Vaccine Weekly articles from March 2003

Vaccine Weekly archives from March 2003

Pleural mesothelioma incidence not related to SV40-contaminated polio vaccine.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - People vaccinated against polio with vaccines contaminated with simian virus 40 do not appear to have an increased risk of pleural mesothelioma,...

Formulation parameters significantly affect vaccine microsphere performance.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The formulation of alginate microspheres can affect the hydrophobicity, cellular uptake, and macrophage toxicity of the microspheres significantly,...

Agents that target beta-amyloid show promise against Alzheimer's Disease.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "Plaques containing beta-amyloid (A-beta) peptides are one of the pathological features of Alzheimer's disease, and the reduction of A-beta is considered a primary therapeutic target. Amyloid clearance...

Therapeutic dendritic-cell vaccine effective against simian AIDS.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "An effective immune response against human immunodeficiency virus or simian immunodeficiency virus (SIV) is critical in achieving control of viral replication. Here, we show in SIV-infected rhesus...

Genetics of influenza viruses reviewed.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a recent review from the United States and England, "Influenza A viruses contain genomes composed of eight separate segments of negative-sense RNA. Circulating human strains are notorious...

Vaccine studies conducted with cloned scabies antigens.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from Australia, "Sarcoptes scabiei ('itch mite') causes scabies, a disease of considerable human and veterinary significance. Little work has been done at the molecular level...

HIV-2 genetic library vaccines ineffective in animals.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - An HIV vaccine containing a "library" of viral antigens has shown disappointing results in animal experiments, researchers in the United States report. ...

IL-2 increases CD4+ numbers but does not enhance responses to immunization.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "To ascertain whether CD4+ lymphocyte increases induced by interleukin (IL)-2 enhanced in vivo immune responses, 38 human immunodeficiency virus...

Researchers design CD4 mimic that inhibits HIV-1 entry.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "The conserved surfaces of the human immunodeficiency virus (HIV)-1 envelope involved in receptor binding represent potential targets for the development of entry inhibitors and neutralizing antibodies....

Travelers spread HIV-1 genetic variants.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "HIV-1 comprises three groups, the main (M group), 0 (outlier) and N (non-M, non-O). The M group, divided into 11 subtypes, is responsible for the global HIV-1 pandemic. Recombination between M...

Whole HIV-1 protein in liposomes prime CD8+ cells.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "Proteins may serve as ideal CD8+ T cell immunogens for human immunodeficiency virus type 1 (HIV-1) if they can be delivered to and processed through the human leukocyte antigen class I pathway,"...

Epidermal powder immunization a safe and effective vaccination method.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers at PowderJet Vaccines, Inc., have announced that hepatitis B virus (HBV) antigen can be delivered as a powdered formulation to the skin and generate...

Toll-like receptors act as sensors in immune surveillance.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from Japan, "Natural IFN-alpha/beta producing cells (IPCs) play a central role in innate immunity against microbial infections. In primary immune responses, toll-like receptors...

Genetically modified H5N1 influenza A virus vaccine candidate developed.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States and England, "Avian influenza A H5N1 viruses similar to those that infected humans in Hong Kong in 1997 continue to circulate in waterfowl and have...

Antibody subclasses in malaria-immune individuals improve vaccine design.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from France, Senegal, and the United States, "Immunity against the blood stage of Plasmodium falciparum malaria is associated with protective-type antibodies of certain classes and...

Protective efficacy of the RTS,S/AS02 malaria vaccine is not strain specific.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from England, "RTS,S/AS02 is a recombinant protein malaria vaccine that contains a large portion of the C-terminal of the circumsporozoite protein (CSP) sequence of the NF54...

Maturity allows migration of dendritic cells to lymph nodes in melanoma patients.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from The Netherlands, "Dendritic cells are the professional antigen-presenting cells of the immune system. To induce an effective immune response, these cells should not...

Feasibility of an HA2 domain-based periodontitis vaccine.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- "In a rat periodontitis model, preinoculation with the Porphyromonas gingivalis HA2 binding domain for hemoglobin provided protection from disease," researchers in the United States and Australia...

Johns Hopkins awarded $30 million to develop, introduce pneumococcal vaccine.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- The Johns Hopkins Bloomberg School of Public Health is receiving $30 million from the Global Alliance for Vaccines and Immunization (GAVI) and its financing arm, the Vaccine Fund, to accelerate the...

Researchers review immunotherapy for allergic bronchopulmonary aspergillosis.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent review from researchers in Russia and the United States, "Allergic bronchopulmonary aspergillosis (ABPA) is a severe allergic pulmonary complication caused by the saprophytic fungus...

