Vaccine Weekly articles from February 2000

Vaccine Weekly archives from February 2000

Burgeoning Technology Directs Future of Vaccines.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) The regulatory environment is challenged to keep up with technological advancements in order to approve new vaccines, suggested a researcher from the United States. Carlo Russo, from Merck Research...

GMC-SF Not Effective as an Adjuvant for Hepatitis B Vaccine.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Granulocyte macrophage colony-stimulating factor (GM-CF) is not effective as an adjuvant for hepatitis B vaccines, reported a study from the United States. "GM-CF has shown promise as an adjuvant to...

Interference of Antibody Production Found in Combination Vaccine.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- There is an interference of antibody production to hepatitis B surface antigen in a combination hepatitis A/hepatitis B vaccine, researchers from the United States reported. "A randomized trial comparing 3...

Combined A and B Vaccine Found Effective.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- A combined hepatitis A and B vaccine was found to be safe and effective in a group of adolescents participating in a Belgian study. In this open, randomized trial the safety, reactogenicity, and...

Lymphocyte Proliferation Assays May Underestimate Antigen Responsiveness.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Lymphocyte proliferation assays may underestimate antigen responsiveness in HIV infected patients, suggested a study from the United States. "The objective of this study was to examine the relationships...

Idiotypic Vaccination With a Murine Anti-dsDNA Antibody Safe.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Researchers from Switzerland conducted a Phase I study in patients with nonactive systemic lupus erythematosus with nephritis of an idiotypic vaccine made with a murine anti-dsDNA antibody. The researchers...

Vaccine Trials Complicated by Epidemiologic Changes in Disease.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- New meningococcal vaccines are undergoing clinical trials, and changes in the epidemiologic features of meningococcal disease will affect their use. According to N. E. Rosenstein and colleagues at the US...

Strategies for Meningitis Vaccination Evaluated in Africa.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Outbreak vaccination with the meningococcal polysaccharide vaccine would be more cost effective than population wide vaccination in the meningitis belt area of Africa, researchers from the United States...

Vaccine May Provide Protection Against Non-Bacteremic Pneumonia.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Vaccines against Haemophilus influenzae type b (Hib) may protect infants and young children against non-bacteremic pneumonia, according to researchers from the United States. To assess the incidence of...

Targeted Vaccine Strategy Best.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- A study from Ireland suggests that hepatitis A prevention efforts are most cost-effective when a targeted vaccination approach is used. Researcher E. Rajan and colleagues of Dublin's Mater Private Hospital...

Single Protein Purification May Further Vaccine Research.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- A study examining methods of purifying single proteins from Mycobacterium tuberculosis culture may advance the search for an improved tuberculosis vaccine. Culture filtrate from M. tuberculosis contains...

Vaccine Safe and Effective in Postmarketing Evaluation.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- The varicella vaccine was shown to be safe and effective in a postmarketing evaluation, a recent study from the United States found. "The Oka strain of live attenuated varicella virus was licensed for use...

Tyrosine Kinase Receptor is a Potential Angiogenic Target.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- The tyrosine kinase receptor (TEK) is a potential angiogenic target for a cancer vaccine, suggested researchers from the United Kingdom. "Immune therapy of malignant tumors could be achieved by the...

Allo-Immunization Elicits CD8(+) T-Cell Derived Chemokines.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Allo-immunization of pregnant women against spontaneous recurrent abortion elicits resistance to HIV, reported researchers from the United Kingdom. "We assessed the potential for an allogeneic-based...

Enhanced Disease Associated with Strong T-Cell Activation.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Analysis of T- and B-cell responses to candidate vaccines in outbred human populations may be used to guide the development of protective, non-pathogenic vaccines, according to researchers in England. In...

Non-Alum Adjuvant Approved for US Market.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- MF59 is a non-alum adjuvant that has just been approved for vaccine use in the United States, reported Chiron Corporation of California. Maninder S. Hora, representing colleagues from Chiron Corporation,...

Findings Will Help in Developing Safer Vaccine.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Researchers from England reported research findings that will aid the understanding of the appropriate immune response profile against airborne Venezuelan equine encephalitis virus. The live-attenuated...

Vaccine Technology Applied to a Second Cancer Indication.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- Avax Technologies, Inc, announced that its corporate Investigational New Drug (IND) Application for O-Vax, the company's proprietary haptenized autologous cell vaccine (AC Vaccine) for the treatment of...

