Vaccine Weekly articles from November 2003

Vaccine Weekly archives from November 2003

Heat shock protein from a non-autologous tumor used as anti-tumor vaccine.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Heat shock protein derived from a non-autologous tumor can be used as an anti-tumor vaccine. According to published research from Ireland, "Antigenic cross-reactivity between certain tumors has...

DNA vaccine coding for Kunjin virus RNA protects mice against West Nile virus.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- A DNA vaccine coding for the full-length infectious Kunjin virus RNA protected mice against the New York strain of West Nile virus. According to recent research published in the Proceedings of the...

Immunogene vaccine improves outcome after combination therapy for myeloma.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Immunogene vaccination improved the outcome after combination therapy for myeloma murine myeloma. According to a study from Canada, "Increasing evidence suggests a role for immunologic vaccination...

Virosome hepatitis A vaccine efficacious in young children in Nicaragua.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Results from a randomized placebo-controlled trial indicate that a virosome hepatitis A vaccine is efficacious in young children in Nicaragua. "Immunization of young children could control hepatitis...

Novel adjuvants promote immunity against blood-stage malaria in mice.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Novel immunostimulatory adjuvants promoted immunity against blood-stage malaria in mice. According to a study from Canada, "An important aspect of malaria vaccine development is the identification...

Voluntary smallpox vaccination program unlikely to provide optimal coverage.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- A voluntary smallpox vaccination program is unlikely to provide optimal coverage of the population. According to a study from Canada and the United States, "The recent threat of bioterrorism has...

Virus delivered nitroreductase/CB1954 acts synergistically with 5-FU on cancer.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- The enzyme-prodrug combination nitroreductase/CB1954 creates cancer cell apoptosis by the caspase pathway, and acts synergistically with 5-fluorouracil. According to published research from England,...

Passive immunotherapy appears to be an effective way to treat melanoma.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Passive immunotherapy should soon be a recognized way of effectively treating melanoma. According to recent research published in the journal Bulletin du Cancer, "The protocols of tumor...

Antigen-specific immunotherapy and cancer vaccines reviewed.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Scientists have published a review of antigen-specific immunotherapy and cancer vaccines in a recent issue of the International Journal of Cancer. "The specific activation of the immune system to...

Clinical studies of vaccines targeting breast cancer reviewed.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Investigators have published a review of clinical studies of vaccines targeting breast cancer in a recent issue of the journal Clinical Cancer Research. "Many clinical studies have been undertaken...

Dendritic cell vaccine induces T-cell immunity in stage IV melanoma patients.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma. According to a study from the United States, "There...

Her-2/neu is potential vaccine target for acute lymphoblastic leukemias.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- The Her-2/neu antigen is a potential vaccine target for acute lymphoblastic leukemias. "Her-2/neu is a tumor-associated antigen that is expressed on several adenocarcinomas and correlates with poor...

Promotion agreement signed with Baxter for vaccine manufacturing services.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Althea Technologies, Inc., a provider of gene-based manufacturing and testing services to accelerate drug development, announced that it has entered into an agreement with Baxter Healthcare Corporation...

Cancer vaccine company completes UKP 17M financing.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- BioVex, Ltd., announced the completion of a UKP 17 million (U.S. $28 million) private placement. The placement was led by Scottish Equity Partners (U.K.). Other new investors participating in the...

Vaccine maker files shelf registration statement for 15M shares.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Avant Immunotherapeutics, Inc., (AVAN) announced the filing of a shelf registration on Form S-3 with the U.S. Securities and Exchange Commission (SEC). Once declared effective by the SEC, the shelf...

Adjuvant licensed for the development of HIV vaccine.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR) and Hybridon, Inc., (HYBN) have entered into a license agreement for the use of Amplivax as an adjuvant in the development of a novel vaccine candidate for the...

Coverage varies widely for younger and older age groups.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Universal recommendations for influenza vaccination have been broadened to include adults aged 50-64 years in addition to those aged >65 years. Vaccination coverage is currently low. Influenza and...

