Vaccine Weekly articles from December 2003

Vaccine Weekly archives from December 2003

Tumoral immune resistance based on tryptophan degradation by enzyme.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers have found evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. According to a study from Belgium, "T lymphocytes undergo...

Attenuated FIV vaccine protects against systemic or mucosal challenge.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- An attenuated FIV vaccine provided protection from an intraclade challenge administered systemically or mucosally. "Feline immunodeficiency virus (FM) infection of domestic cats represents a...

DNA vaccine induces protective capsular polysaccharide antibody response.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- A multi-epitope DNA vaccine encoding a peptide mimic of meningococcal serogroup C capsular polysaccharide induced a protective capsular polysaccharide antibody response. According to a study from...

Protective effect of 6746 SERA peptide against malaria linked to alpha helix.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- The protective effect of 6746 SERA peptide analogues against malaria is associated with short alpha helix formation. "Erythrocyte high activity binding peptides (HABPs) have been identified for the...

Natural antibodies and complement are endogenous adjuvants for vaccines.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses. "CD8+ T cells are essential for long-term, vaccine-induced resistance against intracellular...

Bioterrorism vaccination is contraindicated in some drug-allergic patients.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Bioterrorism vaccination is contraindicated in some drug-allergic patients. According to a study from the United States, "The threat of bioterrorism continues to be a very real one. Regularly, there...

Domestic animals may be bioterrorism targets; broad health, economic damage possible.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Domestic animals may be bioterrorism targets; broad health, economic damage possible. According to a study from France, "after a brief historical introduction, the authors describe a list of...

New vaccine tested in animals may hold hope for patients.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- In new research, scientists show that two dramatically different approaches may be effective in treating or preventing Alzheimer disease. One approach involves development of a vaccine that clears...

Trypanosoma cruzi antigens elicit strong humoral immune response in mice.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Immunization with the cytoplasmic repetitive antigen and flagellar repetitive antigen of Trypanosoma cruzi elicited a strong humoral immune response in mice. According to recent research published...

New TB vaccine shows promise in people with AIDS.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- An innovative vaccine against tuberculosis has shown promise in people with HIV, researchers from Dartmouth Medical School and the National Public Health Institute of Finland report. An...

Candidates for immunization regimens using DNA vaccines described.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Scientists have published a list of candidates for immune modulation and immunization regimens using DNA vaccines in a recent issue of Methods. According to recent research from the United States,...

Heat shock protein-mediated antigen targeting increases DNA vaccine potency.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Secretory heat shock protein-mediated antigen targeting increases DNA vaccine potency. "In an effort to enhance the potency of DNA vaccines, we have developed a new strategy to increase antigen...

Mucosal immunization with DNA vaccines reviewed.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers review mucosal immunization with DNA vaccines in a recent issue of the journal Methods. According to a study from England, "DNA vaccines represent a new approach to the control of...

Technical issues in construction of nucleic acid vaccines reviewed.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers review the technical issues in construction of nucleic acid vaccines in a recent issue of the journal Methods. "Delivery of antigen-encoding genes by nucleic acid vaccine vectors offers...

Midwest research looks at cows to produce vaccines.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Research to help defend against diseases that could be spread by bioterrorists is being carried out in the pastures of northwest Iowa. Calves have been genetically engineered to produce human...

Scientists predict success of biomedical intervention against rapidly evolving organisms.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Viruses, bacteria, eukaryotic parasites, cancer cells, agricultural pests, and other inconvenient animates have the unfortunate feature to escape from selection pressures that are meant to control them....

Biopharma company announces third quarter 2003 financial results.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- GenVec, Inc., (GNVC), a biopharmaceutical company, announced financial results for the third quarter ended September 30, 2003. GenVec reported higher revenues and a lower net loss through the first...

Healthcare products provider reports record third quarter results.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Henry Schein, Inc., (HSIC), the largest provider of healthcare products and services to office-based practitioners in the combined North American and European markets, reported record third quarter...

Oral immunization with Giardia duodenalis protein inhibits shedding of cysts.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Oral immunization of BALB/c mice with Giardia duodenalis recombinant cyst wall protein inhibited the shedding of cysts. "The process of encystation is a key step in the Giardia duodenalis life...

Preclinical development program initiated for new HIV vaccine candidate.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR) has initiated a preclinical development program with IR103, a new vaccine candidate for the prevention and treatment of HIV, the virus that causes AIDS. The...

New study finds universal vaccination would prevent disease and save lives.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- A U.S. hepatitis A immunization policy would prevent a significant number of debilitating cases of the disease and deaths associated with it, according to a new study. Researchers examined the...

Aspergillus niger effective host for virus-like particle production.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Scientists have demonstrated that Aspergillus niger is an effective host for virus-like particle production, using the hepatitis B surface antigen as a model. "The filamentous fungus Aspergillus...

