Vaccine Weekly articles from July 2001

Vaccine Weekly archives from July 2001

Peptide Vaccine Ready For Testing In Humans.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A new report in Experimental Biology and Medicine describes the potential for a vaccine against myasthenia gravis in humans, following its success against a...

IL-1 Production Likely Responsible For Pertussis Vaccine Side Effects.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Researchers in Ireland have pinpointed the mechanisms behind some of the neurological side effects seen with the whole-cell pertussis vaccine (Pw). Pw,...

Proof Of Naturally Acquired Immunity Offers Hope For Vaccine.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Infection with the third-largest parasitic killer worldwide, amebiasis, appears to generate natural immunity and thus there is hope for vaccine development,...

Formulation With Three Antigens Exceeds Par In Adult Trials.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Compared with a standard hepatitis B vaccine containing a singular antigen, adult trials of a novel vaccine containing three antigens meets and in some...

Children With Cancer Benefit From Flu Vaccine.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Children who are receiving or have recently received chemotherapy for cancer can benefit from influenza vaccination, according to a new report in Archives...

African Children Hold Clue To Immunity.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- Some children in Africa who show a level of immunity to malaria may provide a clue in the development of an effective vaccine against the disease. A group of researchers from the University of...

Working Group On Civilian Biodefense Warns Tularemia Could Be Threat.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- The Working Group on Civilian Biodefense, an expert panel convened by the Center for Civilian Biodefense Studies at the Johns Hopkins University Bloomberg School of Public Health, says that the...

Increased Patient Survival Follows Treatment For Metastatic Disease.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- Demonstrating new success in cancer immunotherapy, researchers reported that they have increased the survival time of cancer patients using novel therapeutic vaccines. Data show, for the first...

Results Indicate Survival Benefit For Failed Chemo Patients.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- Biomira, Inc. (Nasdaq:BIOM) (TSE:BRA) announced that data from a Phase II clinical trial of Theratope(R) vaccine being tested in metastatic colorectal cancer suggest a survival benefit. The...

105AD7 Vaccination Ineffective For Advanced Disease.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Patients with advanced colorectal cancer have nothing to gain from vaccination with 105AD7, an anti-idiotypic monoclonal antibody that mimics the...

Intra-Spleen DNA Vaccine Stimulates Lymphoid Immune Response.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A DNA vaccine administered to the spleen is capable of stimulating immune responses necessary for protective efficacy, according to a new report in DNA Cell...

Mucosally Immunized Mice Exhibit Immune Memory In Old Age.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Mice primed with Streptococcus mutans protein AgI/II at three months of age show more intense antibody response to subsequent immunization at two years, say...

Manufacturing Agreement Reached For Plasmid DNA-Based Vaccine.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- pAllliance, a strategic alliance between QIAGEN N.V. (Nasdaq: QGENF; Neuer Markt: QIA; Easdaq: QGEN), DSM Biologics, Valentis Inc. (Nasdaq: VLTS), and the Wyeth-Lederle Vaccines (WLV), a business...

FDA Approves First OSHA-Compliant, All-In-One Delivery System.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (NYSE: GSK) announced that it has received U.S. Food and Drug Administration (FDA) approval for Safety Tip-Lok(TM): prefilled Tip-Lok(R) syringes packaged with BD SafetyGlide(TM)...

DNA Vaccine Protects Mice Against Highly Mutational Influenza.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A vaccine that includes plasmid (pME18S-M) containing M1 and M2 genes of influenza A/PR/8/34 offers 70%-80% protection against lethal challenge with...

Phase II Findings Of Therapeutic Vaccine Presented.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- CancerVax Corporation announced that investigators from the John Wayne Cancer Institute (JWCI) in Santa Monica, California, presented clinical results indicating that its therapeutic cancer vaccine...

Cord Blood Antibodies Predict Ear Infection In Infants.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Immunization of pregnant women to boost concentrations of antipolysaccharide pneumococcal antibodies in their infants may reduce the incidence of otitis...

Vaccine Coverage Summarized.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- An article in the June 15, 2001, edition of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Report summarizes the routine polio vaccination coverage, surveillance for...

Immunization With Alum Allows Manipulation Of T-cell Response.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Mice immunized with Porphyromonas gingivalis in alum adjuvant have higher antibody response to P. gingivalis infection than unimmunized mice, say...

Therapeutic Vaccine For Earlier Stage Disease.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- Dendreon Corporation (Nasdaq:DNDN) announced the expansion of its clinical trial program for Provenge(TM), its therapeutic cancer vaccine, with the initiation of a Phase III trial targeting men with...

Vaccine Generates Potent Immune Response.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc. (Nasdaq:PGNX) and Cytogen Corporation (Nasdaq:CYTO) announced that in preclinical studies their experimental prostate cancer vaccine generated a potent dual-immune...

Mouse Survival Prolonged With Dendritic Cell Vaccine.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Mice immunized with Pseudomonas aeruginosa-pulsed dendritic cells (DC) survive significantly longer after pulmonary infection with P. aeruginosa than...

