Vaccine Weekly articles from May 1999

Vaccine Weekly archives from May 1999

Immunogenicity of Deglycosylated SIV ENV Proteins.
May 3, 1999... Immunology (HIV) "Immunogenicity of Deglycosylated SIV ENV Proteins." Zizhi Yao. Emory University, Atlanta, Georgia. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 5R2IA142691-02. GRANT EXPIRES: September 1999....

Validation of Self-report of Influenza and Pneumococcal Vaccination Status in Elderly Outpatients.
May 3, 1999... Aging Populations Macdonald, R.; Baken, L.; Nelson, A.; Nichol, K.L. "Validation of Self-report of Influenza and Pneumococcal Vaccination Status in Elderly Outpatients." American Journal of Preventive Medicine, April 1999;16(3):173-177....

Expanded Safety and Immunogenicity of a Bivalent, Oral, Attenuated Cholera Vaccine, CVD 103-HgR plus CVD 111, in United States Military Personnel Stationed in Panama.
May 3, 1999... Cholera Taylor, D.N.; Sanchez, J.L.; Castro, J.M.; Lebron, C.; Parrado, C.M.; Johnson, D.E.; Tacket, C.O.; Losonsky, G.A.; Wasserman, S.S.; Levine, M.M.; Cryz, S.J. "Expanded Safety and Immunogenicity of a Bivalent, Oral, Attenuated...

Ebola Survivors Yield Clues For Vaccine.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The ghastly tales told by the blood of Ebola-virus victims may lead to a vaccine. Analyses of multiple blood samples from survivors and from those who died shows that the immune system must...

Mucosal Protection: Simpler Than Blood Protection?
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The hurdle may not be as high as had been thought. Evidence from primate studies suggests that intravenous, envelope-based HIV vaccines can more easily protect against mucosal challenge than...

Roadblock in Quest To Block HIV Binding.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- HIV may have armor guarding its Achilles heel. Recent studies appeared to find a weak spot in HIV's defenses: its ability to infect cells was linked to a bridge between the inner and outer...

Fetal Vaccination Successful in Baboons.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Vaccination can begin even before birth. Startling findings show that fetal baboons can be directly immunized with hepatitis B antigen. Until only recently it was a tenet of immunology that...

Vaccine Better Than IVIG in Preventing Secondary Infection.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Hepatitis A vaccine may be a better choice for the prevention of secondary hepatitis A infection than immunoglobulin. Researchers in Italy found that immunization of household contacts...

HBV Vaccine Safe/Effective for Preterm Infants.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Hepatitis B vaccination is safe in preterm infants, a report from Poland concludes. Preterm infants, especially those with very low birth weight, are at risk of hepatitis B virus infection. They...

Vaccine Raises HDL, Reduces Atherosclerosis in Vaccinated Animals.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A novel vaccine approach shows promise for raising high density lipoprotein (HDL) or "good" cholesterol levels, and preventing atherosclerosis, according to preclinical research presented by...

Vaccine Tested in Bone Marrow Transplant and Stem Cell Rescue Patients.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Biomira Inc., Edmonton, Alberta, Canada, announced that findings from clinical trials with its lead product candidate, Theratope vaccine, will be presented at the 35th annual meeting of the American...

Company Acquires Worldwide Rights to Vaccine.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- HIV-VAC, Inc., Collingwood, Ontario, Canada, has announced that they have acquired the worldwide rights to an HIV vaccine through an assignment of license agreement with Intracell Vaccines Limited....

Vaccine Provides Protection from HIV In Monkeys.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- AIDS researchers at Yerkes Regional Primate Research Center, Atlanta, Georgia, have created a DNA vaccine that protects monkeys against a formidable challenge HIV. Achieving protection with this...

Company Initiates Phase I Clinical Trial of CpG DNA for Hepatitis B.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- CpG ImmunoPharmaceuticals, Wellesley, Massachusetts, and Hilden, Germany, has initiated a Phase I clinical trial of CpG 7909, the company's lead product, for use as a vaccine immune stimulant. ...