Researchers reveal essential component of immunity to liver-destroying virus.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers at Columbus Children's Research Institute (CCRI) on the campus of Columbus Children's Hospital have identified a key component of protective immunity against the hepatitis C virus, the major...

Report: Influenza drug market sales to reach $2.5 billion in 2012.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Decision Resources, Inc., forecasts that influenza drug market sales will reach $2.5 billion in 2012. According to a new Pharmacor study entitled "Influenza," MedImmune's FluMist and one other...

Present status of antileishmanial vaccines reviewed.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Scientists review the present status of antileishmanial vaccines in a recent issue of Molecular and Cellular Biochemistry. According to published research from India, "The term leishmaniasis refers...

P. falciparum SERA protein peptide analogues protect against malaria.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Plasmodium falciparum SERA protein peptide analogues having short helical regions induce protection against malaria. According to recent research from Colombia, "Three Plasmodium falciparum serine...

Doses of meningococcal C-tetanus toxoid vaccine can be reduced.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- The number of doses of meningococcal C-tetanus toxoid conjugate vaccine can be reduced without loss of immunogenicity in infants. According to a study from England, "It has been previously shown...

Net Force signs letter of intent to acquire Chinese biotech company.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Net Force Systems, Inc., announced that Net Force has entered into a letter of intent to acquire 100% of the issued and outstanding shares of Tangshan Yian Biological Engineering Co., Ltd., through the...

Patent expands adeno-associated virus manufacturing processes and technology.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Targeted Genetics Corporation (TGEN) announced the issuance of an additional patent related to its adeno-associated virus (AAV) vector production technology. U.S. patent #9,180,114, titled...

Canada lab to use monkeys for SARS research.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Eight monkeys at a Winnipeg lab will be infected with the SARS virus as part of a national effort to develop a vaccine for the deadly respiratory disease. The National Microbiology Lab will try to...

Immune memory from vaccination lasts more than 50 years.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Immune memory after smallpox vaccination persists for at least 50 years in immunized people, according to research conducted by scientists at the Emory Vaccine Center and Emory University School of...

CDCP recommends pneumococcal polysaccharide vaccine for adults older than 65.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDCP) recommends pneumococcal polysaccharide vaccination for all adults 65 years and older. ...

Methods for identification of bacterial vaccine candidates reviewed.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Researchers review methods for the identification of bacterial vaccine candidates in a recent issue of the journal Methods. "Pathogenic bacteria still represent a major threat to human health...

First human trial of West Nile vaccine to begin.
December 3, 2003... 2003 DEC 3 - (NewsRx.com & NewsRx.net) -- Acambis (ACAM) announced the start of a phase I trial of its investigational vaccine against West Nile virus, ChimeriVax-West Nile. Since it was first identified in New York in 1999, the West Nile...

Eosinophilic-lymphocytic myocarditis proven after smallpox vaccination.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Researchers have confirmed the occurrence of eosinophilic-lymphocytic myocarditis after smallpox vaccination. "Smallpox is an eradicated viral disease that has re-emerged as a potential...

Role of adjuvants in vaccine immunogenicity reviewed.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- A researcher has reviewed the role and mechanisms of action of adjuvants in vaccine immunogenicity. According to a study from the United States, "Inactivated vaccines require adjuvants to...

Genetic immunization using pDNA-coated nanoparticles detailed.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Detailed methodology on genetic immunization by jet injection of targeted pDNA-coated nanoparticles has been published in a recent issue of the journal Methods. "Genetic immunization strategies...

Chimeric attenuated vaccine protects against Japanese encephalitis.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Results from Phase 2 clinical trials for safety and immunogenicity indicate that a chimeric live, attenuated vaccine was protective against Japanese encephalitis. "ChimeriVax-JE is a live,...

Histone H1 antigen protects against cutaneous leishmaniasis in monkeys.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- A recombinant histone H1 antigen provided protection against cutaneous leishmaniasis in outbred vervet monkeys. "Infection with Leishmania major parasites results in the development of cutaneous...

West Nile/dengue virus vaccine protect monkeys from West Nile virus.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Molecularly engineered live-attenuated chimeric West Nile/dengue virus vaccines protect rhesus monkeys from West Nile virus. According to published research from the United States, "Two...

AIDS vaccine trials begin in South Africa, Switzerland.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The International AIDS Vaccine Initiative (IAVI) has begun human trials in South Africa and Switzerland to test HIVA.MVA, a candidate vaccine to prevent people uninfected with HIV/AIDS from contracting...

Experimental AIDS vaccine didn't stop HIV.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- An experimental AIDS vaccine tested in Thailand on some 2500 drug users failed to protect them from becoming infected with HIV, the vaccine's developer says. The poor results were widely expected...

