Vaccine Weekly articles from November 2000

Vaccine Weekly archives from November 2000

Dendritic Cells Useful for Presenting Antigen.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Dendritic cells (DCs) expressing tumor antigens are promising anti-cancer vaccines, researchers in the United States reported. "An important shortcoming in current viral and tumor cell vaccines has been...

Combination Vaccine and Radiotherapy Kills Tumors in Mice.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Researchers in Hungary found that cytokine-expressing autologous cancer cell vaccines combined with radiotherapy effected cures in a majority of mice with brain tumors. "The combined therapeutic effect of...

In vivo Electroporation Enhances Immunization Efficiency.(DNA vaccine research)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- In vivo electroporation enhances the transfection efficiency of DNA vaccines, researchers in the United States reported. "Naked DNA injection with electropermeabilization (EP) is a promising method for...

Protective T-Cell Responses Induced by DNA Immunization.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- DNA vaccination provides immune responses as protective as live virus infection, a new study shows. "CD8(+) T-cell responses can be induced by DNA immunization, but little is known about the kinetics of...

HIV-1 Plasmid Antigens and IL-12-Expressing Plasmids Key Components.(interleukin-12)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- In a recent study, researchers in the United States observed transient declines in viral load in HIV-1 infected chimpanzees vaccinated with HIV-1 DNA vaccines. J.D. Boyer and colleagues, University of...

Recombinant gp160 Stimulates Immune Responses in Adults With Advanced Infection.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- A recombinant HIV-1 gp160 vaccine was well tolerated and stimulated immune responses in adults with advanced HIV infection, health officials in Massachusetts reported. In a study of the "immunogenicity of...

Recombinant Vaccinia Virus Induces HPV-Caused Tumor Regression.(human papillomavirus)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Researchers in Mexico evaluated a recombinant vaccinia virus containing the papilloma E2 protein for its ability to eradicate papilloma-based tumors. "Human papillomavirus infection is associated with...

Longer Needles Reduce Local Reactions in Babies.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Using longer needles to immunize infants causes less redness, swelling, and tenderness, a new study shows. The study calls for vaccine manufacturers to review their policy of supplying a shorter needle in...

Is the Flu Vaccine Still Needed?(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Yes, the flu vaccine deliveries are late this year. And yes, in most years the vaccine isn't cost-effective for working adults. But the vaccine still has positive health effects and should be administered...

Vaccines Cost-Effective for Healthy Adults.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Results from a simulation model confirmed that vaccination of healthy adults against influenza is cost-effective prophylaxis. "Influenza is a major public health problem associated with up to 40,000 excess...

Adjuvants Are Important Ingredient.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Researchers suggest that a multiple antigenic peptide (MAP) is an effective and non-toxic adjuvant for mucosally-delivered vaccines. "Intranasal delivery of vaccines benefits in the induction of local...

Indirect Effect Realized By Hib Vaccination of an American Indian Population.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Community-wide benefits were realized in an American Indian population where the children received Haemophilus influenzae type b (Hib) vaccination. "Oropharyngeal carriage studies of Hib and the rapid drop...

Results in Mice Suggest Peptide Vaccination Could Offer New Hope.(for treatment of systemic lupus erythematosus)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Peptide-specific vaccination has prolonged survival in a murine model of systemic lupus erythematosus (SLE). "Studies in humans and mice with SLE suggest that the development of autoantibodies and disease...

Study Evaluates Risk of Acute Flaccid Paralyses in Brazil.(oral poliovirus vaccine side effects may cause risk of acute flaccid paralyses)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Oral poliovirus vaccine (OPV) has been related to acute flaccid paralyses in Brazil. "At the present time, in Brazil and other countries in the Americas, the only cases of paralytic poliomyelitis due to...

U.S. Defense Department Says Vaccinations Safe.(anthrax vaccine)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- A top U.S. Department of Defense expert on chemical and biological warfare says the pleas of service members claiming harm from the anthrax vaccine fail to prove the shots are either unsafe or ineffective. ...

Clinical Update on Vaccine Presented.(Northwest Biotherapeutics Inc.)(prostate cancer vaccine)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Northwest Biotherapeutics, Inc., announced that it presented a clinical update for its prostate cancer vaccine at the October 2-4, 2000, Cancer Vaccines 2000 Conference in New York City. Michael L....

Volunteers Sought for Trial of New Combination Chickenpox Vaccine.(combining chickenpox vaccine with measles, mumps, rubella vaccine)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- There are 240,000 cases, 1,200 hospitalizations, and 4.2 deaths each year from chickenpox in Australia. By the age of 12 years, over 60% of children will have had chickenpox (varicella zoster virus), a...

