Vaccine Weekly articles from September 2004

Vaccine Weekly archives from September 2004

Streptococcus pneumoniae neuraminidase protects against otitis media.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Immunization with native or recombinant Streptococcus pneumoniae neuraminidase affords protection in the chinchilla otitis media model. According to recent research from the United States,...

Immunization protects dopaminergic neurons in model of Parkinson disease.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson disease. According to a study from the United States, "Degeneration of the nigrostriatal dopaminergic pathway,...

No evidence found linking encephalopathy to pertussis vaccination.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have not found any convincing evidence to link encephalopathy with pertussis vaccination. "To assess whether pertussis-containing vaccines cause encephalitis or encephalopathy, the...

Killed nonencapsulated cells protect mice against pneumococcal colonization.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Killed nonencapsulated cells given intranasally with a nontoxic adjuvant protected mice against pneumococcal colonization of the nasopharynx and middle ear. According to a study from the United...

Prion protein domains elicit antibody responses against native molecule.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have identified two immunogenic domains of the prion protein PrP, which activate class II-restricted T cells and elicit antibody responses against the native molecule. "Recent reports...

Challenges in the search for HIV vaccine outlined.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers outline challenges in the search for an HIV vaccine in a recent issue of the European Journal of Epidemiology. "Considerable progress has been made over the past several years in the...

DNA prime-MVA boost HIV vaccine tailored for eastern and central Africa.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed a DNA prime-MVA boost HIV vaccine tailored for eastern and central Africa. According to a study from England, "For the development of human immunodeficiency virus type 1...

T cell-based control of SIV replication in AIDS vaccine trial reported.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers report cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial. "Recently, encouraging AIDS vaccine trials in macaques have...

Quaternary ammonium compounds exhibit adjuvant effect in murine model.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Quaternary ammonium compounds exhibit an adjuvant effect in a murine model. "It has been suggested that occupational exposure to quaternary ammonium compounds (QACs) may promote the development of...

Tolerance in T cells accompanied by effector function in lymphoid organs.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Oral tolerance in T cells is accompanied by induction of effector function in lymphoid organs after systemic immunization. "The physiological ramifications of oral tolerance remain poorly...

Amyloid accumulation in Alzheimer disease is response to chronic stress.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Amyloid accumulation in Alzheimer disease is a response to chronic stress. "Amyloid deposition within cerebral vessels, or cerebral amyloid angiopathy (CAA), is common in advanced age and even more...

Testing of Alzheimer vaccines needed in non-murine models.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Alzheimer vaccines must be thoroughly tested in non-murine animal models before trials begin in humans. According to a study from Australia and the United States, "Recent clinical and...

Prostaglandin E[subscript]2 receptors up-regulated in peritoneal macrophages.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Prostaglandin E[subscript]2 receptors EP2 and EP4 are up-regulated in peritoneal macrophages and joints of pristane-treated mice and modulate TNF-alpha and IL-6 production. "Prostaglandin...

Farnesyl transferase inhibitors show promise as therapies for breast cancer.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Farnesyl transferase inhibitors show promise as targeted therapies for breast cancer. According to recent research published in the journal Endocrine-Related Cancer, "The ras family of...

Peptides inducing immune responses in breast cancer patients identified.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have identified HER2/neu-derived peptides capable of inducing both cellular and humoral immune responses in HLA-A24 positive breast cancer patients. "HRE2/neu-specific cellular and...

Tamoxifen and soluble tumor-associated antigens suppress breast cancer.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Treatment with tamoxifen and soluble tumor-associated antigens stimulate T- and B-lymphocyte responses to breast cancer tumors. According to recent research published in the journal Oncology...

Vaccine protects mice against virulent Brucella melitensis.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Oral vaccination with Brucella melitensis WR201 protects mice against intranasal challenge with virulent Brucella melitensis 16M. "Human brucellosis can be acquired from infected animal tissues by...

