Vaccine Weekly articles from October 2002

Vaccine Weekly archives from October 2002

Cholera toxin offers some protection against H. pylori infection.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Researchers in Sweden found that mmunization of mice with the cholera toxic (CT) did not protect against Helicobacter pylori infection, but did...

Murine aerosol challenge model provides correlation between antibody response and protection.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A group from the Dana Farber Cancer Institute and Harvard Medical School in Boston used the murine aerosol challenge model to demonstrate a...

Multiantigen vaccine effective against malaria in rhesus macaques.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Rhesus macaques were protected against a lethal Plasmodium knowlesi infection by immunization with a vaccine composed of cytokines and DNA plasmids...

Progress in pneumococcal vaccine development reported.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A need exists for inexpensive pneumococcal vaccines that cover a broad serotype range, according to a review in the Scandinavian Journal of...

Standard vaccine offers long-term immunity.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Scientists at the University of North Carolina at Chapel Hill have found evidence indicating that the standard vaccine against smallpox confers long-term immunity. Writing in the New England...

External researchers given access to CDC data.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- The U.S. Centers for Disease Control and Prevention's (CDC) National Immunization Program, and its managed care partners, have announced that researchers will be allowed access to data collected by the...

Mymetics registration statement effective.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Mymetics, Inc., (MYMX) announced that its registration statement on form S1 filed with the Securities and Exchange Commission has become effective, thereby registering the sale of up to 48,487,487...

DNA Vaccine vector induces IFN-alpha production in pigs.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- According to a study from Sweden, "The cytokine inducing capacity of the vaccine vector pcDNA3, a methylated form of the plasmid, and pcDNA3 encoding porcine interleukin (IL)-6 or granulocyte/macrophage...

Epidemiology of deadly mosquito-borne disease studied in Thai children.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Virologists with the U.S. military are studying the epidemiology of dengue viruses in young school children in Thailand. They recently reported initial findings in two articles in the American Journal...

Plasmid DNA on nanoparticles offers effective delivery of antigen.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Nanoparticles coated with plasmid DNA (pDNA) stimulated a stronger immune response in a murine model than did "naked" plasmid DNA, according to...

gag-based DNA vaccine effective in primates.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - An HIV DNA vaccine can produce sustained and effective cell-mediated immune responses to the virus in animals, researchers in the United States report. ...

Medical panel urges overhaul of military vaccine program.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Warning that "infectious agents remain a substantial threat to the operational capacity of U.S. military forces" and that "protecting the health of military personnel is essential to national security,"...

Program aims to reduce mortality by 50%.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Malaria, a tropical disease that has perplexed scientists and infects 300 million people per year, is one of the most complex health problems facing humanity. Since a past eradication attempt failed...

Additional patent issued for PADRE technology.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN), a biotechnology company focused on the development of pharmaceutical products using multiple, specific epitopes to activate the body's immune system, announced that the U.S....

Broad patent covers oncolytic virus therapies.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Cell Genesys, Inc., (CEGE) announced that it has been issued a broad patent (U.S. Patent No. 6,432,700) that includes specific composition of matter claims pertaining to the company's proprietary...

Key ruling issued on European vaccine microsphere patent.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- DOR BioPharma, Inc., announced that the company has been notified of a decision of the Technical Board of Appeal of the European Patent Office in the defense of European patent EP0 266 119 against an...

Political stability of developing countries rests on physical health.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Developing countries stand to profit most from advances in genome science, write Samuel Broder, Stephen Hoffman and Peter Hotez in the September 2002 issue of EMBO Reports. They claim that...

Vaccinia hyperimmune globulin contract awarded.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Cangene announces that it has been awarded a contract by the United States Centers for Disease Control and Prevention to develop and supply a vaccinia immune globulin (VIg) for use in treating and...

Eliminating neonatal disease in rural South African province studied.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- Modifying some cultural practices could have significant impact in reducing neonatal tetanus in the rural province of Mpumalanga, South Africa, according to a study from the Medical University of South...

Altered-peptide ligand has therapeutic activity.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- An altered-peptide ligand from an islet beta-cell-specific antigen in type 1 diabetes has been found to have therapeutic activity, report scientists at Neurocrine Bioscience Inc., California, USA. ...

Lactobacilli may have potential for commercial in vivo immunotherapy.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- A study in rats suggests lactobacilli could play a part in vaccine delivery. According to recent research from Sweden, "Lactobacilli have previously been used to deliver vaccine components for...

Prospects for edible vaccines limited, but still promising.(Brief Article)
October 2, 2002... 2002 OCT 2 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "The use of edible plants for the production and delivery of vaccine proteins could provide an economical alternative to fermentation systems. ...