Abciximab Causes Complications in Cardiac Surgery.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Abciximab-treated patients have a higher occurrence of bleeding complications during cardiac surgery, noted researchers in the United States. "Early surgical experience with abciximab and other...

Avant Awarded Grant for Vaccine Development.(Avant Immunotherapeutics Inc.)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Avant Immunotherapeutics, Inc. (AVAN) announced it has been awarded a Phase I Small Business Innovation Research (SBIR) grant to support the development of a vaccine for genital herpes. The grant was...

European Commission, WHO, and UNAIDS Take United Stand Against Killer Diseases.(HIV/AIDS, malaria, and tuberculosis)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- The European Commission, the World Health Organization, and the Joint United Nations Program on HIV/AIDS announced a common stand against the epidemics of HIV/AIDS, malaria, and tuberculosis in the developing...

Engineered Red Blood Cells Act as Decoys for HIV.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Genetically engineering red blood cells to express the CD4 receptor may be a way to "fool" HIV in vivo, researchers in Australia suggest. "Early stages of HIV infection are associated with an acute phase...

FDA Says Latest Whooping Cough Vaccine Proving Safer.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- A newer whooping cough vaccine intended to reduce side effects is safer for babies than previous versions, according to a U.S. Food and Drug Administration (FDA) study. The findings are good news for...

Alloimmunization with Paternal Mononuclear Cells is Successful.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Alloimmunization with paternal mononuclear cells can be used to successfully treat recurrent spontaneous abortion (RSA), finds a study from Argentina. "Alloimmunization as a treatment for RSA is still...

Immuno-Gene Therapy Results Promising in Murine Model.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- Transduction of renal cell carcinoma cells with cytokine genes resulted in reduced tumor growth and increased survival in murine models, researchers in Poland reported. "Renal cell cancer is resistant to...

Novel Adjuvant Boosts Hepatitis B Vaccine Response in Adolescents.(HBsAg/SBAS4 compared to EngerixB)(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- New evidence points to the ability of a novel adjuvant called SBAS4 to increase the effectiveness of the hepatitis B virus (HBV) vaccine in adolescents. In fact, this novel adjuvant-containing vaccine only...

CDC Researchers See No Association Between Hep B and Hib Vaccines and Diabetes.(Brief Article)
November 1, 2000... 2000 NOV 1 - (NewsRx.com) -- United States government researchers at the Centers for Disease Control and Prevention in Atlanta, Georgia, can find no evidence that hepatitis B virus (HBV) vaccine and the Haemophilus influenzae type b (Hib)...

Trial Shows Infants Not Protected by SPf66 Vaccine.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) Infants do not respond as well as older children to vaccination with the SPf66 peptide vaccine, study results show. "The development of a malaria vaccine is a priority for improved and sustained malaria...

Non-Replicating Live Vaccine Protects Macaques from Challenge.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Oral immunization with a non-replicating live HIV vaccine protected monkeys from vaginal challenge with a pathogenic virus. "Development of a safe, non-replicating vaccine is the ultimate goal of the HIV...

Synthetic Long Peptide Elicits Protection Against Parasite.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- A synthetic long peptide derived from the Plasmodium berghei circumsporozoite protein is immunogenic in a vaccine formulation. "We compared the immunogenicity of two preparations of a peptide derived from...

HIV Neutralizing Antibody Binds to HIV-1 Envelope Peptide.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Certain peptides may help in the design of anti-HIV immunogens, according to researchers in the United States. "The human monoclonal antibody 2F5 (MAb 2F5) binds to a linear B-cell peptide epitope from the...

Dendritic Cells Mediate Protective Antiviral and Antitumor Immunity.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- According to a study from Switzerland, activation of dendritic cells (DC) by a liposomal peptide vaccine induced antiviral and antitumor protection in vivo. "Initiation of antiviral and antitumor T-cell...

Britain Orders Polio Vaccine Recall Because of Mad Cow Disease Fear.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Britain's Medicines Control Agency ordered the recall of a brand of polio vaccine on October 20, 2000, after determining the manufacturer had breached safety measures that prevent transmission of bovine...

Corporate Alliance Expanded.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Therion Biologics Corp., Cambridge, Massachusetts, and Aventis Pasteur Limited, Toronto, Ontario, Canada, have agreed to expand the length and scope of their existing collaboration for development of cancer...