Preteen Vaccination Week Emphasizes Hepatitis B Shots.(Statistical Data Included)(Brief Article)
February 2, 2000... 2000 FEB 2 - (NewsRx.com) -- California observed Preteen Vaccine Week January 17-23 in an effort to alert families, schools, and health care providers that now is the time for current sixth graders to begin getting their hepatitis B shots...

Cytosine Deaminase/5-Fluorocytosine-Based Vaccination Studied.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Suicide gene-modified tumor cells may work as therapeutic vaccines against liver metastasis from colon carcinoma, suggested recent research from France. "The cytosine deaminase gene of Escherichia coli...

Shots, Not Oral Vaccine, Are Best Safeguard Against Polio.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Children should be given polio shots instead of the oral vaccine to avoid a tiny chance of a polio infection from the oral dose, the US government announced. Last summer (1999), an advisory panel concluded...

Subunit Vaccine Developed.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- A gene encoding a structural protein (VP2) of a local strain (P3009) of infectious bursal disease virus (IBDV) was cloned and expressed using the baculovirus expression system to develop a subunit vaccine...

New Mathematical Model Explains Changing Patterns in Epidemics.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- A simple, new mathematical model enables scientists to predict epidemics of infectious diseases such as measles. A team of researchers from the University of Florida, University of Cambridge in Cambridge,...

Six Mutant HCV Clone Derivatives Identified.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Researchers have constructed 6 mutant derivatives of a previously identified infectious hepatitis C virus clone in an effort to further the development of a hepatitis C vaccine. Hepatitis C virus (HCV)...

Histidine-Rich Glycoprotein May Prevent Disease Formation.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Histidine-rich glycoprotein (HRG) may serve as an important inhibitor for preventing immune complexes (IC) in diseases such as rheumatoid arthritis. Research from the Australian National University...

Costs of Influenza in Children Higher than Previously Thought.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- For years, the influenza vaccine has been available to anyone who wants to receive protection from the yearly drubbing that the flu hands out to thousands of people in the United States. However, because...

Precaution for a Malaria Vaccine.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Competition between multiple species of malaria parasite in one person can work with the host's immune system to keep all the infections in check, essentially creating a cross-species immunity, new research...

Epitope Defined by mAb 2C7 Could Be Vaccine Candidate.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- A Neisseria gonorrhoeae epitope defined by a monoclonal antibody 2C7 may have potential as a vaccine candidate, researchers from Japan reported. "Lipo-oligosaccharides (LOS) produced by Neisseria...

Immune Response to Vaccine Evaluated.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Monoclonal antibodies generated in response to a thymus-independent antigen and a thymus-dependent toxoid group C capsular polysaccharide vaccine against Neisseria meningitidis were analyzed, reported...

Enhanced Production of Recombinant Antigens Possible.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Replacement of low-usage codons enhanced production of recombinant Mycobacterium tuberculosis antigens in Escherichia coli, researchers from the United States reported. "A major obstacle to development of...

Children with Egg Allergy Not at Increased Risk of Severe Reactions to MMR.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Children who are allergic to eggs do not seem to be at greater risk of a severe allergic reaction to the measles, mumps, and rubella (MMR) vaccine. Writing in January 24, 2000, issue of Archives of Disease...

Redirected Measles Virus Hemagglutinin Protein Attacks Cancer Cells.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Redirection of measles virus hemagglutinin protein kills cancerous cells, reported researchers from the United States. "Measles virus (MV) induces a lethal cytopathic effect in infected cells, causing...

DNA Vaccine Induced Mucosal and Systemic Immune Response.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- A SIV DNA vaccine induced mucosal and systemic immune responses, reported researchers from the United States and the United Kingdom. "A major goal in the development of an effective HIV vaccine is the...

Recombinant HEV Vaccine Tested in Monkeys.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- In a pre-clinical study, 2 doses of a recombinant hepatitis E vaccine provided effective and safe protection against the virus in rhesus monkeys. Smithkline Beecham Biologicals has produced a vaccine from...

Discovery of HIV Shedding Patterns and Viral Site Has Implications for AIDS Vaccines, Treatments.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- AIDS researchers at the University of Pittsburgh, Pennsylvania, have found that viral secretion in HIV positive men follows 1 of 3 patterns, which are in turn related to different sources of HIV in the body....

