Vaccine Weekly articles from August 1999

Vaccine Weekly archives from August 1999

B Cells: New Target for Arthritis Therapy?(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Abnormal B-cell responses may be the key to new treatments for arthritis and other autoimmune diseases. Most research into arthritis immunology focuses on T lymphocytes. But B-cell abnormalities...

CD4+ T Cells: First Target For Arthritis Immunotherapy.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Harnessing T cells remains the focus of rheumatoid arthritis (RA) immunotherapy. Early efforts employed monoclonal antibodies (MAbs) directed against CD4(+) T cells. Ten years of research have...

Signal Transduction Key to New Immunotherapies.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- As much as has been learned about autoimmune disease, there is exponentially more to know. Researchers trying to develop new immunosuppressive therapies thus have encountered unexpected failure...

Recombination Is Widespread in Natural Populations.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Recombination may play an important role in shaping genetic diversity in dengue virus, researchers suggest. Michael Worobey and colleagues, University of Oxford, United Kingdom, said the purpose...

Two Markers Developed for P. falciparum Transfection.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Researchers developed two markers for Plasmodium falciparum transfection. The ability to use these markers for malaria transfection should facilitate the development of drug and vaccine targets,...

Successful DNA Immunization Against M. avium Reported.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The first successful DNA vaccination against Mycobacterium avium has been reported by researchers in North Carolina. Mycobacterium avium causes disseminated disease in humans with AIDS,...

Vigilance Needed in Vaccinating Gay Men Against HBV.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Sexually active gay men are still not being vaccinated against hepatitis B virus in large enough numbers, according to the results of a Canadian study. Researcher A. Dufour and colleagues from a...

Combination HIV Vaccine Induces Diverse Immune Responses.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Preliminary analysis of data from a clinical trial testing two candidate HIV vaccines given together shows that the combination is safe and can stimulate diverse immune responses against HIV. ...

Hepatitis B Vaccine Protects Kids and Families.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Beginning July 1, 1999, students headed into the seventh grade in Los Angeles County, California, first had to stop by the doctor's office to be vaccinated against hepatitis type B. The...

Stress May Increase Susceptibility to Infectious Disease.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Researchers who have spent years studying the effects of stress on the body's immune system now believe they know enough to show that stress actually does weaken a person's health. Dozens of...

Injected Cells Boost Immune System in Humans.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A single injection of specialized immune system cells removed from the bloodstream and exposed to a foreign substance can trigger a potent immune response in humans that lasts for months, Rockefeller...

Clinical Results Vaccine Demonstrate Protection in Young Children.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Avant Immunotherapeutics, Inc., Needham, Massachusetts, announced the publication of the detailed results of a Phase II clinical study of AVANT's investigational rotavirus vaccine in The Lancet. ...

AAFP Calls for Postponement of Vaccine.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The American Academy of Family Physicians recommended that the rotavirus vaccine not be administered until additional information can be obtained and analyzed. Information from the U.S. Centers...

U.S. Vaccine Manufacturers' Statement on Thimerosal.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The following statement was released through the Pharmaceutical Research and Manufacturers of America (PhRMA): America's vaccine manufacturers are committed to producing safe and effective...

Organization Calls for HBV Vaccine Moratorium for Schoolchildren.(Statistical Data Included)
August 9, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The Association of American Physicians and Surgeons (AAPS) is calling for an immediate moratorium on mandatory hepatitis B vaccines for schoolchildren pending further research about dangerous side...

Novel Recombinant Bacterial Carriers as Potential Vaccine Candidates against Tuberculosis.(Statistical Data Included)
August 9, 1999... Vaccine Development (TB) "Novel Recombinant Bacterial Carriers as Potential Vaccine Candidates against Tuberculosis." Jurgen Hess and Stefan H.E. Kaufmann. Max-Planck-Institute for Infection Biology, Berlin, Germany. (CW HENDERSON...

Treatment of Locally Advanced or Metastatic Renal Cell Cancer Patients with an Autologous Virus-Modified Tumor Cell Vaccine.(Statistical Data Included)
August 9, 1999... Cancer Immunotherapy "Treatment of Locally Advanced or Metastatic Renal Cell Cancer Patients with an Autologous Virus-Modified Tumor Cell Vaccine." A. Hinkel, O.C. Krup, J. Alefelder, J.H. Wieland, D. Laumann, F.W. Falkenberg, L. Hertle...

