Vaccine Weekly articles from January 1998

Vaccine Weekly archives from January 1998

Recombinant Listeria monocytogenes used as cancer vaccine vehicle.
January 19, 1998... A live recombinant Listeria monocytogenes-based vaccine eliminated tumors generated by oncogenic viral infections. L. monocytogenes is a gram-positive, facultative intracellular bacterium that enters the cytoplasm of infected cells. It can...

All else having failed, India seeks own AIDS vaccine.
January 19, 1998... As a last resort in its losing battle against AIDS, India plans to develop its own AIDS vaccine. Efforts to control India's explosive AIDS epidemic have been too little and too late: 11 years after introduction of HIV into the nation, the World...

Cytokine gene immunotherapy for acute myeloid leukemia.
January 19, 1998... Granulocyte-macrophage colony-stimulating factor (GM-CSF) gene immunotherapy successfully treated established acute myeloid leukemia (AML) in a murine model. Incredible amounts of information have emerged in recent years regarding the...

Gene vaccine protects against Ebola.
January 19, 1998... The world's most feared emerging disease can be prevented by immunization - at least in animals. For the first time, researchers have shown that a vaccine can protect laboratory animals against deadly Ebola virus infection. Repealed attempts...

Parochial attitude limit vaccine potential, journal says.
January 19, 1998... The underuse of vaccines in global health care is the result of short-sighted policies, argue the editors of a major medical journal. On the first page of its first issue for 1998, the editors of Nature Medicine blasted vaccine-development...

Live monkey virus proposed as AIDS vaccine. (simian immunodeficiency virus)
January 19, 1998... Stunning new findings suggest that a live, attenuated monkey virus could protect humans against HIV infection. The provocative results come from a study of rhesus macaque monkeys immunized with live, attenuated simian immunodeficiency virus...

Anti-antibody stimulates anti-HIV immunity.
January 19, 1998... Not even its creators are quite sure how it works, but preclinical studies show that a monoclonal antibody against anti-HIV antibodies increases anti-HIV immunity. The monoclonal antibody (MAb) is called 1F7. It is derived from the sera of...

Vaccine adjuvant research and option agreement extension announced. (Corixa Corp. has extended its research agreement with Pasteur Merieux Connaught)
January 19, 1998... Corixa Corp., Seattle, Washington, announced that it signed an extension of its research agreement with Pasteur Merieux Connaught to study the effectiveness of the protein, Leishmania elongation Initiation Factor (LeIF), as an adjuvant in the...

DNA immunization technology patents licensed. (Dynavax Technologies Corp.'s announcement of license agreement with Vical Inc.)
January 19, 1998... Dynavax Technologies Corp., La Jolla, California, announced a royalty-bearing cross-license agreement with Vical, Inc. that grants each company exclusive, worldwide fights to combine the other firm's patented technology for DNA immunization with...

Exclusive venture formed to develop oral and mucosal vaccines. (Endorex Corp.'s joint venture with Elan Corporation PLC)
January 19, 1998... Endorex Corp., Chicago, Illinois, announced that it has signed a binding letter of intent to establish a joint venture with Elan Corp., plc for the exclusive research, development and commercialization of oral and mucosal prophylactic and...

Patent received for lipid-mediated DNA vaccines. (Vical Inc.)
January 19, 1998... Vical Inc., San Diego, California, announced the issuance of a U.S. patent covering its method of vaccination through direct injection into any tissue of DNA sequences (genes) combined with lipids (fatty substances). Previously issued Vical...