Vaccine Weekly articles from March 2000

Vaccine Weekly archives from March 2000

DNA Shuffling Improves Immunogenic Properties of Hepatitis Vaccine.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Molecular breeding can be used to increase the immunogenicity of a DNA vaccine encoding the hepatitis B surface antigen, researchers from the United States reported. "Molecular breeding is a powerful...

Adjuvant Active Specific Immunotherapy for Stage II and III Colon Cancer.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Adjuvant active specific immunotherapy for stage II and III colon cancer with an autologous tumor cell vaccine was evaluated in a clinical trial, reported researchers from the United States. "A randomized,...

DNA Vaccine Induces Neutralizing Antibody and Memory B Cells.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- A DNA vaccine expressing dengue type 2 virus premembrane and envelope genes induced neutralizing antibody and memory B cells in mice, reported researchers from Japan. "A dengue DNA vaccine candidate was...

gp120-Depleted HIV-1 Antigen Stimulates in vitro Immune Function.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- In vitro immune function was realized after vaccination with an inactivated, gp120-depleted HIV-1 antigen with immunostimulatory oligodeoxynucleotides, researchers from the United States reported. "We...

CD8(+) T Lymphocytes Not Essential to DNA Flu Vaccine.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Contrary to convention wisdom, the CD8(+) T lymphocytes are not critical in the operation of DNA-based influenza vaccinations, say researchers. "DNA vaccination offers the advantages of viral gene...

Epitope-Displaying Bacteriophages Used in Anti-IgE Vaccine.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Epitope-displaying bacteriophages can be used to induce an epitope-specific antibody response via oral immunization, suggested researchers from Switzerland. "An essential requirement for oral vaccines is...

Oral Administration of Mycobacterium bovis BCG Effective.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- The oral or intragastric administration of Mycobacterium bovis bacillus Calmette-Guerin (BCG) induced similar levels of protective immunity as that induced by immunization via the subcutaneous route, suggested...

Immunogenicity and Safety of TB Proteins Tested in Primates.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Secreted protein-based preparations may represent promising vaccine candidates for Mycobacterium tuberculosis (TB), suggested researchers from the United States. "The development of improved vaccines is...

AB0 Blood Group Antigens on Viruses Serve as Targets for Neutralizing Antibodies.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- AB0 blood group antigens serve as targets for neutralizing natural antibodies against viruses, reported researchers from the United Kingdom and the United States. Research has shown that terminal...

Novel Formulations Protect Microencapsulated Antigens from Degradation.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Novel formulations of microparticles can protect microencapsulated antigens from degradation and therefore elicit enhanced immune responses, according to new research. "Immunization with antigens...

Novel Vector Expresses Multiple HIV-1 Antigens.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- A novel vaccine strategy incorporates several HIV-1 accessory genes as part of a single, multi-component immunogen, researchers from the United States reported. DNA vaccination generates both humoral and...

HIV/SIV Vaccine Studied in Primate Model.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- HIV/SIV can be attenuated through the gain of IkappaB-(alpha)S32/36A, a proteolysis-resistant inhibitor of NF-kappaB, reported researchers from Italy. "Live-attenuated SIVs deleted of accessory genes such...

DNA Vaccines Studied for Emerging Arenaviruses.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Researchers from the United States are actively exploring potential DNA vaccines for prevention of Lassa virus. "Lassa virus is a rodent born arenavirus endemic to West Africa which causes Lassa fever in...

CD4 T Cells Contribute to Protective Immunity.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- CD4 T cells contribute to protective immunity to Plasmodium chabaudi infection after apical membrane antigen-1 immunization, reported researchers in Australia. "Apical membrane antigen-1 (AMA1) is a...

Vaccine Data from Largest-Ever Study Presented.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Corixa Corporation, Seattle, Washington, announced that data from a Phase III, randomized trial to evaluate Corixa's therapeutic vaccine for the treatment of melanoma, Melacine, were presented February 17,...

New Technique Uses Topical Application of Vaccine Antigens.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- A new immunization technique uses topical application of vaccine antigens to the skin. "Transcutaneous immunization (TCI) is a new technique that utilizes a topical application of vaccine antigens in a...

DNA Vaccine Uses Isolated Milk Proteins as Delivery Vehicle.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Isolated milk proteins may be novel delivery systems for DNA vaccines. Research has shown that DNA vaccines can induce high-titer serum antibodies to a variety of different antigens, including viral,...