Pharma company reports second quarter 2004 results.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Point Therapeutics, Inc., (NASDAQ: POTP) reported results for the fiscal quarter and 6 months ended June 30, 2004. During the second quarter of 2004, Point achieved the following key milestones:...

Generics producer granted rights for fluconazole, intends to file antiretroviral.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Ranbaxy Laboratories Limited (RLL) announced that the company has received approval from the U.S. Food and Drug Administration (FDA) to manufacture and market Fluconazole Tablets and Oral Suspension....

Biotechnology company and ViroTarg sign anticancer license agreement.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Psiron Ltd signed a worldwide license agreement with ViroTarg Pty Limited, and its major shareholders, The University of Newcastle Research Associates (TUNRA) Ltd and SciCapital Pty Limited. The...

Pharma company announces publication of study examining Talabostat.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Point Therapeutics, Inc., (NASDAQ: POTP) announced that a study investigating its lead product candidate talabostat (PT-100) has been published in the August edition of Cancer Research. The study...

Antigen-loading strategies of dendritic cells for cancer vaccines compared.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Investigators compare antigen-loading strategies of dendritic cells for tumor immunotherapy in a recent issue of the Journal of Immunotherapy. "Dendritic cells (DCs) loaded with antigens can...

CD4+ responses identified in patient vaccinated with NY-ESO-1.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have identified immunodominant CD4+ responses in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant. According to recent research from Australia, "There is...

Epithelial cancer-related antigens applicable for peptide-based immunotherapy.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Investigators review the expression of epithelial cancer-related antigens in hematologic malignancies applicable for peptide-based immunotherapy in a recent issue of the Journal of Immunotherapy. ...

Exosomes from plasmacytoma cells show promise as tumor vaccine.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Exosomes from plasmacytoma cells show promise as a tumor vaccine. "Exosomes are membrane-bound vesicles derived from multivesicular bodies that are externalized by cells through fusion with the...

Monoclonal antibodies recognize idiotypic immunoglobulins of lymphoma cells.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Human monoclonal antibodies produced in transgenic BABK kappa,lambda mice recognize idiotypic immunoglobulins of human lymphoma cells. According to a study from Spain, "Clonal idiotypic...

Thymus-leukemia antigen acts as tumor-specific antigen.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers are investigating thymus-leukemia antigen (TL) as a major histocompatibility complex (MHC) class lb molecule and tumor-specific antigen. According to recent research from Japan, "Mouse...

Viral chemokine fusions trigger antitumor immunity independent of chemotaxis.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis. "The ideal vaccine carrier should be able to target antigen...

Trypomastigote challenge of T. cruzi infected mice reduces parasitemia.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- A challenge of Trypanosoma cruzi chronically infected mice with trypomastigotes activates the immune system and reduces subpatent parasitemia levels. According to recent research from Brazil,...

Varicella vaccine reduces contagiousness of chickenpox.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Children and adolescents who have received the varicella (chickenpox) vaccine and contract varicella are about half as contagious as those who have not been vaccinated, according to a new study. ...

V. cholerae polysaccharide fragments are immunogenic in mice.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Synthetic fragments of Vibrio cholerae O1 inaba O-specific polysaccharide bound to a protein carrier are immunogenic in mice but do not induce protective antibodies. According to a study from the...

Antibodies to Cryptococcus neoformans infection are nonprotective.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Antibodies produced in response to Cryptococcus neoformans pulmonary infection in mice have characteristics of nonprotective antibodies. According to published research from the United States,...

Gender differences exist in cytokine secretion from cytomegalovirus infection.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Gender differences exist in cytokine secretion resulting from cytomegalovirus infection. According to recent research from the United States, "Cell-mediated memory immune responses to viral antigens...

CD8+ T-cell immunity to cytomegalovirus reviewed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers review CD8+ T-cell immunity to cytomegalovirus in a recent issue of Human Immunology. "Cytomegalovirus is arguable the most immunodominant antigen that is encountered by the human...