Chronic Stress Reduces Efficacy.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Chronic stress associated with caring for demented spouses can reduce influenza vaccine efficacy in the elderly, reported researchers from the United Kingdom. "Elderly spousal carers of dementia patients...

Antigen Factors Affect T-Cell Response.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Both the type of antigen presenting cell as well as the nature of the antigen affect respiratory syncytial virus, according to researchers working in the United Kingdom. D. Werling and colleagues compared...

HIV(+) Women Pose Setback for AIDS Vaccine.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- The discovery that 6 Kenyan women are infected with the HIV virus could prove a serious setback for an experimental AIDS vaccine, New Scientist magazine said on January 26, 2000. The vaccine, developed by...

Cooperative Agreement for Candidate HIV/AIDS Vaccine Announced.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Avant Immunotherapetics, Inc., announced that it has entered into a Cooperative Research and Development Agreement (CRADA) with the Walter Reed Army Institute of Research (WRAIR) for the use of...

B7.1 Gene Transfer Improves T-Cell Activation.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- B7.1 gene transfer protects T cells from apoptosis and improves their activation, researchers from Germany reported. "Expression of B7 on tumor cells can circumvent T-cell tolerance and lead to the...

No Evidence that Measles Virus Is Implicated in Crohn's Disease.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- The measles virus does not cause Crohn's disease, researchers from Japan report. Controversy has raged over whether there is a potential link between the disease and MMR (measles, mumps, and rubella)...

Collaborative Study Using INJEX Needle-Free Injection System Announced.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Equidyne Corporation announced that its partially-owned Germany based subsidiary, Rosch AG Medizintechnik (Rosch AG), has entered into a collaboration with Bernhard-Nocht-Institute for Tropical Medicine to...

Company Announces 5 New Patents.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Inhale Therapeutic Systems, Inc, announced it has been issued five new patents in the field of powder processing and has successfully defended an opposition to a previously granted European patent covering...

NIH Program Grant Awarded To Develop Innovative HIV Vaccine Strategies.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- The US National Institutes of Health (NIH) has awarded investigators in the Emory University Vaccine Research Center, Atlanta, Georgia, a 5-year program project grant to develop promising new vaccine...

Merck's Two-Dose Hepatitis B Vaccine Approved for Adolescent Use.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Recent US Food and Drug Administration (FDA) approval of a 2-dose regimen of Recombivax HB, Merck & Co, Inc's vaccine to prevent hepatitis B, may help to protect adolescents 11 to 15 years of age against this...

Broad Antibody Development Agreement, Cancer Vaccine Partnership Announced.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Medarex, Inc. and IDM, a privately held European biotechnology company, announced the formation of a collaboration involving the use of Medarex's HuMAb-Mouse(TM) technology for the generation of fully human...

Human Trials Going Well for C. difficile Vaccine.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Peptide Therapeutics Group, plc, announced positive results from a Phase I/II trial of its vaccine against Clostridium difficile associated diarrhea and colitis (CDAD). The results of the trial showed that...

Group Advocates Adopting New Polio Vaccine Schedule.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- A group of parents whose children were affected by vaccine-associated paralytic polio (VAPP) are calling on physicians to stop using oral polio vaccine (OPV) and implement new recommendations for the exclusive...

Infections a Common Trigger for Acute Respiratory Illness.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Respiratory virus infections commonly trigger serious acute respiratory conditions that result in hospitalization of patients with chronic underlying conditions, according to an article in the January 26, 2000...

Company Reports Promising Results on Universal Vaccine Immune Stimulant.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Epimmune Inc. announced the publication of data in The Journal of Immunology showing that constructs composed of Padre(TM), together with carbohydrate antigens, are potent immunogens that elicit strong antibody...

Patent on Dry Powder DNA Formulations Announced.(Brief Article)(Statistical Data Included)
February 9, 2000... 2000 FEB 9 - (NewsRx.com) -- Inhale Therapeutic Systems, Inc, announced it has been issued US patent 5,994,314 for dry powder formulations of deoxyribonucleic acid (DNA) with viral or commonly used lipid vectors. Dry powder DNA...

