Vaccine Weekly articles from June 2003

Vaccine Weekly archives from June 2003

Costimulatory molecule vaccine effective against B-cell lymphoma in mice.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A vaccine containing recombinant fowlpox virus encoding B7-1, intercellular adhesion molecule-1, and leukocyte function-associated antigen-3 elicited...

Vaccination against hepatitis A elicits humoral and cellular immune responses.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Vaccination against hepatitis A stimulates release of both interferon-gamma and interleukin-10, according to a report in Pharmacotherapy. Mary S....

Hepatitis A vaccine does not affect course of HIV.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Hepatitis A vaccination did not affect the course of HIV infection in HIV-positive patients. "The safety and immunogenicity of inactivated hepatitis A (HepA) vaccine was assessed in 133 hepatitis A...

DNA vaccine and interleukin-12 plasmid protect against hepatitis C.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Double boosts of a DNA vaccine along with interleukin-12 protected mice against hepatitis C. "We evaluated the prime-boost immunization consisting of hepatitis C virus (HCV)-core expression plasmid...

Self-report of influenza and pneumococcal vaccinations trustworthy.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Patients rarely tell a healthcare provider that they did not receive an influenza or pneumococcal polysaccharide vaccination when they actually did receive it. "National surveys of adult...

Vaccinia virus vaccine stable whether diluted or undiluted.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The stability of the vaccinia virus vaccine Dryvax was similar whether it was stored diluted or undiluted. According to a study from the United States, "The stability of Dryvax vaccine was examined...

Adverse events occur in British service personnel after anthrax vaccination.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Adverse medical events have occurred in British service personnel after receiving anthrax vaccination. According to a study from England, "The safety of the UK anthrax vaccine in British service...

Vaccination halts progression in animal studies.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Researchers at the University of California, San Diego (UCSD), School of Medicine have shown in mice that a vaccine for pneumonia also triggers elements of the immune system to reduce atherosclerosis,...

Antibody mimic CO17-1A elicits immune response in colorectal cancer patients.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- An antibody mimicking the gastrointestinal carcinoma-associated epitope CO17-1A elicited an immune response in colorectal cancer patients. According to published research from the United States,...

Lipopolysaccharide not needed for T-cell response to DNA vaccination.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Lipopolysaccharide was not needed to induce T-cell responses to a DNA vaccine. According to a study from the United States, "Bacterial products, including lipopolysaccharide (LPS), are potential...

Vaccine producer provides updates on corporate programs.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Acambis plc (ACAM) announced its results for the first quarter ended 31 March 2003. During the first quarter of 2003, there were a number of positive developments relating to our smallpox vaccine...

HIV-1 escapes attack by changes in carbohydrate structures.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- HIV-1 escapes attack by changing the structure of its carbohydrate moieties. According to recent research from the United States, "HIV-1 readily mutates to escape the immune response, evolving in...

Four hepatitis B prevention programs evaluated.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Four hepatitis B prevention programs in four states in the U.S. were evaluated for effectiveness. According to recent research from the United States, "During 1992-2000, the authors studied...

Infection in kidney transplant patient caused by novel mutants of hepatitis B.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- An infection in a renal transplant recipient caused by novel mutants of hepatitis B virus occurred despite protective anti-hepatitis B surface antibodies. "A renal transplant recipient became...

Viral Hepatitis Prevention Board presents findings on hepatitis B vaccines.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The WHO Viral Hepatitis Prevention Board recently presented their findings on hepatitis B vaccines. According to recent research published in the journal Vaccine, "The status and likely impact of...

Experts examine global progress in vaccines.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Many of the world's vaccine scientists met at the National Foundation for Infectious Diseases' (NFID) Sixth Annual Conference on Vaccine Research to present the latest research on vaccines against...

Nasal vaccine delivery platform data presented at vaccine conference.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Carrington Laboratories, Inc., (CARN) announced that results of an initial study sponsored by its subsidiary DelSite Biotechnologies, Inc., were presented at the 6th Annual Conference of Vaccine...