Tolerance to bacterial lipoprotein enhances survival to many challenges.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from Ireland, "Tolerance to bacterial cell wall components is an adaptive host response. Endotoxin/LPS tolerance is characterized by a survival advantage against subsequent lethal...

OHSU researchers study vaccination protection over time.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- Oregon Health & Science University (OHSU) researchers are studying the effectiveness of the smallpox vaccine in patients who received inoculations decades ago compared with those vaccinated more...

Poll finds 54% of Americans would take vaccination.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- Michaele Tharett represents the majority view when she said she would probably get smallpox vaccinations for herself and her child if the vaccine were to become available. More than half of U.S....

Nabi receives second U.S. patent on Nicvax.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- The U.S. Patent and Trademark Office has issued Nabi Biopharmaceuticals (NABI) U.S. Patent No. 6,518,031, titled "Hapten-Carrier Conjugates for Treating and Preventing Nicotine Addiction." The...

Half of adults in U.S. unprotected.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- Home improvement expert Bob Vila, the National Foundation for Infectious Diseases (NFID), and the National Coalition for Adult Immunization (NCAI) have teamed up to challenge adults across America to...

DNA vaccine primes CD8+ T cells to control Toxoplasma gondii infection.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from Belgium, "Protective immunity against Toxoplasma gondii is known to be mediated mainly by T lymphocytes and gamma interferon (IFN-gamma). The contribution of CD4+ and...

Antigen 85A expression enhances immunogenicity to Mycobacterium tuberculosis.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "The immunogenicity of a plasmid DNA vaccine incorporating Sindbis virus RNA replicase functions (pSINCP) and expressing antigen 85A (Ag85A) from...

Heat shock/chaperone protein may act as natural adjuvant.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Heat shock/chaperone protein (HSCP)-peptide complexes can access the cross-priming pathways of antigen presenting cells (APCs), and the gp96-associated...

Cholera toxin induces migration of dendritic cells.(Brief Article)
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Intestinal M cells deliver macromolecules, particles, and pathogens into the subepithelial dome (SED) region of Peyer's patch mucosa, an area rich...

Complement component 3 required for expansion of CD8 cells in viral infections.
March 5, 2003... 2003 MAR 5 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "In addition to its established role in innate immune mechanisms, complement component C3 is also of critical importance in B cell activation and T...

Salmonella vaccines may fail to elicit antibody responses in immune individuals.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Vaccines based on Salmonella vectors are likely to be ineffective in patients with preexisting Salmonella immunity, according to a study published in...

T cell vaccine shows promise in preliminary trial.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A vaccine composed of anti-myelin T cells was well-tolerated by patients and resulted in stable or decreased values on the Kurtzke Expanded...

DNA vaccine partially protects murine fetuses from Chlamydophila abortus.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- DNA immunization with the major outer-membrane protein-encoding gene of Chlamydophila abortus offers partial protection to fetuses of pregnant mice. "The protective effect of DNA vaccination with...

Review covers recent progress in herpes simplex virus vaccine research.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Recent progress in herpes simplex virus vaccine research has been been reviewed recently. According to researchers from the United States, "Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2)...

Advances in therapeutic vaccines for neurodegenerative disorders outlined.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Research into the development of therapeutic vaccines for neurodegenerative disorders may provide new treatment options. "Insults to the central nervous system (CNS), whether of microbial or...

Meningitis risk after measles-mumps-rubella vaccination varies by vaccine strain.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- A case-crossover design has revealed that the risk of meningitis after measles-mumps-rubella vaccination varies by vaccine strain. According to recent research from Korea, "Epidemiologic study of...

Cancer vaccine one step closer.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Andreea Ioan-Facsinay from Leiden University Medical Center has attached proteins from tumor cells to antibodies. With these she treated immune cells from a mouse. These treated cells were used to...

Intra-tumoral injection of CpG inhibits tumor growth in murine colon tumors.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Intra-tumoral injection of CpG results in the inhibition of tumor growth in murine colon-26 and B-16 tumors. "Direct tumor injections of CpG (ODN #1826) into murine tumors markedly suppressed the...

Clinical trials expanded with novel vaccine.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Several additional cancer centers in the United States and Canada are enrolling patients in a clinical trial evaluating the use of a therapeutic cancer vaccine in patients with first-line metastatic...

Antigens and immunoevasins are opponents in cytomegalovirus immune surveillance.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Antigens and immunoevasins act as opponents in cytomegalovirus immune surveillance. According to recent research from Germany, "CD8+ T cells are the main effector cells for the immune control of...

Dendritic cells act as natural adjuvants and modulate immune response.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Dendritic cells can act as natural adjuvants and modulate immune response. According to recent research from India, "Dendritic cells (DCs) are potent antigen presenting cells. Mature DCs activate...