MAGE-4 peptide recognized by cytolytic T lymphocytes on tumor cells.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- A new MAGE-4 antigenic peptide is recognized by cytolytic T lymphocytes on HLA-A1 tumor cells. "'Cancer-germline' genes such as those of the MAGE family are expressed in many tumors and in male...

Cells can be frozen with minimal loss using high-pressure freezing, planchettes.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Cells can be frozen with minimal loss using high-pressure freezing, planchettes; even parietal and gastric gland cells remain responsive to histamine. "We describe a procedure for high-pressure...

IU Medical School, Merck take shot at vaccinating Kenyan kids.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Half of the children born in sub-Saharan Africa each year do not receive routine vaccinations to protect them from debilitating or deadly diseases. An ambitious venture of the Indiana University (UI)...

Dengue 2 PDK-53 virus used as chimeric carrier for dengue vaccine.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The dengue 2 PDK-53 virus has been used as a chimeric carrier for tetravalent dengue vaccine development. "Attenuation markers of the candidate dengue 2 (D2) PDK-53 vaccine virus are encoded by...

Human trials start on Ebola vaccine.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- A volunteer has received the first human inoculation of an experimental vaccine designed to prevent infection by Ebola, a highly lethal African virus that some officials fear could be used as a weapon...

AIDS vaccine developer reports increased cash due to financing.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN) announced its financial results for the third quarter ended September 30, 2003. During the quarter, cash and cash equivalents increased by $2.2 million to an ending balance...

ESTRASORB maker announces increased third quarter revenue.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Novavax, Inc., (NVAX) announced financial results for the third quarter ended September 30, 2003. Total revenues for the third quarter of 2003 were $4.3 million compared to third-quarter 2002...

New cancer vaccine trial to begin at New York hospital.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The first patient was recently vaccinated at New York University (NYU) Medical Center with a specific cancer vaccine designed to prevent tumor recurrences in patients who have already had a kind of...

Jet injection is amenable to administering adeno-associated virus vector.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Jet injection is amenable to administering adeno-associated virus vector. According to a study from Czech Republic, "the jet-injection technology was used for delivery of recombinant...

Early SHIV control in monkeys causes long-lasting asymptomatic outcomes.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Early control of highly pathogenic simian immunodeficiency virus/human immunodeficiency virus (SHIV) chimeric virus infections in rhesus monkeys usually results in long-lasting asymptomatic clinical...

Microarray profiling of antibody responses against SHIV developed.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Scientists have developed a method of microarray profiling of antibody responses against simian-human immunodeficiency virus (SHIV). According to a study from the United States, "We developed...

New investigational vaccine tested for first time in humans.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- With an estimated 170 million people around the world already infected with hepatitis C, St. Louis University is testing, for the first time in humans, an investigational vaccine that researchers hope...

HCV core protein modulates immune response against HBV surface antigen.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The hepatitis C virus core protein modulates the immune response against the hepatitis B virus surface antigen in mice. According to recent research published in the journal Biochemical and...

Viral hepatitis markers found in a Canadian First Nations Community.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Researchers found viral hepatitis markers in a large percentage of a Canadian First Nations Community. According to recent research from Canada, "Serological markers for hepatitis A (HAV), B...

Human cytomegalovirus pp65 protein acts as an inhibitor of interferon response.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Human cytomegalovirus pp65 protein acts as an inhibitor of interferon response, can block antiviral activity. "The initial interaction of human cytomegalovirus with fibroblasts triggers, and then...

G protein coupled receptors allow manipulation of inflammation in vivo.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Targeting of G protein coupled receptors may allow management of inflammation in vivo using synthetic and natural ligands. "Cyclic AMP elevating Gs protein coupled receptors were considered for a...

Early evidence suggests current flu season could be severe.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- U.S. Department of Health and Human Services Secretary Tommy G. Thompson once again encouraged Americans, particularly those at high risk of serious complications from influenza, to get their flu shot...

Influenza mutants that can evade cytotoxic T cells will be those that spread.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Influenza mutants that can evade cytotoxic T cells will be those that spread. According to a study from the United States, "a frenzied bout of evolution occurs every flu season, as viruses test the...

Number infected in Midwest outbreak may be higher than first reported.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Researchers at Oregon Health & Science University are trying to gain a better understanding of last summer's monkeypox outbreak. The researchers traveled to the Midwest twice during the past few months...

Disseminated B-cell lymphoma in animal model is controlled by [superscript]213Bi-antiCD74.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Disseminated B-cell lymphoma in animal model is reduced, cured by [superscript]213Bi-antiCD74 monoclonal antibody therapy. According to published research from the United States, "a...

Changes in mumps virus gene sequence linked to phenotype variability.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Changes in mumps virus gene sequence is associated with variability in neurovirulent phenotype. "Mumps virus is highly neurotropic and, prior to widespread vaccination programs, was the major...