Scientists Fear Vaccine Virus Could Persist After Eradication Is Achieved.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- The campaign to eradicate polio is one of the great medical success stories. The disease used to kill or paralyze hundreds of thousands of people every year. But since vaccination began in 1955, the virus has...

Sequence Diversity of Plasmodium falciparum Evaluated.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Researchers from Switzerland evaluated the sequence diversity of the merozoite surface protein 1 of Plasmodium falciparum in clinical isolates from the Kilombero District, Tanzania. "Merozoite surface...

Immunogenicity of Rabies Postexposure Booster Injections Evaluated.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- The immunogenicity of rabies postexposure booster injections was evaluated in subjects who had previously received intradermal preexposure vaccination, researchers from Thailand reported. "Preexposure...

ESAT-6 Vaccine Evaluated Against TB.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- The efficacy of the ESAT-6 subunit tuberculosis vaccine was evaluated by researchers at Denmark's Statens Serum Institut. The ESAT-6 antigen from Mycobacterium tuberculosis is a dominant target for...

Dual Administration of HAV and Yellow Fever Vaccines Evaluated.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Researchers from Switzerland evaluated the tolerance and immunogenicity of the simultaneous administration of hepatitis A virus (HAV) and yellow fever vaccines. "The purpose of this study was to evaluate...

Costs and Benefits of Varicella Screening/Vaccination Evaluated.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- In a recent study, researchers from Saudi Arabia conducted a study to demonstrate the costs and benefits of screening and vaccinating varicella-susceptible health care personnel at a general hospital with...

Combination of Antibodies Shown To Block Transmission of HIV-Like Virus Across Mucous Membranes.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- In Africa, where tens of thousands of children infected with the AIDS virus are born each year, a drug or vaccine capable of preventing the virus from passing from mother to infant has the potential to save...

PRO 542 Reduces HIV Viral Load in Children.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Progenics Pharmaceuticals, Inc., San Francisco, California, presented new data on the company's HIV programs at the 7th Conference on Retroviruses and Opportunistic Infections in San Francisco, California....

DNA Vaccine Produces Antibody Responses to Brugia malayi Antigens.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- DNA vaccination produces antibody responses to single and multiple Brugia malayi antigens, reported researchers from the United States. "DNA vaccination is a convenient means of immunizing animals to...

Transforming Growth Factor-(beta) Antisense Used in Murine Model.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Gene therapies using transforming growth factor-(beta) (TGF-(beta)) may be effective approaches in the treatment of bladder cancer, researchers from Taiwan reported. The possibility of inhibiting gene...

Autoimmunity Causes Altered Antibody Responses to Vaccines.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Islet autoimmunity can cause altered antibody responses to vaccination, reported researchers from Italy and Germany. "Type 1 diabetes is suggested to be associated with T helper 1 immune responses to...

Molting Larval Antigens Potential Targets for Vaccine.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Three venom allergen antigen homologues from Onchocerca volvulus have potential as vaccine candidates, researchers from the United States reported. "Within the framework of ongoing studies on the...

Children's Immunization Campaign Launched at World Economic Forum.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- A global alliance of business leaders, philanthropic foundations, development banks, United Nations agencies, and national governments urged the world's economic powerbrokers to view children as the key to...

Prevention Is Key To Curbing Cancer.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Behavior changes, vaccines, and screening for early detection are the best hopes of curbing the cancer epidemic expected to escalate in the coming decades, cancer experts said. "We have much of the...

Cohort of Exposed Prostitutes May Have Mucosal Immunity.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- A small group of HIV resistant female prostitutes remains seronegative, despite frequent exposure to the virus, researchers reported. Rupert Kaul and colleagues studied the mechanisms of HIV resistance...

Enrollment Completed in Phase I Study of CETP Vaccine in Healthy Volunteers.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Avant Immunotherapeutics, Needham, Massachusetts, announced the completion of enrollment in a double-blind placebo controlled, Phase I trial of its CETP vaccine (CETi-1) in 48 adult volunteers. The trial...

Collaboration Aims To Identify Antigens for Vaccine Development.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Argonex, Inc., Charlottesville, Virginia, has entered into a research collaboration with Wyeth-Lederle Vaccines to identify antigens associated with Chlamydia pneumoniae for application in the development of...