DNA and hepatitis B virus vaccine evaluated in colorectal cancer patients.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The jury is still out on whether or not DNA vaccines are effective cancer fighters. "Despite an abundance of preclinical data, relatively little is known...

Schistosoma multivalent antigen reduces granuloma formation.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A multivalent and a single antigen from the adult Schistosoma mansoni worm demonstrated an ability to stimulate a protective immune response in vivo,...

Therapeutically effective dendritic cells generated by progenipoietin.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Progenipoietin (ProGP-4) stimulated the proliferation of dendritic cells that have shown effectiveness against cancerous tumors, according to a report...

Genetic vaccine can protect against Chagas disease.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A genetic vaccine against the parasite responsible for Chagas disease can protect animals from infection, researchers in the United States report. ...

Vaccination against the flu highly effective in the elderly.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Elderly adults, especially those with a high-risk medical condition, are significantly less likely to require hospitalization or to die if they are...

Wild-type measles strain responsible for SSPE outbreaks in New Guinea.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Genomic analysis revealed that outbreaks of subacute sclerosing panencephalitis (SSPE) in Papua, New Guinea, are caused by a wild-type measles virus,...

Groups at risk for severe reactions from vaccine.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Smallpox vaccines could do more harm than good for people with AIDS or allergic skin diseases, according to research presented in the September 2002 issue of the Journal of Allergy and Clinical...

Study vaccine ineffective against cypress pollen allergy.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- An attempt to develop a vaccine for cypress pollen allergy did not yield a sucessful immunotherapy, researchers in France report. "Cupressaceae pollen allergy is a world-wide pollenosis but...

'Naked DNA Company' expands management team.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Vical, Inc., (VICL) announced the expansion of its management team with the appointment of Alain P. Rolland, PharmD, PhD, as vice president, product development, and the appointment of Thomas G. Evans,...

Study emphasizes importance of genetic susceptibility to autoimmunity.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Genetic background, rheumatologists report, plays an important role in susceptibility to autoimmunity. "In previous studies we have established a link between cytomegalovirus (CMV) infection and an...

High-b-value q-space diffusion MRS enables early detection in rat model.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Results of a study by Tel Aviv University researchers suggest that that q-space analysis of high b-values diffusion MRS could be a new way to detect white-matter-associated disorders earlier. ...

Vaccination now required for elementary, secondary school enrollment.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- New Mexico and Mississippi join 38 states (plus the District of Columbia) that now require the chickenpox vaccine for day care, public school, or both. In addition, several states now have similar...

Synthetic gp41 analogs inhibit feline virus function.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in North Carolina have identified several synthetic molecules capable of suppressing the feline version of HIV (FIV). The conserved HIV...

Link to isoimmunization in ABO-incompatible, DAT-negative newborns unlikely.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Pediatric researchers caution that jaundice in certain newborns probably is not due to isoimmunization, as conventional wisdom has held. "It is stated that the direct antiglobulin (Coombs') test...

Immigrant children entering the United States may be receiving unnecessary vaccinations.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Refugee children arriving in the United States may be receiving immunizations unnecessarily, according to a report in the journal Clinical Infectious...

MedImmune responds to FluMist complete response letter.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- MedImmune, Inc., (MEDI) announced that it has completed the submission of information requested by the U.S. Food and Drug Administration (FDA) for FluMist (influenza virus vaccine live, intranasal), a...

NFID encourages Americans to follow CDC flu vaccination schedule.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- As influenza vaccination recommendations issued by the U.S. Centers for Disease Control and Prevention (CDC) go into effect, and the National Foundation for Infectious Diseases (NFID) has issued an...

Recent influenza A strains in Canada have evolved from two variants.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Infectious disease researchers in Canada are delving into the evolutionary history of influenza strains in that country. "Limited information is available concerning the molecular drift of the...

New assay called ideal for epidemiologic studies.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- According to a study from Kenya, "Epidemiologic studies of pneumococcal pneumonia, including vaccine efficacy trials, are hampered by a lack of sensitive and specific diagnostic tests. ...

Reasons for nonimmunization of children in north India identified.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Researchers have identified several factors contributing to lack of immunization in low income children in New Delhi, India. Of 500 children under age 5, "[o]nly 25% were found to have received...

FDA to consolidate review responsibilities for new pharmaceutical products.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Dr. Lester M. Crawford, deputy commissioner of the U.S. Food and Drug Administration (FDA), has announced the consolidation of FDA's responsibility for reviewing new pharmaceutical products into its...

Maternal vaccination could control RSV in at-risk children in Mozambique.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Researchers recommend that mothers of very young children at high risk of infection with respiratory syncytial virus should be vaccinated against the infectious pathogen. In a case-control study in...

