Vaccine Weekly articles from January 2004

Vaccine Weekly archives from January 2004

Anti-idiotypic antibody fragment effective against candidiasis.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- An engineered synthetic killer anti-idiotypic antibody fragment was effective against experimental mucosal and systemic candidiasis. "Peptides derived from the sequence of a single-chain,...

MIC3 gene of Toxoplasma gondii is potent vaccine candidate.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The MIC3 gene of Toxoplasma gondii is a novel potent vaccine candidate against toxoplasmosis. "Infection with the intracellular protozoan parasite Toxoplasma gondii causes serious public health...

Human antibodies from immunized donors protect against anthrax.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Human antibodies from immunized donors are protective against anthrax toxin in vivo. "A panel of Fabs that neutralize anthrax toxin in vitro was selected from libraries generated from human donors...

Lymphocytic vasculitis associated with anthrax vaccine.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Lymphocytic vasculitis has been associated with the anthrax vaccine. According to published research from the United States, "Anthrax is caused by the spore-forming bacteria Bacillus anthracis. It...

A3 adenosine receptor agonist inhibits colon cancer growth.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The A3 adenosine receptor agonist CF101 inhibits primary colon carcinoma growth and liver metastasis. According to recent research published in the British Journal of Cancer, "Adenosine is a purine...

Cross-reactive H1N1 antibody responses to influenza vaccine reported.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Cross-reactive H1N1 antibody responses to a live attenuated influenza vaccine in children have implication for selection of vaccine strains. According to published research from the United States,...

More positive results reported for Alzhemed.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- At its annual general and special meeting of shareholders, Neurochem, Inc., (NRMX) announced additional positive interim results on cognitive function as measured by the ADAS-cog test in...

U.K. company to work with U.S. Naval Medical Research Center on oral anthrax vaccine.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- U.K.-based biotechnology company Microscience has entered into a cooperative research and development agreement (CRADA) with the Naval Medical Research Center (NMRC). The collaboration will...

Company to expand HDL Therapy development program.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Following a regularly scheduled meeting of the board of directors, Lipid Sciences, Inc., (LIPD) announced the company will now expand the development program for its HDL Therapy platform. This...

Chemotherapy advance reported for women with node-positive early breast cancer.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- A docetaxel (Taxotere)-based regimen reduced the relative risk of death in women with early stage breast cancer by 30% and lowered the relative risk of the cancer returning by 28% when compared to a...

Data from Theratope Vaccine trial presented.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Biomira, Inc., (BIOM, BRA) and Merck KGaA of Darmstadt, Germany, announced that data from the final analysis of their Theratope Vaccine phase III clinical trial in women with metastatic breast cancer...

Tumor growth inhibited by vaccination with Her-2/neu peptides.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Tumor cell growth was inhibited by antibodies induced after vaccination with peptides derived from the extracellular domain of Her-2/neu. According to a study from Austria, "The anti Her-2/neu...

Vaccines for leukemia therapy reviewed.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers have reviewed progress in the development of leukemia vaccines in a recent issue of the journal Acta Haematologica. According to a study from Germany, "Evidence that immunological...

Dendritic cell vaccine to be used in trial for new cancer treatment.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Aastrom Biosciences, Inc., (ASTM) announced the initiation of a phase I clinical trial in collaboration with investigators at Duke University Medical Center (Duke). The clinical trial will evaluate...

Dengue 4 virus glycoprotein induces resistance to Dengue 4 virus.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The carboxy-terminally truncated Dengue 4 virus envelope glycoprotein expressed in Pichia pastoris induced neutralizing antibodies and resistance to Dengue 4 virus challenge in mice. "We have...

NIH begins human Ebola vaccine trial using Biojector 2000.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Bioject Medical Technologies, Inc., (BJCT), a developer of needle-free drug delivery systems, announced that the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious...

Cancer vaccine company reports $10M net loss; provides clinical update.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- CancerVax Corporation (CNVX) announced financial results for the third quarter of 2003. For the 3 months ended September 30, 2003, the company reported a net loss of $10.0 million, as compared to a...

