Vaccine Weekly articles from May 2000

Vaccine Weekly archives from May 2000

Genetic Immunization Aimed at Metastatic Disease.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Combined induction of tumor-specific cytolytic T lymphocytes and natural killer cells provides genetic immunization against metastatic colon cancer, according to Mt. Sinai School of Medicine researchers. ...

Polyclonal Antibodies Produced by Globe H-Keyhole Limpet Hemocyanin Vaccine.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Polyclonal antibodies were produced in patients immunized with a globe H-keyhole limpet hemocyanin vaccine, according to a recent study. "We have previously reported on a carbohydrate-based vaccine program...

Human Tumor and Dendritic Cell Hybrids Generated by Electrofusion.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Hybrid cell vaccines look to be clinically feasible, suggest researchers in England. "Hybrid cells created by fusion of antigen presenting and tumour cells have been shown to induce potent protective and...

Low Immunization Rates: Is the Process the Problem?(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Mothers may be deterred from bringing their infants to be vaccinated if they feel that health professionals are unsympathetic to them and the pain inflicted on their children, suggests research in the Journal...

Phase II Peptide Vaccine Trial Conducted.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- A Phase II vaccination trial of tyrosinase peptides and granulocyte-macrophage colony-stimulating factor was conducted in patients with metastatic melanoma by researchers in Germany. "This Phase II study...

Travelers' Vaccines Don't Impair Immune Response to Hepatitis A Immunization, and Vice Versa.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Traveling abroad often means first traveling to the doctor to be immunized against various diseases. What is the effect of multiple vaccines on the immune response? Researchers at pharmaceutical company...

New Vaccine Technique Offers Hope for Asthma and Allergy Sufferers.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- For years, efforts to develop improved vaccines for asthma and allergies have been thwarted because the vaccines themselves often cause the very symptoms a person is trying to avoid. Research efforts have been...

Dendritic Cell-Based Vaccine Evaluated.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Researchers in the United States and Italy have evaluated an anti-cancer vaccine for its efficacy against ovarian cancer. Allessandro D. Santin and colleagues from the University of Arkansas and the...

Allogeneic Cell Vaccine Under Development.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Researchers in Germany are developing allogeneic cell vaccines for the treatment of renal cell carcinoma (RCC). "Because the molecular knowledge of RCC antigens is still limited, immunotherapy approaches...

Oral Vaccine and Drug Delivery Technology Licensed.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- ID Biomedical Corp. (IDBE, IDB), Vancouver, British Columbia, announced that it has signed a collaboration and licensing agreement with the University of British Columbia. The agreement covers a worldwide...

Rare Strain of Meningitis Hits U.S.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- The first U.S. cases in an apparent worldwide outbreak of a rare strain of meningitis have been reported. Government health officials said that at least three New Yorkers have come down with the type of...

CDC Panel Urges More Flu Shots.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- An advisory panel at the U.S. Centers for Disease Control and Prevention (CDC) recommended that people 50 and older, instead of just those 65 and older, receive annual flu shots. The panel said it was...

Africa Plays Catch-Up in Malaria Showdown.(Brief Article)(Statistical Data Included)
May 3, 2000... 2000 MAY 3 - (NewsRx.com) -- Most do not even hear the buzz let alone feel the bite, yet every year the mosquito-borne malaria parasite quietly kills up to two million people. The majority who die are African and under five years old. Now...

Anti-Cocaine Antibodies Evaluated in Rat Model.(Brief Article)(Statistical Data Included)
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Researchers in the United States evaluated anti-cocaine antibodies induced by a cocaine vaccine in a rat self-administration model. "The objectives of this study were to determine, first, whether changes...

Efficacy of Vaccine Evaluated in Liver Transplant Recipients.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Researchers from The Netherlands evaluated the efficacy of influenza vaccination in adult liver transplant recipients. "To assess the efficacy of influenza vaccination in immunocompromised adult liver...

Randomized Phase II Trial Compares Combination Vaccine Therapy.(in patients with metastatic renal cell carcinoma)
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- A randomized Phase II trial compared two different sequence combinations of autologous vaccine and human recombinant interferon gamma and human recombinant interferon alpha 2b therapy in patients with...

Hospital Employees Seroconvert Faster When Jet-injector Used.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- A study comparing hepatitis A virus (HAV) vaccine administration with the jet-injection technique indicates that more individuals receiving jet-injection appear to seroconvert with an anti-HAV titer >= 20...

