Vaccine Weekly articles from November 2004

Vaccine Weekly archives from November 2004

Microneutralization assay using cytomegalovirus strains developed.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have developed an efficient fluorescence-based microneutralization assay using recombinant human cytomegalovirus strains expressing green fluorescent protein. "MedImmune Vaccines has...

MMR vaccination not associated with developmental disorders.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers have found no evidence that measles-mumps-rubella vaccination causes developmental disorders. Concern that measles-mumps-rubella (MMR) vaccination might cause autism has led to a fall...

Incidence of severe malaria useful as endpoint for vaccine trials.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers suggest that the incidence of severe Plasmodium falciparum malaria is a useful primary endpoint for vaccine efficacy trials. "Potential endpoints for blood stage malaria vaccine efficacy...

M. tuberculosis antigen structures confirm binding orientation.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity. According to a study from the United States and England, "The maintenance...

Interfering vaccine converts virulent infection into immunizing one.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- An interfering vaccine is a novel antiviral that converts a potentially virulent infection into one that is subclinical and immunizing. According to a study from England, "Infection with human...

HIV-1 immunogen vaccine plus antiretrovirals promotes virologic control.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Therapeutic immunization with an inactivated HIV-1 immunogen plus antiretrovirals promotes virologic control in asymptomatic HIV-infected subjects. According to a study from Spain, "To determine...

Study documents adverse events of pneumococcal vaccine in children.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Examination of reports from the first 2 years after licensure of a new vaccine against pneumococcal infections indicates that the majority of adverse effects are minor, but that continued surveillance...

Allergen immunotherapy reviewed.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers review allergen immunotherapy in a recent issue of American Family Physician. According to recent research from the United States, "Allergen immunotherapy (also called allergy vaccine...

Patient knowledge of allergy immunotherapy better than expected.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Patient knowledge of allergy immunotherapy was better than expected. "Immunotherapy is an invaluable therapy for allergic asthma, allergic rhinitis, and hymenoptera hypersensitivity. It is, however,...

Researchers begin evaluating efficacy of JuvImmune immunostimulant platform.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Juvaris BioTherapeutics, Inc., announced that researchers at the University of New Mexico have begun evaluating the efficacy of the JuvImmune immunostimulant platform against anthrax and small pox...

Glucuronoxylomannan exhibits anti-inflammatory effects in arthritis.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Glucuronoxylomannan exhibits anti-inflammatory effects in collagen-induced arthritis. "This investigation was planned to assess the therapeutic efficacy of glucuronoxylomannan (GXM) in...

Bioassay detects soluble MAdCAM-1 in body fluids.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers have developed a bioassay to detect soluble MAdCAM-1 in body fluids. According to recent research from New Zealand, "Mucosal addressin cell adhesion molecule (MAdCAM-1) is a key player...

Cholesteryl ester transfer protein induces long-lasting antibodies.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Subcutaneous and mucosal administration of a 26-amino acid cholesteryl ester transfer protein (CETP) epitope carried by heat shock protein 65 kDa in the absence of adjuvants induced long-lasting...

Antinuclear antibody absorption by hepatitis B vaccine warrants evaluation.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Antinuclear antibody absorption by hepatitis B vaccine warrants evaluation. According to published research from France, "the aim of this work is to propose a method to search for a possible...

Thyroid peroxidase DNA immunization replicates thyroid autoimmunity.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Thyroid peroxidase DNA is superior to protein immunization in replicating human thyroid autoimmunity in HLA-DRB1*0301 (DR3) transgenic mice. "Murine experimental autoimmune thyroiditis (EAT),...

Reassortant influenza vaccines control avian influenza.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have generated reassortant influenza vaccines by reverse genetics that allows utilization of a Differentiating Infected from Vaccinated Animals (DIVA) strategy for the control of avian...

Polycation-mediated precipitation captures plasmid DNA from alkaline lysate.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Polycation-mediated precipitation captures plasmid DNA from alkaline lysate. "The demand for highly purified plasmids in gene therapy and plasmid-based vaccines requires large-scale production of...