New CEO outlines strategic plans for Flocor maker.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- CytRx Corp.'s (CYTR) new CEO, Steven A. Kriegsman, said he plans to shift the company's focus to licensing and strategic alliances for the development and marketing of its products. The company's...

Delivery schedule established with CDC for vaccinia hyperimmune globulin.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Further to the announcement of a 5-year supply and development agreement with the United States Centers for Disease Control and Prevention, Cangene announces that it has established a preliminary...

Early vaccine results encouraging.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- A British biotechnology company has reported "encouraging" results from an early-stage trial of its smallpox vaccine. Acambis PLC compared its ACAM1000 vaccine and the vaccine widely used during...

Some vaccines recommended.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- U.S. Department of Health and Human Services (HHS) officials are recommending that smallpox vaccinations be given to about 250,000-500,000 people, including hospital and emergency workers most likely to...

Study results indicate tb revaccination not warranted in japanese children.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- An assessment of the economics of revaccinating Japanese children for tuberculosis finds the practice is unnecessary. "Bacillus Calmette-Guerin (BCG) revaccination has been implemented in Japan...

Minimal change nephrotic syndrome associated with pneumococcal vaccine.(Brief Article)
October 9, 2002... 2002 OCT 9 - (NewsRx.com & NewsRx.net) -- Internists in Japan have reported the case of a woman who developed minimal change nephrotic syndrome shortly after receiving pneumococcal vaccination. "A 67-year-old female was admitted to our...

Vaccine reduces metastases after laparotomy.(pulmonary metastases)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Perioperative stimulation of the immune system with a vaccine consisting of lysed adenocarcinoma cells and an adjuvant reduced the number of...

Method of loading antigen onto dendritic cells affects immune response.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Directly fused dendritic cell-leukemia cell hybrids were the most effective promoters of antileukemia cytotoxic T lymphocyte (CTL) immune responses...

UT Southwestern researchers develop vaccine against ricin.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- UT Southwestern Medical Center at Dallas researchers have developed a vaccine in mice against the deadly toxin ricin. Ricin has been used as a biological weapon in many parts of the world. ...

Strategy for treating MUC1-expressing tumors depends upon tumor origin.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - MUC1-expressing tumors that originate in different organs require different effector cells and mechanistic tactics for elimination, according to a...

Fusion of pneumococcal surface adhesin and cytokine genes increases efficacy.(antipneumococcal vaccine)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have found a novel technique for improving the efficacy of an antipneumococcal vaccine. "Immunization of mice with...

Dead tumor cells improve melanoma vaccine immunogenicity.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A higher number of dead tumor cells in a vaccine containing autologous melanoma tumor cells increased the delayed-type hypersensitivity response in...

Mycobacterium bovis BCG inoculation may improve early response.(bacillus Calmette-Guerin)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A vaccine based on Mycobacterium bovis bacillus Calmette-Guerin (BCG) can improve the immune response to tuberculosis infection, researchers say. ...

Top researcher says vaccine could arrive in 5 years.(AIDS virus)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- After years of frustrating near-breakthroughs, a vaccine could be developed within 5 years that would provide complete protection against the AIDS virus, one of the world's leading AIDS researchers...

PrimaBioMed achieves clinical advancement and patent expansion in 2002.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- PrimaBioMed, Ltd., the cancer and immunotherapy research and therapeutic development company, reviewed fiscal 2002, its first full year as a public company. CEO Marcus Clark commented that 2002 was...

Pentrix vaccine trial advances to evaluation stage.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Australian Cancer Technology (AustCancer) (ACU) has announced that the phase 1b/2a clinical trial of the Pentrix anticancer vaccine, being undertaken at St Vincent's Hospital, Sydney, has advanced to...

Tumor cells overexpressing heat shock protein effectively inhibit murine colon cancer growth.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Growth of a murine CT26 colon carcinoma was completely inhibited by immunization of the mice with a vaccine containing a heat shock protein and cells...

Vaccine shortage prompts states to curtail immunizations.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Congressional auditors have found that more than half of America's immunization programs are rationing one or more childhood vaccines because of shortages, but government officials say supplies are...

Epidemiology of deadly mosquito-borne disease studied in Thai children.(dengue)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Virologists with the U.S. military are studying the epidemiology of dengue viruses in young school children in Thailand. They recently reported initial findings in two articles in the American Journal...

Stem cell researcher reports year-end 2002 net loss at $0.19.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Aastrom Biosciences, Inc., (ASTM) announced financial results for its fourth quarter and fiscal year ended June 30, 2002. The company reported that it completed the year with sufficient cash to...