Who Should Get the New Lyme Disease Vaccine?
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Society will reap the greatest economic benefit if the new Lyme disease vaccine is administered to people on the basis of their individual risk, rather than to all people, say authors of an article...

Study Shows Probiotic May Boost Immune System.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Lactobacillus GG (LGG), a probiotic bacterial strain, may improve the human immune response to vaccines, according to new research presented at the meeting of the Federation of American Societies for...

Respiratory Diseases Pose Growing Threat to Military Personnel.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Many factors may contribute to increased respiratory illness among U.S. troops, according to an article in the upcoming issue of Emerging Infectious Diseases, the U.S. Centers for Disease Control and...

Antigen Presentation System Could Improve Vaccine Delivery.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- BTG International Inc., Gulph Mills, Pennsylvania, announced that it has expanded its portfolio of vaccine technologies with the addition of a vaccine presentation system developed at the Veterinary...

Groups Call for Research to Investigate Link Between Autism Increase and Vaccination.
May 3, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Responding to a new report released April 15, 1999, by the California Health and Human Services Agency revealing a 273 percent increase in California children diagnosed with autism during the past...

Virus Specific T Cell Immunity In Primate AIDS.
May 3, 1999... Immunology (AIDS) "Virus Specific T Cell Immunity In Primate AIDS." Aftab A. Ahmed-Ansari. Emory University, Atlanta, Georgia. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 5ROIA127057-10. GRANT EXPIRES: August 31,...

Comparison of the Humoral and Cellular Immune Response Against MUCII-KLH and GD3-KLH Conjugate Vaccines Mixed with Various Adjuvants.
May 3, 1999... Cancer Vaccines "Comparison of the Humoral and Cellular Immune Response Against MUCII-KLH and GD3-KLH Conjugate Vaccines Mixed with Various Adjuvants." S.K. Kim, G. Ragupathi, C. Musselli and P.O. Livingston. Department of Medicine,...

HLA-A2.1K(b) Transgenic Mice Immunized against G280-9V Anchor Modified Peptide Generate G280 Native Epitope Specific CTL.
May 3, 1999... Cancer Vaccines "HLA-A2.1K(b) Transgenic Mice Immunized against G280-9V Anchor Modified Peptide Generate G280 Native Epitope Specific CTL." G.P. Linette, S. Yang, S. Longerich and F.G. Haluska. Hematology-Oncology Massachusetts General...

DNA and Protein Immunogens for SIV/HIV Vaccines.
May 3, 1999... HIV Vaccines "DNA and Protein Immunogens for SIV/HIV Vaccines." Harriet L. Robinson. Emory University, Atlanta, Georgia. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 1P01AI43045-01. GRANT EXPIRES: March 31, 2003....

A Contraceptive Peptide Vaccine Targeting Sulfated Glycoprotein ZP2 of the Mouse Zona Pellucida.
May 3, 1999... Contraception Sun, W.; Lou, Y.H.; Dean, J.; Tung, K.S.K. "A Contraceptive Peptide Vaccine Targeting Sulfated Glycoprotein ZP2 of the Mouse Zona Pellucida." Biology of Reproduction, April 1999;60(4):900-907. (CW HENDERSON PUBLISHER...

Rapid Local Expression of Interleukin-12, Tumor Necrosis Factor alpha, and gamma Interferon After Cutaneous Francisella tularensis Infection in Tularemia-immune Mice.
May 3, 1999... Tularemia Stenmark, S.; Sunnemark, D.; Bucht, A.; Sjostedt, A. "Rapid Local Expression of Interleukin-12, Tumor Necrosis Factor alpha, and gamma Interferon After Cutaneous Francisella tularensis Infection in Tularemia-immune Mice."...