Cytomegalovirus-specific cellular immune responses reviewed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers review cytomegalovirus-specific cellular immune responses in a recent issue of Human Immunology. According to recent research from Switzerland, "A large percentage of healthy...

Lentiviral vector encoding cytomegalovirus protein identifies epitopes.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Investigators have used a lentiviral vector encoding a human cytomegalovirus chimeric IE1-pp65 protein for epitope identification in HLA-transgenic mice. "H2-deleted, HLA-A2, or HLA-B7 transgenic...

Progress being made toward developing cytomegalovirus peptide vaccine.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Progress is being made toward developing a cytomegalovirus peptide vaccine. "Cytomegalovirus disease still remains a major cause of morbidity and mortality in hematopoietic stem cell transplantation...

Monocyte activation test for parenteral drug contaminants developed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed a monocyte activation test for pro-inflammatory and pyrogenic contaminants of parenteral drugs. "An optimized test designed for an in vitro monocyte activation test for...

Positive results reported: Electroporation-enabled DNA delivery sans anesthesia.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp.Bernie Hertel, +1-858-410-3101 Genetronics Biomedical Corp. (GEB), a late-stage developer of cancer and other therapies using electroporation-enabled delivery of drugs,...

Tobacco promising "factory" for biopharmaceuticals.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- The economics of producing biopharmaceuticals from transgenic plants such as tobacco is still a roadblock to producing large quantities of urgently needed medicines, especially for people in...

Entamoeba lectin epitopes recognized by human IgA antibodies identified.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have identified the Entamoeba histolytica galactose-inhibitable lectin epitopes recognized by human immunoglobulin A antibodies following cure of amebic liver abscess. "Immunity to...

Immunotherapy company's second-quarter revenue dips.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Corixa Corp. (CRXA), a developer of immunotherapeutics, announced financial results for the second quarter ended June 30, 2004. For the second quarter of 2004 Corixa reported total revenue of $5.8...

Maker of COLD-EEZE reports second quarter results.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- The Quigley Corporation (Nasdaq: QGLY) reported net sales of $6.9 million for the second quarter of 2004, compared to $7.0 million reported for the same period in 2003. For the 6-months ended June...

Hsp60 plus copurified lipopolysaccharide protects against F. tularensis.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Protection afforded by heat shock protein 60 (Hsp60) from Francisella tularensis is due to copurified lipopolysaccharide. "Heat shock proteins (Hsps) have attracted significant attention as...

Link between Guillain-Barre syndrome and hepatitis A vaccine reported.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers report a possible association between hepatitis A vaccination and Guillain-Barre syndrome. According to recent research from Israel, "We report a case of Guillain-Barre syndrome in a...

Inactivated hepatitis A vaccine effective in children with liver disease.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- An inactivated hepatitis A vaccine was effective in children with chronic liver disease. "One and 6 months after vaccination with hepatitis A virus vaccine (HAVRIX 720 Junior), immunologic...

Hepatitis B vaccine plus lamivudine did not eliminate viral DNA.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Combined recombinant hepatitis B vaccine and lamivudine therapy did not eliminate viral DNA in a patient with chronic hepatitis B. "We report the first case of a woman having chronic hepatitis B...

Vaccination blitz: 13,312 inoculations over 2 1/2 days.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Doctors and nurses vaccinated 13,312 children around Louisiana during a three-day drive. That was more than 12% above last year's 3-day total of 11,846. The public health region centered in...

Method to monitor T cell responses during vaccine studies developed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have developed a method for monitoring T cell responses during vaccine studies. According to published research from Switzerland, "The authors developed a standardized approach for...

Methods to recover cells from ELISPOT immunoassay developed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed methods to recover cells from the ELISPOT immunoassay. "The enzyme-linked immunospot (ELISPOT) assay is a highly sensitive and reproducible method for quantifying T...