Advantages of rectal vaccination against HIV described.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- AIDS immunization is still to be improved. Russian scientists suggest that rectal vaccination could be the most effective prevention of HIV transmission. The work is supported by the Interdepartmental...

Helicobacter pylori vaccines spiral into the new millennium.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers review progress in the development of Helicobacter pylori vaccines is a recent issue of the journal Digestive and Liver Disease. "This article reviews the current situation regarding...

Hepatitis A vaccine does not promote atherogenesis in murine model.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The hepatitis A vaccine did not promote atherogenesis in a murine model. According to recent research from the United States, "Our laboratory demonstrated that seropositivity to hepatitis A virus...

Immunotherapy company provides update on late-stage adjuvant programs.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Corixa Corp. (CRXA) provided an update on two late stage potential products containing Corixa's MPL adjuvant featured during GlaxoSmithKline's (GSK) recent Research & Development Meeting with investors....

Among high-risk adults, flu shots less likely for blacks than whites.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Adults who are at high risk from flu complications are strongly urged to get an influenza vaccination this year, yet a study shows a racial disparity in the response. In an analysis of data from...

Company reports positive preclinical data against variant influenza strains.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- ID Biomedical reported it has data demonstrating protection against variant strains of influenza. Results from preclinical experiments performed by ID Biomedical scientists and recently published...

Fluvirin influenza vaccine production increased by 50%.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced that it increased production of its Fluvirin flu vaccine for the U.S. 2003-2004 flu season to 38 million doses, approximately 50% more than the previous flu season....

Health plan expands flu vaccine coverage.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Cigna HealthCare announced that it is extending its flu vaccine coverage to include recently U.S. Food and Drug Administration (FDA) approved intranasal influenza vaccines (such as FluMist) for healthy...

Integra syringe maximizes current flu vaccination supply.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- A 10-dose vial of flu vaccine can provide 11 vaccinations when delivered with a Becton, Dickinson and Company (BD) Integra Syringe, BD advises healthcare providers. The syringe is designed with a...

Patient, doctor attitudes can affect rate of flu shots.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Success in immunizing the elderly against flu largely depends on attitudes of both patients and physicians, according to a study that found decreasing vaccination rates before this year's outbreak...

Scientists agonized over choosing less-than-perfect flu vaccine.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Late last winter, a committee of vaccine experts designing this season's flu shot considered their choices. They had two, and both seemed bad. Should they stick with last year's formula, even though...

Scientists warn of coming flu pandemic.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- As bad as this year's flu season is, it hasn't brought the worldwide outbreak known as a pandemic. But experts warn that a pandemic is coming, it's just a question of when. "It's going to happen,"...

Some New Jersey insurers expand coverage to include nasal flu vaccine.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Several insurance companies in New Jersey said they will cover costs for a new nasal flu vaccine during this flu season, according to a report. AmeriHealth, Aetna, Oxford Health Plans, and Horizon...

AmeriHealth to cover FluMist due to vaccine shortage.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- In response to the reported shortage of injectible flu vaccines, AmeriHealth announced that for the remainder of this flu season, the insurer will expand its coverage of flu vaccines to include the...

Leishmania P4 nuclease protects mice against leishmaniasis.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous leishmaniasis. According to recent research published in the journal Infection and...

Data reported in trials of heat shock protein-based cancer vaccines.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Antigenics, Inc., (AGEN) announced updated results from clinical trials of HSPPC-70 (previously referred to as AG-858) and Oncophage (HSPPC-96) personalized cancer vaccines, both of which are based on...

Interim data reported from phase II trial of GVAX vaccine.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Cell Genesys, Inc., (CEGE) reported interim clinical data from a phase II trial of GVAX cancer vaccine for acute myelogenous leukemia (AML). Patients with newly diagnosed leukemia were treated with...

Grant allows research on vaccine for pregnant women to continue.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The Bill & Melinda Gates Foundation has awarded Seattle Biomedical Research Institute a $10 million grant to continue its research in developing a vaccine to prevent malaria in pregnant women. The...

