Vaccine Weekly articles from February 2004

Vaccine Weekly archives from February 2004

Tomato parasite shares antigens with Trypanosoma cruzi.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Phytomonas serpens, a tomato parasite, shares antigens with Trypanosoma cruzi that are recognized by human sera and induce protective immunity in mice. According to published research from Brazil,...

IgG antibodies confer sterilizing protection to SHIV-infected macaques.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Transfer of neutralizing IgG antibodies to macaques 6 hours (but not 24 hours) after SHIV infection conferred sterilizing protection. According to a study from the United States, "Passive transfer...

Tumor cells plus adjuvant induced immunity against hepatoma.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Fixed tumor cells in combination with adjuvant induced protective antitumor immunity in a murine hepatoma model. According to recent research published in the journal Cancer Letters, "We previously...

Vaccinia virus DIs expressing SIV gag controls SHIV in monkeys.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Intravenous inoculation of replication-deficient recombinant vaccinia virus DIs expressing simian immunodeficiency virus (SIV) gag controls highly pathogenic SHIV in monkeys. "To be effective, a...

Effectiveness of preventive HPV vaccination reviewed.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers review data on the effectiveness of preventive human papillomavirus (HPV) vaccination in a recent issue of the International Journal of STD and AIDS. According to a study from Finland,...

DNA vaccine elicits strong immune response against malaria sporozoites.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- A novel construct containing functional domains of Plasmodium cynomolgi circumsporozoite (CS) and thrombospondin-related adhesive protein (TRAP) elicited a strong immune response in monkeys. ...

Partnership extended with vaccine research groups.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Targeted Genetics Corporation (TGEN) announced a 3-year extension of its collaboration agreement with the International AIDS Vaccine Initiative (IAVI) and Columbus Children's Research Institute (CCRI)...

Analysis of CD8+ T-cell response after adenovirus vaccination presented.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Scientists provide a detailed analysis of the CD8+ T-cell response following adenovirus vaccination in a recent issue of the Journal of Virology. According to a study from Canada, "We examined CD8+...

Subcontract given to develop anthrax vaccines using nanotechnology.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- BioSante Pharmaceuticals, Inc., (BPA) announced that it has been awarded a subcontract valued at $658,207 for the development of anthrax vaccines for delivery via alternative routes of administration....

$1.1M contract awarded to study counter-bioterrorism vaccine.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Covalent Group, Inc., (CVGR) announced that it has signed a new contract with DynPort Vaccine Company, LLC, (DVC) for a phase I study in the development of a recombinant vaccine designed to provide...

Alliance to develop, commercialize influenza vaccines.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Aventis (AVE) and Crucell N.V. (CRXL) announced that they have entered into a strategic agreement to further develop and commercialize novel influenza vaccine products based on Crucell's proprietary...

Scabies mites use novel immune evasion strategy.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers describe a novel immune evasion strategy in the scabies mite Sarcoptes scabiei in a recent issue of the Journal of Investigative Dermatology. "Parasitic infestation of the skin by the...

Federal government report illustrates current diphtheria risks.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- According to the January 9 issue of the U.S. Centers for Disease Control and Prevention's (CDC) Morbidity & Mortality Weekly Report (MMWR), a recent case of fatal diphtheria was diagnosed in a U.S....

Leading AIDS experts criticize U.S.-sponsored HIV vaccine trial in Thailand.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Several national AIDS experts criticized a U.S. government-sponsored clinical research trial of an AIDS vaccine in Thailand in a recent journal report. The 22 researchers said that there are no...

Company to transfer S. pneumoniae patent portfolio to Aventis.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Genome Therapeutics Corp. (GENE) and Aventis (AVE) have agreed to the sale of Genome Therapeutics' pending patent applications relating to the organism Streptococcus pneumoniae (S. pneumoniae) to...

Hepatitis C glycoprotein expression leads to cryptic intron excision.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Expression of unmodified hepatitis C virus envelope glycoprotein-coding sequences leads to cryptic intron excision and cell surface expression of E1/E2 heterodimers comprising full-length and partially...

