Vaccine Weekly articles from August 2004

Vaccine Weekly archives from August 2004

Antennapedia transduction sequence promotes antitumor immunity.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The Antennapedia transduction sequence promotes antitumor immunity to epicutaneously administered CTL epitopes. According to published research from Canada, "The identification of tumor antigens...

Herpes simplex virus type 2 vaccines under development.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers are getting closer to developing effective herpes simplex virus type 2 vaccines. According to recent research published in the journal Clinical and Diagnostic Laboratory Immunology,...

Sendai virus expressing RSV glycoprotein elicits immune protection.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Recombinant Sendai virus expressing the G glycoprotein of respiratory syncytial virus (RSV) elicits immune protection against RSV. According to a study from the United States, "Although RSV causes...

WNV vaccine shows 100% protection in animal study, company reports.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Hawaii Biotech, Inc., a Hawaii-based biopharmaceutical company, announced that in a second study its West Nile vaccine protected 100% of test animals from both illness and death when challenged with...

Inverted pathogenicity useful for prevention or therapy of disease.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Inverted pathogenicity is finding use for the prevention or therapy of disease. "The term 'inverted pathogenicity' stands for the exploitation of microbial toxins, virulence factors, and cellular...

Novel approach to specific allergy treatment developed.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (RSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity....

U.S. mayors support anthrax vaccine for police, firefighters.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- As the United States military announced plans to expand its soldiers' anthrax and smallpox immunization program, the growing debate about how best to protect America's police and firefighters has also...

Bovine collagen peptide vaccine modulates severity of arthritis.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Vaccination with an immunodominant peptide of bovine type II collagen induces an anti-TCR response, and modulates the onset and severity of collagen-induced arthritis. According to a study from...

Thymosin alpha 1 activates dendritic cells for antifungal resistance.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through Toll-like receptor signaling. "Dendritic cells (DCs) show a remarkable functional plasticity in the recognition of...

Report: Singapore researchers develop gene-based asthma vaccine.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Singapore researchers have developed an asthma vaccine using a dust mite gene, a newspaper reported. Most asthma sufferers in tropical and subtropical countries are allergic to dust mites, the...

Congress OKs bill to create vaccines, antidotes to biological, chemical weapons.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Enough new-generation anthrax vaccine to dose 25 million people: That's first on the U.S. government's shopping list under a massive new program to develop and stockpile antidotes to biological and...

Vaccination with botulinum neurotoxin fragments prevents botulism.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Vaccination with botulinum neurotoxin fragments prevents botulism. "Mice and ducks were subcutaneously immunized with recombinant whole heavy (H) chains of Clostridium botulinum type C and D...

Vaccine targeting cancer-related antigens appears to prolong survival.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers seeking to direct cancer-killing immune cells against the deadliest brain tumors have three new targets that show promise in laboratory studies and in a Phase I patient trial, according to...

Buruli ulcer disease in Cameroon rediscovered.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers have rediscovered Buruli ulcer disease in Cameroon. According to published research from Cameroon and Belgium, "To assess the magnitude of the Buruli ulcer (BU) problem in Cameroon, we...

Biosafety lab expansion, patent issuance and biodefense reagents sale announced.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Commonwealth Biotechnologies, Inc., (NASDAQ: CBTE) announced completion of its new virology biosafety level 3 laboratory within its accredited BSL-3 suite. Construction and fit-out of the new lab...

Alloantigen presentation linked to CTL antigen response.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The duration of alloantigen presentation and avidity of T cell antigen recognition correlate with immunodominance of CTL response to minor histocompatibility antigens. "CD8 T lymphocytes (CTL)...

Autologous lymphoma vaccines induce T cell responses against epitopes.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Autologous lymphoma vaccines induce human T cell responses against multiple, unique epitopes. "The clonotypic surface Ig receptor expressed by malignant B cells, idiotype, is a tumor-specific...

DNA fusion gene vaccines against cancer reviewed.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Investigators review DNA fusion gene vaccines against cancer in a recent issue of Immunological Reviews. "Vaccination against target antigens expressed by cancer cells has now become a realistic...

NY-ESO-1-related HLA A2-restricted epitopes characterized.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers have determined the functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes. According to a study from Australia, "NY-ESO-1, a commonly expressed tumor...

Reduced L-selectin expression identifies tumor-specific type 1 T cells.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Reduced L-selectin (CD62L[superscript]Low) expression identifies tumor-specific type 1 T cells from lymph nodes draining an autologous tumor cell vaccine. "Reduced expression of CD62L can identify...

SSX-2 epitope presented by dendritic cells to CD4+ T cells identified.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists have identified an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells. According to recent research from the United States, "Accumulating evidence supports...