Crossreactive antibodies against Plasmodium protein induced.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers have reported the induction of crossreactive antibodies to Plasmodium falciparum variant protein. "The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1),...

Subtype immunogenicity in Neisseria vaccine not dependent on form.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The relative immunogenicity of PorA subtypes in a multivalent Neisseria meningitidis vaccine was not dependent on presentation form. According to a study from the Netherlands, "The hexavalent...

MyVax Personalized Immunotherapy shows promise in mantle cell lymphoma.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Genitope Corp. (GTOP) announced results of a phase II clinical trial evaluating MyVax Personalized Immunotherapy for the treatment of aggressive non-Hodgkin lymphoma, including mantle cell lymphoma...

Pregnant women request influenza vaccine to protect self and baby.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- With the rising number of influenza cases in the U.S., women who are pregnant or considering becoming pregnant may wonder if the flu vaccine is safe for their unborn babies and themselves. Neil S....

Black men should be screened for prostate cancer at younger age.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- The American Cancer Society (ACS) guideline to begin screening African American men at an earlier age than other races is appropriate, according to a new study in the December 2003 issue of the...

North Carolina health plan to cover cost of FluMist.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- In the wake of shortages of injectable influenza vaccines, Blue Cross and Blue Shield of North Carolina will increase reimbursement to physicians to cover the cost for the FluMist intranasal vaccine for...

Vaccine victims can seek payment.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Emergency response workers who developed health problems from smallpox vaccinations can seek compensation from the U.S. government, the U.S. Health and Human Services Department says. More than...

Company provides update on StaphVAX development program.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Nabi Biopharmaceuticals (NABI) has continued to advance the development of StaphVAX (Staphylococcus aureus polysaccharide conjugate vaccine) and announced updates to its manufacturing and clinical trial...

M protein gene subtypes from invasive group A streptococcus recovered.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers have recovered an array of M protein gene subtypes in invasive group A streptococcus isolates recovered from the active bacterial core surveillance. According to recent research...

Pneumococcal surface adhesin A of Streptococcus pneumoniae analyzed.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Scientists report the results of an analysis of recombinant acylated pneumococcal surface adhesin A of Streptococcus pneumoniae by mass spectrometry in a recent issue of the Archives of Biochemistry and...

Advances in tuberculosis research offer novel vaccine strategy insights.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Advances in antibody-mediated immunity against Mycobacterium tuberculosis have provided insights for developing novel vaccine strategies. "Cell-mediated immunity is considered to be the major...

Report: Additives and preservatives in childhood vaccines are not harmful.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- After reviewing dozens of scientific studies, a leading vaccine expert has concluded that preservatives, additives, and other substances contained in vaccines pose very little risk to children receiving...

Modified adeno-associated virus type 2 circumvents human antibodies.
January 7, 2004... 2004 JAN 7 - (NewsRx.com & NewsRx.net) -- Modified adeno-associated virus type 2 circumvents human antibodies. "The high prevalence of human serum antibodies against adeno-associated virus type 2 (AAV) vectors represents a potential...

Helix 1 peptide elicits antibodies against prion protein in mice.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Helix 1 peptide immunization generates antibodies against the prion protein in wild-type mice. "We present here the development of antibodies against prion protein in BALB/c mice using as antigen...

Severe acute respiratory syndrome -associated coronavirus vaccine shows promise in monkeys.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- A SARS-associated coronavirus vaccine shows promise for eliciting a strong specific immune response in monkeys. According to recent research published in the journal Lancet, "The causative agent...

Flow cytometric assay for responses to anthrax vaccine developed.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Scientists have developed a flow cytometric assay using TNF-alpha detection to determine cellular responses to anthrax vaccine. "This study describes a four-color flow cytometric assay that...

Antigen engineering promotes induction of HIV-neutralizing antibodies.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Antigen engineering can promote the induction of HIV-neutralizing antibodies. According to a study from the United States, "Understanding how neutralizing antibodies recognize HIV could aid the...