Experiments on Different Immunization Routes with Two HIV-Nef Encoding Plasmids.(Statistical Data Included)
August 9, 1999... HIV Gene Therapy "Experiments on Different Immunization Routes with Two HIV-Nef Encoding Plasmids." A. Collings, M. Strengell, M. Tahtinen, A. Ranki and K. Krohn. Institute of Medical Technology, Tampere University, Finland. (CW...

Stability of Self-Amplifying HIV-1 Nef Expressing Vector and the Duration of the Immune Responses in Immunized Mice.(Statistical Data Included)
August 9, 1999... HIV Gene Therapy "Stability of Self-Amplifying HIV-1 Nef Expressing Vector and the Duration of the Immune Responses in Immunized Mice." M. Strengell, M. Tahtinen, A. Collings and K. Krohn. Institute of Medical Technology, University of...

Fusion-Competent Vaccines: Broad Neutralization of Primary Isolates of HIV.(Statistical Data Included)
August 9, 1999... HIV Vaccines "Fusion-Competent Vaccines: Broad Neutralization of Primary Isolates of HIV." J.H. Nunberg, R.A. Lacasse, K.E. Follis, M. Trahey, J.D. Scarborough and D.R. Littman. Montana Biotechnology Center, The University of Montana,...

Neutralizing Antibody-Independent Containment of Immunodeficiency Virus Challenges by DNA Priming and Recombinant Pox Virus Booster Immunizations.(Statistical Data Included)
August 9, 1999... HIV Vaccines "Neutralizing Antibody-Independent Containment of Immunodeficiency Virus Challenges by DNA Priming and Recombinant Pox Virus Booster Immunizations." H.U. Robinson, D.C. Montefiori, R.P. Johnson, K.H. Manson, M.L. Kalish, J.D....

What Is the Value of Combining Hepatitis A Vaccination with Hepatitis B Vaccination?(Statistical Data Included)
August 9, 1999... Hepatitis Vaccines "What Is the Value of Combining Hepatitis A Vaccination with Hepatitis B Vaccination?" P. Van Damme. University of Antwerp, Antwerp, Belgium. (CW HENDERSON PUBLISHER www.newsfile.com) -- According to an abstract...

Immune Response Against Mycobacterium tuberculosis: Implications for Vaccine Development.(Statistical Data Included)
August 9, 1999... Immunology (TB) "Immune Response Against Mycobacterium tuberculosis: Implications for Vaccine Development." Stefan H.E. Kaufmann and Jurgen Hess. Max-Planck-Institute for Infection Biology, Berlin, Germany. (CW HENDERSON PUBLISHER...

Six Diseases/One Vaccine - Is there a Limit?(Statistical Data Included)
August 9, 1999... Vaccine Development "Six Diseases/One Vaccine - Is there a Limit?" F. Zepp. Department of Pediatric Immunology, Johannes Gutenberg Universitat Kinderklinick, Mainz, Germany. (CW HENDERSON PUBLISHER www.newsfile.com) -- According to an...

A Mouse Model for the Evaluation of Pathogenesis and Immunity to Influenza A (H5N1) Viruses Isolated From Humans.(Statistical Data Included)
August 9, 1999... Avian Influenza Lu, X.H.; Tumpey, T.M.; Morken, T.; Zaki, S.R.; Cox, N.J.; Katz, J.M. "A Mouse Model for the Evaluation of Pathogenesis and Immunity to Influenza A (H5N1) Viruses Isolated From Humans." Journal of Virology, July...

Generation of Immunity to the HER-2/neu Oncogenic Protein in Patients with Breast and Ovarian Cancer Using a Peptide-Based Vaccine.(Statistical Data Included)
August 9, 1999... Cancer Vaccines (Breast/Ovarian Cancer) Disis, M.L.; Grabstein, K.H.; Sleath, P.R.; Cheever, M.A. "Generation of Immunity to the HER-2/neu Oncogenic Protein in Patients with Breast and Ovarian Cancer Using a Peptide-Based Vaccine."...

