrium-90 Biotin: Dosimetry and Pharmacokinetics in Cancer...

Boron Neutron Capture Therapy of Brain Tumors: An Emerging Therapeutic Modality.
April 19, 1999... Cancer Therapy Barth, R.F.; Soloway, A.H.; Goodman, J.H.; Gahbauer, R.A.; Gupta, N.; Blue, T.E.; Yang, W.L.; Tjarks, W. "Boron Neutron Capture Therapy of Brain Tumors: An Emerging Therapeutic Modality." Neurosurgery, March...

Correlation Between the Affinity of Flavonoids Binding to the Cytosolic Site of Leishmania tropica Multidrug Transporter and Their Efficiency to Revert Parasite Resistance to Daunomycin.
April 19, 1999... Leishmaniasis (Therapy) Perezvictoria, J.M.; Chiquero, M.J.; Conseil, G.; Dayan, G.; Dipietro, A.; Barron, D.; Castanys, S.; Gamarro, F. "Correlation Between the Affinity of Flavonoids Binding to the Cytosolic Site of Leishmania tropica...

Alternative Oxidase Inhibitors Potentiate the Activity of Atovaquone Against Plasmodium falciparum.
April 19, 1999... Malaria (Therapy) Murphy, A.D.; Langunnasch, N. "Alternative Oxidase Inhibitors Potentiate the Activity of Atovaquone Against Plasmodium falciparum." Antimicrobial Agents and Chemotherapy, March 1999;43(3):651-654. (CW HENDERSON...

Fluoroquinolone Action Against Clinical Isolates of Mycobacterium tuberculosis: Effects of a C-8 Methoxyl Group on Survival in Liquid Media and in Human Macrophages.
April 19, 1999... TB (Therapy) Zhao, B.Y.; Pine, R.; Domagala, J.; Drlica, K. "Fluoroquinolone Action Against Clinical Isolates of Mycobacterium tuberculosis: Effects of a C-8 Methoxyl Group on Survival in Liquid Media and in Human Macrophages."...

Naked DNA Cytokine Delivery Has Immune Modulating Effects.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Tumor tissue may be a promising target for direct cytokine gene transfer with nonviral vectors. T. Nomura and colleagues from Kyoto University, Japan, examined the antitumor effect of direct...

Combination Therapy goes to Trial.(interferon, interleukin-2 and cisplatin)
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Interferon does not improve the activity of cisplatin/interleukin-2 therapy in melanoma patients. T. Dorval and colleagues from the Institute Curie, Paris, France, evaluated the response rate,...

Gene-Gun Therapy Pulls Trigger on Cancer.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Gene-gun mediated cytokine gene therapy may be a safe in vivo anticancer therapeutic. A.L. Rakhmilevich and colleagues from the University of Wisconsin compared a gene-delivery method of cytokine...

HCC Immunotherapy Could Target MAGE Gene Family.(hepatocellular carcinoma,)
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Because MAGE gene expression is common in hepatocellular carcinoma (HCC), immunotherapy targeting MAGE peptides may be feasible. K. Tahara and colleagues from Kyushu University, Japan, studied...

NY-ESO-1 Expression Could Be Exploited for Immunotherapy.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- NY-ESO-1 gene expression may be a viable lung cancer immunotherapy target. L. Lee and colleagues from the U.S. National Cancer Institute, Bethesda, Maryland, evaluated the frequency of NY-ESO-1...

Short-Term Interleukin Expression Attacks Cancer Cells.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The activation of invasive T lymphoma cells to express cytokines results in antitumor and immunotherapeutic re-actions. E. Voronov and colleagues from the Ben Gurion University Negev, Israel,...

Trials Suggest IFN-(alpha) May Have Merit in Cancer Treatment.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Anticancer regimens that include interferon-alpha (IFN-alpha) may prolong patient survival. M. Hernberg and colleagues from the University of Helsinki, Finland, performed a meta-analysis...

T. longibrachiatum Acquired Via Gastrointestinal Tract.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The gastrointestinal tract may have been the portal of entry for a fatal, disseminated Trichoderma longibrachiatum infection in a bone marrow transplant recipient. The case is the fifth report...

HGV Doesn't Impact IFN Efficacy.(hepatitis G virus, interferon)
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Approximately one out of five chronic hepatitis C virus patients who have been treated with either interferon or liver transplantation have hepatitis G virus coinfection, according to a study from...

Transcutaneous Immunization Advances in Animal Studies.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- An immunogenic cream may replace needles for administration of many vaccines. The technique is called transcutaneous immunization or TCI. It uses bacterial ADP-ribosylating exotoxins (bAREs) to...

Type 1 and 2 Cytokines Involved in TB Reactivation.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Tuberculosis reactivation is associated with a shift from type 1 to type 2 cytokines, according to a report from Ohio State University. The pattern of cytokines produced by T cells from mice with...

Cytokine Assay Aids Evaluation in Endemic Areas.(diagnosing tuberculosis)
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A whole blood cytokine assay appears to be useful for epidemiologic evaluation in areas where tuberculosis is endemic, according to a report from Uganda. It has been proposed that "type 1"...

Phase I/II Study Shows rHuIL-12 Not Effective.(recombinant human interleukin-12)
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Recombinant human interleukin-12 does not appear to be an adequate therapy for chronic hepatitis C, according to a phase I/II study from Germany. Researchers determined that the interleukin was...