Antibody-Dependent Cellular Cytotoxicity Induced by MUC1 Peptide Vaccine.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- A MUC1 peptide vaccine induced antibody-dependent cellular cytotoxicity in breast cancer patients, researchers from The Netherlands and the United States reported. "Human polymorphic epithelial mucin...

Method Augments Gene Therapy and DNA Vaccine Applications.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- In vivo electroporation augments DNA delivery in gene therapy and DNA vaccine applications to skin and muscle. "Electroporation is widely used in vitro to effectively introduce DNA into eukaryotic cells...

Combination Vaccine Offers Protection Equivalent to Monovalent Therapies.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- According to Jane Zuckerman at the Royal Free and University College Medical School in London, U.K., combined hepatitis A/B vaccine offers as much protection as the monovalent A and B vaccines and yields a...

Immunity Lacking in Young Adults.(measles )
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- According to a recent study, measles immunity is low among young adults now entering the health care field compared to those hired between 1983 and 1988. "Due to concern about sub-optimal vaccine-induced...

Peptide-Pulsed Dendritic Cells Induce Immune Response Against Skin Cancer.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Peptide-pulsed dendritic cell vaccines induced antigen-specific immune responses in melanoma patients, reported researchers from the United Kingdom. "Dendritic cells (DC) are professional antigen...

Infants Receiving Hepatitis A Passive Immunity from Mothers Fall Short on Protection.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Scientists at the U.S. Centers for Disease Control and Prevention (CDC) have reported research findings showing that infants who have the presence of passively transferred maternal anti-hepatitis A virus (PMA)...

Dendritic Cell Vaccines Evaluated.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Researchers from the United States evaluated dendritic-cell-based vaccines for renal cell carcinoma (RCC) using tumor antigens. "Although RCC has been shown to respond to immunotherapy, RCC-specific...

Deal Made for Virus Inactivation Technology.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- A technology to inactivate dangerous and sometimes unknown viruses in blood, plasma proteins, and other biopharmaceutical products will be made widely available following a deal announced between Amersham...

OSHA Issues Warning, Urges Preventive Measures.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- The U.S. Occupational Safety and Health Administration (OSHA) issued a warning on the danger that occupational exposure to Lyme disease poses to outdoor workers in the United States. The warning was...

Human Papillomavirus Type 68A Patent Exclusively Licensed.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Digene Corp. (DIGE), Beltsville, Maryland, announced that it has entered into an exclusive worldwide license with the Institute Pasteur, Paris, France to U.S. Patent No. 5,981,173, Genital Human Papillomavirus...

Phage-Selected Primate Antibodies Fused to Superantigens Used to Treat Melanoma.
May 17, 2000... 2000 MAY 17 - (NewsRx.com) -- Researchers from Sweden used phage-selected primate antibodies fused to superantigens for immunotherapy of malignant melanoma. "The high-molecular-weight melanoma-associated antigen, HMW-MAA, has been...

Interferon-(alpha) Demonstrates Powerful Adjuvant Effect.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Interferon-(alpha) (IFN(alpha)) has a powerful adjuvant effect when added to cancer vaccines, researchers in Italy reported. "Our group has recently demonstrated that the transduction of the IFN(alpha)1...

New Evidence Found Linking Herpes and Alzheimer's.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Researchers have long suspected a connection between the herpes virus and Alzheimer's disease. A new study provides a potential explanation that could lead to development of a vaccine to prevent the disease...

Immunity Induced by Tumor Lysate-Pulsed Dendritic Cells.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Tumor lysate-pulsed dendritic cells (DCs) induced cellular immunity in a parathyroid carcinoma patient, researchers in Germany reported. "Cytotoxic T-lymphocyte-mediated tumor immunity against major...

Intradermal RNA Inoculation Induces Anti-Tumor Immunity.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Intradermal RNA inoculation or vaccination with epidermal cells pulsed with tumor-derived RNA induces anti-tumor immunity in a murine model, according to Cornell University researchers. "The skin is...

Murine Cytomegalovirus Replication Suppressed with DNA Vaccine.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- A DNA vaccine encoding a homolog of the human cytomegalovirus pp65 suppressed murine cytomegalovirus (MCMV) replication in vivo, according to a recent study. "The cytotoxic T-lymphocyte (CTL) response...