CDC study: Flu shot doesn't fend off related illnesses.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- This season's flu vaccine offers little or no protection against flu-like illnesses, according to a U.S. study. The study of 1818 Colorado hospital workers who received flu shots found that only...

Mistrust and fears of risk keep elderly from influenza vaccination.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Fears of potential risk and mistrust of the medical system keep elderly people from obtaining influenza vaccination. "Influenza and its related illnesses remain a major cause of preventable...

Myocardial infarction reported after influenza vaccination.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers review adverse effects occurring after influenza vaccination in a recent issue of Zeitschrift Fur Kardiologie. According to research from Germany, "Influenza is a common disease in the...

Leishmania donovani with BCG protects against leishmaniasis.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Autoclaved Leishmania donovani with BCG has prophylactic potential against experimental visceral leishmaniasis. According to a study from India, "The prophylactic efficacy of autoclaved Leishmania...

Leishmania lesions affect nasal mucosa in rhesus monkey model.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Scientists describe the Leishmania chronic granulomatous cutaneous lesions that affect the nasal mucosa in a rhesus monkey model. "The present studies on infections with Leishmania (Viannia)...

Aotus model for Plasmodium vivax research reviewed.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- A re3searcher has reviewed the Aotus model for research into Plasmodium vivax infection. "The Aotus model for vivax malaria is extremely useful both as a source of living parasites in non-endemic...

Vaccines based on Plasmodium vivax Sal I strains show promise.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Malaria vaccines based on Plasmodium vivax Sal I strains show promise in animal models. "We have previously demonstrated that mouse antisera against yeast-produced recombinant forms of the ookinete...

B. pertussis toxin induces T-cell responses against melanoma.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes. "The adenylate cyclase (CyaA) of Bordetella...

Vaccine company gets broad patent coverage for its core technology platform.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Juvaris BioTherapeutics, Inc., has received notice of allowance from the U.S. Patent Office covering its core technology platform. The company is focused on the development of a new generation of...

Pan-pestivirus PCR primers cross-react with poliovirus genome.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers report that pan-pestivirus PCR primers cross-react with the poliovirus genome. According to recent research from Slovakia and the U.K., "When several human vaccines were tested for...

NIAID awards $12.95 million for biodefense contract.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- NovaScreen Biosciences Corp. has been awarded a 5-year, $12.95 million contract by the National Institute of Allergy and Infectious Diseases (NIAID), a part of the U.S. National Institutes of Health...

Vaccine elicits immune response against respiratory syncytial virus.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- Mucosal delivery of fusion glycoprotein with a CpG oligodeoxynucleotide adjuvant elicited a significant immune response to respiratory syncytial virus infection. According to a study from the United...

U.S. National Committee recommends strengthening vaccine supply.
February 4, 2004... 2004 FEB 4 - (NewsRx.com & NewsRx.net) -- The National Vaccine Advisory Committee in the United States recommends strengthening the nation's vaccine supply. According to a study from the United States, "Between late 2000 and the spring of...

RANK-L gene improves the T cell immune response to infectious agents.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Scientists describe a potent adjuvant effect of ligand to receptor activator of the NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination. ...

Allogeneic melanoma tumor cell lysate vaccine benefits patients.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- The allogeneic melanoma tumor cell lysate vaccine Melacine appears to benefit patients in clinical trials. "The identification of proteins and carbohydrates associated with melanoma led to...

HEV-neutralizing antibodies recognize antigen of ORF2 protein vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Monoclonal antibodies that neutralize hepatitis E virus (HEV) recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine. According to recent research published in the journal...

Vaccines for cervical cancer reviewed.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers have reviewed the information on vaccines for cervical cancer in a recent issue of the Cancer Journal. "Human papillomaviruses (HPVs) are responsible for the nearly 450,000 cervical...