Vaccine One Year From First Efficacy Analysis.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- VaxGen (VXGN), Brisbane, California, announced that it is now one year away from its first opportunity to determine if its preventive HIV/AIDS vaccine is effective. The milestone was reached when VaxGen's...

T Cells Hold Clues to Better Vaccines, Infectious Disease Treatment.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- How T cells learn to fight off infections and other invaders is the focus of researchers at the Medical College of Georgia in Augusta. They hope better information about how these front-line defenders do...

Patch Technology Awaits FDA Approval for Clinical Trials.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- In five to 10 years, flu vaccinations could be as simple as applying an adhesive patch. University of Alabama, Birmingham, researcher De-chu Tang, PhD, is awaiting U.S. Food and Drug Administration...

Broad Patent Received for Plant-Based Edible Formulations.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- ProdiGene, College Station, Texas, announced receipt of a patent for a process that uses plants to develop oral vaccines that can immunize humans and animals against viral diseases. ProdiGene's patented...

Encouraging Results from MUC1/IL-2 Immunotherapy Clinical Trial Reported.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) Results from a clinical trial of MUC1 and interleukin (IL)-2 immunotherapy in breast cancer patients are encouraging. "Polymorphic epithelial mucin, encoded by the MUC1 gene, is present at the apical surface...

Phase II Clinical Trial for Vaccine Announced.(Epstein-Barr virus vaccine)
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Aviron (AVIR), Mountain View, California, announced the initiation of a Phase II clinical trial of an investigational vaccine against Epstein-Barr virus (EBV) being developed under its license with SmithKline...

DNA Vaccine Controls AIDS in Monkeys.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- A DNA vaccine, combined with an extra immune protein, delivers a one-two punch that appears to control a highly pathogenic AIDS virus and prevent the development of the disease in monkeys, a team of researchers...

HIV-1 Antigen and Immunostimulatory Sequence Stimulate Antibody Responses.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) Researchers in the United States report that they may have developed the ideal candidate HIV-1 vaccine for testing in both primates and humans. "We hypothesized that HIV-1 specific CD4(+) T helper immune...

Hepatitis A and B Vaccinations Rates Improve But Majority of Gay, Bi Men Still Not Protected.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- A survey conducted for the Gay and Lesbian Medical Association (GLMA) suggests that vaccination rates for hepatitis A and B in the U.S. have increased significantly in large urban areas, but that a majority of...

Priority Influenza and Pneumococcal Vaccination Urged for High-Risk Groups.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- U.S. Surgeon General David Satcher, MD, PhD, and representatives of leading medical groups are urging priority vaccination of individuals in the U.S. who are at high risk for serious complications from...

Singapore to Start Hepatitis B Vaccination Program.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Singapore plans to start testing students in secondary schools, colleges, universities, and technical schools for hepatitis B. Parliamentary secretary for health Chan Soo Sen said on October 21, 2000, that...

Gamma-Glutamyl-Containing Peptides Have Potential.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Gamma-glutamyl-containing peptides have immunomodulatory potential, researchers in the United States and Russia reported. "Earlier we described gamma-glutamyl and beta-aspartyl containing peptides that...

High-Risk Patients Need First Flu Shots.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- Dr. Raymond Scalettar is angry. He has to send elderly lung-disease patients to nearby supermarkets for a flu shot. Why? Some huge grocery chains received thousands of vaccine doses before manufacturers...

Major Vaccine Research Contract Awarded.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- In its continuing efforts to promote research on vaccines to prevent malaria, the U.S. National Institute of Allergy and Infectious Diseases (NIAID) recently awarded a seven-year, $43.8 million contract to...

Live Vaccines, Poor Surveillance Threaten Eradication in Western Pacific Region.
November 8, 2000... 2000 NOV 8 - (NewsRx.com) -- The eradication of poliomyelitis from the western pacific region was due to be declared on October 29, 2000. However, two studies in the October 28, 2000, issue of The Lancet highlight the remaining hurdles...

Novel Lipopolysaccharide Vaccine Immunogenic in Rabbit Model.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Preclinical data of a novel liposomal complete-core lipopolysaccharide (LPS) vaccine against numerous bacterial pathogens are encouraging. "Low preoperative anti-endotoxin antibody levels have been shown...

B7 Co-Stimulatory Requirements Differ According to Vaccine Type.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Requirements for B7 co-stimulation differ according to whether the vaccine is a DNA vaccine, a protein vaccine, or a recombinant poxvirus vaccine, a recent study indicates. "Whether B7-1 and B7-2 have...