Immunity to influenza boosted by H5N3 A/Duck/Singapore/97 vaccine.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Immunity to influenza H5N1 was boosted by using an MF59-adjuvanted H5N3 A/Duck/Singapore/97 vaccine in humans. "In 1997, influenza A/Hong Kong/97 (H5N1) emerged as a potential human threat. In...

Lipopolysaccharide epitope protects against meningococcal bacteremia.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- A highly conserved Neisseria meningitidis inner-core lipopolysaccharide epitope conferred protection against experimental meningococcal bacteremia. According to a study from England, "Inner-core...

Immune cells may help deliver cancer vaccines for children.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- In a finding that could lay the groundwork for future cancer vaccines for children, cancer researchers working in cell culture have shown that modified immune cells can efficiently deliver genetic...

Greenland vaccination program a success story.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The Greenland childhood vaccination program is a success story, according to a report in the journal Vaccine. According to recent research from Denmark, "To assess coverage rates of standard...

Bordetella pertussis protein pertactin induces immune response.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The Bordetella pertussis protein pertactin induced type-specific antibodies. "Divergence has been found between Bordetella pertussis vaccine strains and circulating strains. Polymorphism in...

Pneumococcal conjugate vaccine protects children in Brazil.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- The pneumococcal conjugate vaccine reduced mortality from pneumococcal infection in children in Brazil. According to recent research from Brazil, "The distribution of pneumococcal serotypes in...

New data released on plague, strep vaccines.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- ID Biomedical has confirmed that nasal Proteosome-based vaccines protect against pneumonic Plague caused by lethal aerosol infection with virulent Plague bacteria in a mouse model of airborne...

Enterotoxin adjuvant protects mice against respiratory syncytial virus.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Immunization onto shaved skin with a bacterial enterotoxin adjuvant protected mice against respiratory syncytial virus. "This study evaluated the potential of the skin as a non invasive route for...

Naked DNA vaccine cocktail protects against lethal toxoplasmosis in mice.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- A naked DNA vaccine cocktail protected mice against a normally lethal toxoplasmosis challenge. According to recent research published in the journal Vaccine, "BALB/c mice were intramuscularly...

Super-activated interferon-regulatory factors enhance plasmid immunization.
June 4, 2003... 2003 JUN 4 - (NewsRx.com & NewsRx.net) -- Super-activated interferon-regulatory factors can enhance plasmid immunization. According to published research from Canada, "We have been investigating the adjuvant properties of two...

Progenipoietin plus melanoma tumor antigen vaccine stimulates immune response.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Results from a phase I clinical trial indicate that administration of progenipoietin and a vaccine containing melanoma tumor antigens stimulated in a...

Vaccine targeting liver stage of malaria sporozoite elicits T cell response.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A vaccine targeting the liver stage of the malaria sporozoite elicited CD4+ and CD8+ T cell responses, according to a report in the Journal of...

Vaccine research for Alzheimer disease should continue despite setbacks.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Despite the problems that have occurred in vaccine trials for Alzheimer disease, research should continue. "Active or passive immunization against the beta-amyloid peptide (A-beta) has been...

Therapeutic vaccine effective against EBV-associated cancers.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- A therapeutic LMP1 polyepitope vaccine has been developed for Epstein-Barr virus (EBV)-associated Hodgkin's disease and nasopharyngeal carcinoma. According to a study from Australia, "Development...

Single dose of DNA vaccine protects mice against tuberculosis.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- A single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protected mice against a virulent strain of Mycobacterium tuberculosis. "The high...

MMR vaccine and secretin or its receptor may share an antigenic epitope.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- The MMR vaccine and secretin or its receptor may share an antigenic epitope. "In a subgroup of children with autism-spectrum like conditions, symptoms seem to appear as a 'regression' (in normal...