Tetramers with influenza hemagglutinin and EBV epitopes detect CD4+ T cells.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- MHC class II tetramers containing influenza hemagglutinin and Epstein-Barr virus (EBV) EBNA1 epitopes detect reliably specific CD4+ T cells in healthy volunteers. According to recent research from...

VIG product submitted for FDA approval.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Cangene announced that it has submitted a biological license application (BLA) to the U.S. Food and Drug Administration (FDA) for Cangene's Vaccinia hyperimmune globulin (VIG). Cangene's...

Cytokine staining to quantify specific T cell responses in macaques optimized.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have optimized intracellular cytokine staining for the quantitation of antigen-specific CD4+ T cell responses in rhesus macaques. According to a study from the United States, "Standard...

Human B cells are alternative source of efficient antigen-presenting cells.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Human B cells that hyperexpress a triad of costimulatory molecules via avipox-vector infection are an alternative source of efficient antigen-presenting cells. "Dendritic cells (DCs) are the most...

CDC: Flu shot effective more than half of the time.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Last season's influenza vaccine was effective more than half the time, despite fears the shot was not an exact match for the flu strain that dominated the United States, the government says. A...

Company delivers first million doses of Fluvirin vaccine to U.S. distributors.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Chiron Corp. (CHIR) announced it has delivered the first 1 million doses of its Fluvirin influenza vaccine to U.S. distributors in preparation for the upcoming influenza season. The company expects...

First influenza vaccine shipped to healthcare providers.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Aventis has started shipment of its influenza vaccine (Fluzone, Influenza Virus Vaccine), meeting the company's goal to provide Fluzone vaccine to customers to allow healthcare providers to plan...

Reassortment with avian influenza virus attenuates influenza virus.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Reassortment with an avian influenza virus attenuates a human H9N2 influenza virus in a mammalian host. According to published research from Japan and China, "In order to develop a surrogate virus...

Antigenic and genetic evolution of influenza virus mapped.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have mapped the antigenic and genetic evolution of the influenza virus. "The antigenic evolution of influenza A (H3N2) virus was quantified and visualized from its introduction into...

Lyme borreliosis from infection to autoimmunity reviewed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Lyme borreliosis, from infection to autoimmunity, is reviewed in a recent issue of Clinical Microbiology and Infection. "Lyme borreliosis in humans is an inflammatory disease affecting multiple...

CDC: Measles cases lowest since 1912.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Measles cases are at the lowest levels in nearly a century, the U.S. government says. There were only 216 cases of the virus in the 3 years from 2001-03, the U.S. Centers for Disease Control and...

Conformational flexibility in measles virus nucleocapsids visualized.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have visualized conformational flexibility in recombinant measles virus nucleocapsids by cryo-negative stain electron microscopy and real-space helical reconstruction. "Measles virus is...

Efficacy of melanoma vaccines enhanced in the absence of B lymphocytes.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have enhanced the efficacy of melanoma vaccine in the absence of B lymphocytes. According to recent research from the United States, "Provoking a specific cellular immune response...

Mucosal vaccine against serogroup B meningococci developed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Bactericidal antibodies and cellular immunity were induced following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin. "Conjugated...

Effect of microsphere formulation on protein immunogenicity studied.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the effect of PLA and PLGA microsphere formulation on protein immunogenicity. "The entrapment of beta-galactosidase (Escherichia coli) in PLA and PLGA microspheres...

Nasal antigen delivery augments antigen-specific T-cell clonal expansion.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Nasal delivery of antigen with the B subunit of Escherichia coli heat-labile enterotoxin augments antigen-specific T-cell clonal expansion and differentiation. "Escherichia coli heat-labile...

Method to quantify mumps virus RNA by one-step real-time RT-PCR developed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed a method for the rapid and quantitative detection of mumps virus RNA by one-step real-time RT-PCR. "We developed a new TaqMan-based one-step real-time reverse...