DNA vaccine more effective against rabies than culture-derived vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- A single injection of DNA vaccine is as effective against postexposure rabies as five injections of cell culture-derived vaccine. "Two rabies post-exposure therapies were comparatively evaluated:...

Vaccine adjuvant vector, CTA1-DD/ISCOM, designed.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- A scientists reports the rational design of a vaccine adjuvant vector, CTA1-DD/ISCOM, in a recent issue of the journal Cellular Microbiology. According to a study from Sweden, "Mucosally active...

Man accused of falsely telling woman he gave her AIDS.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- An Erie, Pennsylvania, man has been charged with terroristic threats for falsely telling a woman that he gave her AIDS, police said. Richard Forness, Jr., 22, of Erie, was also charged with...

Thailand rejects criticism of AIDS vaccine trial.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Thailand dismissed criticism by American HIV researchers that a massive test of a possible AIDS vaccine on thousands of healthy Thais would fail, saying the U.S.-funded trial still has hopes of...

AIDS activists fight for more affordable drugs.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Thailand activists on January 17, 2004 urged AIDS sufferers and their supporters worldwide to use a legal victory against a U.S. pharmaceuticals giant in their fight for cheaper and more available...

Inactivated split influenza vaccine safe in children with asthma.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Inactivated split influenza vaccine is safe in children with stable asthma. "Although annual influenza vaccinations are recommended by many authorities, some doctors may be reluctant to vaccinate...

A-beta single chain Fv antibodies isolated from immune phage library.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Amyloid-beta peptide-specific single chain Fv antibodies have been isolated from an immune phage display library. According to recent research published in the Journal of Neuroimmunology, "A...

Contract signed with Pentagon to supply vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- BioPort Corporation announced that the Lansing-based manufacturer of the world's only U.S. Food and Drug Administration (FDA) licensed anthrax vaccine has entered into a 3-year contract to continue...

Bird flu vaccine not likely for 6 months.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Asia's bird flu virus is resistant to key anti-influenza drugs, and an effective vaccine is probably more than 6 months away, the World Health Organization said, as Indonesia confirmed it had become...

Vietnam last on vaccine list.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Drug company contracts and intellectual property rights are impeding efforts to ensure an outbreak of bird flu in Vietnam does not result in a deadly human pandemic. All the victims so far have...

Company reports on mechanism for immunotherapy cure of prostate cancer.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Generex Biotechnology Corp. (GNBT) announced the recent presentation of a poster at the Keystone Symposium, "Rational Design of Vaccines and Immunotherapies," on a novel cancer vaccination method...

Cancer vaccine delivers antigen to dendritic cells.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers have developed an adenoviral vector cancer vaccine that delivers a tumor-associated antigen/CD40-ligand fusion protein to dendritic cells. "To develop a method to overcome the anergy...

First mass cholera vaccination begins.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Health workers in Mozambique are carrying out the world's first mass vaccination against cholera in an attempt to reduce cases in one of the worst-hit areas, the U.N. health agency said January 14th....

NIH research agreement signed to develop rapid vaccine production system.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- The Dow Chemical Company (DOW) has entered into a 4-year, $5.7 million cooperative research agreement from the U.S. National Institutes of Health (NIH) to apply new technology for rapid development of...

New cancer vaccine program launched.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Aventis Pasteur and Aventis Pharma have joined forces to develop a therapeutic cancer vaccine program at a state-of-the-art cancer vaccine laboratory opened earlier this year in Ontario. The...

Victims of cancer drug dilution scheme to receive checks soon.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Victims of former pharmacist Robert R. Courtney's dilutions of cancer drugs soon will begin receiving restitution checks. Officials of U.S. District Court in Kansas City, Missouri, said January 9,...

Hepatitis delta antigens cause varied immunity in mice.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- DNA vaccines consisting of large and small hepatitis delta antigens cause varied immunity in mice. "Whether the hepatitis delta virus (HDV) DNA vaccine can induce anti-HDV antibodies has been...