Freeze-thaw cycles do not hinder detection of measles, mumps, rubella antibodies.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- A series of freeze-thaw cycles do not hinder the detection of measles, mumps, or rubella antibodies. "We investigated the effect of multiple freeze-thaw cycles on mumps, measles, and rubella virus...

Peptides trap HIV-1 envelope glycoprotein fusion intermediate at two sites.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites. According to recent research from the United States, "Human immunodeficiency virus...

CpG 7909 is active in immunocompromised patients.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Coley Pharmaceutical Group, Inc., announced preliminary results from a physician-sponsored human clinical study. Results from the proof-of-principle study demonstrate that Coley's CpG 7909, when...

Half of U.S. adults unprotected against tetanus, diphtheria.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Home improvement expert Bob Vila and the National Foundation for Infectious Diseases (NFID) and the National Coalition for Adult Immunization (NCAI) have teamed up to challenge adults across America to...

Elimination of local macrophages in intestine prevents chronic colitis.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. According to a study from Japan, "Uncontrolled activation of T cells and macrophages is...

Outbreaks in Africa underscore urgency for increased global surveillance.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- As the world's influenza experts gathered recently in Geneva to determine next year's vaccine composition, recent outbreaks in the Democratic Republic of the Congo and in Madagascar illustrate the...

New influenza vaccination recommendations issued for children and pregnant women.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- New recommendations for influenza vaccination for children and pregnant women have been issued recently. According to a recent report from the United States, "This year the Advisory Committee on...

Recognizing influenza may be difficult in older patients with COPD.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Recognizing influenza in older patients with chronic obstructive pulmonary disease (COPD) can be difficult. According to a study from the United States, "A substudy analysis was conducted to...

Reminder systems increase influenza and pneumococcal vaccinations in elderly.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Hospital- and community-based reminder systems can increase rate of influenza and pneumococcal vaccination in hospitalized patients aged 65 years and over. "Hospitalization represents an...

Immunology of susceptibility and resistance to Leishmania major reviewed.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- A review covering the immunology of susceptibility and resistance to Leishmania major has been published. "Established models of T-helper-2-cell dominance in BALB/c mice infected with Leishmania...

Vaccine technique shows potential.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- In a demonstration of vaccine therapy's potential for treating lung cancer, Dana-Farber Cancer Institute scientists and their associates report that a prototype vaccine boosted the natural immune...

Tumor necrosis factor alpha regulates development of Lyme osteoarthritis.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Destructive arthritis in vaccinated interferon gamma-deficient mice challenged with Borrelia burgdorferi is modulated by tumor necrosis factor alpha. "We found that Borrelia burgdorferi-vaccinated...

No evidence for immune system overload after triple jab MMR.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- There is no evidence that the triple MMR (measles, mumps, and rubella) vaccine causes immune system overload and makes children more vulnerable to serious bacterial infection, finds a new study. If...

Association found between class I HLA-B alleles and antibody levels.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- An association between class IHLA alleles and antibody levels was found after a single dose of measles vaccine. According to recent research from the United States, "Despite the success of the...

Immunotherapeutics companies announce plans to merge.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN), and Anosys, Inc., announced that they have preliminarily agreed to merge their operations to create a combined company focused on the field of immunotherapeutics and products...

MicroTest wins government contract to assist in vaccine manufacturing.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- MicroTest Laboratories (MTL) announced that it has received a $1.22 million contract to provide aseptic manufacturing support for the production of a series of recombinant vaccines against botulinum...

UNICEF and partners to immunize Iraqi children.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- In the shadow of ongoing international debate over a potential conflict in Iraq, health workers were scheduled to fan out across the country to immunize more than 4 million Iraqi youngsters against...

Immunity from old vaccinations may linger.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Preliminary research shows people vaccinated against smallpox decades ago could still have a surprising amount of immunity. Oregon Health & Science University researcher Mark Slifka and his lab...

Poland to purchase more than 1 million doses of vaccine.(Brief Article)
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Poland will soon acquire more than 1 million doses of smallpox vaccine as a part of the nation's preparations against potential terrorist threats, the prime minister said. Leszek Miller, who,...

Vaccination reactions reported.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- Three serious reactions have been reported out of more than 100,000 military vaccinations against smallpox, the Army's deputy director for military vaccines says. Col. John D. Grabenstein told an...

Protein from Streptococcus strain G148 induces strong antibody response.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- B- and T-cell epitopes of BB, a carrier protein derived from the G protein of Streptococcus strain G148 induces a strong antibody response. According to a study from France, "Most conventional...

U.S. vaccines could protect against group A streptococcal Mexican strains.
March 12, 2003... 2003 MAR 12 - (NewsRx.com & NewsRx.net) -- M protein gene type distribution among group A streptococcal clinical isolates recovered in Mexico overlaps with type distribution within the United States. According to a study from the United...