In vivo Expression and Immunoadjuvancy of a Mutant of Heat-Labile Enterotoxin of Escherichia coli in Vaccine and Vector Strains of Vibrio cholerae.
May 3, 1999... Vaccine Development Ryan, E.T.; Crean, T.I.; John, M.; Butterton, J.R.; Clements, J.D.; Calderwood, S.B. "In vivo Expression and Immunoadjuvancy of a Mutant of Heat-Labile Enterotoxin of Escherichia coli in Vaccine and Vector Strains of...

New Strategies for Combination Vaccines Based on the Extended Recombinant Bacterial Ghost System.
May 3, 1999... Vaccine Development Eko, F.O.; Witte, A.; Huter, V.; Kuen, B.; Furstladani, S.; Haslberger, A.; Katinger, A.; Hensel, A.; Szostak, M.P.; Resch, S.; Mader, H.; Raza, P.; Brand, E.; Marchart, J.; Jechlinger, W.; Haidinger, W.; Lubitz, W....

Reusable, Attenuated VSV For Intranasal Vaccination.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Vesicular stomatitis virus (VSV) vectors offer several advantages as vaccine vectors, mouse studies show. Single intranasal vaccination with a highly attenuated VSV vector carrying an influenza...

Possible Plague Vaccine Antigens ID'd in Mice.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Rodents are blamed for history's devastating plague epidemics, but now they are giving researchers valuable hints for vaccine development. The etiologic agent of pneumonic and bubonic plague,...

Strain-Specific Vaccines Could Stem Meningitis Epidemics.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Strain-specific meningococcal vaccines could be effectively deployed in epidemic situations, a study led by U.S. Centers for Disease Control and Prevention (CDC) researchers suggests. The study,...

New HAV Vaccine Safe for Use in Children.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A new formulation of an inactivated hepatitis A vaccine was found to be both safe and immunogenic for pediatric use in a study from Israel. The safety and immunogenicity of a new formulation of...

Revaccination with BCG is Not a Cost Effective Strategy.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A study from the Czech Republic suggests that revaccinating with bacillus Calmette-Guerin to prevent tuberculosis is not cost effective. Researcher V.S. Pathania and colleagues from Switzerland's...

Database of Perinatal Hepatitis B Vaccinations Needed.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- There is a critical need for unified databases to coordinate hepatitis B virus perinatal vaccinations in infants, according to a report from Great Britain. Perinatal transmission of hepatitis B...

Plasmid Vaccine Encoding HCV Envelope E2 Studied.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Animal studies examined immunization with plasmids encoding hepatitis C virus envelope E2 protein. Researcher X. Forns and colleagues analyzed the humoral immune response elicited by hepatitis C...

SE47'-Specific Antibodies Inhibit P. falciparum Growth.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- An immunoglobulin inhibited malaria parasite growth by a mechanism that involved agglutination of merozoites and rupturing of schizonts. Previously, Xin-Li Pang and colleagues found that...

Bursal Disease Vaccine Useful for Chronic Hepatitis.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The Bursal Disease virus vaccine appears to be useful in the treatment of chronic viral hepatitis. Three women with chronic liver inflammation caused by hepatitis B (two) and C (one) viral...

New Approach To Vaccine Offers Promise.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Researchers said they may have come up with a new approach for an AIDS vaccine, one that would not prevent infection but might help stop the virus from being passed on. The researchers worked...

Intranasal Flu Vaccine Works in Children.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- In addition to protecting those children who had antibodies present in the nose or blood, children who received the influenza vaccine were protected against a live H1N1 vaccine virus challenge...

Most Pediatricians Follow CDC's Polio Vaccination Schedule.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The majority of pediatricians in the U.S. are following a polio immunization program of injected vaccine followed by oral vaccine recommended by the U.S. Centers for Disease Control and Prevention's...

Preventive Services and Voucher Pick-up for WIC Recipients.
May 10, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Immunization coverage rates and the performance of other clinical preventive services increased significantly for low-income children enrolled in the United States Department of Agriculture's Special...