Vaccination with HPV16 Peptides of Patients with Advanced Cervical Carcinoma: Clinical Evaluation of a Phase I-II Trial.(Statistical Data Included)
August 9, 1999... Cancer Vaccines (Cervical Cancer) Vandriel, W.J.; Ressing, M.E.; Kenter, G.G.; Brandt, R.M.P.; Krul, E.J.T.; Vanrossum, A.B.; Schuuring, E.; Offringa, R.; Bauknecht, T.; Tammhermelink, A.; Vandam, P.A.; Fleuren, G.J.; Kast, W.M.; Melief,...

Follow-Up Evaluation of a Phase II Prostate Cancer Vaccine Trial.(Statistical Data Included)
August 9, 1999... Cancer Vaccines (Prostate Cancer) Tjoa, B.A.; Simmons, S.J.; Elgamal, A.; Rogers, M.; Ragde, H.; Kenny, G.M.; Troychak, M.J.; Boynton, A.L.; Murphy, G.P. "Follow-Up Evaluation of a Phase II Prostate Cancer Vaccine Trial." Prostate, July 1,...

Cytotoxic T-Lymphocyte Epitopes Fused to Anthrax Toxin Induce Protective Antiviral Immunity.(Statistical Data Included)
August 9, 1999... Drug Delivery Doling, A.M.; Ballard, J.D.; Shen, H.; Krishna, K.M.; Ahmed, R.; Collier, R.J.; Starnbach, M.N. "Cytotoxic T-Lymphocyte Epitopes Fused to Anthrax Toxin Induce Protective Antiviral Immunity." Infection and Immunity, July...

Potent and Stable Attenuation of Live-HIV-1 by Gain of a Proteolysis-Resistant Inhibitor of NF-kappa B (I kappa B-alpha S32/36A) and the Implications for Vaccine Development.(Statistical Data Included)
August 9, 1999... HIV Vaccines Quinto, I.; Mallardo, M.; Baldassarre, F.; Scala, G.; Englund, G.; Jeang, K.T. "Potent and Stable Attenuation of Live-HIV-1 by Gain of a Proteolysis-Resistant Inhibitor of NF-kappa B (I kappa B-alpha S32/36A) and the...

Mucosal and Systemic Immune Responses in Humans After Primary and Booster Immunizations With Orally Administered Invasive and Noninvasive Live Attenuated Bacteria.(Statistical Data Included)
August 9, 1999... Immunology Viret, J.F.; Favre, D.; Wegmuller, B.; Herzog, C.; Que, J.U.; Cryz, S.J.; Lang, A.B. "Mucosal and Systemic Immune Responses in Humans After Primary and Booster Immunizations With Orally Administered Invasive and Noninvasive Live...

Humoral Response to Influenza Vaccination in HIV Infected Patients.(Statistical Data Included)
August 9, 1999... Influenza Brydak, L.B.; Hryniewicz, H.J.; Machala, M.; Horban, A. "Humoral Response to Influenza Vaccination in HIV Infected Patients." Clinical Drug Investigation, June 1999;17(6):441-449. (CW HENDERSON PUBLISHER www.newsfile.com) --...

Identification of Multiple Protective Epitopes (Protectopes) in the Central Conserved Domain of a Prototype Human Respiratory Syncytial Virus G Protein.(Statistical Data Included)
August 9, 1999... Respiratory Syncytial Virus Plotnickygilquin, H.; Goetsch, L.; Huss, T.; Champion, T.; Beck, A.; Haeuw, J.F.; Nguyen, T.N.; Bonnefoy, J.Y.; Corvaia, N.; Power, U.F. "Identification of Multiple Protective Epitopes (Protectopes) in the...

Evidence of Avian Leukosis Virus Subgroup E and Endogenous Avian Virus in Measles and Mumps Vaccines Derived From Chicken Cells: Investigation of Transmission to Vaccine Recipients.(Statistical Data Included)
August 9, 1999... Vaccine Development Tsang, S.X.; Switzer, W.M.; Shanmugam, V.; Johnson, J.A.; Goldsmith, C.; Wright, A.; Fadly, A.; Thea, D.; Jaffe, H.; Folks, T.H.; Heneine, W. "Evidence of Avian Leukosis Virus Subgroup E and Endogenous Avian Virus in...

