Vaccine Weekly articles from February 2001

Vaccine Weekly archives from February 2001

Anti-Idiotypic Humoral Responses Induced by T-Cell Vaccination.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Humans can respond to T-cell vaccination with anti-idiotypic antibody (Ab) responses, neurologists report. "Immunization with irradiated...

New Culture System Allows Long-Term Replication of Hepatitis C Virus RNA.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - Sonia Nichols, staff medical writer -- Hepatitis C virus (HCV), with its many genotypes, is complicated to culture in vitro, thus the difficulty with developing a vaccine for this infection in...

Killed Vaccine Deemed Protective in Clinical Trial.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from Colombia, a population-based trial of a killed Leishmania amazonensis vaccine should be initiated based on the results of...

Autologous T Lymphocytes Specifically Recognize Leukemic B Cells.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from Sweden, the spontaneous immunity found in some chronic lymphocytic leukemia (CLL) patients could be harnessed in a vaccine....

Anti-Glycosylphosphatidylinositol Antibodies are Protective.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Study results indicate anti-glycosylphosphatidylinositols (GPI) antibodies protect against clinical signs of infection. "Induction of...

Influenza Vaccination Reduces Risk of Recurrence.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Reducing the incidence of upper respiratory infection may reduce the risk of recurrent heart attack. "Numerous studies have suggested that...

Multidrug-Resistance On the Rise in the United States.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to recent research from the U.S. Centers for Disease Control and Prevention (CDC), multidrug-resistant strains of Streptococcus pneumoniae...

Systemic and Mucosal Immunizations Induce Protective Immune Responses.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Vaccines against Streptococcus pyogenes have been evaluated in an animal model. "The purpose of this study was to examine the suitability of...

Antigen May be Possible Vaccine Candidate.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from England, a major secreted mycobacterial antigen (Ag) may have potential as a candidate vaccine against tuberculosis. ...

Auxotrophic Mutants Evaluated as Vaccine Candidates.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Researchers in England report that disruption of genes responsible for virulence of Mycobacterium tuberculosis may result in mutants useful as vaccine...

Special Vaccines Could Prevent Insulin-Dependent Diabetes.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- Results of a University of North Carolina at Chapel Hill (UNC-CH) medical study suggest that vaccines can be made using plasmid DNA that would inhibit development of insulin-dependent diabetes, a...

Neutralizing Antibodies Against DPT Induced by Recombinant BCG.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Researchers in Brazil, seeking a new vaccine against diphtheria, pertussis, and tetanus (DPT), put a mutant twist on the old and reliable bacillus...

DNA Immunization Induces Protective Immunity Against Plasmodium falciparum.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Can a DNA vaccine against malaria work? Researchers in France say yes. "DNA-based immunization of mice by Plasmodium falciparum liver-stage...

Study Shows HIV Can Mutate to Attack Human Protective Cells.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- A study conducted by researchers with the Children's Hospital, Columbus, Ohio, suggests that in the advanced stages of HIV, the virus can change its structure in an affected person to a form that...

Oral Vaccination with Mycobacterial Hsp65 Successful in Rat Model.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Oral mycobacterial heat-shock protein 65 (Hsp65) therapy for autoimmune diseases was evaluated by researchers in The Netherlands. "Oral...

Prime-Boost Regimens Enhance DNA Vaccine Efficacy.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Knowing when, how much, and how often helped researchers in England improve the immunogenicity and efficacy of a DNA vaccine against Mycobacterium...

T-Cell Expression Cloning Used to Create Novel Vaccine.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from the United States, advances in technology are facilitating the development of novel and effective vaccines against...

Beta Peptide Vaccine Prevents Memory Loss in Animal Model.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- An amyloid-beta peptide (AB) vaccine was successful in two different mouse models of Alzheimer's disease, researchers in the United States reported....

Dendritic Cell Vaccine Study Shows Promise in Helping Immune System Combat Cancer.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- Scientists at the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center, Los Angeles, California, have found that a dendritic cell "vaccine" was able to elicit a systemic immune...

DNA Immunization with Ras Oncogene Peptide Elicits T-Cell Responses.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Researchers in the United States have discovered a ras oncogene peptide with anticancer potential. "Mutations in ras proto oncogenes are commonly...

Two Ligands Elicit Similar Cytotoxic T-Lymphocyte Responses.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- According to a study from the United States, two CD28 ligands, B7-1 and B7-2, are functionally equivalent at stimulating plasmid DNA-vaccine-elicited...

Mice Inoculated with Hepatitis B Tagged Microspheres Show Good Immune Response.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - Sonia Nichols, staff medical writer -- Tiny microspheres embedded with hepatitis B surface antigen (HBsAg) may comprise the next generation of drug delivery systems for hepatitis B vaccines, if...

Adoptive Transfer Reduces Gastritis Complications.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- - by Michelle Marble, staff medical writer -- Adoptive transfer of splenocytes may effect cure of Helicobacter pylori without gastritis complications, suggest researchers. "Vaccination...

Vaccine for MMR Supported By Leading Health Organizations.(Brief Article)
February 14, 2001... 2001 FEB 14 - (NewsRx.com & NewsRx.net) -- Britain's leading health organizations supported the use of the triple vaccine given to young children to protect them against measles, mumps, and rubella (MMR). The Royal College of Nursing...

Revaccination May Result in Reduced Antibody Response.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from England, repeated immunization using meningococcal polysaccharide vaccines may actually reduce antibody response. ...

Immunization Schedule Protects Burn Patients.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from South Korea, burn patients will benefit from a three-dose vaccine schedule to protect against Pseudomonas aeruginosa. "The...

Recombinant Vaccinia Virus Vaccine Stimulates Protective Immune Responses.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in China have developed a malaria vaccine candidate appropriate for clinical trials. "We constructed a live recombinant vaccinia virus...

Chronic Stress Modulates Adult Immune Responses.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from the United States, adults with chronic stress do not maintain long-term immunity after vaccinations. "Influenza and...

Growth-Factor-Based Vaccine Abrogates Angiogenesis and Tumor Formation.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in the United States hope that one day a simple vaccine may help treat certain cancers. "Basic fibroblast growth factor (FGF-2) is an...

Shiga Toxin/Peptide Vaccine Elicits Cytotoxic T-Lymphocyte Responses.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in France have developed a cancer vaccine that works without an adjuvant. "Immunization with peptide or recombinant proteins generally...

Vaccination Protects Adult Community.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in Sweden conducted a study to see if adult vaccination could be used to help stem the tide of a diphtheria epidemic in the former Soviet...

Chimera Vaccine Evaluated.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers in the United States evaluated different vaccine strains to find the best candidate to provide protection against Japanese encephalitis. ...

Treatment Might Include Gene Therapy and Designer Antibiotics.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- Gene therapy to cure hereditary lung disorders, new treatments for asthma, and "designer" antibiotics to eradicate chronic lung infections are among the future advances that might be on the horizon...

Antigenic Specificity of Infected Cells Defined.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- What makes an effective vaccine against Mycobacterium tuberculosis? Researchers in the United States want to know. "Previous studies in murine and...

Aluminum Hydroxide Adjuvant Up-Regulates Accessory Properties of Human Monocytes.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- How aluminum adjuvants affect the immune system was explored by researchers in Sweden. "Aluminum adjuvants are widely used in human vaccines based on...

HLA Class I Polymorphism and Population Genetics Influence Response.(Brief Article)
February 21, 2001... 2001 FEB 21 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- According to a study from the United States, genetic differences in populations influence vaccine efficacy. "Human leukocyte antigen (HLA)...