Eradication of Tumors in Mice Transgenic for Carcinoembryonic Antigen (CEA) by Adoptive Immunotherapy.
May 10, 1999... Cancer Vaccines "Eradication of Tumors in Mice Transgenic for Carcinoembryonic Antigen (CEA) by Adoptive Immunotherapy." F.J. Primus, S. Mizobata, K. Tompkins and J.F. Simpson. Wakayama Medical School, Wakayama, Japan; Vanderbilt...

Combining, Co-Stimulatory Molecule B7.1-DNA with E7 Peptide Vaccination Enhances the Antigen's Immunological Effect.
May 10, 1999... Cancer Vaccines "Combining, Co-Stimulatory Molecule B7.1-DNA with E7 Peptide Vaccination Enhances the Antigen's Immunological Effect." H. Khong, S. Gur, J. Chun, C.J. Allegra, J.A. Berzofsky and S.N. Khleif. Medicine and Metabolism...

Immune Suppression and Immune Escape in Tumor Models.
May 10, 1999... Cancer Vaccines "Immune Suppression and Immune Escape in Tumor Models." W.M. Kast. Loyola University Medical Center, 2160 S. 1st Avenue, Maywood, Illinois 60153. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER:...

Rabies Virus Based Vectors as an HIV-1 Vaccine.
May 10, 1999... HIV Vaccines "Rabies Virus Based Vectors as an HIV-1 Vaccine." Matthias J. Schnell. Thomas Jefferson University, 1020 Walnut St., Philadelphia, Pennsylvania 19107. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER:...

Development of a Leishmania Vaccine Using Interleukin-12 as an Adjuvant.
May 10, 1999... Vaccine Development "Development of a Leishmania Vaccine Using Interleukin-12 as an Adjuvant." R.T. Kenney. Affiliation not available. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 1Z01BI03012-03. PRINCIPLE...

A Fully Synthetic Immunogen Carrying a Carcinoma-Associated Carbohydrate for Active Specific Immunotherapy.
May 10, 1999... Cancer Vaccines Loman, R.; Bay, S.; Vichierguerre, S.; Deriaud, E.; Cantacuzene, D.; Leclerc, C. "A Fully Synthetic Immunogen Carrying a Carcinoma-Associated Carbohydrate for Active Specific Immunotherapy." Cancer Research, April 1,...

Interleukin-12-secreting Human Papillomavirus Type 16-transformed Cells Provide a Potent Cancer Vaccine That Generates E7-directed Immunity.
May 10, 1999... Cancer Vaccines Hallez, S.; Detremmerie, O.; Giannouli, C.; Thielemans, K.; Gajewski, T.F.; Burny, A.; Leo, O. "Interleukin-12-secreting Human Papillomavirus Type 16-transformed Cells Provide a Potent Cancer Vaccine That Generates...

Hepatitis B Vaccination in Preterm Infants.
May 10, 1999... HBV Vaccines Golebiowska, M.; Kardassobantka, D.; Chlebnasokol, D.; Sabanty, W. "Hepatitis B Vaccination in Preterm Infants." European Journal of Pediatrics, April 1999;158(4):293-297. (CW HENDERSON PUBLISHER www.newsfile.com) --...

Development of HIV/AIDS Vaccine Using Chimeric gag-env Virus-Like Particles.
May 10, 1999... HIV Vaccines Kang, C.Y.; Luo, L.Z.; Wainberg, M.A.; Li, Y. "Development of HIV/AIDS Vaccine Using Chimeric gag-env Virus-Like Particles." Biological Chemistry, March 1999;380(3):353-364. (CW HENDERSON PUBLISHER www.newsfile.com) --...

Testing the Efficacy of a Recombinant Merozoite Surface Protein (MSP-1(19)) of Plasmodium vivax in Saimiri boliviensis Monkeys.
May 10, 1999... Malaria Vaccines Collins, W.E.; Kaslow, D.C.; Sullivan, J.A.S.; Morris, C.L.; Galland, G.G.; Yang, C.F.; Saekhou, A.M.; Xiao, L.H.; Lal, A.A. "Testing the Efficacy of a Recombinant Merozoite Surface Protein (MSP-1(19)) of Plasmodium vivax...