HIV Vector Could Lead to Targeted Gene Transfer.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- An HIV vector could be useful for targeted gene transfer into CD4(+) T cells. This finding was presented by researcher Koichi Miyake and colleagues from Tokyo, Japan's Nippon Medical School at the...

Lentiviral Vectors May Further HIV Vaccine Search.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Lentiviral vectors expressing viral or tumor antigens may further the search for an HIV vaccination strategy. The life cycle of HIV provides many potential intervention strategies for gene therapy. In this...

U.S. Military Rejects Call To Suspend Anthrax Shots.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- A congressional report on February 17, 2000, recommended the U.S. military suspend mandatory anthrax vaccine shots planned for all 2.4 million active and reserve troops. The U.S. Department of Defense quickly...

Report Card Measures Progress of Hepatitis A Endemic States.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- In honor of the one-year anniversary of the landmark recommendation by an advisory body to the U.S. Centers for Disease Control and Prevention (CDC) encouraging states with high incidence of hepatitis A to...

Collaboration Will Work on Vaccine.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- Targeted Genetics Corp. is collaborating with two institutions to develop a vaccine to prevent AIDS, the three concerns said in a joint statement on February 16, 2000. Seattle, Washington-based Targeted...

NewsRx.com Daily Health, Medical, and Biotech News Site Opens at www.NewsRx.com with $30 Million Giveaway.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- After months of anticipation by current subscribers, NewsRx.com has launched its daily health and medical news site with tiered content for professionals and consumers at www.NewsRx.com. "NewsRx.com...

Ex-CDC Official Denies Wrongdoing in HIV Vaccine Deal.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- A former U.S. Centers for Disease Control and Prevention official on February 17, 2000, denied any wrongdoing in the allocation of $8 million to study an HIV vaccine made by the company that now employs him....

U.S. Government Agency Signs Plan on Vaccine.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- The U.S. National Institute of Allergy and Infectious Diseases (NIAID) said on February 14, 2000, that it had signed an agreement with a non-profit group to use some funds from the Bill and Melinda Gates...

FDA Approves Vaccine for Children.(Brief Article)(Statistical Data Included)
March 8, 2000... 2000 MAR 8 - (NewsRx.com) -- A vaccine to protect infants and toddlers from life-threatening meningitis and blood poisoning caused by pneumococcal bacteria won government approval on February 17, 2000. The vaccine, called Prevnar,...

A(beta) Peptide Vaccine Has Therapeutic Potential.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Researchers from the United States are developing a vaccine strategy to prevent and treat Alzheimer's disease. "Alzheimer's disease (AD) is a leading cause of dementia and death in the elderly," wrote...

Young IV Drug Users Not Being Vaccinated Against HBV.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Health officials are missing the chance to immunize young injection drug users against hepatitis B virus, a study from San Francisco, California, suggests. Researcher K.H. Seal and colleagues from the...

Anti-Idiotype Antibody Vaccine Mimics Disialoganglioside GD2.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- TriGem used as a cancer vaccine has minimal toxicity and generates robust and specific IgG immune responses against the disialoganglioside GD2, reported researchers from the United States. "To determine...

Immune Responses Mediated Via Antigen-Presenting Cells.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- DNA-based vaccines induce Th1-biased immune responses mediated via action on professional antigen-presenting cells (APC) which up-regulate IL-12 production, reported researchers from Japan. "The efficacy...

Immune Responses to Varicella Zoster Vaccine Evaluated.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Specific antibody responses possible with DNA vaccine encoding genes for the varicella zoster virus (VZV), researchers from the United States reported. "In this study we sought to examine the mechanism by...

New Monoclonal Antibodies Combat Virus in Mice.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- The deadly Ebola virus didn't kill laboratory mice protected by newly developed monoclonal antibodies to the virus glycoprotein, report U.S. army medical researchers. J.A. Wilson and colleagues, writing...

Gender Differences in Viral Diversity at Time of Infection Affect Vaccines.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Important differences in the transmitted virus populations between genders could affect HIV vaccine efficacy, researchers from the United States reported. "To develop an HIV-1 vaccine with global...

Protection Elicited in Macaques by Multiple Gene-Deleted SHIV Vaccine.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Gene-deleted live SHIV vaccine protects macaque monkeys from HIV infection, reported researchers from Japan. "To evaluate the potential of SHIVs as anti-HIV-1 live vaccines, we constructed two...