Can the Body Trick Itself Into an Autoimmune Response to Thwart HIV?
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- When the immune system goes wrong and begins to attack the body's own cells, the result can be devastating diseases such as rheumatoid arthritis, multiple sclerosis, and Crohn's disease. But now,...

Salivary Glands Help Induce and Maintain Immune Effector Cells.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Saliva is necessary for the induction and maintenance of immune effector cells in the gastrointestinal tract of mice orally immunized with a Helicobacter pylori vaccine, researchers in Japan report. ...

Antibodies to HAV Decrease after Liver Transplantation.(hepatitis A virus )
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Recently, researchers at the Mayo Clinic reported that patients who receive liver transplants may lose their immunity to the hepatitis A virus (HAV) after orthotopic liver transplantation (OLT). According...

Murine Study Indicates Estrogen and Vaccine Combination May Prevent Disease.(multiple sclerosis and other autoimmune diseases)
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- A new study by U.S. Department of Veterans Affairs (VA) researchers offers potentially good news for women suffering from multiple sclerosis (MS) and other autoimmune diseases in which the immune system...

Blood Mercury Levels Higher in Preterm Infants Receiving Hepatitis B Vaccine.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- In the May 2000 issue of The Journal of Pediatrics, researchers report that hepatitis B vaccines containing thimerosal are elevating mercury levels in some preterm infants. Thimerosal is an organic...

Dendritic Cells Undergo Pre-Clinical Evaluation for Glioma.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- A pre-clinical evaluation of dendritic cells as treatment for intracranial glioma has been conducted. "Since glioma patients are profoundly immunosuppressed, the question arises as to whether dendritic...

Dendritic Cell Vaccine Provides Intracranial Protection.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- A dendritic cell (DC) vaccine pulsed with p53 mutant peptide demonstrates that intracranial protection against glioma is possible. "As approximately half of malignant gliomas exhibit p53 mutations, we are...

TNF(alpha) Vaccine Induces Immune Responses Against Self Proteins.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Vaccination against tumor necrosis factor alpha (TNF(alpha)) generates immune responses against self proteins, a recent study found. "We have developed a therapeutic vaccine approach that induces strong...

Scientists Prove Safety, Effectiveness of Lyme Vaccine in Children.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Researchers have demonstrated that a vaccine against Lyme disease not only is safe for children ages four to 18, but also raised children's protective antibodies against the Lyme disease organism to higher...

First Trial in Africa Completed.(HIV vaccine )
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- The first HIV vaccine trial conducted in Africa has been completed, announced researchers at the Joint Clinical Research Centre in Kampala, Uganda. The trial was funded by the U.S. National Institute for...

NIH to Sponsor Trial for HIV(+).(AIDS vaccine)
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- A clinical trial testing an HIV treatment vaccine in patients already infected with the virus will begin on or about May 25, 2000, under the sponsorship of the U.S. National Institutes of Health, officials...

Changes in Vaccine Recommended for New Season.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- The U.S. government is recommending a change in flu vaccines this coming season to fight off different virus strains likely to strike. The Type A Sydney virus has been the most common in the last three...

Alaska Proposes Boosting Number of Immunizations for Children.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Children in Alaska day care centers and schools would be required to have as many as five more immunizations under regulations proposed by the state. The new requirement would mean a few more shots for some...

Genetically Engineered Fruit May Help Make Vaccines.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- Patients may soon be able to receive vaccines from eating genetically modified fruit, according to researchers at the University of Rochester in New York. The University of Rochester, working with other...

WHO Warns of Alarming Health Situation in Sri Lanka.
May 24, 2000... 2000 MAY 24 - (NewsRx.com) -- The World Health Organization warned the international community that the health situation of the civilian population in the areas of conflict in the north of Sri Lanka is under severe threat. Lack of...

Naked DNA Delivered to Dendritic Cells Via Gene Gun.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Dendritic cells (DCs) can be successfully transfected with naked DNA using a gene gun. "Antigen delivery is a critical challenge in vaccine design," A. Larregina and colleagues from the University of...

Encouraging Preclinical Data Reported for GVAX Vaccine.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Cell Genesys, Inc. (CEGE), Foster City, California, and collaborators at Johns Hopkins University, Baltimore, Maryland, reported that in animal studies of acute leukemia, GVAX cancer vaccine, administered...

Neuroblastoma Cells Destroyed by Immune System Cells.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- MYCN-amplified neuroblastoma cells can be lysed by MYCN peptide-specific cytotoxic T lymphocytes (CTL), according to a recent study. "The effectiveness of cell-mediated immunotherapy for cancer can be...