Adverse Effects and Sero-responses to an Acellular Pertussis/Diphtheria/Tetanus Vaccine When Combined With Haemophilus influenzae Type b Vaccine in an Accelerated Schedule.
May 10, 1999... Pediatrics Bell, F.; Heath, P.; Maclennan, J.; Shackley, F.; Shearstone, N.; Diggle, L.; Thornton, C.; Griffiths, H.; Moxon, E.R.; Finn, A. "Adverse Effects and Sero-responses to an Acellular Pertussis/Diphtheria/Tetanus Vaccine When...

Kinetic Analysis of the Effect on Fab Binding of Identical Substitutions in a Peptide and Its Parent Protein.
May 10, 1999... Vaccine Development Choulier, L.; Raufferbruyere, N.; Benkhalifa, M.; Martin, F.; Vernet, T.; Altschuh, D. "Kinetic Analysis of the Effect on Fab Binding of Identical Substitutions in a Peptide and Its Parent Protein." Biochemistry, March...

New HIV-Like SHIV Should Speed Vaccine, Drug Development.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A newly created virus is expected to speed AIDS research. The new virus affects monkeys much like HIV affects humans. Like its predecessors, the virus is a recombinant chimeric virus created by...

Protection, HIV Clearance with rgp120 ISCOM.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Immune-stimulating complexes (ISCOMs) are the best way to formulate HIV envelope antigens, a comparative trial shows. A Dutch/Swedish/U.S. research team compared T-helper immune responses in...

Vaccine Strategy Promises HIV Containment.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Elegant primate experiments point the way to a vaccine that can contain, but not prevent, HIV infection. Monkeys primed with intradermal HIV DNA and boosted with recombinant fowlpox virus...

Infection Can Occur in Urban Environments.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Lyme borreliosis can be contracted in urban areas not populated with large animals that typically serve as host for the disease vectors, according to a recent report. Lyme borreliosis is caused...

BCG Reactogenicity is an Overlooked Problem.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The clinical reactogenicity of intradermal bacillus Calmette-Guerin vaccination is a trade-off for the induction of at least partially protective immunity against tuberculosis. "It remains to be...

Vaccine Data Presented at NIH Conference.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Dr. Carl Wild, Boston Biomedica Inc., Biotech Research Laboratories, presented the latest results of Boston Biomedica's approach to HIV vaccine development at the U.S. National Institutes of Health...

Researchers Discover How To Disarm Bacteria.
May 17, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- In a major breakthrough in the treatment and prevention of infectious disease, University of California - Santa Barbara researchers have found a way to disarm microbial pathogens with the discovery...

DNA Vaccines Based on the Structure of an Anti-Idiotype Antibody (3HI) Mimicking Carcinoembryonic Antigen (CEA).
May 17, 1999... Cancer Vaccines "DNA Vaccines Based on the Structure of an Anti-Idiotype Antibody (3HI) Mimicking Carcinoembryonic Antigen (CEA)." S. Manna, P.X. Tripathi, H.-X. Qin, M. Bhattacharya-Chatterjee, K.A. Foon and S.K. Chatterjee. The Lucille...

Development of Vaccines for Genital Herpes Simplex Infection.
May 17, 1999... HSV Vaccines "Development of Vaccines for Genital Herpes Simplex Infection." S.E. Straus. Current affiliation not available. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 1Z01AI00548-10. PRINCIPLE INVESTIGATOR: S.E....

Molecular Basis of NALT-Induced Mucosal Immunity to SIV.
May 17, 1999... Mucosal Immunity (SIV) "Molecular Basis of NALT-Induced Mucosal Immunity to SIV." Jerry R. McGhee. University of Alabama at Birmingham, Birmingham, Alabama. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER:...