Combined Hepatitis A and B Vaccine is Cheaper in Long Run.(Statistical Data Included)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- A combined hepatitis A and B vaccination strategy, while initially more expensive, can actually save public health dollars in the long run according to a review of such strategies. The report was one of...

Antigen is Functionally Conserved Across Plasmodium Species.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- The malaria vaccine antigen MSP-1(19) is functionally conserved across distantly related Plasmodium species, reported researchers from Australia. "The C-terminal region of Plasmodium falciparum merozoite...

Potential Vaccine Reduced Damage Due to Seizure and Stroke in Rat Study.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Researchers have developed an oral genetic vaccination that unleashes antibodies at a subunit of a specific brain protein, reducing the neurological damage caused by seizure and stroke in rats. The...

Gene Therapy May Heal Some Injuries.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- An injection of a therapeutic gene may someday help to heal an athlete's badly damaged muscle, fractured leg, or blown-out knee, researchers say. In lab animals, gene therapy has knit together broken...

Distinct Lymphocyte Subsets Responding to BCG Identified.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Researchers from Italy identified distinct lymphocyte subsets responding to subcellular fractions of Mycobacterium bovis bacille Calmette-Guerin (BCG) vaccine. "In order to investigate the ability of...

Researchers Design Rapid Test for Vaccine Candidates.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Researchers have begun an informatics approach to testing epitope-containing plasmid constructs and their ability to provide a protective immune response against Mycobacterium tuberculosis (Mtb). Anthony...

DNA Priming is Required for Enhancing DNA Immunity.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- A report from Korea could advance the search for an effective vaccine against hepatitis C virus infection. Researcher M.K. Song and colleagues from Pohang University of Science and Technology found that...

Intranasal Administered Enterotoxins Cause Severe Side Effects.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- The use of enterotoxin as an intranasal adjuvant is associated with severe side effects, reported researchers from Belgium. "Escherichia coli heat-labile toxin (LT) and various LT derivatives have been...

DNA Vaccine Protects Against Organ-Specific Autoimmunity.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- DNA vaccination can protect against organ-specific autoimmunity, reported researchers from Sweden and Germany. "DNA vaccines which encode encephalitogenic sequences in tandem can protect from subsequent...

Pros and Cons Discussed at Conference.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Although DNA vaccines may have much to offer, getting them from the bench to the bedside is a big leap, researchers from the United Kingdom reported. "Conventional vaccines are normally based on killed or...

SF162deltaV2 Envelope Could Further AIDS Vaccine Search.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- The generation of T-helper and neutralizing-antibody responses in macaques immunized with the SF162deltaV2 envelope using a bimodal DNA/protein vaccination protocol was the subject of a presentation by...

Mammalian Cell Proteins Investigated for TB Vaccine.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- In a recent study, researchers reported that two mammalian cell entry (Mce) proteins, Mce1A and Mce1E, were immunologically active during infection with Mycobacterium tuberculosis (Mtb). S. Ahmad and...

Allopeptide-Pulsed Host DCs Induce Allograft Tolerance.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- According to recent research from the United States, donor-specific tolerance to rat cardiac allografts can be induced by allopeptide-pulsed host dendritic cells. "Presentation of peptides either by...

U.S. National Institutes of Health Launches ClinicalTrials.gov Web Site.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- The U.S. National Institutes of Health announced the launch of the first phase of a consumer-friendly database, ClinicalTrials.gov, with information on more than 4,000 federal and private medical studies...

Drug Companies To Donate Vaccines.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Four major drug companies planned to announce at the White House on March 2, 2000, that they are donating millions of doses of vaccines - worth more than $150 million - to combat infectious diseases in needy...

Health News Mega Site www.NewsRx.com Offer Jams Web Site; NewsRx.com Named Official Online News Sponsor of eHealthcareWorld.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- The $30 million health news giveaway announced by NewsRx.com at www.NewsRx.com resulted in an instantaneous onrush. "We announced the giveaway at 7:30 a.m. Traffic peaked immediately and by 8:00 a.m. the...

Meningitis C Vaccine Approved in U.K.(Brief Article)
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- Chiron Corp. announced that its meningitis C vaccine was approved by regulators in the United Kingdom. Chiron, based in Emeryville, California, said it expects to begin shipping the vaccine, under the...