Flt3 ligand performs poorly as adjuvant for prostate cancer vaccine.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The number of dendritic cells stimulated by an MHC class I peptide vaccine consisting of the E75 HLA-A2 epitope from HER-2/neu were increased when...

Simulations show health workers, not public, should obtain smallpox vaccinations.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A simulation of various scenarios involving terrorist attacks using smallpox virus indicated that immunization of healthcare workers is likely to be...

Viral transcriptional regulator elicits antibody response.(Brief Article)
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Viral transcriptional regulator elicited an antibody response. "The E2 transcriptional activator of the human papillomavirus regulates the expression of most viral transcripts. Its binding to...

Canadian researchers evaluate 7-valent pneumococcal conjugate vaccine.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- A pharmacoeconomic evaluation of a 7-valent pneumococcal conjugate vaccine was conducted in Canada. "The objective of this study was to evaluate the projected health benefits, costs, and...

Should cell culture smallpox vaccine be offered to general population?
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- The new cell culture smallpox vaccine should be offered to the general population, some researchers say, others say no. According to researchers in the United States, reporting in Reviews in...

Occult orbital neuroblastoma detected after antitumor vaccine.(Brief Article)
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- An occult orbital neuroblastoma was detected after administration of an antitumor vaccine. According to a study from the United States, "A 6-year-old girl with neuroblastoma developed swelling and...

Experimental AIDS vaccine seen helping some.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- A highly anticipated experimental AIDS vaccine failed to protect most people from the disease in its first major trial, although it did show promise in protecting blacks and Asians, its developer says....

Large animal models should have role in immunological research.(Brief Article)
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Researchers should consider the relevance of large animal models when conducting immunological studies. "The main advances in immunology have been forged or underpinned by animal experiments....

Distrust may lead blacks to be wary of AIDS vaccine testing.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Researchers trying to learn more about why an AIDS vaccine appeared to work well in a small number of black volunteers may have trouble finding people for further studies, advocates and educators warn....

DNA immunization offers new opportunities in vaccine research.(Brief Article)
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- DNA immunization offers new opportunities in vaccine research. "A novel class of vaccines, based on the immunization with 'naked' DNA, may hold the promise of protecting against human disease...

Strain-related responses to DNA delivery to somatic cells reviewed.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Researchers present an overview of the delivery of deoxyribonucleic acid (DNA) to somatic cells. According to recent research from the United States, "There is great potential in successful...

Dendritic cell ability to direct T helper cells dependent on microbial signals.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals. According to recent research from England, "Dendritic cells (DC) initiate T...

AIDS vaccine fails, long HIV fight still ahead.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Though a once-promising AIDS vaccine candidate failed a significant test, scientists and activists still applauded the biotechnology company for conducting an ethical experiment and said the results...

Trial results are important step forward in developing effective vaccine.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Preliminary results of a large-scale trial of a candidate AIDS vaccine announced by the U.S.-based biotechnology company VaxGen suggest that it is possible to protect some individuals from HIV...

Myelocytes prevent proliferation of cytolytic T cells.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- c-kit+ FcR+ myelocytes are increased in cancer and prevent the proliferation of fully cytolytic T cells in the presence of immune serum. According to a study from the United States, "Immunogenic...

Researchers detail response to latest immunoglobulin shortage.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Researchers detail response to latest shortage of IVIG. According to recent research from the United States, "In fall 1997, a shortage of intravenous immunoglobulin (IVIG) developed in the United...

Skeletal muscle can be used for nonviral gene delivery.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Skeletal muscle is a virtual protein factory and can be used for non-viral gene delivery. "Ever since the publication of the first reports in 1990 using skeletal muscle as a direct target for...

Tumor vaccine produces remission in patients with advanced cancer.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Cancer cells made to secrete lymphotactin and interleukin (IL-2) have generated complete or partial remission in patients diagnosed with advanced...

European phase I/II trial of NicVAX begins.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Nabi Biopharmaceuticals (NABI) announced that enrollment has begun in its phase I/II clinical trial of NicVAX (nicotine conjugate vaccine) in smokers, ex-smokers, and nonsmokers. The trial is...

HHS announces contracts to develop safer vaccines.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- U.S. Health and Human Services Department Secretary Tommy G. Thompson has announced the award of two contracts totaling up to $20 million in first-year funding to develop safer smallpox vaccines. ...

Health care workers turning down vaccine.
March 19, 2003... 2003 MAR 19 - (NewsRx.com & NewsRx.net) -- Despite President Bush's recommendation, hospitals and health care workers are turning down the smallpox vaccine, worried about the inoculation's side effects and unconvinced that the threat of a...