Gallo: HIV Vaccines Should Include Tat Toxoid.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- AIDS pioneer Robert C. Gallo says AIDS vaccines should include inactivated Tat toxoid, an antigen capable of inducing antibodies against the HIV Tat protein. Preliminary results from studies...

Live Rotavirus Vaccine 89% Effective - And Safe, Too.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A new live rotavirus vaccine appears far more effective - and at least as safe - as the currently approved vaccine. Results of a U.S. Phase II, multicenter, randomized, placebo-controlled...

Self-IgG Scaffold Lets Whole Proteins Tolerize.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Inducing tolerance - arguably the least understood aspect of immunity - just got a lot easier. This is good news to researchers seeking to treat autoimmune diseases by restoring normal tolerance...

Murine Study Links Genes to Influenza A.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Certain genes have been found to be associated with influenza A virus virulence in mouse studies. Adaption of the prototype A/FM/1/47 H1N1 strain to mice resulted in selection of the...

Lactoferrin Inhibits Adherence of Parasite-Infected Blood Cells.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Lactoferrin peptide may provide a basis for developing agents that can inhibit cytoadherence of Plasmodium falciparum infected red cells. Lactoferrin (LF), a human serum protein, strongly...

Pentagon Says Anthrax Vaccine Costs Will Double.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The Pentagon has renegotiated its contract for supplies of anthrax vaccine which will mean paying more than double the current cost per dose, U.S. Defense Department officials said. The vaccine,...

Combination Immune Therapy Kills Melanoma in Mice.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Scientists have developed a promising technique for treating the most aggressive forms of the skin cancer melanoma. The new therapy may also work for prostate cancer. The technique works by...

Researchers Advance Way To Stimulate Human Immune System.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Dendritic cells are the master control cells of the human immune system, but they aren't always successfully activated to help lead the charge against cancer or infectious disease. It may now be...

Merck Plans To Test AIDS Vaccine.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Merck & Co. Inc. scientists are making plans to begin the first human tests of two promising experimental vaccines for use against AIDS developed as part of an intense top-secret research effort,...

Technique Developed To Create Flu Viruses.(Statistical Data Included)
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A research team has perfected a method for creating designer influenza viruses, which can be tailor-made to solve mysteries about how flu strains mutate, spread, and cause illness. The...

U.S. Says Vaccine Benefits Still Outweigh Risks.
August 16, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Benefits of childhood vaccines still far outweigh the risks despite some rare injuries from the shots, U.S. Surgeon General David Satcher told the U.S. Congress. Satcher testified at a hearing...

DNA Vaccine Studies Using HIV-1 Regulatory Genes.
August 16, 1999... DNA Vaccines "DNA Vaccine Studies Using HIV-1 Regulatory Genes." M. Tahtinen, M. Strengell, A. Collings, K. Hakkarainen, J. Pitkanen, J. Pitkanenakko, M. Ustav, P. Peterson and K. Krohn. Tampere University, Finland; Tarto University,...

Immunologic Approaches to HIV-1 Therapy: Minor Successes and Major Complications.
August 16, 1999... HIV Immunotherapy "Immunologic Approaches to HIV-1 Therapy: Minor Successes and Major Complications." Donald E. Mosier. Department of Immunology-IMM7, The Scripps Research Institute, La Jolla, California 92037. (CW HENDERSON PUBLISHER...

Ambivalent Effects of CpG Oligodeoxynucleotides on the Immunogenicity of Soluble and Particulate HIV Vaccine Components.
August 16, 1999... HIV Vaccines "Ambivalent Effects of CpG Oligodeoxynucleotides on the Immunogenicity of Soluble and Particulate HIV Vaccine Components." D. Ludwig, R. Schirmbeck, H. Wolf, J. Reimann and R. Wagner. Institute of Medical Microbiology,...

Can The Immune System Control HIV?
August 16, 1999... Immunology (HIV) "Can The Immune System Control HIV?" Bruce D. Walker. Massachusetts General Hospital, Massachusetts. (CW HENDERSON PUBLISHER www.newsfile.com) -- According to an abstract submitted by the author to the 1999 Palm...