Tailored antibody enhances biological activity targeting tumor cells.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Tailored antibody enhances biological activity targeting tumor cells. According to a study from the United States, "vascular endothelial growth factor (VEGF) and its receptors have been implicated...

7-Valent pneumococcal conjugate vaccine effective against otitis media.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The efficacy of a 7-valent pneumococcal polysaccharide-meningococcal outer membrane protein complex conjugate vaccine against pneumococcal acute otitis media was similar to that of the present...

Company gets U.S. patent for Alzheimer vaccine.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Mindset BioPharmaceuticals (USA), Inc., announced that the United States Patent and Trademark Office (USPTO) has issued a notice of allowance for claims covering the company's vaccine for Alzheimer...

Patent issued protecting interleukin-9 activity-reducing vaccine technology.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Genaera Corp. (GENR) announced issuance by the United States Patent and Trademark Office of patent number 6,645,486 covering claims for reducing the activity of interleukin-9 (IL-9) comprising...

Nigerian tests show vaccines do not contain harmful hormones.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Polio vaccines used in a recent nationwide vaccination campaign do not contain hormones linked to infertility and sterility, despite persistent fears to the contrary among Nigerian Muslim...

E1-deleted adenoviral vaccine carriers induce antibody responses.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Mucosally delivered E1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice. "E1-deleted adenoviral vectors of the human serotype 5 (AdHu5) and...

Studies describe heart disease following vaccination.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Heart-related complications can occur after the smallpox vaccine, but symptoms are usually mild, according to three studies presented at the American Heart Association's Scientific Sessions 2003 in...

Test may predict adverse reaction to smallpox vaccinations.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- The ability to predict which individuals would respond adversely to smallpox (variola major) vaccination may be possible, according to data presented by Malka Rais, MD, Georgetown University, at the...

Safer smallpox vaccination regimen modeled for HIV-1-infected patients.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Scientists have modeled a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques. According to a study from an international...

BAFF overexpression in lupus may be blockable with decoy receptor, monoclonal.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- In lupus erythematosus, excess BAFF expression may be curbed by treatment with decoy BAFF receptor or with monoclonal antibodies; may stop symptoms. "BAFF, a member of the family of tumor necrosis...

Danish BCG vaccine-induced disease found in HIV-infected children.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Danish bacille Calmette-Guerin (BCG) vaccine-induced disease was found in human immunodeficiency virus-infected children. According to a study from South Africa, "An analysis of isolates of...

Racial and ethnic disparities in immunizations outlined.
December 10, 2003... 2003 DEC 10 - (NewsRx.com & NewsRx.net) -- Researchers have published recommendations for clinicians on the racial and ethnic disparities in immunizations in a recent issue of the journal Family Medicine. According to a researcher in the...

T-cell response against hepatitis C virus optimized.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- T-cell responses against hepatitis C virus E2 optimized by antigen engineering in DNA immunization. "Although DNA immunization is a safe and efficient method for inducing cellular immune...

Complete cross-reactivity found in Toxoplasma gondii isolates.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- An analysis involving 124 isolates of Toxoplasma gondii indicated that complete cross-reactivity means one vaccine is likely to protect against all of the isolates. According to a study from the...

Scientists describe biochemistry of vaccine adjuvants.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- A team of scientists at the Scripps Research Institute (TSRI) has published a paper that explains how adjuvants work in greater biochemical detail than has been known previously. Adjuvants are...

Antibodies to histone-like protein protect against Histoplasma.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- Antibodies to a cell surface histone-like protein protect against Histoplasma capsulatum "A protective role for antibodies has not previously been described for host defense against the pathogenic...

Expression of protein of Plasmodium yoelii protects against malaria.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- Priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8[superscript]+-T-cell epitope from the circumsporozoite protein of Plasmodium...

Immune response to RSV infection linked to nasal antibody responses.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- The inability to evoke a long-lasting protective immune response to respiratory syncytial virus (RSV) infection in mice correlates with ineffective nasal antibody responses. "Long-lasting...

Therapeutic vaccines against infectious diseases face challenges.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- Researchers outline the challenges facing therapeutic vaccines against infectious diseases in a recent issue of Current Opinion in Microbiology. "Therapeutic vaccines against chronic infectious...

Five-year, $1.5 million grant to fight spread of HIV/AIDS and TB in Africa.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- At a time when HIV/AIDS in the developing world has reached epidemic stages, a team of international researchers, led by Ford von Reyn, MD, professor of medicine, Dartmouth Medical School (DMS) and...

Drug resistance linked to location and emm type of Streptococcus.
December 17, 2003... 2003 DEC 17 - (NewsRx.com & NewsRx.net) -- Drug resistance was associated with location and emm type of clinical group A streptococcal isolates from eight basic training military sites. According to recent research from the United States,...