Drug's Protective Effect on Lymphocytes Reported.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- According to Maxim Pharmaceuticals, Inc., data reported at the 90th annual meeting of the American Association of Cancer Research (AACR) in Philadelphia, Pennsylvania, provide expanded evidence of...

Immune System Process Could Halt Progress of Cirrhosis.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Results of animal laboratory studies conducted at the University of Pittsburgh's Thomas E. Starzl Transplantation Institute dispel the notion that interleukin-6 (IL-6) causes liver fibrosis or...

New Coating Process May Prevent Implant Rejection.
April 26, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- New research suggests that the metaphor of a lock and key to describe how the body uses specific cell-protein interactions to promote healing offers a nifty blueprint for making medical implants that...

Intravesical Bacillus Calmette-Guerin Administration Enhances BCG-Activated-Killer Cells During the Course of Therapy.
April 26, 1999... Cancer Immunotherapy "Intravesical Bacillus Calmette-Guerin Administration Enhances BCG-Activated-Killer Cells During the Course of Therapy." N. Abdel Tawab, S. Brandau, P. Maille, S. Zamattio, A. Belhle and D. Chopin. Centre de Recherche...

Cytotoxicity of Murine Peritoneal Macrophages and Human Monocytes against Ovarian Cancer Cells Expressing Mutant p53.(Abstract)
April 26, 1999... Cancer Gene Therapy "Cytotoxicity of Murine Peritoneal Macrophages and Human Monocytes against Ovarian Cancer Cells Expressing Mutant p53." A.H. Klimp, S. Withoff, E.G.E. De Vries, G.L. Scherphof and T. Daemen. Departments Physiological...

Adoptive Immunotherapy for Post Transplant EBV Lymphoma.(Epstein-Barr virus)(Abstract)
April 26, 1999... Cancer Immunotherapy "Adoptive Immunotherapy for Post Transplant EBV Lymphoma." Kenneth G. Lucas. University of Alabama at Birmingham, Birmingham, Alabama. (CW HENDERSON PUBLISHER www.newsfile.com) -- GRANT NUMBER: 5R01CA75566-03....

Recombinant Tumor Vaccine - CATBRM.
April 26, 1999... Cancer Vaccines "Recombinant Tumor Vaccine - CATBRM." Albert F. Lobuglio. University of Alabama at Birmingham, Birmingham, Alabama. (CW HENDERSON PUBLISHER www.newsfile.com) -- GRANT NUMBER: 5U01CA61397-06. GRANT EXPIRES: July 31,...

Immunogene Therapy by Direct Delivery of Plasmid DNA Using In Vivo Electroporation.(Abstract)
April 26, 1999... Immunogene Therapy "Immunogene Therapy by Direct Delivery of Plasmid DNA Using In Vivo Electroporation." R. Heller, M.L. Lucas, L. Heller, C. Pottinger, R. Gilbert and M.J. Jaroszeski. Department of Surgery, College of Medicine, University...

Induction of Specific CD8(+) T-Lymphocyte Responses Using a Human Papillomavirus-16 E6/E7 Fusion Protein and Autologous Dendritic Cells.(Abstract)
April 26, 1999... Cancer Vaccines Murakami, M.; Gurski, K.J.; Marincola, F.M.; Ackland, J.; Steller, M.A. "Induction of Specific CD8(+) T-Lymphocyte Responses Using a Human Papillomavirus-16 E6/E7 Fusion Protein and Autologous Dendritic Cells." Cancer...

Phase II Prostate Cancer Vaccine Trial: Report of a Study Involving 37 Patients With Disease Recurrence Following Primary Treatment.
April 26, 1999... Cancer Vaccines Murphy, G.P.; Tjoa, B.A.; Simmons, S.J.; Ragde, H.; Rogers, M.; Elgamal, A.; Kenny, G.M.; Troychak, M.J.; Salgaller, M.L.; Boynton, A.L. "Phase II Prostate Cancer Vaccine Trial: Report of a Study Involving 37 Patients With...

CD40-Activated B-Cell Chronic Lymphocytic Leukemia Cells for Tumor Immunotherapy: Stimulation of Allogeneic Versus Autologous T Cells Generates Different Types of Effector Cells.(Abstract)
April 26, 1999... Chronic Lymphocytic Leukemia Buhmann, R.; Nolte, A.; Westhaus, D.; Emmerich, B.; Hallek, M. "CD40-Activated B-Cell Chronic Lymphocytic Leukemia Cells for Tumor Immunotherapy: Stimulation of Allogeneic Versus Autologous T Cells Generates...

Curative Treatment of Experimental Autoimmune Thyroiditis by in vivo Administration of Plasmid DNA Coding for Interleukin-10.(Abstract)
April 26, 1999... Gene Delivery Batteux, F.; Trebeden, H.; Charreire, J.; Chiocchia, G. "Curative Treatment of Experimental Autoimmune Thyroiditis by in vivo Administration of Plasmid DNA Coding for Interleukin-10." European Journal of Immunology, March...

Cu-67- Versus I-131-Labeled Lym-1 Antibody: Comparative Pharmacokinetics and Dosimetry in Patients With Non-Hodgkin's Lymphoma.(Abstract)
April 26, 1999... Lymphoma Denardo, G.L.; Kukis, D.L.; Shen, S.; Denardo, D.A.; Meares, C.F.; Denardo, S.J. "Cu-67- Versus I-131-Labeled Lym-1 Antibody: Comparative Pharmacokinetics and Dosimetry in Patients With Non-Hodgkin's Lymphoma." Clinical Cancer...