Development of Genetic Immunization with Mature CD83(+) Dendritic Cells.
August 16, 1999... Melanoma Vaccines "Development of Genetic Immunization with Mature CD83(+) Dendritic Cells." T. Tuting, H. Jonuleit, G. Miffler, J. Steitz, J. Bruck, A. Giesecke, K. Steinbrink, J. Knop and A. Erik. Department of Dermatology, University of...

Antibody Responses in Humans to an Inactivated Hantavirus Vaccine (Hantavax (R)).
August 16, 1999... Hantavirus Cho, H.W.; Howard, C.R. "Antibody Responses in Humans to an Inactivated Hantavirus Vaccine (Hantavax (R))." Vaccine, June 4, 1999;17(20-21):2569-2575. (CW HENDERSON PUBLISHER www.newsfile.com) -- According to the authors'...

Immunization with Heat-Killed Toxoplasma gondii Stimulates an Early IFN-gamma Response and Induces Protection Against Virulent Murine Malaria.
August 16, 1999... Malaria Vaccine (Animal Models) Haque, A.; Graille, M.; Kasper, L.H.; Haque, S. "Immunization with Heat-Killed Toxoplasma gondii Stimulates an Early IFN-gamma Response and Induces Protection Against Virulent Murine Malaria." Vaccine, June...

A Novel Hydrophobized GM3 Ganglioside/Neisseria meningitidis Outer-Membrane-Protein Complex Vaccine Induces Tumor Protection in B16 Murine Melanoma.
August 16, 1999... Melanoma Vaccine (Animal Models) Alonso, D.F.; Gabri, M.R.; Guthmann, M.D.; Fainboim, L.; Gomez, D.E. "A Novel Hydrophobized GM3 Ganglioside/Neisseria meningitidis Outer-Membrane-Protein Complex Vaccine Induces Tumor Protection in B16...

Rotaviruses Detected by Reverse Transcription Polymerase Chain Reaction in Acute Gastroenteritis During a Trial of Rhesus-Human Reassortant Rotavirus Tetravalent Vaccine: Implications for Vaccine Efficacy Analysis.
August 16, 1999... Rotavirus Pang, X.L.; Joensuu, J.; Hoshino, Y.; Kapikian, A.Z.; Vesikari, T. "Rotaviruses Detected by Reverse Transcription Polymerase Chain Reaction in Acute Gastroenteritis During a Trial of Rhesus-Human Reassortant Rotavirus Tetravalent...

The Effect of Reconstitution of an Haemophilus influenzae Type b-tetanus Toxoid Conjugate (PRP-T) Vaccine on the Immune Responses to a Diphtheria-Tetanus-Whole Cell Pertussis (DTwP) Vaccine: A Five-Year Follow-Up.
August 16, 1999... Vaccine Safety (Hib/DTwP Interference) Hoppenbrouwers, K.; Roelants, M.; Ethevenaux, C.; Vandermeulen, C.; Knops, J.; Desmyter, J. "The Effect of Reconstitution of an Haemophilus influenzae Type b-tetanus Toxoid Conjugate (PRP-T) Vaccine...

Self-Replicating RNA Vaccine for Cancer, Disease Therapy.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A self-replicating RNA vaccine not only protected mice against tumor challenge but also improved survival in mice with established tumors. The vaccine "self replicates" by borrowing a replicase...

Rotavirus Vaccine May Be Unsafe, CDC Warns.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Fifteen cases of bowel obstruction due to intussusception have occurred among the 1.5 million U.S. infants given the new rotavirus vaccine, and another eight cases are suspected. This rate is...

Infant HBV Vaccination Debated in Congressional Hearing.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Antivaccine groups are fighting against infant hepatitis B virus immunizations. With little scientific evidence to back them, these groups warn that the vaccine should not be given routinely to...

Novel HBV Vaccine Shows Efficacy.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A novel hepatitis B vaccine containing MF59 adjuvant appears to be safe and effective. The safety and immunogenicity of the hepatitis B virus (HBV) vaccine containing recombinant PreS2 and S...

CDC: More Effort Needed To Eliminate Tuberculosis.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- In an effort to finally stamp out tuberculosis (TB) in the United States, U.S. health officials have unveiled a plan that calls for new methods of treating and preventing the disease. The...

International Order Received for Cholera Vaccine.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Active Biotech's subsidiary SBL Vaccin has received its first big international order for its oral vaccine against cholera. The World Health Organization (WHO) has established that the cholera...