NadA diversity and carriage in Neisseria meningitidis reviewed.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists review nadA diversity and carriage in Neisseria meningitidis in a recent issue of Infection and Immunity. According to recent research from Italy, "NadA is a novel vaccine candidate...

Immunodominant epitopes from Paracoccidioides brasiliensis identified.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral...

Antibody response by P. gingivalis and F. nucleatum modulated.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists report the modulation of the antibody response by Porphyromonas gingivalis and Fusobacterium nucleatum in a mouse model in a recent issue of Oral Microbiology and Immunology. According...

Caudill named chairman, CEO Gordon also named president at biopharm company.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- VaxGen Inc. (VXGNE) announced that Randall L-W. Caudill, DPhil, has been named chairman of the board, and that William D. Young has resigned as a director. The company also announced that Lance K....

Cerus appoints William J. Dawson as vice president, finance and CFO.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Cerus Corp. (CERS) announced the appointment of William J. Dawson as vice president, finance and CFO, effective August 9, 2004. Dawson will succeed Gregory W. Schafer, who has served as chief...

Epitope of Bordetella pertussis protein characterized.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists have determined the epitope structure of the Bordetella pertussis protein P.69 pertactin, which is a major vaccine component and protective antigen. According to a study from the...

Expression of pertussis toxin S1 subunit protects against pertussis toxin.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Expression of a C terminally truncated form of pertussis toxin S1 subunit effectively induces protection against pertussis toxin following DNA-based immunization. "Four plasmids encoding different...

Mutated Sabin poliovirus shed after administration of oral poliovirus vaccine.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Sabin poliovirus type 3 containing the nucleotide 472 uracil-to-cytosine point mutation is shed after administration of oral poliovirus vaccine. According to recent research published in the Journal...

European patent for Vaxfectin adjuvant granted to biopharmaceutical company.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Vical Incorporated (VICL) announced the grant of European Patent No. EP1165140, covering vaccination with a novel adjuvant, Vaxfectin. Specific claims include compositions and methods for gene-based...

Vaccine against LH-releasing fusion protein does not increase prostate cancer.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Immunization against luteinizing hormone (LH)-releasing fusion proteins does not increase prostate cancer in the transgenic adenocarcinoma mouse prostate model. "This study was undertaken to test...

The use of rabies immune globulin by emergency physicians.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- A scientist reviews the use of rabies immune globulin by emergency physicians in a recent issue of the Journal of Emergency Medicine. According to a study from the United States, "We sought to...

Nasal IgA important for protection from respiratory syncytial virus infection.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Nasal IgA antibodies are important for protection from natural respiratory syncytial virus infection in adults. "Virus-specific nasal immunoglobulin (Ig) A and serum antibody titers in 67...

Two antigenic epitopes on the SARS-CoV spike protein are identified.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Two antigenic epitopes on severe acute respiratory syndrome-coronavirus (SARS-CoV) have been identified. According to a study from the People's Republic of China, "The spike (S) protein of severe...

Immune responses to killed Salmonella vaccine investigated.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Scientists report results of an investigation on cell-mediated immune responses to a killed Salmonella enteritidis vaccine in a recent issue of Comparative Immunology Microbiology and Infectious...

Oral immunization with RfaH mutant protects mice against salmonellosis.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Oral immunization with an RfaH mutant elicits protection against salmonellosis in mice. According to recent research from Hungary and Germany, "Loss of the transcriptional antiterminator RfaH...

FDA accepts BLA filing for Vaccinia Immune Globulin.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Computer Sciences Corp. (CSC) announced the U.S. Food and Drug Administration (FDA) has accepted DynPort Vaccine Co.'s (DVC) filing of a biologics license application for Vaccinia Immune Globulin...

Early results show promise for strep vaccine.
September 1, 2004... 2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Preliminary results from a trial for a streptococcal vaccine indicate that the vaccine appears likely to offer protection against streptococcal infections, according to a new study. Efforts to...