Company signs NIH agreement to develop vaccines.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Dow Chemical Co. has announced a 4-year, $5.7 million research agreement with the U.S. National Institutes of Health (NIH) to develop plant-based vaccines that it says will be cheaper and easier to...

Healthy women volunteers sought for final trial phase of herpes vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- The Herpevac Trial for Women, conducted by the U.S. National Institute of Allergy and Infectious Diseases, GlaxoSmithKline Biologicals, and numerous research sites, is seeking healthy women ages 18-30...

Multispecific mucosal cytotoxic T cells fail to control SIVmac239.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239. According to published...

Two-dose hepatitis A vaccine effective in Thai children.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- A two-dose hepatitis A vaccine regimen is effective in Thai children. "As fewer children in Thailand are exposed to hepatitis A virus (HAV) and so do not have seroprotective anti-HAV antibodies,...

CHO cell clones expressing hepatitis B surface protein screened.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Scientists have developed a screening method for Chinese hamster ovary (CHO) cell clones expressing histidine-tagged major S hepatitis B surface protein using a semi-quantitative PCR protocol. ...

Hepatitis vaccine collaboration signed.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced a new collaboration agreement with CSL Limited, an Australian-based pharmaceutical company, to develop a therapeutic hepatitis C vaccine. Under the terms of the...

Hepatitis C virus NS4 uses subversive tactics to thwart Th1 response.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus NS4 uses subversive tactics to thwart Th1 response. According to recent research published in the European Journal of Immunology, "the majority of hepatitis C virus (HCV)...

Pathway for cell-associated antigens by dendritic cells characterized.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers have characterized the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells. According to published research from the United States, "Major...

Patent granted for nonlive FluINsure vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- ID Biomedical has received an official "Notice of Allowance" from the United States Patent and Trademark Office with respect to its patent application entitled, "Proteosome Influenza Vaccine." ...

Flu shots last winter not perceived as effective prevention, surveys show.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Two surveys conducted by Harris Interactive suggest that the flu vaccine used to vaccinate people before and during last winter (2002-2003) was not perceived as effective in preventing flu. The...

Flu shots questioned in study of healthcare workers.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- This season's flu vaccine offers little or no protection against flu-like illnesses, according to a United States government study released January 15, 2004. The study of 1,818 Colorado hospital...

Trends in antimalarial drug deployment in sub-Saharan Africa reported.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers report the trends in antimalarial drug deployment in sub-Saharan Africa in a recent issue of the Journal of Experimental Biology. According to published research from the United States,...

Canvaxin therapeutic polyvalent vaccine shows promise against melanoma.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- The Canvaxin therapeutic polyvalent vaccine shows promise against melanoma. According to a study from the United States, "As yet there are no Food and Drug Administration-approved cancer vaccines...

Melanoma vaccines evaluated by monitoring of tumor-specific T cells.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers have evaluated melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. "Immunotherapy of melanoma is aimed to mobilize cytolytic CD8+ T...

Company acquires technology from Fraunhofer Center.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Integrated BioPharma (INB) has acquired intellectual property developed by the Center for Molecular Biotechnology (CMB) of Fraunhofer USA, Inc. The agreement covers exclusive rights to proprietary...

14-3-3 Protein is key molecule in parasites as in other organisms.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- The 14-3-3 protein is a key molecule in parasites as it is in other organisms. "The 14-3-3 proteins represent a family of widely expressed approximately 30-kDa acidic proteins acting as...

Nigerian state upholds ban on polio vaccinations.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Officials of a heavily Islamic northern Nigerian state said they wouldn't lift a ban on polio immunizations, after local tests failed to assuage fundamentalists' fears that the doses contain...

WHO considers rapid response to halt polio spread in Africa.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- With polio continuing to spread in Africa, the World Health Organization (WHO) is preparing to shore up its effort to wipe out the devastating disease worldwide, an official said January 14, 2004. ...