College Dorm Students At Risk for Meningitis.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Data reported in the July 1999 issue of Clinical Infectious Disease show U.S. college students living in dormitories have an 8.89 to 22.91 times greater risk of meningococcal disease than students...

Grant Received To Develop TB Vaccine Using CD1 Technology.(Statistical Data Included)
August 23, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Aquila Biopharmaceuticals, Inc., Framingham, Massachusetts, announced that it has been awarded a grant from the U.S. National Institutes of Health (NIH) to support the development of vaccines for...

IL-12 Delivery from Recombinant Vaccinia Virus Attenuates the Vector and Enhances the Cellular Immune Response Against HIV-1 ENV in a Dose-Dependent Manner.(Statistical Data Included)
August 23, 1999... HIV Vaccines "IL-12 Delivery from Recombinant Vaccinia Virus Attenuates the Vector and Enhances the Cellular Immune Response Against HIV-1 ENV in a Dose-Dependent Manner." M.M. Gherardi, J.C. Ramirez, D. Rodriguez, J.R. Rodriguez, S....

Advances in Conventional Treatment of Breast Cancer: The Addition of BCG and Autotumour Vaccine Immunotherapy.(Statistical Data Included)
August 23, 1999... Cancer Immunotherapy "Advances in Conventional Treatment of Breast Cancer: The Addition of BCG and Autotumour Vaccine Immunotherapy." R. Jiang. Monitoring Center for Cancer Therapy, Chinese Traditional Medical Hospital of Jian Ye District,...

Human HLA-A2-Specific Systemic Cytotoxic Immune Responses Induced by HIV-1 nef DNA Vaccination.(Statistical Data Included)
August 23, 1999... HIV Vaccines "Human HLA-A2-Specific Systemic Cytotoxic Immune Responses Induced by HIV-1 nef DNA Vaccination." J. Hinkula, J. Sandberg, C. Devito, A.-C. Leandersson, B. Kohleisen, V. Erfle, K. Karre and B. Wahren. Karolinska Institute,...

Design of Attenuated Recombinant Salmonella typhimurium Strains Producing HIV and HBV Antigens.(Statistical Data Included)
August 23, 1999... Vaccine Development "Design of Attenuated Recombinant Salmonella typhimurium Strains Producing HIV and HBV Antigens." L.I. Karpenko, G.M. Ignat'ev, L.R. Lebedev, V.A. Porivaeva, E.M. Kozhina, T.A. Veremelko and A.A. Hylchev. Institute of...

Antitumor Immunization With a Minimal Peptide Epitope (G9-209-2M) Leads to a Functionally Heterogeneous CTL Response.(Statistical Data Included)
August 23, 1999... Cancer Vaccines Dudley, M.E.; Nishimura, M.I.; Holt, A.K.C.; Rosenberg, S.A. "Antitumor Immunization With a Minimal Peptide Epitope (G9-209-2M) Leads to a Functionally Heterogeneous CTL Response." Journal of Immunotherapy, July...

Enhancement by IL-12 of the Cytolytic T Lymphocyte (CTL) Response of Mice Immunized With Tumor-Specific Peptides in an Adjuvant Containing QS21 and MPL.(Statistical Data Included)
August 23, 1999... Cancer Vaccines Silla, S.; Fallarino, F.; Boon, T.; Uyttenhove, C. "Enhancement by IL-12 of the Cytolytic T Lymphocyte (CTL) Response of Mice Immunized With Tumor-Specific Peptides in an Adjuvant Containing QS21 and MPL." European Cytokine...

Immunotherapy for Lung Metastases of Murine Renal Cell Carcinoma: Synergy Between Radiation and Cytokine-Producing Tumor Vaccines.(Statistical Data Included)
August 23, 1999... Cancer Vaccines Nishisaka, N.; Maini, A.; Kinoshita, Y.; Yasumoto, R.; Kishimoto, T.; Jones, R.F.; Morse, P.; Hillman, G.G.; Wang, C.Y.; Haas, G.P. "Immunotherapy for Lung Metastases of Murine Renal Cell Carcinoma: Synergy Between...