Fed panel recommends flu shots for infants.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- A U.S. panel has recommended that children ages 6-23 months get a flu shot. Previously, such vaccinations were only encouraged. The recommendation by an advisory committee of the U.S. Centers for...

MedImmune expands intranasal-vaccine program.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- MedImmune, Inc., (MEDI) has induced a protective immune response against three of the most serious childhood respiratory viruses in a study incorporating intranasal-vaccine technology similar to that...

Genetic analysis of reassortants of strains of influenza B virus reported.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Scientists have published the results of a genetic and phenotypic analysis of reassortants of high growth and low growth strains of influenza B virus in a recent issue of the journal Vaccine. ...

A single VH domain intrabody to RAS stops transformation in vitro.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- A new way of generating intrabodies yields an intrabody to RAS that could inhibit related oncogenic transformation in vitro. According to recent research from England, "There is a major need in...

New cancer vaccine trial to begin.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- The first patient has been vaccinated in a New York University (NYU) Medical Center clinical trial of a new cancer vaccine. The vaccine is designed to prevent patients who have already had a kind...

Agency assigned to handle StaphVAX and WinRho SDF.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Integrity Healthcare Communications, the newest agency in the HealthSTAR Communications network, has been assigned several projects by Nabi Biopharmaceuticals (NABI). Nabi Biopharmaceuticals, which...

Liposomal meningococcal B vaccine enhances dendritic cell activation.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- A liposomal meningococcal B vaccine enhanced the activation of dendritic cells. "The effect of targeting strategies for improving the interaction of liposomal PorA with dendritic cells (DCs) on the...

Vaccine developer receives patent for delivery platform.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- BioVex Limited announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office in relation to one of its core patents. The patent relates to the use of herpes simplex...

Manufacturing agreement met for phase II cancer vaccine.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Prima Biomed Limited announced that its subsidiary Cancer Vac has entered into an agreement with Progen Industries Ltd (PGLAF) to commence the scale up manufacture for the therapeutic vaccine in its...

India winning polio fight, but final push still needed, says U.S. expert.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- India is close to eradicating polio but needs to make a final push, the head of the U.S. Centers for Disease Control and Prevention (CDC) said as she helped inoculate babies against the disease in New...

Poliovirus type 2 vaccine elicits strongest immune response in children.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- The poliovirus type 2 vaccine elicited a stronger immune response than did type 1 or 3 in Finnish children. "A total of 32 unimmunized children (median age 5 months) living in an orphanage in...

Researchers neutralize SARS virus in non-human tissue cultures.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- A team of scientists from the Massachusetts Biologic Laboratories (MBL) of the University of Massachusetts Medical School (UMMS) in Jamaica Plain and at the Medical School's Worcester campus, in...

Mutant toxic shock syndrome toxin 1 prevents Staphylococcus infection.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Vaccination with nontoxic mutant toxic shock syndrome toxin 1 protects against Staphylococcus aureus infection. "To investigate whether vaccination with nontoxic mutant toxic shock syndrome toxin 1...

Antismoking vaccine undergoes second clinical trial.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Xenova Group plc (XNVA) has initiated a second clinical trial for TA-NIC, its therapeutic vaccine that is under development for the treatment of nicotine addiction. This second phase I study builds...

Cholera toxin B subunit enhances systemic and mucosal antibody responses.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Intraperitoneal delivery of cholera toxin B subunit enhanced systemic and mucosal antibody responses. "Although cholera toxin (CT) is a potent mucosal adjuvant, its activity in systemic immunity is...

Tetanus toxoid and E. coli enterotoxin possess potent adjuvant activity.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Transcutaneous immunization with tetanus toxoid and mutants of Escherichia coli heat-labile enterotoxin as adjuvants elicit strong protective antibody responses. According to a study from France,...

Method to estimate effective vaccination rate developed.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Researchers have developed a method to estimate effective vaccination rate. "In some cases vaccination is unreliable. For example vaccination against pertussis has comparatively high level of...