TCR DNA vaccine induces humoral response for lymphoma beta chain.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- A TCR DNA vaccine induced a humoral immunoreaction for the beta chain of T cell lymphoma. According to published research from China, "We exploited the humoral immunoreaction of mice induced by TCR...

Transfection of tumor antigens generates cytotoxic T lymphocytes.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes....

Preschoolers not getting vaccinated on time.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- More than 20% of U.S preschool children lack required immunizations, placing them and their classmates at risk for illness, according to a new study based on the federal National Immunization Survey....

Vaccination policy can drive economic growth, expert says.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Immunization programs can be highly effective tools for promoting economic growth and poverty reduction in developing countries, according to Dr. David Bloom of the Harvard School of Public Health. ...

Microparticles act as carriers to deliver plasmid DNA in vaccines.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Cross-linked microparticles act as carriers for the delivery of plasmid DNA for vaccine development. According to a study from the United States, "Plasmid DNA was directly encapsulated into...

NIH cancels contract for HIV vaccine program.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- NOVAVAX, INC. (NASDAQ:NVAX) announced that the U.S. National Institute of Allergy and Infectious Diseases (NIAID) has cancelled its 5-year contract [NO1-AI-30042] for the development of human...

Ukraine signs joint declaration to combat AIDS.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Facing one of the fastest growing AIDS infection rates in the world, Ukraine joined an international alliance to battle the disease, Ukrainian health officials said. By joining the alliance,...

HIV/AIDS drug users shunned by healthcare providers.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The vast majority of HIV patients in many countries of Asia and Eastern Europe are injecting drug users, and they often lack access to prevention and treatment services because of discrimination and...

$14.2 million NIH contract awarded for pathogen drug and diagnostic development.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc., (NASDAQ:MYGN) announced that it has been awarded a five-year, $14.2 million contract by the U.S. National Institute of Allergy and Infectious Diseases (NIAID). The agreement...

WHO says world has 'failed miserably' in getting AIDS drugs to millions.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The World Health Organization (WHO) said July 13, 2004, the world has "failed miserably" in getting lifesaving drugs to millions afflicted with HIV, and France accused the United States of bullying poor...

Single recombinant anti-RhD IgG prevents RhD immunization.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- A single recombinant anti-RhD IgG prevents RhD immunization. "A single recombinant immunoglobulin G1 (IgG1) anti-RhD antibody (MonoRho) was compared with a currently used polyclonal anti-RhD...

Live and inactivated hepatitis A vaccines induced immunity in children.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Live attenuated and inactivated hepatitis A vaccines induced anti-HAV immune responses in children. "The immunogenicity of a live attenuated HAV vaccine and an inactivated HAV vaccine was compared....

Methods predict hepatitis A vaccination in men who have sex with men.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists have developed methods predictive of hepatitis A vaccination in a sample of men who have sex with men. According to recent research published in the journal Health Education Research,...

Deficit in dendritic cell-T cell interaction crucial in hepatitis B.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- A selective functional deficit in dendritic cell-T cell interactions is a crucial mechanism in chronic hepatitis B virus infection. "A defect in specific T cell immunity has long been assumed to be...

Tumor necrosis factor DNA enhances immune response against herpes.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Tumor necrosis factor (TNF) DNA enhances the immune response in DNA immunization against the herpes simplex virus. "A study was made of the adjuvant effect of the mouse tumor necrosis factor alpha...

DNA microarray format for subtyping human papillomavirus developed.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers have developed a DNA microarray format for detection and subtyping of human papillomavirus. "A new human papillomavirus (HPV) assay using high-density DNA microarrays; is described. An...

Adult immunization in primary care and specialty practices reported.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Investigators report the extent of adult immunization in university-based primary care and specialty practices. "The purpose of this study was to assess vaccination status of adults in primary and...

HSP70 mutants separate antigen delivery from DC stimulation.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- HSP70 peptide binding mutants separate antigen delivery from dendritic cell (DC) stimulation. "Microbial heat shock proteins (HSPs) have been implicated in the induction of both the innate and...

Study to evaluate vaccination methods for most vulnerable in bioterrorist attack.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers at Oregon Health & Science University (OHSU) have been awarded a $10 million program grant to investigate methods for vaccinating those most susceptible to biological attacks or natural...

Global efforts toward AIDS vaccine continue to fall short, according to report.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Global efforts to develop a vaccine to prevent HIV infection and AIDS have intensified over the past few years, yet they continue to fall short of what is likely to be needed to achieve success,...

Program helps care providers increase pediatric influenza vaccination rates.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The U.S. National Foundation for Infectious Diseases (NFID) has launched a new in-practice resource program, Kids Need Flu Vaccine, Too! Influenza vaccination rates are the lowest for any...

CDC recommends resumption of third dose of Prevnar.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The Centers for Disease Control and Prevention (CDC) has issued an updated recommendation that all healthy children under 24 months of age should receive at least 3 doses of Prevnar, Pneumococcal...