Interaction of two botulinum subdomains needed to elicit antibodies.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies. According to a study from France, "The botulinum...

Company changes name and prepares for HIV vaccine trial.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Research company Merix Bioscience announced the change of its name to Argos Therapeutics, Inc. Additionally, the company stated that it is preparing for an HIV clinical trial with Argos' proprietary...

Biotech company receives $3 million NCI award for anticancer vaccine protein.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Stellar Biotechnologies, Inc. has been awarded $3 million from the National Cancer Institute of the [U.S.] National Institutes of Health for the development of production methods, quality standards, and...

Chemotherapy after vaccination benefits glioblastoma patients.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Chemotherapy after vaccination was beneficial in glioblastoma multiforme patients. According to recent research published in the journal Clinical Cancer Research, "Although the development of...

Raf kinase expression increases mortality of influenza-infected mice.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Lung-specific expression of active Raf kinase results in increased mortality of influenza A virus-infected mice. According to published research from Germany, "Alterations in signaling via the...

Ascorbate-Cu(II) protects CF-1 mice against HSV-2 encephalitis.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Ascorbate-Cu(II) inactivated HSV-2 and protected CF-1 mice against encephalitis. "Ascorbate is an important antioxidant. However, in the presence of transition metals such as Cu(II) or Fe(III), it...

Polymerase inhibitor in encephalomyelitis linked to immunomodulation.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The therapeutic effects of PJ34 [N-(6-oxo-5,6dihydrophenanthridin-2-yl)-N,N-dimethylacetamide], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are...

ELISA to detect foot-and-mouth disease virus antibodies developed.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers have developed a biotinylated 3ABC recombinant protein in a solid-phase competitive ELISA for the detection of antibodies against foot-and-mouth disease virus. According to recent...

Ibis program granted three new government contracts for up to $10 million.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Isis Pharmaceuticals, Inc., (ISIS) announced that its Ibis program has been granted three new government contracts valued at up to $10 million for the continued development of its TIGER biosensor...

KiSS-1 downregulation causes tumor invasion/worse prognosis in gastric cancer.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- KiSS-1 downregulation causes tumor invasion and a worse prognosis in gastric cancer. According to recent research from Japan, "KiSS-1 is a promising candidate tumor-suppressor gene and may play a...

Monoclonal antibody identifies interstitial cells of Cajal in GI tract.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- A new monoclonal antibody (AIC) identifies interstitial cells of Cajal in the musculature of the mouse gastrointestinal (GI) tract. According to a study from Japan, "Interstitial cells of Cajal...

Host cell gene expression varies during HIV-1 latency or reactivation.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The host cell gene expression varies during HIV-1 latency or reactivation. "The existence of reservoirs of cells latently infected with human immunodeficiency virus (HIV) is a major obstacle to the...

CCR5-targeted SIV vaccination strategy prevents or inhibits SIV.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- CCR5-targeted SIV vaccination strategy prevented or inhibited SIV infection. "Cell-surface CCR5 is a major coreceptor with CD4 glycoprotein, mediating cellular entry of CCR5 strains of HIV-1 or SIV...

Health workers confirm Wisconsin's first flu case of the season.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The flu bug has arrived in Wisconsin, where health experts said they have confirmed the first case of the season. Laboratory tests found a Waupaca County woman had the state's first influenza case,...

Canadian biotech company begins two studies on cholesterol combination therapy.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Magistral Biotech (MBS) announced two new multi-center clinical studies that will study the effectiveness of Magistral's over-the-counter, cholesterol-lowering drug Libracol when taken concomitantly...

Heat shock protein is cytoprotective in gastric mucosa of cirrhosis.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Expression of a 72-kDa heat shock protein is cytoprotective in the gastric mucosa of cirrhotic rats. Portal hypertensive gastropathy (PHG) is a clinical entity that is observed frequently in...