Antibody Response to Neuraminidase of the Influenza Virus in Children with Acute Lymphoblastic Leukemia Vaccinated Against Influenza After Chemotherapy.
May 17, 1999... Prophylaxis (Flu) "Antibody Response to Neuraminidase of the Influenza Virus in Children with Acute Lymphoblastic Leukemia Vaccinated Against Influenza After Chemotherapy." R. Rokicka-Milewskal, L.B. Brydak, M. Machala and T. Jackowska....

A Polysaccharide Vaccine for Mycobacterium tuberculosis.
May 17, 1999... TB Vaccines "A Polysaccharide Vaccine for Mycobacterium tuberculosis." J.B. Robbins. Current affiliation unavailable. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 1Z01HD01311-05. PRINCIPLE INVESTIGATOR: J.B. Robbins....

4-1BBL Cooperates With B7-1 and B7-2 in Converting a B-cell Lymphoma Cell Line Into a Long-lasting Antitumor Vaccine.
May 17, 1999... Cancer Vaccines Guinn, B.; Debenedette, M.A.; Watts, T.H.; Berinstein, N.L. "4-1BBL Cooperates With B7-1 and B7-2 in Converting a B-cell Lymphoma Cell Line Into a Long-lasting Antitumor Vaccine." Journal of Immunology, April 15,...

Immunization With Influenza A Virus Hemagglutinin and Neuraminidase Produced in Recombinant Baculovirus Results in a Balanced and Broadened Immune Response Superior to Conventional Vaccine.
May 17, 1999... Influenza Johansson, B.E. "Immunization With Influenza A Virus Hemagglutinin and Neuraminidase Produced in Recombinant Baculovirus Results in a Balanced and Broadened Immune Response Superior to Conventional Vaccine." Vaccine, April 9,...

Protection and Immune Responses Induced by Attenuated Salmonella typhimurium UK-1 Strains.
May 17, 1999... Vaccine Development Zhang, X.; Kelly, S.M.; Bollen, W.; Curtiss, R. "Protection and Immune Responses Induced by Attenuated Salmonella typhimurium UK-1 Strains." Microbial Pathogenesis, March 1999;26(3):121-130. (CW HENDERSON PUBLISHER...

Recombinant, Chimaeric Live, Attenuated Vaccine (ChimeriVax(TM)) Incorporating the Envelope Genes of Japanese Encephalitis (SA14-14-2) Virus and the Capsid and Nonstructural Genes of Yellow Fever (17D) Virus Is Safe, Immunogenic, and Protective.
May 17, 1999... Vaccine Development Monath, T.P.; Soike, K.; Levenbook, I.; Zhang, Z.X.; Arroyo, J.; Delagrave, S.; Myers, G.; Barrett, A.D.T.; Shope, R.E.; Ratterree, M.; Chambers, T.J.; Guirakhoo, F. "Recombinant, Chimaeric Live, Attenuated Vaccine...

Varicella Immunization Practices and the Factors That Influence Them.
May 17, 1999... Varicella-Zoster Virus Schaffer, S.J.; Bruno, S. "Varicella Immunization Practices and the Factors That Influence Them." Archives of Pediatrics & Adolescent Medicine, April 1999;153(4):357-362. (CW HENDERSON PUBLISHER www.newsfile.com)...

Dam Break To Loose Vaccine Flood?
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Will breaking Dam open the floodgates for new vaccines? The bacterial enzyme known as DNA adenine methylase (Dam) is involved in a number of important biological processes. Now researchers at...

HIV Immunotypes Cross Clade Barriers.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Based on the immunochemical reactivities of their outer envelopes, HIV-1 strains cluster into seven immunotypes. These immunotypes - each distinguished by unique signature peptide sequences -...

Intriguing HIV Diversity Data Raise Important Questions.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A study of HIV-1 diversity in Kenya challenges current assumptions about HIV transmission, pathogenesis, and virology. Data showing that more than 20 percent of circulating HIV-1 strains in...