Egg yolk a possible alternative to antibiotic treatment of ulcers.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Antibodies from the egg yolks of immunized chickens may be an effective alternative to antibiotic treatment of Helicobacter pylori infections, say Korean researchers in the September 2002 issue of the...

Dead tumor cells contribute to immunogenicity of vaccine.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Avax Technologies, Inc., (AVXT) announced the publication of a scientific paper on studies of its AC Vaccine technology for the treatment of cancer. The paper, by David Berd, Department of...

Novel design enhances GM-CSF tumor vaccine.(Granulocyte-macrophage colony-stimulating factor)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A cancer vaccine now undergoing clinical evaluation might be enhanced by simply changing the form in which it is presented. Granulocyte-macrophage...

New strain hits Africa.(meningitis)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- The emergence of a newly epidemic strain of meningitis in West Africa earlier this year has given renewed urgency to the search for a more effective and affordable vaccine. The World Health...

Microscience now able to deliver DNA vaccines orally.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Microscience - a British biotechnology company focused on the discovery and development of vaccines - has entered into an exclusive license agreement with the University System of Maryland (USM). ...

Life expectancy rose in the Americas, PAHO report shows.(Pan American Health Organization)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Life expectancy at birth rose by 6 years throughout the Americas between the early 1980s and the late 1990s, mostly because a reduced risk of dying from communicable and cardiovascular diseases,...

Bush vaccine plan begins with health workers, moves to general public.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Smallpox vaccine would be offered first to hospital emergency workers and slowly extended to other doctors, nurses, police and, eventually, the general public, under a Bush administration plan in the...

Emergency workers inoculated; Israelis buy more air filters, tranquilizers.
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- A Jerusalem hospital has begun inoculating emergency workers against smallpox in preparation for a possible attack by Iraq, officials said September 18, 2002, amid reports that sales of air filters,...

Scholars make a case for mass vaccination.(Brief Article)
October 16, 2002... 2002 OCT 16 - (NewsRx.com & NewsRx.net) -- Yale University researchers say mass vaccination in the event that the smallpox virus is released in the U.S. would result in many fewer deaths and eradicate more quickly any resulting epidemic than...

New method shortens dendritic cell preparation time.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A research team from the University of Antwerp in Belgium have developed a new and faster methods method of generating mature, viable, and highly...

Novel 12-month regimen protects youth after hepatitis B vaccination.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Just two doses of hepatitis B virus vaccine administered 12 months apart can protect adolescents from viral infection, according to a published report. ...

Cloned T9 cells protect against intracranial glioma tumors.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Immunity against intracranial T9 gliomas was conferred by treatment of rats with live cloned T9-C2 glioma cells that expressed macrophage...

Rates remain less than half for gay and bisexual men.(immunization for hepatitis A and B)
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- Though immunization rates for hepatitis A and B among men who have sex with men continue to improve, Gay and Lesbian Medical Association (GLMA) President Christopher E. Harris, MD, said that the...

Malaria-infected blood cells stimulate protective immune response.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Volunteers who received multiple vaccinations of a low dose of red blood cells infected with Plasmodium falciparum developed immunity against...

Cancer cells made to express CD154 prompt strong anticancer activity.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Tumor cells made to express CD154 can enhance anticancer activity via several avenues, researchers report. A growing interest in cancer vaccine technology...

Typhoid vaccine works through interferon-secreting CD8+ T cells.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The protective mechanism of the Ty21a attenuated live virus vaccine appears to occur through the action of CD8+ cytotoxic T cells that secrete...

Transgenic mouse model facilitates study of antistreptococcus vaccines.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- An animal model that produces human-like responses to a streptococcal superantigen has been developed. Researchers "used a transgenic murine model expressing human major histocompatibility complex...

Linking CD40L to self-tumor antigen enhances dendritic cell-based treatment.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- A study conducted in mice demonstrated that antitumor immune response of dendritic cell-based treatment is boosted by linkage of CD40-CD40 ligand to a self-tumor antigen. "CD40-CD40 ligand (CD40L)...

Monocyte-derived dendritic cells may be more user friendly.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- "Dendritic cells (DCs) play a critical role in initiating antigen-specific immune responses, because they are able to capture exogenous antigens for presentation to naive T cells on both MHC class I...

Phase III study of Viread shows favorable lipid, mitochondrial DNA profile.
October 23, 2002... 2002 OCT 23 - (NewsRx.com & NewsRx.net) -- by Lynn Yoffee, senior medical writer - Data from an ongoing phase III clinical trial suggest that Viread, Inc., (tenofovir disoproxil fumarate) has favorable effects on serum lipid profiles and...