Endogenous avian virus in chick-derived vaccines does not cause disease.
November 5, 2003... 2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Endogenous avian virus in chick-derived vaccines does not cause disease in vaccine recipients. According to published research from the United States, "Virions incorporating endogenous avian virus...

Group A streptococcal C5a peptidase is effective vaccine antigen.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Group A streptococcal C5a peptidase is an effective vaccine antigen. "The group A streptococcal C5a peptidase (SCPA) is a major surface virulence protein that facilitates the establishment of local...

Delivery of antigens onto bare skin may provide painless vaccination.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Delivery of antigens onto bare skin may provide painless vaccination. "The skin is an attractive route for delivery of vaccines because it is accessible and contains immunocompetent cells. This...

Vaccine candidate for Venezuelan equine encephalitis identified.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers have identified a vaccine candidate for Venezuelan equine encephalitis to begin testing in human trials. According to published research from the United States, "The central objective...

Mucosal delivery of HIV-1 Tat protein elicits strong immune response.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Mucosal delivery of the human immunodeficiency virus-1 Tat protein in mice elicits systemic neutralizing antibodies, cytotoxic T lymphocytes, and mucosal IgA According to a study from Italy, "Human...

Plasmodium vivax adapted to Aotus monkeys aids malaria vaccine development.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Discovery of a highly infective Plasmodium vivax strain adapted to Aotus monkeys will aid malaria vaccine development. According to a study from Colombia, "The New World primate Aotus nancymaae is...

Human T-cells recognize N-terminally Fmoc-modified peptide.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Human T-cells recognize N-terminally Fmoc-modified peptide. According to a study from Australia, "We aimed to generate T-cell clones specific for human pre-proinsulin. An HLA DQ8, CD4+ T-cell...

Quantitative functional brain mapping assesses progress of Alzheimer disease.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Quantitative functional brain mapping allows the assessment of the progress of Alzheimer disease. "Quantitative functional magnetic resonance imaging was applied to characterize brain function in...

Biopharm company to gain commercial rights to anthrax vaccine candidate.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- VaxGen, Inc., (VXGN) has entered into a license agreement with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) that gives VaxGen exclusive, worldwide rights to develop and...

NIH grant to fund development of DNA delivery of vaccines.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Robert G. Kramer, president of BioPort Corporation, announced that the manufacturer of the only U.S. Food and Drug Administration (FDA) approved anthrax vaccine will team with Therapeutic Systems...

Vaccine shows promise.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- After five major surgeries for a particularly aggressive form of breast cancer, Patricia Thomas called the little pinprick she received in a government study the simplest procedure she's undergone. ...

European research project focused on optimizing a cancer vaccine.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- IDM (Immuno-Designed Molecules), a biopharmaceutical company specializing in the field of cellular immunotherapy, announced that it will coordinate a European research project entitled "Dendritophages,...

Development efforts refocused on pathogen inactivation, vaccines.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Cerus Corporation (CERS) announced that the company is restructuring its operations to focus on its pathogen inactivation products for platelets and plasma and on its pipeline of therapeutics and...

Tick-borne encephalitis vaccine effective at half adult dose in children.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- The tick-borne encephalitis vaccine was effective at half the adult dose in children. According to recent research published in the journal Vaccine, "Two randomized, double blind dose comparison...

Company donates influenza vaccine to support CDC campaigns.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- In conjunction with the start of influenza vaccination efforts across the country, Henry Schein, Inc., (HSIC) is donating influenza vaccine to communities involved in two U.S. Centers for Disease...

Experimental vaccine elicits strong antibody response in primates.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- For the first time, scientists have demonstrated that an experimental vaccine for hantavirus pulmonary syndrome (HPS), a highly lethal disease, elicits a strong neutralizing antibody response in...

Hepatitis A vaccination effective at preventing disease.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Hepatitis A vaccination is effective at preventing disease "Inactivated hepatitis A vaccines have been available for more than a decade. Characteristics of the vaccines, comparative data among...