New Strategies for Bovine Tuberculosis Needed.
March 15, 2000... 2000 MAR 15 - (NewsRx.com) -- New vaccines strategies to help control bovine tuberculosis are needed, reported a researcher from the United Kingdom. "Bovine tuberculosis (TB) is caused by Mycobacterium bovis, a bacterium closely...

DNA Vaccines Can Protect Newborns.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- DNA vaccines can protect newborns from viral diseases that conventional vaccines cannot, say researchers from the Scripps Research Institute in the March 2000 issue of the Journal of Virology. The...

Porous Chitosan Microparticles Absorbed through Peyer's Patches.
March 22, 2000... 2000 MAR 22 - (NewsRx.com) Oral vaccines may take advantage of porous chitosan microparticles which are transported in vivo through Peyer's patches, reported researchers from The Netherlands. "Although oral vaccination has numerous...

Human Autoantibodies to CEA Induced By Vaccinia-CEA Vaccine.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Human autoantibodies to carcinoembryonic antigen (CEA) can be induced by a vaccinia-CEA vaccine, researchers from the United States reported. "CEA is a well-characterized oncofetal glycoprotein whose...

Epitopes Recognized by Monoclonal Antibodies May Advance HIV Vaccine Search.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Epitopes recognized by three monoclonal antibodies may hold the key to an effective anti-HIV vaccine. Although maternal HIV-1 transmission occurs during gestation, intrapartum and postpartum (by...

Rabies Virus-Based Vaccine Against HIV Created; Other Viruses Next.
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Researchers at Jefferson Medical College, Philadelphia, Pennsylvania, are using a new ploy to combat HIV, the AIDS virus: rabies. Scientists have devised for the first time an HIV vaccine using a...

Single Dose of GM-CSF May Improve HBV Vaccination Efficacy.
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- A single dose of granulocyte-macrophage colony stimulating factor prior to hepatitis B virus vaccination may improve the efficacy of the vaccine in patients undergoing hemodialysis. Patients on...

Boosters Not Needed Following HBV Vaccine at Birth.
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- An 11-year follow-up of newborns vaccinated against hepatitis B virus found that immunity was long-lasting and booster immunization was not necessary. In this study, X. Lin and colleagues from China's...

Research Needed On Natural Malaria-Host Interactions.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Despite advances in malaria vaccine research, more studies are needed on the role the environment plays in the natural interaction between host and parasite, say researchers. "The search for a cytotoxic T...

Complete Genome Sequence of Meningitis Bacterium Determined.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Chiron Corporation announced that its research team located in Siena, together with collaborators at The Institute for Genomics Research (TIGR) in Rockville, Maryland, and the University of Oxford, have...

Anti-Cocaine Vaccine Produces Antibodies and Is Safe.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- A therapeutic cocaine vaccine designed to suppress the high addicts get from taking cocaine is safe and produced cocaine antibodies in humans, a Yale University study finds. Thomas Kosten, MD, principal...

HLA-Restricted Immune Response Relevant to Vaccine Design.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- HLA-restricted immune responses are relevant to the design of mycobacterial vaccines, researchers from Kuwait reported. "Identification of mycobacterial antigens that are recognized by CD4(+) Th1 cells in...

Gait Disturbance after MMR Vaccine Interpreted as Cerebellar Ataxia.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- A follow-up study determined that gait disturbance noted after measles-mumps-rubella vaccination at 15 months of age can be interpreted as cerebellar ataxia, reported researchers from Denmark. "Measles,...

Is Vaccination Associated with Autoimmunity?(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- The jury is still out on whether vaccination may cause autoimmunity in humans, reported researchers from Israel. "The question of a connection between vaccination and autoimmune illness (or phenomena) is...

Antibiotics Suppress Vaccine-Induced Antibody Responses.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Some antibiotics have an immunosuppressive effect on vaccine-induced antibody responses, reported researchers from China. "Antibiotics are well-known to have effects on the immune system as shown by in...

DNA Priming Followed by Protein Boosting Enhances Immune Response.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- DNA priming followed by protein boosting enhances the immune response of the vaccine to acceptable levels, reported researchers from Taiwan in a study on foot-and-mouth disease. "Foot-and-mouth disease...

Lentiviral Vectors May Represent Immunization Strategy.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Lentiviral vectors expressing viral or tumor antigens may represent an immunization strategy for HIV, researchers from the University of California at San Diego suggest. Flossie Wong-Staal and colleagues...