Heat shock proteins for immunotherapy of rheumatoid arthritis reviewed.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Researchers review the use of heat shock proteins for immunotherapy of rheumatoid arthritis in a recent issue of Inflammation Research. "Rheumatoid arthritis (RA) is an inflammatory disease that...

recA deletion mutant of M. bovis BCG confers protection.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- A recA deletion mutant of Mycobacterium bovis BCG confers protection equivalent to that of wild-type BCG but shows increased genetic stability. "The widely used vaccine against tuberculosis, BCG,...

FDA issues final order on safety of bacterial vaccines and toxoids.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- To complete the review of the safety and effectiveness of certain bacterial vaccines and toxoids licensed before July 1972, the U.S. Food and Drug Administration (FDA) has issued a final rule and order...

Uptake of polioviral RNA creates antigen by neosynthesis, specific CTL result.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Polioviral RNA can be taken up and an antigen for presentation made by neosynthesis, resulting in antigen-specific cytotoxic lymphocyte production, in an animal model. According to recent research...

Phase III study for kidney cancer vaccine analyzed.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Antigenics Inc. (NASDAQ: AGEN), which is developing personalized immunotherapeutics and treatments for cancers and other diseases, announced that the Data Monitoring Committee (DMC) convened as...

VaxImmune vaccine adjuvant licensed to Chiron.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Coley Pharmaceutical Group, Inc., announced that Chiron Corporation has licensed Coley's proprietary VaxImmune vaccine adjuvant for incorporation into multiple vaccine candidates. Under the terms...

Plasmid DNA activates dendritic cells via toll-like receptor 9.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Vaccination with plasmid DNA activates dendritic cells via toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice. "We analyzed whether the immunobiology of vaccinating plasmid DNA...

Major cause of painful gastroenteritis under study at the Medical College of Georgia.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- It may have made the B list for bioterrorism agents, but Campylobacter jejuni is on the A list when it comes to causes of painful gastroenteritis. Eating inadequately washed and cooked chicken is...

Reengineered dendritic cells readies cytotoxic T cells for select epitopes.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Reengineered dendritic cells readies cytotoxic T cells for select epitopes. According to a study from the United States, "the ability of two plasmid DNA vaccines to stimulate lymphocytes from...

Candidate HIV-1 subtype C DNA vaccine for South Africa characterized.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Researchers have constructed and characterized a candidate HIV-1 subtype C DNA vaccine for South Africa. "A candidate DNA vaccine pTHgagC expressing the immunodeficiency virus-1 (HIV-1) gag gene...

Immunity persists 4 years after hepatitis B vaccination.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Immunity and seroprotection persist four years after a primary vaccination schedule with a Hansenula polymorpha recombinant hepatitis B vaccine. "To evaluate the persistence of the immune response...

Rates on the decline in the United States but not among adults.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Hepatitis B infections have declined by two-thirds in the United States in the past decade, reflecting the routine use of childhood vaccinations against the liver-attacking virus, U.S. health officials...

Heat shock protein 70 gene therapy and hyperthermia boost antitumor immunity.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Heat shock protein 70 gene therapy and hyperthermia boost antitumor immunity. "Heat shock proteins (HSPs) are recognized as significant participants in immune reactions. We previously reported that...

BCBSNC gives North Carolina Health Departments $300,000 for flu vaccines.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Following up on a recent announcement that Blue Cross and Blue Shield of North Carolina (BCBSNC) would cover the cost of the FluMist intranasal influenza vaccine for its members this flu season, the...

Flu treatment options offered.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Fallon Clinic, a community-based physician group practice in central Massachusetts, announced that it has made alternative flu treatments, including the prescription drugs Amantadine and Rimantadine...

Nasal spray flu vaccine may help prevent influenza in healthy children.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- An influenza virus vaccine delivered as a nasal spray, appears to be effective in protecting healthy children against certain strains of influenza, according to a new study. Each winter, influenza...