$1.4M grant to support development of malaria vaccine.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The Institute for OneWorld Health has received a $1.4 million grant from the Bill & Melinda Gates Foundation to support development of a vaccine for the prevention and treatment of malaria, including...

Plasmodium vivax merozoite surface proteins possess immunogenicity.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Plasmodium vivax merozoite surface protein-9 recombinant proteins expressed in E. coli possess immunogenicity. "Merozoite surface protein-9 of Plasmodium vivax (PvMSP-9) is highly conserved and...

RTS,S+TRAP malaria vaccine shows promise for infant immunization.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- An RTS,S+TRAP malaria vaccine, formulated in the AS02A adjuvant system, appears promising for immunization of infants. According to a study from the United States, "Malaria vaccine RTS,S combined...

Company receives license for new meningococcal B vaccine for New Zealand.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Chiron Corp. (CHIR) has received a license for its new meningococcal B vaccine for New Zealand, MeNZB. Chiron developed the vaccine, in close collaboration with the New Zealand Ministry of Health...

Universal childhood vaccination benefits society.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Universal childhood vaccination provides great value to the community. According to recent research published in the journal Vaccine, "Availability of new vaccines preventing infectious diseases in...

SIGA announces the appointment of Bernard L. Kasten, MD as CEO.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- SIGA Technologies, Inc., (NASDAQ: SIGA) announced the appointment of Bernard L. Kasten, MD, as its chief executive officer. Kasten joins SIGA following eight years at Quest Diagnostics where he was...

Whooping cough making dangerous comeback.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Whooping cough, one of those ancient scourges that infant vaccination was meant to wipe out, is making a dangerous comeback: It turns out the vaccine that babies get starts wearing off by adolescence....

Efficacies of pertussis vaccines against B. parapertussis compared.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists have compared the efficacies of whole cell and acellular pertussis vaccines against Bordetella parapertussis in a mouse model. According to a study from the Netherlands, "Pertussis...

Health groups reinstate recommendation for third dose of pediatric Prevnar.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Public health and physician groups have recommended that healthcare providers increase the number of doses of pneumococcal conjugate vaccine (PCV7, trade name Prevnar) administered to healthy children...

Prevalence of anti-rubella antibodies decline in Polish women.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The prevalence of anti-rubella antibodies has declined in women of childbearing age in Poland. According to a study from Poland, "Congenital rubella is a clinically serious problem, which is due to...

T cells from Salmonella vaccine cause interclonal competition.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- A massive number of antigen-specific CD4 T cells during vaccination with live attenuated Salmonella causes interclonal competition. "The clonal burst size of CD4 T cells is predicted to be less...

Antibody isotype patterns to Schistosoma antigens identified.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists have identified antigen-specific antibody isotype patterns to Schistosoma japonicum recombinant and native antigens in a defined population in Leyte, the Philippines. According to recent...

Features linked to antibody protection against ricin determined.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists have determined the immunological characteristics associated with the protective efficacy of antibodies to ricin. According to published research from the United States, "A/B toxins,...

Immunomodulatory action of mycobacterial secretory proteins reviewed.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists review the immunomodulatory action of mycobacterial secretory proteins in a recent issue of the journal Microbes and Infection. According to a study from India, "The recently discovered...

Protein microspheres elicit immune response against M. tuberculosis.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- A single vaccination with protein microspheres elicits a strong CD8 T-cell-mediated immune response against Mycobacterium tuberculosis antigen Mtb8.4. According to a study from the United States,...

Glycol chitosan improves efficacy of bovine herpesvirus vaccine.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Glycol chitosan improves the efficacy of intranasally administrated replication defective human adenovirus type 5 expressing glycoprotein D of bovine herpesvirus 1. According to published research...

Molecular adjuvants for mucosal immunity reviewed.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers review molecular adjuvants for mucosal immunity in a recent issue of Immunological Reviews. According to a study from the United States, "Mucosal surfaces represent the entry route of a...

Bacterial ghosts are an efficient delivery system for DNA vaccines.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Bacterial ghosts are an efficient delivery system for DNA vaccines. According to a study from Germany, Austria, and Slovakia. "Mass implementation of DNA vaccines is hindered by the requirement of...

Toxin from Bordetella pertussis offers promise for antigen delivery.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The adenylate cyclase toxin from Bordetella pertussis is a novel promising vehicle for antigen delivery to dendritic cells. According to recent research from France, "Bordetella pertussis secretes...

Antigen distribution in mono-valent and combination vaccines reported.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers have determined the distribution of adsorbed antigen in mono-valent and combination vaccines. According to recent research published in the journal Vaccine, "The distribution of...