Vaccine to be developed will be directed against multiple HIV antigens.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- BioVex announced that it has signed a letter of intent with the Vaccine Research Center at the National Institutes of Allergy and Infectious Disease, National Institutes of Health, in relation to the...

Botswana to begin trials for AIDS vaccine on humans.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Botswana is scheduled to begin tests on an AIDS vaccine to find out if it is safe when given to healthy adults, officials say. The experimental vaccine, which has already been tested successfully...

Many Americans think an HIV/AIDS vaccine already exists.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Many Americans wrongly believe that a preventive vaccine for HIV/AIDS has already been developed, according to surveys recently conducted by the National Institute of Allergy and Infectious Diseases...

Vaccine induces HIV-specific immune response in chronic infection.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- A controversial vaccine against HIV has been shown to stimulate a critical part of the HIV-specific immune response in chronically infected patients. The small study conducted by researchers at...

Hydroxynorleucine used to introduce amino acid group into carbohydrates.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Hydroxynorleucine as a glycosyl acceptor was an efficient means for introducing amino acid functionality into complex carbohydrates. "A new approach to the synthesis of biologically relevant...

Interleukin 12 is promising adjuvant for cancer vaccination.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Interleukin 12 offers promise as an adjuvant for cancer vaccines. "The clinical development of interleukin 12 (IL-12) as a single agent for systemic cancer therapy has been hindered by its...

Removing CD4+ T cells overcomes suppression of anti-HER2 immune responses.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Elimination of CD4+ T cells may overcome suppression of anti-HER2 immune responses in tumor-bearing hosts. "In this study, we analyzed specific anti-tumor immune responses in tumor-bearing hosts...

Protein structure a target for vaccines and antibiotics.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- A group of researchers from the Scripps Research Institute (TSRI) has solved structures of a bacterial protein called pilin, which is required for infection by pathogens that cause human diseases like...

Vaccine trial launched for previously untreated metastatic disease.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Cancer can be difficult to treat because it tricks the immune system into thinking it's not a threat. Researchers at the Columbia Presbyterian Medical Center at New York-Presbyterian Hospital are...

European patent issued; DNA vaccine research contract granted.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Vical Incorporated (NASDAQ:VICL) announced that European Patent EP0737750, entitled "Expression of Exogenous Polynucleotide Sequences in a Vertebrate," has been granted to Vical. This patent is...

Host absence of CCR5 potentiates dendritic cell vaccination.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- The absence of CCR5 in the host potentiated dendritic cell vaccination. According to a study from the United States, "Previous work has shown that dendritic cells (DCs) express specific chemokine...

Vaccine developer reports 2003 first quarter results.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- VaxGen, Inc., (NASDAQ:VXGN) announced financial results for the first quarter ended March 31, 2003. VaxGen reported an increase in revenue due primarily to its anthrax vaccine development contract...

Genetically engineered virus causes total regression of deadly brain cancer.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Scientists at the Mayo Clinic have evaluated a new genetically engineered measles virus with the ability to fight glioblastoma multiforme, a deadly form of...

DNA priming improves HSV-1 amplicon vector immunogenicity.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - DNA priming improves the immunogenicity of herpes simplex virus-based vectors expressing HIV proteins, researchers in the United States report. "A single...

Hyperglycosylated gp120 mutants may induce broad humoral responses.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Polymorphic forms of the HIV coat protein gp120 may elicit broad humoral responses, researchers in the United States say. "The ability to induce broadly...

Liposome entrapment of hepatitis A virus peptides produces effective vaccine.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Liposome entrapment of multiple antigenic peptide bearing VP1 and VP3 domains of the hepatitis A virus is a robust method for vaccine design. "Multiple antigen peptides (MAP) have been demonstrated...

Hepatitis B vaccination of high-risk adults is cost-effective.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Hepatitis B vaccination of high-risk adults would save lives and money, according to a report in the American Journal of Medicine. According to a study from the United States, "The sequelae of...