Novel peptide-based vaccines generate immunity to hepatotropic pathogens.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Novel peptide-based vaccines generate immunity to hepatotropic pathogens. "Vaccines for the prophylactic and/or therapeutic immunization against hepatotropic pathogens (e.g., hepatitis B and...

Viral subunit protein plus CpG ODN protects against HSV-2.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Intravaginal immunization with viral subunit protein plus CpG oligodeoxynucleotides (ODN) induces protective immunity against herpes simplex virus 2 (HSV-2). According to a study from Canada,...

HPV type 18 L1 VLP vaccine safe and immunogenic in women.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Results from a phase I study indicated a human papillomavirus (HPV) type 18 L1 VLP vaccine was safe and immunogenic in women. "Human papillomavirus (HPV) infection can cause genital warts and...

Ethical principles for collective immunization programs outlined.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers outline ethical principles for collective immunization programs in the journal Vaccine. According to a study from the Netherlands, "Ethical issues arise in discussion of both the...

Medical, maternal, and child health care in Chinese women studied.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers have studied the needs of medical, maternal, and child health care in Chinese women students at the University of Tokyo. "According to the information provided by the University of...

CTL epitopes predicted using QM, SVM, and ANN techniques.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers can predict CTL epitopes using quantitative matrix (QM), support vector machine (SVM), and artificial neural network (ANN)techniques. "Cytotoxic T lymphocyte (CTL) epitopes are potential...

Energetic and nutritional regulation of immune response reviewed.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists review energetic and nutritional regulation of the adaptive immune response and trade-offs in ecological immunology in a recent issue of the American Journal of Human Biology. ...

Peptide-HSP70 complexes generate cytolytic T-lymphocyte responses.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Peptides complexed with the protein HSP70 generate efficient human cytolytic T-lymphocyte responses. According to recent research published in the journal Biochemical Society Transactions,...

Polysaccharides from Salvia officinalis are immuno-modulators.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Water-soluble polysaccharides from Salvia officinalis possess immunomodulatory activity. "A water-soluble polysaccharide complex (A) composed of galactose (17.9%), 3-O-methyl-galactose (3.0%),...

Bacterium causes U.S. flu vaccine shortage.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The reddish bacterium to blame for this year's shortage of flu vaccine has a colorful history. Until the 1960s, Serratia marcescens was considered harmless - so safe, in fact, that the military...

Disease management company to offer viral antidote to U.S. during flu season.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- GenoMed, Inc., (GMED) announced that it will offer its patent-pending broad spectrum viral antidote to the U.S. during the coming flu season this fall and winter. Because of difficulties that a...

Drug-DNA combination could offer longer-lasting, more efficient flu vaccine.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Research from Sweden suggests that adding the drug tucaresol to plasmid DNA influenza vaccines could offer longer-lasting and more efficient protection against the influenza virus. Annual flu...

Experts: Good hygiene can ward off flu.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The wisdom mothers have been dispensing for ages - wash your hands, eat your vegetables, go to bed earlier - turns out to be great advice for avoiding the flu. Doctors and nutritionists say careful...

Pediatricians: Flu vaccine needed to protect children under age 2.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- In a written statement submitted for a U.S. House of Representatives hearing, the American Academy of Pediatrics (AAP) reiterated the need for children ages 6-23 months to get vaccinated with the flu...

Study to test flu shot and nasal spray flu vaccine side by side.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- A University of Michigan (U-M) influenza expert is beginning a 3-year direct comparison of the effectiveness of flu shots vs. nasal spray flu vaccine. Flu shots have been around since World War II,...

Survey of hospitals quantifies flu vaccine price gouging.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The American Society of Health-System Pharmacists has conducted a survey of more than 2800 hospital pharmacy directors in the U.S. about how the flu vaccine shortage is affecting their ability to care...