Mucosal Vaccine Generates Immune Response On Par With Live Formulation.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A nasally administered vaccine against Shigella flexneri, the most common cause of dysentery, shows promise against the pathogen in humans and warrants...

Gastrin And Its Receptor Genes Activated At Earliest Stages.(Brief Article)
July 4, 2001... 2001 JUL 4 - (NewsRx.com & NewsRx.net) -- Scientists in collaboration with Aphton Corporation (Nasdaq:APHT) recently published a peer-reviewed article with the new findings that the genes for both the gastrointestinal hormone gastrin and...

Tumor RNA Electroporation May Aid Development.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Belgium have developed a technique for efficiently transfecting malignant genetic material into immune cells, possibly enabling the...

Vaccination With Jeryl-Lynn Strain Works Better For Young Children.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Children younger than five who are vaccinated with the Rubini strain are at significantly greater risk of suffering illness during mumps outbreaks than...

Neutrophil Inhibitory Factor Limits Parasite Fecundity.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Vaccination of hamsters with neutrophil inhibitory factor (NIF), a protein isolated from hookworms of the genus Ancylostoma, does not reduce hookworm...

Community Vaccination Can Be Cost Effective.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Polysaccharide vaccination against serogroup C Neisseria meningitidis may be cost effective under certain conditions, but public health policy makers...

Anti-idiotypic Antibody Vaccine May Prolong Survival.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Women with recurrent ovarian cancer may benefit from vaccination with the murine monoclonal anti-idiotypic antibody ACA125, say researchers working in...

Incorrect Vaccine Regimen Not Uncommon.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Pediatricians should do a double-take when it comes to vaccine regimens for their patients, caution endocrinologists. Incorrect timing of vaccine...

Boosted Immunity Needed For Patients Who Undergo Stem Cell Transplants.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- Researchers have begun two innovative stem cell transplant studies that will look at ways to bolster a patient's immune system in an effort to protect the patient from infection and make the...

Monoclonal Antibody Eradicates Tumors In Animal Models.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- Genmab A/S (CSE:GEN and Neuer Markt:GE9D) announced that its HuMax(TM)-EGFr, a human monoclonal antibody targeting the epidermal growth factor receptor (EGFr), demonstrated potent anti-tumor...

Antigen-Pulsed Dendritic Cells Confer Protection In Mice.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Bone marrow-derived dendritic cells (bmDC), pulsed with herpes simplex virus 2 (HSV-2) antigens completely protected mice from disease and death after...

Can A "Universal" HIV-1 Vaccine Be Developed?(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- Some researchers fear that vaccinations designed to target a single HIV-1 strain wouldn't offer sufficient protection from all versions of the virus. Vaccines based on the viral forms most...

Viral Protein Particles Enable Strain-Specific Antibody Production.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Immunogenic particles made up of HIV proteins can act as a strain-specific vaccine in rhesus macaques, enabling them to produce effective immune responses...

Vaccination Rates In Canadian Long-Term Care Facilities Remain Suboptimal.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Although vaccination rates against influenza and pneumococcal pneumonia in Canadian nursing homes have improved over the past decade, they remain below...

VerticalNews Launch Uses NewsRx Artificial Intelligence Technology.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- NewsRx, the leading provider of life science databases and daily and weekly health news, has leveraged its technology platform to create a new media company, VerticalNews. VerticalNews'...

Supplementary Vaccination Activities Show Limited Impact In Zambia.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- In March 2001, the World Health Organization set a goal for reducing global measles deaths by 50% by 2005. Unfortunately, assessment of supplementary vaccination activities (SVAs) in Zambia...

Numbers Of CD4(+) T Cells Increase In HIV Patients After Antiretroviral Therapy.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- A Georgetown University Medical Center researcher has found that a certain type of CD4(+) T-cell, a type which travels through the lymph nodes, increases in HIV patients after they receive...

Incentive Program Designed To Attract Teenage Mothers To Have Children Immunized.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- New York Weill Cornell Medical Centers uses incentives to encourage teenage mothers to bring their babies in for vaccinations. With the help of grants from two foundations, the Teenage...

Better Physician Counseling Could Lead to Improved Vaccine Coverage.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - If physicians regularly offered education and counseling about the pneumococcal polysaccharide vaccine (PPV), their elderly patients would be more likely...

Modified IL-18 Induces Antitumor Immunity.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The novel cytokine interleukin (IL)-18 can stimulate systemic antitumor effects in mice with renal cell carcinoma, say researchers working in Japan. ...

Lifelong Re-Infection Has Previously-Unrecognized Consequences.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- Respiratory syncytial virus (RSV), and parainfluenza virus - the chief causes of hospitalization for respiratory illness in young children - may be even more menacing than previously believed. ...

Genetic Influences Determine Some Responses To TB Antigens.(Brief Article)
July 11, 2001... 2001 JUL 11 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A study of twins in West Africa has clarified the role of genetics in immune response to Mycobacterium tuberculosis antigens. A. Jepson and colleagues...