B-Cell Lymphoma Idiotypes Induce Tumor Immunity.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Genetically engineered lymphoma cells may be a potent anticancer vaccine, suggest researchers in Germany. "Immunization with modified immunoglobulin (Ig) idiotypes (Ids) of B-cell lymphomas is an...

Asian Countries Should Look to International Community for Vaccine Programs.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- A review of hepatitis B virus (HBV) vaccination practices in Asian countries by investigators at SmithKline Beecham Biologicals shows that there is a high rate of vaccine administration in some geographical...

Therapeutic Cancer Vaccine Shows Promise in Early Clinical Study.
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Dana-Farber Cancer Institute (DFCI), Cambridge, Massachusetts, the U.S. National Cancer Institute (NCI) and Therion Biologics, Boston, Massachusetts, reported in Clinical Cancer Research promising early...

Data Presented from Collaborative Cancer Program.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Epimmune Inc. (EPMN), San Diego, California, announced that the combination of its core vaccine technology with a drug called progenipoietin (ProGP) represents a promising approach in immunotherapy for...

Antibodies Deliver T-Cell Epitopes to Antigen Presenting Cells.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Researchers in Norway reported using recombinant antibodies (Abs) to deliver T-cell epitopes to antigen presenting cells (APC). "A major objective in vaccine development is the design of reagents that...

Peptide Expressing Phage Used as Anticancer Vaccine.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- U.S. government researchers are working on a novel peptide vaccine that stimulates antibody-enhanced phagocytic cell-mediated immune responses. "For those cancer patients whose immune systems have been...

Non-Responsiveness Overcome by Targeting Antigens.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Strong antigen-specific humoral responses can be stimulated by targeting non-immunogenic antigens to CD64, according to a study presented at the conference Cellular Immunity and Immunotherapy of Cancer, held...

Vaccines for Buruli Ulcer and Tuberculosis Are in the Future.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Researchers in Belgium are working on DNA vaccines for mycobacterial diseases. "Buruli ulcer, caused by Mycobacterium ulcerans, is characterized in man by deep and necrotizing skin lesions mostly of the...

Adeno-Associated Virus-Mediated Vaccine Stimulates High-Level, Durable Immune Responses.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Breaking research from Children's Hospital in Columbus, Ohio, on a new type of genetic vaccine for AIDS which shows positive effects after immunization was presented at the 2000 Pediatric Academic Societies...

CD14 Binding Peptides Used as Anti-Lipopolysaccharides Vaccine.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Vaccination with CD14 binding peptides protected test animals from lipopolysaccharides (LPS)-induced death, researchers in China reported. "Endotoxin, or LPS of gram-negative bacteria are well known as...

Vaccine Reduces Illness and Antibiotic Use in Children Who Attend Daycare.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Vaccinating children who attend daycare with an experimental pneumococcal vaccine reduces illness as well as antibiotic use, researchers report. Ron Dagan, MD, Ben-Gurion University, and Soroka University...

Influenza Virosomes Deliver Peptides in Hepatitis C Vaccine.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Immunopotentiating reconstituted influenza virosomes (IRIVs) can be used as a non-live vaccine vector against hepatitis C virus (HCV), researchers in Switzerland reported. "The choice of a suitable...

Phase I/II Acute Myelogenous Leukemia Study Initiated.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Avax Technologies, Inc. (AVXT), Kansas City, Missouri, announced that it has initiated a Phase I/II study of L-Vax, its autologous therapeutic cancer vaccine for leukemia, in patients with acute myelogenous...

Infectious Disease Research Institute Receives $15 Million Donation from Gates Foundation.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- A vaccine for leishmaniasis - a parasitic disease that kills up to 500,000 adults and children every year - is one step closer to reality. The Infectious Disease Research Institute (IDRI) announced receipt...

Threat Lingers in Spring High-Tick Season.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Every spring, Rich Staffon spends the majority of his workweek outdoors, wading into the tall grass and forested undergrowth where deer ticks hide. He is well aware that his work as area wildlife manager...

United Nations' Campaign Suffers Setbacks.(Brief Article)(Statistical Data Included)
May 31, 2000... 2000 MAY 31 - (NewsRx.com) -- Wars, a vaccine shortage, and logistical problems have set back a campaign to eradicate polio, but the dreaded disease should be wiped out by 2005, the World Health Organization announced on May 15, 2000. ...