Thirty million doses of influenza vaccine shipped to healthcare providers.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Aventis (AVE), part of the sanofi-aventis Group, announced that the company has shipped more than 30 million doses of its influenza vaccine, Fluzone, Influenza Virus Vaccine, for the upcoming season....

U.S. CDC urges high-risk groups to get vaccinated, healthy people to wait.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The loss of vaccine from Chiron Corp. has created a challenging situation for the United States vaccine supply going into this year's influenza season. The U.S. Centers for Disease Control and...

U.S. health services department releases statement regarding Chiron flu vaccine.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The following is a statement from the U.S. Department of Health and Human Services (HHS) regarding Chiron flu vaccine: "Clearly, the loss of the Chiron flu vaccine poses a serious challenge to our...

Cost of flu vaccine rising as supply dwindles.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Some drug distributors are taking advantage of the country's dwindling flu vaccine supply by raising prices for the medicine to up to 10 times its normal cost. Several distribution companies, which...

Effect of influenza vaccination on primary care contact rates studied.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Investigators have studied the effect of the vaccination of high-risk patients against influenza on primary care contact rates during epidemics. "A general practice (GP)-based retrospective cohort...

Health officials ask for corporate donations in Oklahoma.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Oklahoma Health Department officials want private companies to donate unused influenza vaccine so high risk groups can be immunized. The federal Centers for Disease Control and Prevention (CDC) and...

Hospital visit prevention by influenza vaccine during pregnancy studied.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Influenza vaccination during pregnancy did not appear to prevent hospitalization or outpatient visits for respiratory illness in pregnant women and their infants. "The Advisory Committee on...

Influenza Shot-Gouging: With scarce supplies of flu shots, prices go up, way up.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Jack Bond's hospital pharmacy needed 2,800 flu shots, but his supplier couldn't provide them. Plenty of other distributors were ready to meet his needs, though, for a price: as much as $600 for a vial...

Physician offers tips to avoid the flu in face of lack of vaccinations.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- In response to news of a flu vaccine shortage, public health officials urge younger, healthier individuals to forgo vaccines. The challenge now is to educate the public on other ways to avoid the flu,...

Remaining flu shots directed to high-risk patients.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The federal government moved to direct scarce remaining flu shots straight to pediatricians, nursing homes and other places that care for the patients who need them most. But only a fraction of the...

Study of influenza virus A M2 peptide conjugate vaccines conducted.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have conducted a preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys. "A universal influenza virus vaccine that does not require...

Vaccine failure underscores antiquated productions system.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The crisis in the flu vaccine supply in the United States has led to renewed calls to modernize a half-century-old manufacturing system that relies on millions of chicken eggs and a lot of educated...

With shortage of flu vaccine, bioterrorism drill becomes more real.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- The national shortage of flu vaccine has brought a bioterrorism drill planned for southeastern Colorado a lot closer to reality. Healthcare workers in 9 rural counties will go ahead with plans to...

Scientists meet to work on strategy to fight global viruses.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- More than 300 scientists from around the world shared information on tracking and curbing the cross-border spread of viruses as they met in India. "Emerging infections have taken center stage, not...

Healthy monkey can be kept by owner.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- A monkey that bit a utility worker has been returned to its owner after receiving a clean bill of health. Authorities removed the Capuchin monkey from Sue Kriz's home in Shueyville after it bit the...

Implantable chip provides medical information, privacy worries.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Medical milestone or privacy invasion? A tiny computer chip approved October 13, 2004, for implantation in a patient's arm can speed vital information about a patient's medical history to doctors and...

New malaria vaccine has promising test results.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have made important progress in the quest for a malaria vaccine, showing for the first time that childhood shots can prevent nearly one-third of cases and slash the risk of severe,...

Antibodies to P. vivax protein studied in malaria-exposed subjects.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the HLA class II and antibody responses to circumsporozoite protein repeats of P. vivax in individuals naturally exposed to malaria. According to recent research...