Bilayer composition affects dendritic cell-liposome interactions.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The bilayer composition affected the interactions of dendritic cells with antigen-containing liposomes. "Vaccine efficacy might be improved by exploiting the potent antigen presenting properties of...

CD70 stimulation promotes strong cytotoxic T cell responses in vivo.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo. "Identification of the signals required for optimal differentiation of naive CD8+ T cells...

Cochrane Vaccines Field develop criteria for vaccine evaluation.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The Cochrane Vaccines Field develop criteria for vaccine evaluation. "The Cochrane Vaccines Field (CVF) is a Cochrane Collaboration entity. The CVF was founded to facilitate the gathering of...

IgG1 suppression occurs with IL-6 overexpression in immunized mice.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Transient suppression of IgG1 occurs with IL-6 overexpression in immunized TCR-transgenic mice. "Helper T cell-derived cytokines play a pivotal role in the production of antigen-specific IgG...

Neonatal dendritic cells deficient in presentation of soluble antigen.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Murine neonatal dendritic cells are deficient in MHC class I cross-presentation of soluble antigen. According to recent research from the United States, "Neonates respond suboptimally to many...

Success of immunization may also be its downfall.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- The success of immunization may also be its downfall. "Successful immunization programs have reduced the burden of a number of infectious diseases on a global scale. Yet, as the fear of sequelae of...

Hospitalization and adverse events temporally linked to immunization.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Immunization is associated with material deprivation, hospitalization, and adverse events. According to recent research published in the journal Vaccine, "We examined hospital admissions for...

Methodological issues arising from reviews of vaccine safety outlined.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists outline the methodological issues arising from systematic reviews of the evidence of safety of vaccines in a recent issue of Vaccine. According to a study from England, "Adaptations to...

Technologies to increase safety of vaccine administration described.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers describe technologies that increase the safety of vaccine administration in a recent issue of Vaccine. According to recent research from Switzerland, "There is an ever-expanding...

Vaccine safety research more important after 11 September 2001.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Research to develop safer vaccines is more important after the events of 11 September 2001. "As immunization programs world-wide 'mature' with high vaccine coverage and near elimination of...

Vaccine surveillance helps evaluate safety of vaccines.
August 4, 2004... 2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Vaccine surveillance helps evaluate the safety of vaccines. "In this article we discuss some of the most widely used methods of the routine vaccine safety surveillance. The main problems inherently...

Antibodies against anthrax protective antigen promote macrophage death.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- A subset of monoclonal antibodies against anthrax protective antigen increases lethal toxin-mediated killing of murine macrophages. "We investigated the ability of using monoclonal antibodies...

IL-12-engineered allogeneic cell vaccine prevents breast cancer.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- An interleukin 12-engineered allogeneic cell vaccine prevents HER-2/neu transgenic breast cancer. According to recent research published in the journal Cancer Research, "This study evaluated the...

Antibodies against MAEBL ligand domains inhibit sporozoite development.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Antibodies against MAEBL ligand domains M1 and M2 inhibit sporozoite development in vitro. "MAEBL is a type 1 membrane protein that is implicated in the merozoite invasion of erythrocytes and...

Responses to antigen of Plasmodium linked to malaria immunity.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Responses to the rhoptry-associated membrane antigen of Plasmodium falciparum are associated with immunity to malaria infection. "Rhoptry proteins participate in the invasion of red blood cells by...

MVA ROP2 vaccinia virus is vaccine candidate for toxoplasmosis.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Recombinant MVA ROP2 vaccinia virus is a vaccine candidate for toxoplasmosis. According to a study from Mexico, "Toxoplasma gondii is the etiological agent of toxoplasmosis and is the most frequent...

Protective T-cell epitope in p15[superscript]gag of leukemia virus identified.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Scientists have identified a protective CD4+ T-Cell epitope in p15[superscript]gag of Friend murine leukemia virus. "Recent studies have demonstrated an essential role of Gag-specific CD4+ T-cell...

Virus type antibodies inhibit recombinant AAV2-mediated gene transfer.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (RAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain. According to a study from...

New approaches to Alzheimer disease therapeutics being developed.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Researchers are developing new approaches to Alzheimer disease therapeutics. According to a study from Australia, "Abnormal proteinaceous deposits are found in the brain of patients with many...

Study says vaccine treatment slowed memory slide in Alzheimer patients.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- An experimental vaccine for Alzheimer disease slowed memory decline somewhat even though the research was stopped before the full treatment could be administered, a study suggests. There's no...

Immunological memory promotes immunity by anthrax antigen-based vaccine.
August 11, 2004... 2004 AUG 11 - (NewsRx.com & NewsRx.net) -- Immunological memory contributes to the protective immunity conferred by a Bacillus anthracis protective antigen-based vaccine. "Protective antigen (PA)-based vaccination is an effective...