Vaccine cost-effective in preventing secondary hepatitis A infection.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Vaccination is cost-effective in preventing secondary hepatitis A infection. According to recent research from France, "Using a decision-tree based model, we investigated the cost-effectiveness of...

Hepatitis B vaccination less effective in healthy homosexual men.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Hepatitis B vaccination was less effective in healthy homosexual men than in a population of healthcare workers. "The aim of the study was to compare the responses of homosexual men (HM) receiving...

Stanley A. Plotkin honored by infectious diseases society.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- The Pediatric Infectious Diseases Society (PIDS) has established the Stanley A. Plotkin Lecture in Vaccinology to honor Dr. Plotkin, the Society's "Founding Father." The lecture, which will take...

Mucosal immune response occurs outside of Peyer patches.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- A mucosal immune response can occur outside of Peyer's patches. According to a study from England, "This article outlines the lymphoid structures and cell types important in the intestinal immune...

Phase III data for influenza vaccine presented at conference.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Data from five large studies with an investigational intranasal, cold-adapted trivalent influenza vaccine (CAIV-T) were presented at the Fifth International Options for the Control of Influenza...

Health Canada gives approval to begin field trial of FluINsure.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- ID Biomedical announced that it has received a "No Objection" letter from Health Canada conveying approval to begin its scheduled field study of FluINsure trivalent influenza vaccine, a nonliving...

Influenza and pneumococcal vaccines reduce mortality in elderly people.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- A 1-year follow-up demonstrated that influenza and 23-valent pneumococcal vaccines reduce hospital admissions and mortality in elderly adults. "To assess the effectiveness of influenza and...

Anti-anthrax antibody protects and treats anthrax infection in animal model.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Medarex, Inc., (MEDX) announced that its fully human antibody against anthrax, MDX-1303, protected against inhalation anthrax at a dose 10-fold lower than previously tested in rabbits treated with the...

Global leaders intensify commitment to prevent leading childhood killer.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- By 2005, almost half a million children will be saved every year if there are expanded efforts to immunize and protect all children against measles, international health experts say. At a landmark...

Capital investment to be used in part for cancer vaccine development.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Biovest International announced the completion of $5 million of capital investment under its April 10, 2003, investment agreement with Accentia, Inc., a Hopkins Capital Group portfolio company. ...

Study examines prevalence in Asian children.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Up to 60% of Asian children hospitalized for diarrhea are infected with rotavirus - double the previous estimate, according to a study. Rotavirus, which under the microscope has a wheel-like...

Biopharmaceutical company manufacturing SARS vaccine for research center.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Vical Incorporated (VICL) has been requested to manufacture clinical-grade supplies of an experimental DNA vaccine against the severe acute respiratory syndrome (SARS) virus for development planned by...

Orthopoxviruses detected using microarrays of immobilized oligonucleotides.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers report the detection and discrimination of orthopoxviruses using microarrays of immobilized oligonucleotides. "Variola virus (VARV), causing smallpox, is a potential biological weapon....

BSYX-L210 meets endpoints of safety and microbiological activity.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Biosynexus, Inc., a privately held biotechnology-pharmaceutical company, announced completion of the phase I/II study of its topical anti-staphylococcal cream, BSYX-L210, for the eradication of...

Mouse monoclonal antibodies for pneumolysin characterized.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers have characterized mouse monoclonal antibodies for pneumolysin. "Pneumolysin (PLY) is a cholesterol-dependent cytolysin (CDC) produced by Streptococcus pneumoniae, the main cause of...

Lentinan stimulates host defense against tuberculosis infection.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Given prior to infection, Lentinan stimulates host defense against M. tuberculosis in mice. According to recent research from Bulgaria, the "protective effects of Lentinan (Ajinomoto, Japan)...