Phase I Trial of a Peptide Vaccine Encourages Further Evaluation.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Researchers in the United States have evaluated a peptide vaccine against human papillomavirus (HPV) in women with high-grade cervical and vulvar intraepithelial neoplasia who were HPV-16-positive. ...

Survey: Vaccines Confuse Parents.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- A sizable number of parents have misconceptions about vaccines, with many believing that too many immunizations can weaken their children's ability to fight diseases, a survey found. About one-fourth of...

Neurological Complications from MMR Immunization are Rare.(measles, mumps, and rubella vaccine)
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Although rare, neurological complications from the measles, mumps, and rubella (MMR) vaccine have been reported. "The incidence of neurological sequelae of measles, mumps, and rubella has decreased...

Collaboration Announced to Develop Vaccine.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Galenica Pharmaceuticals, Frederick, Maryland, announced that it has entered into an agreement with the Naval Medical Research Center (NMRC) Malaria Program of the U.S. Navy to evaluate Galenica's proprietary...

Vaccine Elicits Protective Immune Response in Monkeys.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Genzyme Transgenics Corp. (GTC) (GZTC), Framingham, Massachusetts, announced that a malaria vaccine protein under development using GTC's technology has elicited protection against malaria in primates. ...

Phase III Clinical Trial Data Indicate Vaccine Benefits Patients with Specific HLA Types.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Corixa Corporation (CRXA), a research and development-based biotechnology company, announced that additional data from its Phase III, randomized trial to evaluate Corixa's therapeutic vaccine Melacine(R), for...

Clinical Trial Tests Vaccine to Treat Human Papillomavirus-Induced Tumors.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Schering AG (SHR), Berlin, Germany, and MediGene AG (MDG), Munich, Germany, have announced the start of a multicenter Phase I/II clinical trial for MediGene's HPV16L1E7CVLP Vaccine to treat pre-cancerous...

DNA Vaccine Stimulates Neutralizing Antibodies in Murine Model.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Genetic immunization with a DNA vaccine coding for Epstein-Barr virus (EBV) produced neutralizing antibodies in a murine model, researchers from the United Kingdom and the United States reported. "The...

Immunization Would be Economically Beneficial in Argentine Children.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Routine vaccination of children in Argentina against hepatitis A virus (HAV) would be economically beneficial, researchers from that country announced. "HAV remains one of the most frequently reported...

DNA Vaccine Stimulates Unique Immunogenicity.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- A hepatitis B virus (HBV) DNA vaccine stimulates immunomodulatory responses and may have therapeutic benefit, researchers in Hong Kong report. "HBsAg [hepatitis B surface antigen] encoded in...

Peptide Technology Boosts Immune Response in Mice.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- The Naval Medical Research Center (NMRC) and Cel-Sci Corp. (CVM) announced that an experimental peptide, based on Cel-Sci's LEAPS (Ligand Epitope Antigen Presentation System) technology, induced protective...

University Answers FDA Deficiency Findings.(University of Oklahoma)
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- The University of Oklahoma is preparing answers to each of almost 60 potential deficiency findings by the U.S. Food and Drug Administration (FDA) involving tests of an experimental drug for skin cancer. ...

Liposomal Vaccine is Immunotherapeutic at Higher Dose.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- A liposomal vaccine targeting the MUC1 peptide stimulated immune responses in non-small cell lung cancer (NSCLC) patients enrolled in a Phase I study. "A liposomal formulation of a 25-amino acid MUC1...

Human Monoclonal Antibodies Produced in Murine Model are Protective.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Researchers in the United States have produced human monoclonal antibodies (MAbs) against Pseudomonas aeruginosa (PA) from a transgenic mouse model. The MAbs may be useful as a therapeutic agent against...

Typhoid Vaccination Recommended for Short-Term Travel.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Vaccination for typhoid fever should be considered for even short-term visits to high-risk areas, according to a report presented at the American Society for Tropical Medicine and Hygiene. Dr. Ellen...

Children in South Africa are Receiving New Intradermal BCG Vaccine.
November 15, 2000... 2000 NOV 15 - (NewsRx.com) -- Children in the Northern Province of South Africa are being immunized against tuberculosis with a new intradermal bacillus Calmette-Guerin vaccine. The Province's health department recently introduced the...

Vaccine Candidates Identified from cDNA Expression Library.(visceral leishmaniasis)
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Researchers in the United States have identified vaccine candidates for visceral leishmaniasis by immunizing mice with sequential fractions of a cDNA expression library. "Visceral leishmaniasis caused by...