Aggregate content influences Thl/Th2 response to influenza vaccine.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Aggregate content influences the Thl/Th2 immune response to the influenza vaccine. "During the 2000-2001 season, a newly identified oculo-respiratory syndrome (ORS) was detected across Canada as an...

Health official plays down reports of Central African Republic epidemic.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- The ministry of health in the Central African Republic (CAR) played down reports of a measles epidemic in Banga Yanga commune near the northern town of Bossangoa. "Our services detected some...

ELISA and virus neutralization assay yield same measles antibody titers.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- The enzyme-linked immunosorbent assay and virus neutralization assay yield similar values for measles virus-specific antibody titers. According to recent research from the Netherlands, "We...

BLA submitted for approval of Menactra.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Aventis (AVE) announced the submission of a Biologics Licensing Application (BLA) to the U.S. Food and Drug Administration (FDA) for marketing approval of the use of Menactra Meningococcal (Groups A,...

Disease remains a costly public health threat, says virologist.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Hardly anyone in the U.S. gets rabies anymore. It's a Third World problem. Everyone vaccinates their cats and dogs, and there's a safe, effective - albeit expensive - vaccine for people. Most of us...

Gastrointestinal functions of proteinase-activated receptors reviewed.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- A researcher reviews the gastrointestinal functions of proteinase-activated receptors in a recent issue of the journal Life Sciences. According to a study from Japan, "Proteinase-activated...

Researchers assess putative protein targets derived from the SARS genome.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Researchers have published an assessment of putative protein targets derived from the SARS genome in a recent issue of the journal FEBS Letters. "The ability to rapidly and reliably develop...

CpG-containing oligodeoxynucleotides increase adjuvant effects.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- CpG-containing oligodeoxynucleotides increased effects of immunological adjuvants in rabbits. According to published research from Canada, "The efficacy of oligodeoxymicleotides containing...

Tumor cell vaccines containing nonviral vectors offer cancer prevention.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Tumor cell vaccines containing nonviral vectors offer cancer prevention. "We report that 100% mice survival after tumor challenge is achieved with cytokine-engineered cells employing nonviral...

Cost-utility analysis of vaccine strategies in Switzerland released.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Researchers have published a cost-utility analysis of different vaccine strategies for invasive meningococcal and pneumococcal disease in Switzerland in a recent issue of the journal Vaccine. "We...

Vibrio cholerae toxins activate proinflammatory immune response.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- Vibrio cholerae toxins activate the proinflammatory immune response. According to recent research from the United States, "Vibrio cholerae induces either non-inflammatory diarrhea or inflammatory...

Investigational new drug application to be filed for HIV vaccine.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- CytRx Corporation (CYTR) and Advanced BioScience Laboratories (ABL) announced plans for filing of an Investigational New Drug Application (IND) with the U.S. Food and Drug Administration (FDA) for a...

Incidence of herpes zoster in children reported.
January 21, 2004... 2004 JAN 21 - (NewsRx.com & NewsRx.net) -- An investigator reports the incidence of herpes zoster among children and adolescents in a community with moderate varicella vaccination coverage. According to recent research published in the...

DNA vaccine encoding pertussis toxin S1 subunit induces protection.
January 28, 2004... 2004 JAN 28 - (NewsRx.com & NewsRx.net) -- DNA vaccine encoding pertussis toxin S1 subunit induces protection against Bordetella pertussis in mice. According to a study from Japan, "Pertussis toxin (PT) is the major virulence factor of...

Spore germination provides novel route for antigen delivery.
January 28, 2004... 2004 JAN 28 - (NewsRx.com & NewsRx.net) -- Germination of the spore in the gastrointestinal tract provides a novel route for heterologous antigen delivery. According to recent research from England, "We have evaluated the potential of...

Scientific challenges impeding HIV vaccine development reviewed.
January 28, 2004... 2004 JAN 28 - (NewsRx.com & NewsRx.net) -- The scientific challenges impeding HIV vaccine development were reviewed in a recent issue of the journal HIV Clinical Trials. According to research from the United States, "Most initial work with...