GFP-A2/CTB Complexes Could Broaden Horizons Of Cholera Toxin-Based Vaccines.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Researchers in the United States have come up with a novel method of assembling cholera toxin-like complexes in vitro, which could ultimately expand the...

Revaccination Effective In Rare Cases of Hib Vaccine Failure.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Although the conjugated Haemophilus influenzae type b (Hib) vaccine is highly effective against invasive Hib in children, vaccine failures occasionally...

M. Vaccae Immunization Fails To Stop Asthma.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Despite indications on several fronts that exposure to mycobacteria could prevent or treat asthma, a new study from New Zealand has found no such effect....

Vaccination With MUC1 Peptide Is Effective Against Tumors In Vitro.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Human polymorphic epithelial mucin (MUC1) shows efficacy against several MUC1-expressing tumor cell lines and may be ready for further refinement in...

New mAb Vaccine Protects Mice From Human C. Trachomatis Strain.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A new report in Vaccine heralds the arrival of a monoclonal antibody (mAb) vaccine that protects mice against challenge with a human urogenital strain of...

Lactococcus Lactis Fails To Deliver Protection.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The proposed use of Lactococcus lactis as a mucosal adjuvant cannot be supported in the case of Helicobacter pylori vaccination, say researchers working in...

Long-term Care Facilities Should Do More To Encourage Staff Vaccination.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Influenza vaccine coverage is not what it should be among staff at long-term care facilities in Alberta, Canada, and such facilities should take measures...

GM-CSF, IL-6 Boost Efficacy of Autologous Tumor Cell Vaccine.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Mice with established renal cell carcinoma (Renca) tumors achieved complete remission after immunization with an autologous Renca vaccine genetically...

V. Cholerae O139 Antigen Induces Immune Responses In Mice.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The 31-kDa antigen of Vibrio cholerae 0139 can induce protective humoral and cellular immune responses in mice and may one day have an application in...

New Generation Adenovirus Vectors Overcome Preexisting Immunity.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - The latest generation of adenovirus vectors are effective even in animals previously immunized with the same adenovirus serotype, suggesting their efficacy...

Antigen For Vaccine Discovered.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Researchers at The Forsyth Institute, Massachusetts, have discovered a potentially important antigen for a vaccine against dental caries. The antigen, reported in the July 2001 issue of...

Study Ranks Effectiveness Of Common Preventive Medicine.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Childhood vaccinations and anti-smoking counseling for adults are the most effective preventive medicine, says a new study that ranks medical services based on how many lives they save and how much...

First Trinidadian Volunteer Injected With Experimental Combination.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Researchers testing an experimental HIV vaccine have injected the first of 40 volunteers in Trinidad for a study sponsored by a U.S. health agency and the French and U.S. manufacturers. "The...

Risks Mount In The United States.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Concerns about vaccine safety, antibiotic use and resistance, and the importation of infectious diseases have recently intensified in the U.S., health officials said. The officials spoke June...

Health Officials Expect Another Flu Vaccine Delay.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Flu vaccines are expected to arrive late for the upcoming season in the U.S., but the delay should not be as severe as last year's, federal health officials said. The U.S. Centers for Disease...

Clinical Trial Of Cancer Vaccine Initiated.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- MediGene AG (MDG) announced the start of a Phase I/II clinical trial for a vaccine against malignant melanoma. The first step of the therapy against malignant melanoma is the excision of the...

Preclinical And Clinical Advances To Headline At Conference.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Late-breaking advances in engineered antibodies research, in post-genomic high-throughput (HTP) antibody research, in development of novel targets/selection, as well as monoclonal antibody...

Radiolabeled Humanized CD22 Antibody Shows Promise.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Immunomedics, Inc. (IMMU) announced that early clinical trial data of CD22 antibodies for the treatment of non-Hodgkin lymphoma are encouraging. Dr. David M. Goldenberg, Immunomedics,...

Immunity After DTaP-HBV Vaccine Comparable With Natural Infection.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Children who receive the combination vaccine against diphtheria, tetanus, pertussis, and hepatitis B (DTaP-HBV) develop protection against pertussis that...

Siplizumab Safe And Well Tolerated In Clinical Trials.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- MedImmune, Inc. (MEDI) and BioTransplant Incorporated (BTRN) announced results from three clinical trials with siplizumab, showing that the humanized monoclonal antibody is safe and well tolerated...

Three Humanized Antibodies In Clinical Development.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- Protein Design Labs, Inc. (PDLI) announced testing of humanized monoclonal antibodies for the treatment of psoriasis. The company reviewed the three humanized antibodies it is developing for...

Findings For Bovine Trichomoniasis Vaccine May Be Applicable To Humans.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Both systemic and local immunization of cows with an antigen to bovine trichomoniasis protected them from trichomonads and be useful against other sexually...

Varicella Vaccine Does Not Increase Risk of Birth Defects.(Brief Article)
July 25, 2001... 2001 JUL 25 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Women who inadvertently receive the varicella vaccine during or just before pregnancy probably do not have cause for alarm, say researchers working in the...