GM2-KLH/QS-21 Vaccine Induces Anti-GM2 Antibodies.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- New study findings indicate that GM2/KLH/QS-21 (GMK) vaccine is effective at inducing anti-melanoma antibodies in patients undergoing concurrent interferon therapy. "We have studied the serum from 52...

Varicella Vaccine Protects Adults from Serious Disease.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Live attenuated varicella vaccine (LAVV) of healthy adults protects them from serious illness, researchers report. "Immunization of susceptible adults with varicella vaccine is recommended, but the...

Transmission-Blocking Vaccine Should Target Specific Region of Antigen.(malaria vaccine)
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Future transmission-blocking antimalarial vaccines may target a region of Plasmodium falciparum antigen Pfs25, which produces highly potent transmission-blocking antibodies, suggested government researchers...

Idiotype-Derived Mimotope May Be Useful for Vaccine Development.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- An idiotype-derived mimotope from Streptococcus pneumoniae may be useful for the development of a T-cell-dependent vaccine against infection by this bacterium. "Even in the age of antibiotics,...

Data for CAP Vaccine Adjuvant Announced.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- BioSante Pharmaceuticals, Inc. (BTPH; CDNX-BAI), Lincolnshire, Illinois, announced that data pertaining to its CAP vaccine adjuvant have been published in the November 2000 issue of Clinical and Diagnostic...

European Committee Issues Positive Opinion on Vaccine.(Prevenar receives positive feedback)
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- American Home Products Corp. (AHP), Madison, New Jersey, announced that the Committee for Proprietary Medicinal Products (CPMP), the scientific advisory panel for the European Medicines Evaluation Agency...

U.N. Wraps Up Campaign in Disputed Sudanese Region.(polio eradication campaign)
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- The United Nations said on November 7, 2000, that it vaccinated more than 66,000 children against polio in southern Sudan's disputed Nuba Mountains during October, only the second time it has gained access to...

Patent Awarded on New Delivery Platform.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Avax Technologies, Inc. (AVXT), Kansas City, Missouri, announced that it has been granted U.S. Patent No. 6,140,114 from the U.S. Patent and Trademark Office entitled, "Defective viral vaccine particles...

Two Major Allergens Identified in Timothy Grass Pollen.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- According to a study from Germany, pollen of timothy grass (Phleum pratense) has two major allergens that affect people. "More than 70% of the patients allergic to grass pollen exhibit immunoglobulin E...

Murine Studies Suggest Antibiotic Helps Reduce Plaques, Vaccine Improves Learning.(clioquinoline)
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- A researcher says that an antibiotic tested on mice genetically designed to mimic the effects of Alzheimer's disease reduced and even eliminated protein deposits that are a major feature of the disease. ...

Cancer Vaccine Stimulates Tumor-Specific Immune Responses.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Clinical trial data show that vaccination of patients with recurrent malignant astrocytoma with autologous tumor cells and granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulate immune responses,...

Combination Chemo/Immunotherapy Evaluated in Metastatic Disease.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Pilot trial data from a combined modality high-dose chemotherapy regimen with stem cell transplantation and adoptive immunotherapy for breast cancer are encouraging. "We have previously demonstrated that...

Distributor Price Gouging of Influenza Vaccine Condemned.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- The following statement was issued by Richard F. Corlin, MD, president-elect of the American Medical Association: [helv] The American Medical Association (AMA) has received numerous reports from...

WHO Center Investigates Two-Dose Schedule for Combination Vaccine in Children.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Researchers at the World Health Organization's Collaborating Center for Prevention and Control of Viral Hepatitis, located at the University of Antwerp in Belgium, propose that a combination hepatitis A and B...

Basiliximab Immunosuppression Beneficial to Children.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- The use of basiliximab (BX) combined with low-dose calcineurin inhibitors reduces nephrotoxicity complications in children after liver transplantation, researchers in the United Kingdom reported. "Liver...

Incidence Declined in U.S. in 1999.(measles cases decline)
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- Reported cases of the measles in the Americas and Caribbean countries dropped steeply last year, U.S. government researchers said on November 2, 2000. The U.S. Centers for Disease Control and Prevention...

Throat Swabbing Underestimates Infection.
November 22, 2000... 2000 NOV 22 - (NewsRx.com) -- A research letter published in the November 11, 2000, issue of The Lancet suggests that the technique of throat swabbing to detect Neisseria meningitidis, the bacterium that causes meningitis, only identifies...