CTL Vaccine Proposed for EBV.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A vaccine based on cytotoxic lymphocyte (CTL) epitopes can protect against Epstein-Barr virus (EBV), animal studies suggest. Acute EBV infection manifests as infectious mononucleosis (IM)....

Virus' Structural Differences Correlate with Pathogenesis.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A new approach to the study of dengue virus genome differences may enable a better understanding of disease pathogenesis. The understanding of dengue virus pathogenesis has been impeded by the...

Dendritic Cells Predict HBV Vaccination Success.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Animal studies suggest antigen-presenting dendritic cells have prognostic value in determining the success of vaccine therapy in hepatitis B virus carriers. In this study, researcher S.M. Akbar...

Plant-Derived Compound Shows Promise.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- An active flavonoid purified from plants is selectively toxic to parasites that cause cutaneous leishmaniasis, study findings indicate. The simple structure of 2',6'-dihydroxy-4'-methoxychalcone...

Researchers Discover How Immune System Shuts Down Faulty T Cells.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Researchers at Dana-Farber Cancer Institute (DFCI) and Harvard Medical School (HMS) have identified a mechanism the immune system uses to detect and eliminate dysfunctional T cells. Reported in...

U.S. Scientists Search for Origins of Fatal Malaysian Virus.
May 24, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- In a quarantined laboratory, U.S. scientists outfitted in plastic biohazard spacesuits and breathing through air tubes are probing a killer that has struck on the other side of the world. The...

Cancer Vaccine to p53.
May 24, 1999... Cancer Vaccines "Cancer Vaccine to p53." Hildegund C. Ertl. Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER: 1R01CA78492-01. GRANT EXPIRES: June 30,...

Immunization with Dendritic Cells (DC) Pulsed with Synthetic Peptides, Murine and Clinical Studies.
May 24, 1999... Cancer Immunotherapy "Immunization with Dendritic Cells (DC) Pulsed with Synthetic Peptides, Murine and Clinical Studies." C.J.A. Punt, I.J.M. de Vries, A.A.O. Eggert, M.W.J. Schreurs, N.H. Scharenborg, H.G.G. Verstraten, D.J. Ruiter, O.O....

Immune Suppression and Immune Escape in Tumor Models.
May 24, 1999... Cancer Vaccines "Immune Suppression and Immune Escape in Tumor Models." W.M. Kast. Loyola University Medical Center, 2160 S. 1st Avenue, Maywood, Illinois 60153. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER:...

Randomized Hepatitis B Vaccine Delivery Trial for IDUs.
May 24, 1999... HBV Vaccines "Randomized Hepatitis B Vaccine Delivery Trial for IDUs." Brian Edlin. University of California, 500 Parnassus Avenue, San Francisco, California 94143. (CW HENDERSON PUBLISHER www.newsfile.com) -- NIH GRANT NUMBER:...

Immunophenotypical and Functional Heterogeneity of Dentritic Cells Generated From Murine Bone Marrow Cultured With Different Cytokine Combinations: Implications for Anti-tumoral Cell Therapy.
May 24, 1999... Cancer Vaccines Masurier, C.; Piochedurieu, C.; Colombo, B.M.; Lacave, R.; Lemoine, F.M.; Klatzmann, D.; Guigon, M. "Immunophenotypical and Functional Heterogeneity of Dentritic Cells Generated From Murine Bone Marrow Cultured With...

Protection of Macaques Against Pathogenic Simian/Human Immunodeficiency Virus 89.6PD by Passive Transfer of Neutralizing Antibodies.
May 24, 1999... HIV Vaccines Mascola, J.R.; Lewis, M.G.; Stiegler, G.; Harris, D.; Vancott, T.C.; Hayes, D.; Louder, M.K.; Brown, C.R.; Sapan, C.V.; Frankel, S.S.; Lu, Y.C.; Robb, M.L.; Katinger, H.; Birx, D.L. "Protection of Macaques Against Pathogenic...