IL-10 regulates immune responses induced by schistosome vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine. According to recent research from England, "Radiation-attenuated (RA) schistosomes...

Smallpox vaccines to be delivered to CDC.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Acambis plc (ACAM) announced an update on its smallpox vaccine program. At the time of its third quarter results announcement in November 2003, Acambis provided an update on the contract with the...

Researchers map pneumococcal surface protein A of strain Rx1.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers have performed epitope mapping of pneumococcal surface protein A of strain Rx1 using monoclonal antibodies and molecular structure modeling. "Pneumococcal surface protein A (PspA) is an...

Plans underway to launch U.S. study of tuberculosis vaccine.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Corixa Corp. (CRXA), a developer of immunotherapeutics, and GlaxoSmithKline Biologicals (GSK Bio), a developer of vaccines and biologicals, announced that the U.S. Food and Drug Administration (FDA) is...

Bacterial spores as heat stable vaccine vehicles reviewed.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Researchers review bacterial spores as heat-stable vaccine vehicles. According to published research from England, "Recently, the first use of bacterial spores as vaccine vehicles was reported,...

Infant develops Kawasaki disease after hepatitis B vaccination.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- An infant developed Kawasaki disease after hepatitis B vaccination. "The known association between hepatitis B and vasculitis has been reported in rare cases in adults after hepatitis B...

Plant-based vaccines to be developed by Dow.
February 11, 2004... 2004 FEB 11 - (NewsRx.com & NewsRx.net) -- Dow Chemical Co. announced a 4-year, $5.7 million research agreement with the U.S. National Institutes of Health to develop plant-based vaccines that it says will be cheaper and easier to produce than...

Plant-produced colorectal cancer antigen developed.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers have developed a plant-derived colorectal cancer antigen. According to recent research from the United States, "Cancer vaccination has become an important focus of oncology in recent...

Poxvirus used for delivery of stimulatory molecules to melanoma tumors.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Poxvirus vaccines are being used for local delivery of costimulatory molecules to melanoma tumors. "The development of vaccines for melanoma has been accelerated by the identification of...

Broadly cross-reactive HIV-neutralizing antibody Fab identified.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers have identified a broadly cross-reactive HIV-neutralizing human monoclonal antibody Fab by sequential antigen panning of a phage display library. "Identification of broadly...

HBsAg variants break tolerance in hepatitis B surface antigen mice.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Vaccination with cross-reactive, natural HBsAg variants breaks tolerance in hepatitis B surface antigen (HBsAg) transgenic mice. "Processing exogenous hepatitis B surface antigen (HBsAg) of the...

Arginine-glysine-aspartate motif enhances immunogenicity of antigens.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- The arginine-glysine-aspartate (RGD) motif enhances immunogenicity and adjuvanicity of peptide antigens following intranasal immunization. "The use of peptides for various aspects of medical...

T cells recognize epitopes of Mycobacterium tuberculosis antigen.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Human CD8+ T cells recognize epitopes of the 28-kDa hemolysin and the 38-kDa antigen of Mycobacterium tuberculosis. According to recent research from the United States, "Mycobacterium tuberculosis...

Patient enrollment completed in HIV vaccine trial.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN) announced that it has completed patient enrollment in the phase I/II therapeutic HIV vaccine trial of its EP HIV-1090 vaccine candidate. All 10 patients in the fourth and...

Alliance formed to support Alzheimer disease synthetic vaccine program.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- Neurochem Inc. (NRMX) announced that the company is advancing its efforts to prevent and treat Alzheimer disease (AD) by forging a strategic alliance with the National Research Council of Canada's...

Anthrax vaccine candidate receives fast track designation.
February 18, 2004... 2004 FEB 18 - (NewsRx.com & NewsRx.net) -- VaxGen, Inc., (VXGN) announced that the U.S. Food and Drug Administration (FDA) has granted a Fast Track designation to the company's anthrax vaccine candidate, rPA102. The Fast Track designation...