Natural autoantibodies can predict the outcome of immune response.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers suggest that natural autoantibodies can function as tools to predict the outcome of immune response in a recent issue of the Scandinavian Journal of Immunology. According to a study...

Recent advances in automated solid-phase carbohydrate synthesis reviewed.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers review recent advances in automated solid-phase carbohydrate synthesis in a recent issue of Current Opinion in Drug Discovery and Development. "The past year has witnessed significant...

Simultaneous measurement of pneumococcal polysaccharide antibodies reported.
November 12, 2003... 2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers have developed a method for simultaneous measurement of antibodies to 23 pneumococcal capsular polysaccharides. According to published research from the United States, "We describe a...

Dendritic cell vaccine generates anti-B16BL6 melanoma immunity in mice.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Dendritic cells transduced with gp100 gene by RGD fiber-mutant adenovirus vectors are highly efficacious in generating anti-B16BL6 melanoma immunity in mice. "Dendritic cells (DCs) are the most...

Transgenic plants express human papillomavirus type 16 major capsid protein.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Scientists have developed transgenic plants that express human papillomavirus type 16 major capsid protein. According to published research from South Africa, "The production of vaccine antigens...

Individualized human scFv vaccines produced in plants.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Scientists have produced individualized human scFv vaccines in plants. "We have developed a method for rapidly producing in plants the idiotype regions of the tumor-specific Ig as single-chain Fv...

Antibodies to Plasmodium falciparum merozoite protein protective.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Serum IgG3 antibodies against the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malaria. "The merozoite surface protein 2 (MSP2) of...

Oral delivery of Norwalk virus-like particles elicits IgA antibodies.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Oral vaccination with Norwalk virus-like particles elicited the production of IgA antibodies in volunteers. According to published research from the United States, "Norwalk virus-like particles...

Bacterial protein produced in starch granules of transgenic maize kernels.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Bacterial proteins were produced in starch granules of transgenic maize kernels. "The B subunit of Escherichia coli heat labile enterotoxin (LT-B) is a potent oral immunogen with potential for use...

NIH-funded HIV vaccine design and development team in place.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- The U.S. National Institutes of Health (NIH) has awarded a $19 million, 5-year grant for HIV vaccine development grant to Novavax, Inc., along with partners at Emory University School of Medicine and...

New $16.8M NIH award supports development of vaccine.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- AlphaVax, Inc., announced that it has received notice of a new 5-year, $16.8 million contract from the National Institute of Allergy and Infectious Disease (NIAID) of the National Institutes of Health...

Anthrax vaccine confers protection against both bacilli and toxins.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- A dually active anthrax vaccine conferred protection against both bacilli and toxins. According to a study from the United States, "Systemic anthrax is caused by unimpeded bacillar replication and...

Positive phase II results reported on cholesterol management vaccine.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Avant Immunotherapeutics, Inc., (AVAN) announced positive preliminary results from a placebo-controlled phase II clinical study of its experimental cholesterol management vaccine, CETi-1. Results...

Two companies collaborating on breast cancer vaccine.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Bavarian Nordic and Pharmexa have entered into a collaborative agreement that will test the use of Bavarian Nordic's proprietary MVA-BN vector technology in combination with Pharmexa's HER-2 DNA...

Immunotherapy and antiangiogenic therapy combine to reject tumors.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Immunotherapy and antiangiogenic therapy combine to reject tumors. According to recent research from the United States, "immunotherapy is an attractive strategy for cancer treatment. However,...

Clinical application of dendritic cells in cancer vaccines reviewed.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- Researchers have reviewed the clinical application of dendritic cells in cancer vaccination therapy in a recent issue of the journal APMIS. According to scientists in Denmark, "During the last...

GMCSF gene modified tumor vaccine shows promise in advanced lung cancer.
November 19, 2003... 2003 NOV 19 - (NewsRx.com & NewsRx.net) -- A GMCSF gene modified tumor vaccine has shown promise for the treatment of advanced stage non-small cell lung cancer. According to a study from the United States, "Treatment for advanced stage...