RTS,S Malaria Vaccine Induces Specific Opsonizing Antibodies.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Circumsporozoite protein (csp)-specific opsonizing antibodies (Abs) contribute to the protection induced by the RTS,S malaria vaccine, researchers from the United States and Belgium reported. "Prior to...

DNA Family Shuffling Used to Improve Immune Response.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Researchers have used DNA Family Shuffling to improve antiviral activity in human cells. Molecular breeding, a powerful process that recombines single genes or gene families, can rapidly evolve desired...

Oral Delivery of Peptide Vaccines Explored.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- A lipid-core-peptide delivery system may have merit for oral delivery of synthetic peptide vaccines, researchers from the United Kingdom reported. "In order for synthetic peptide vaccines to be delivered...

HIV Vector Studied in CD4(+) Cells.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- An HIV vector may be useful for targeted gene transfer in CD4(+) T cells. This was the finding of Koichi Miyake and colleagues from Tokyo, Japan's Nippon Medical School presented at the "Gene Therapy of...

Proteosomes Are Safe and Effective Adjuvant/Delivery Vehicles.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Proteosomes are safe and effective adjuvant/delivery vehicles for the induction of mucosal and systemic immune responses, reported researchers from Canada and the United States. "Proteosomes are...

Dendritic/Cancer Cell Fusion Technology Licensed.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Genzyme Molecular Oncology, Framingham, Massachusetts, announced that it has exclusively licensed dendritic/cancer cell fusion technology for all therapeutic uses from Dana-Farber Cancer Institute. This...

Antitumor Immunity Induced by Indomethacin and Cancer Vaccine.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Combination immunotherapy and indomethacin induced anticancer immunity in murine cancer models, researchers from Israel reported. "Irradiated tumor cells given, together with indomethacin, to syngeneic...

Group Supports UNAIDS Ethical Guidelines on AIDS Vaccine Trials.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Seth Berkley, MD, International AIDS Vaccine Initiative (IAVI), issued the following statement after UNAIDS released a new set of international ethical guidelines on AIDS vaccine research: [helv] An...

Vaccine Candidate Announced.
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- Cel-Sci Corp., Vienna, Virginia, announced that it has identified a novel vaccine candidate for the treatment of HIV. The vaccine would be used in conjunction with antiviral drug therapy to stimulate an...

Global Vaccine Alliance Draws Overwhelming Interest from Developing World.
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- The first phase of a new global alliance to increase vaccine coverage among the world's poorest children is drawing a surge of interest from developing country health officials. The Global Alliance for...

Recipe for the Northern Hemisphere Flu Vaccine Released.(Brief Article)
March 22, 2000... 2000 MAR 22 - (NewsRx.com) -- The composition of the vaccine for the November 2000-April 2001 influenza season in the Northern hemisphere has been determined and communicated to vaccine manufacturers by the World Health Organization...

Antigen-Loaded Dendritic Cells Induce Tumor-Specific CTL in Melanoma Patient.(Brief Article)
March 29, 2000... 2000 MAR 29 - (NewsRx.com) -- Gene-modified dendritic cells that transiently express tumor-associated antigens have potential use as in vivo cancer vaccines, researchers from the United States reported. "Immunization with...

Testing Begins for New Vaccine Designed to Prevent Recurrence of Brain Tumors.(Brief Article)
March 29, 2000... 2000 MAR 29 - (NewsRx.com) -- Researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have launched a study of a new vaccine intended to prevent the return of malignant brain tumors that have been surgically...

Unsafe Injection Practices Have Serious, Large-Scale Consequences.(Brief Article)
March 29, 2000... 2000 MAR 29 - (NewsRx.com) -- Unsafe injection practices throughout the world result in millions of infections which may lead to serious diseases and death. Each year over-use of injections and re-use of dirty syringes and needles...

Co-Encapsulation of Antigen and Plasmid DNA Improves Response.(Brief Article)
March 29, 2000... 2000 MAR 29 - (NewsRx.com) -- Co-encapsulation of protein antigen with plasmid DNA antigen improves the immune response of DNA vaccines, researchers from the United Kingdom reported. "The use of plasmid DNA in vaccine technology is...

Flu Shot May Cut Heart Attack Risk.
March 29, 2000... 2000 MAR 29 - (NewsRx.com) -- Getting an annual influenza shot may do more than represent a shot in the arm to preventing the flu. It might also reduce heart attacks. A new study suggests that heart patients may significantly reduce...