Immune transfer through stem cell transplantation effective.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Germany have identified a novel method of inducing immunity to hepatitis B virus (HBV) infection. "Previous data indicate that a transfer of...

CD4+CD25+ T cells are key regulators of immune responses.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- CD4+CD25+ T cells are key regulators of immune responses, and understanding their function may lead to more effective vaccines for autoimmune and inflammatory diseases. According to published...

Light chain variability creates B cell diversity that prevents infections.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections. According to published research from...

Combination vaccine delivers double blow.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- A new vaccine approach that delivers a one-two punch could give the immune system an edge against malaria, AIDS and other exigent diseases in people, Adrian Hill and colleagues report. The...

Elderly adults mount strong immune response to influenza vaccination.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Elderly adults vaccinated against influenza mounted strong, protective immune responses, according to a report in the Journal of Clinical Immunology. According to recent research from Poland, "The...

Influenza vaccine does not cause complications related to asthma or COPD.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- No association was found between conventional influenza vaccination and complications in working-age patients with asthma or chronic obstructive pulmonary disease. Scientists writing in the...

Cryopreservation does not lower dendritic cell immunogenicity.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Cryopreservation of human dendritic cells should not reduce their efficacy in cancer vaccines, researchers in Germany have found. "In the past decade...

Public duped by media over vaccine, says report.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- More than half the British public wrongly believed that medical science was split down the middle about the safety of the measles mumps and rubella (MMR) vaccine according to research by Cardiff...

New type of vaccine developed.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Scientists at the Scripps Research Institute (TSRI) have designed a new way to make vaccines against drugs of abuse that could become a valuable tool for treating addiction by helping the body clear...

Solute binding protein of Streptococcus pneumoniae iron transport found.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- A solute binding protein of Streptococcus pneumoniae iron transport has been identified. According to a study from the United States, "Streptococcus pneumoniae causes considerable morbidity and...

Latent class analysis useful for diagnosis of pneumococcal pneumonia.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Latent class analysis was useful for the diagnosis of pneumococcal pneumonia in adults. According to a study from the United States, "Diagnosis of pneumococcal pneumonia is complicated by the lack...

Group B Streptococcus vaccines under development.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Group B Streptococcus vaccines to prevent infection by capsulate bacteria causing pneumonia are currently being developed. According to recent research published in the journal Current Opinion in...

Pharmacovigilance conference focuses on surveillance of adverse drug reactions.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- The Center for Pharmaceutical Training has announced that its Pharmacovigilance and Drug Safety Summit conference will be held in Philadelphia, Penn., on September 23-24, 2003. According to...

Scientists look for methods to improve vaccinations for infectious diseases.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Oregon Health & Science University (OHSU) researchers are studying new methods to dramatically increase the number of people who can receive vaccinations against smallpox and other deadly diseases. ...

Neurologists play key role in evaluating threat of smallpox attack.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- Neurologists need to play a key role in evaluating the threat posed by a terrorist attack using smallpox. According to a study from the United States, "Smallpox virus, used as a weapon against an...

Mycobacterial Apa protein immunogenic.
June 11, 2003... 2003 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in India have identified a mycobacterial protein that could be used as the basis for a tuberculosis vaccine. "The search to identify...

Dengue virus DNA vaccine protects macaques only in the short term.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Short-term protection against the dengue-2 virus in rhesus macaques was conferred by a DNA vaccine containing a plasmid DNA vector with pre-membrane...

Influenza vaccine with adjuvant more effective in elderly high-risk adults.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Results from a meta-analysis indicate that the influenza vaccine containing MF59 adjuvant is more immunogenic in elderly patients with chronic...

Humanized cocaine-binding antibody characterized.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- A humanized cocaine-binding antibody has been characterized. "The murine immunoglobulin G (IgG) cocaine-binding monoclonal antibody (mAb), GNC92H2, is notable for its exquisite specificity for...