A 14-Member Macrolide Antibiotic Has an Adjuvant Effect.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- A 14-member macrolide antibiotic has an adjuvant effect on a DNA vaccine, according to a study from Japan. "Macrolide antibiotics have unique immunomodulatory actions apart from their antimicrobial...

Synthetic Peptide Vaccine Developed.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- United Biomedical, Inc. (UBI), Hauppauge, New York, has developed a synthetic peptide vaccine "p2249f" which evokes potent antibodies effective against a broad range of HIV primary isolates. This is the...

Vaccines Developed for Cancer and Infectious Diseases.(Brief Article)(Statistical Data Included)
February 16, 2000... 2000 FEB 16 - (NewsRx.com) -- Immunomedics, Inc., Morris Plains, New Jersey, announced that it has received notification of a patent allowance by the U.S. Patent and Trademark Office for a new method of vaccination for cancers and...

Antibody-Based Therapies Target Cell Interaction.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Insights into HIV-1/target cell interaction facilitate development of antibody-based therapeutic strategies, reported researchers from the United States. "The push for an effective AIDS vaccine has been...

Specific Vaccines May Target Autoimmune Diseases.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Certain autoimmune disorders may be treatable with vaccines, suggested researchers from Israel. "Copolymer 1 (Cop 1, Copaxone) is a synthetic amino acid copolymer effective in suppression of experimental...

INF-(alpha) Combined with CD80 Transduction Reduces Tumorigenicity.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Interferon-alpha (IFN-(alpha)) gene therapy in combination with CD80 transduction reduced tumorigenicity and growth of established tumor in poorly immunogenic tumor models, reported researchers from the United...

PBL-Derived CTL May Have Prognostic Value.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Peripheral blood lymphocyte (PBL)-derived cytotoxic T lymphocytes (CTL) generated in vitro are indicative of an anti-tumor immune response in vivo, researchers from Germany reported. "Melanoma-specific...

Anti-Idiotype Immune Responses Generated Post-Vaccination in Myeloma Cells.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Anti-idiotype immune responses were generated following inoculation with an idiotype-protein pulsed dendritic cell vaccine in myeloma cells, researchers from Australia reported. "Myeloma cells produce...

Gene Gun-Mediated Vaccine Induces Antitumor Immunity.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- A gene gun-mediated DNA vaccine induced antitumor immunity against human papillomavirus type 16 (HPV-16) E7-expressing murine tumor metastases in the liver and lungs, researchers from the United States...

Vaccination with Plasmid Expressing HPV L1 Elicits Antibodies.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Immunization with DNA capable of expressing human papillomavirus 6 (HPV) L1 protein has potential as an HPV vaccine strategy for humans, suggested research from Japan. "HPV 6 causes benign condylomata. As...

HIV-1 gp140 Protein Has Potential Use in Multivalent Vaccine.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- gp140 protein may be worth evaluating for immunogenicity as a component of a multivalent HIV-1 vaccine, suggested research from the United States. "The few antibodies that can potently neutralize human...

Nasal Spray Vaccine Protects Against Unexpected Flu Strain.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- An experimental nasal spray flu vaccine protected young children against an influenza strain not covered by the vaccine, according to results from the second year of a study supported by the U.S. National...

Nicotine Vaccine Reduces Nicotine Distribution to Brain.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- A vaccine to help reduce peoples dependence on nicotine may be in the not too distant future, suggested researchers from the United States. "Vaccination of animals to elicit drug-specific antibodies, or...

Secretory Immunoglobulin A Stimulates Mucosal and Systemic Immunity.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Secretory immunoglobulin A can be used for vaccine development, researchers from Switzerland reported. "Immune responses taking place in mucosal tissues are typified by secretory immunoglobulin A (S-IgA)...

Counteracting Tumor-Associated Immunosuppression Is Crucial.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- For cancer immunotherapy to be successful, tumor-associated immunosuppression must be counteracted, reported researchers from the United Kingdom and the United States. "A number of obstacles exist to...

GMCSF Administration Enhances DNA Malaria Vaccine in Certain Conditions.(Brief Article)(Statistical Data Included)
February 23, 2000... 2000 FEB 23 - (NewsRx.com) -- Granulocyte-macrophage colony-stimulating factor (GM-CSF) enhanced the antimalarial immune response of a DNA vaccine only when it was admixed and administered concurrently, researchers from the United States...