Molecular analysis of antibody response to malaria sporozoite reported.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists report the results of a molecular dissection of the human antibody response to the structural repeat epitope of Plasmodium falciparum sporozoite from a protected donor in a recent issue of...

Quantitative PCR used to test vaccines in human experimental malaria.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have performed a statistical analysis of malaria parasitemia measured by a quantitative real-time polymerase chain reaction. "Clinical trials are an essential step in evaluation of safety...

B-RAF is therapeutic target in melanoma.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- B-RAF is a therapeutic target in melanoma. According to a study from England, "B-RAF is a serine/threonine-specific protein kinase that is mutated in approximately 70% of human melanomas. However,...

Dendritic cell vaccine boosts T cell-mediated immunity to tyrosinase.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Vaccinia virus-transduced, CD34+-derived dendritic cell vaccination boosted T cell-mediated immunity to tyrosinase. Six American Joint Committee on Cancer stage IV melanoma patients were enrolled...

PorA-specific differences found in antibody avidity after Men B vaccine.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Investigators found PorA-specific differences in antibody avidity after vaccination with a hexavalent Men B outer membrane vesicle vaccine in children. According to recent research from the...

People often infected have poor immune response to Neisseria vaccine.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Frequently infected individuals exhibit aberrant IgG2 antibody response to Neisseria meningitidis polysaccharide A after vaccination. "In search for a possible explanation of the phenotypic...

Cancer research company receives grant to study cell-based cancer vaccine.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- MOLOGEN announced a grant from the Innovation Support Program of Berlin for the development of a cell-based, tumor-specific treatment for renal cell carcinoma. According to the announcement, MOLOGEN...

FDA grants fast-track designation for metastatic melanoma treatment.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Medarex (MEDX) announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for Medarex's fully human antibody against human CTLA-4, MDX-010 in combination with...

Sendai virus vaccine is safe and immunogenic in healthy adults.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Intranasal vaccination with murine parainfluenza virus type I (Sendai virus) was safe and immunogenic in healthy human adults. "Human parainfluenza virus-type 1 (hPIV-1) is the most common cause of...

Dr. Eric von Hofe named VP for product development and scientific affairs.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology Corp. (GNBT) announced that Dr. Eric von Hofe, PhD, an executive with the company's Antigen Express subsidiary, has been appointed as the company's vice president in charge of...

Computer simulations of strategies for pertussis vaccination developed.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have conducted computer simulations of five new strategies for adolescent and adult pertussis vaccination. According to a study from the United States, "Approximately one million adult...

Polio vaccines containing simian virus 40 may cause human cancer.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have found mixed evidence for a causal association between polio vaccines contaminated with simian virus 40 and cancer. According to published research from Canada, "In 1960, it was...

Change in polio vaccine policy eliminates cases of vaccine-associated polio.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- A change in the U.S. polio vaccination policy has led to the elimination of vaccine-associated paralytic poliomyelitis (VAPP), according to a new study. The last case of poliomyelitis (polio) in...

Vaccine-caused cases of polio have been eliminated in the United States.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- A switch in the type of polio vaccine recommended for use in the United States appears to have wiped out U.S. cases of the disease caused by the vaccine itself, the government says. In 2000, U.S....

Structural proteomics of the poxvirus family reviewed.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Researchers review the structural proteomics of the poxvirus family in a recent issue of Artificial Intelligence in Medicine. According to a study from the United States, "Recent concerns over the...

Saccharide-directed delivery to biological receptors optimized.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- Scientists have optimized saccharide-directed molecular delivery to biological receptors. According to published research from Spain, "Dendritic beta-cyclodextrin (betaCD) derivatives bearing...

HLA-DP4 presents immunodominant peptide from RSV G protein to T cells.
November 3, 2004... 2004 NOV 3 - (NewsRx.com & NewsRx.net) -- HLA-DP4 presents an immunodominant peptide from the respiratory syncytial virus (RSV) G protein to CD4 T cells. "CD4 T cells play a crucial role during virus infections by producing antiviral...