Copaxone vaccine may be effective for treating amyotrophic lateral sclerosis.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- A therapeutic Copaxone vaccine may be effective against amyotrophic lateral sclerosis. According to a study from Germany and Israel, "Therapeutic vaccination with Copaxone (glatiramer acetate,...

Immune response to pneumococcal revaccination in older adults investigated.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- The immune response to pneumococcal revaccination in older adults has been investigated. According to a study from the United States, "As individuals advance in age, the risk of infection,...

Maternal vaccination against nicotine reduces nicotine to the fetal brain.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Maternal vaccination against nicotine reduced nicotine distribution to the fetal brain in rats. "Cigarette smoking during pregnancy is associated with a variety of adverse fetal outcomes. Nicotine...

Allovectin-7 shows promise against metastatic melanoma.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- HLA-B7/beta-2 microglobulin plasmid DNA/lipid complex (Allovectin-7) shows promise for treating metastatic melanoma. "Human leukocyte antigen (HLA)-B7/beta-2 microglobulin plasmid DNA/lipid...

Antigen silencing in melanomas induced by oncostatin M.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Antigen silencing in melanoma tumors is induced by oncostatin M. "We previously reported that antigen expression in melanoma cell lines is down-regulated by proteins secreted by antigen-negative...

CTLA-4 antibody blockade increases tumor immunity in cancer patients.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- A CTLA-4 antibody blockade increased tumor immunity in some previously vaccinated cancer patients. "A large number of cancer-associated gene products evoke immune recognition, but host reactions...

RNA-binding protein L523S is potential therapeutic target for lung cancer.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- L523S, an RNA-binding protein, is a potential therapeutic target for vaccines against lung cancer. According to recent research published in the British Journal of Cancer, "Approaches to...

Tumor-derived ER chaperone grp170 reduces pulmonary metastatic disease.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Immunization with tumor-derived endoplasmic reticulum chaperone grp170 elicited a tumor-specific CD8+ T-cell response and reduced pulmonary metastatic disease. "Glucose-regulated protein (grp) 170...

Xenogenized vaccine cells persist in vivo, preventing tumor attack.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Investigators have released evidence that xenogenized vaccine cells persist in vivo, inducing tumor immunity. "Trioma cell vaccination is a potent new immunotherapeutic strategy for the treatment...

Transforming growth factor beta inhibits action of dendritic cell vaccines.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Transforming growth factor beta inhibited the antigen-presenting functions and antitumor activity of dendritic cell vaccines. "Dendritic cell (DC)-based vaccines have exhibited minimal...

Broad product license acquired for breakthrough DNA-based vaccine.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- In a windfall step that prominently places the company at the center of DNA-based HIV vaccine development, CytRx Corporation (CYTR) announced it has licensed, from the University of Massachusetts...

Review of vaccines for AIDS and Ebola virus infection published.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- A review of vaccine approaches for preventing AIDS and Ebola virus infection has been released. According to recent research published in the journal Virus Research, "Ebola virus and HIV present...

Viral replication reduced in macaques mucosally immunized with SHIV[subscript]89.6.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Evidence has been found for immune-mediated reduction of viral replication in macaques mucosally immunized with inactivated SHIV[subscript]89.6. "Although most HIV-1 infections worldwide result...

Mimotope-based vaccines may be effective hepatitis C virus immunogens.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- Mimotope-based vaccines may be useful as hepatitis C virus immunogens "The hypervariable region 1 (HVR1) of the E2 protein of hepatitis C virus (HCV) is highly heterogeneous in its primary sequence...

HPV vaccines reviewed from basic science to clinical trials.
June 18, 2003... 2003 JUN 18 - (NewsRx.com & NewsRx.net) -- The history of human papillomavirus vaccines, from basic science to clinical trials, has been published in a recent issue of Frontiers in Bioscience. According to researchers in the United States,...