Construction of a Recombinant Live Oral Vaccine From a Non-Toxigenic Strain of Vibrio cholerae O1 Serotype Inaba Biotype E1 Tor and Assessment of Its Reactogenicity and Immunogenicity in the Rabbit Model.(Statistical Data Included)
August 23, 1999... Cholera Thungapathra, M.; Sharma, C.; Gupta, N.; Ghosh, R.K.; Mukhopadhyay, A.; Koley, H.; Nair, G.B.; Ghosh, A. "Construction of a Recombinant Live Oral Vaccine From a Non-Toxigenic Strain of Vibrio cholerae O1 Serotype Inaba Biotype E1...

Therapeutic Antibodies Elicited by Immunization Against TNF-alpha.(Statistical Data Included)
August 23, 1999... Inflammatory Disease Dalum, I.; Butler, D.M.; Jensen, M.R.; Hindersson, P.; Steinaa, L.; Waterston, A.M.; Grell, S.N.; Feldmann, M.; Elsner, H.I.; Mouritsen, S. "Therapeutic Antibodies Elicited by Immunization Against TNF-alpha." Nature...

Comparison of L Proteins of Vaccine and Wild-Type Measles Viruses.(Statistical Data Included)
August 23, 1999... Measles Bankamp, B.; Bellini, W.J.; Rota, P.A. "Comparison of L Proteins of Vaccine and Wild-Type Measles Viruses." Journal of General Virology, July 1999;80(Part 7):1617-1625. (CW HENDERSON PUBLISHER www.newsfile.com) -- According to...

Characteristics of Families Who Attend Free Vaccine Fairs.(Statistical Data Included)
August 23, 1999... Pediatrics Hambidge, S.J.; Easter, S.A.; Martin, S.; Melinkovich, P.; Brown, J.; Siegel, C.D. "Characteristics of Families Who Attend Free Vaccine Fairs." Pediatrics, July 1999;104(1 Suppl. S):158-163. (CW HENDERSON PUBLISHER...

Previous Exposure to Measles, Mumps, and Rubella - But Not Vaccination During Adolescence - Correlates to the Prevalence of Pancreatic and Thyroid Autoantibodies.(Statistical Data Included)
August 23, 1999... Pediatrics Lindberg, B.; Ahlfors, K.; Carlsson, A.; Ericsson, U.B.; Landinolsson, M.; Lernmark, A.; Ludvigsson, J.; Sundkvist, G.; Ivarsson, S.A. "Previous Exposure to Measles, Mumps, and Rubella - But Not Vaccination During Adolescence -...

Safety and Effectiveness of BCG Vaccination in Preterm Babies.(Statistical Data Included)
August 23, 1999... Tuberculosis (Vaccines) Thayyilsudhan, S.; Kumar, A.; Singh, M.; Paul, V.K.; Deorari, A.K. "Safety and Effectiveness of BCG Vaccination in Preterm Babies." Archives of Disease in Childhood, July 1999;81(1 Sp. Iss.):F64-F66. (CW...

CpG Motifs Motivate Human DCs.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A bacterial DNA motif greatly increases the growth, activation, and maturation of human dendritic cells. Dendritic cells (DCs) are the body's key antigen-presenting cells (APCs). They represent...

DNA/MVA Prime/Boost = Specific CTLs.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A new prime/boost vaccine regimen efficiently induces specific cytotoxic lymphocyte (CTL) responses in the rhesus monkey model of AIDS. The majority of AIDS researchers believe that an effective...

War on Polio Fights War Itself.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Polio eradication is possible even in the most war-torn regions of the world, suggests the U.S. Centers for Disease Control and Prevention (CDC). This optimistic conclusion is based on experience...

Combined Hepatitis A/B Vaccine Shown Effective.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A combined hepatitis A and B vaccine, administered in a two-dose schedule, was found to be efficacious and well-tolerated in a study involving children in Taiwan. Researcher S.D. Lee and...

Scientists Report X-Rays Show How Bacteria Infect Cells.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Two teams of scientists said they had been able to take pictures of the tiny structures used by bacteria to infect cells, and said their studies may lead to new ways to fight disease. The...

Virus Potentially Linked to Aggressive Breast Cancer.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- The virus that causes glandular fever, also known as "kissing disease," may also play a role in many cases of breast cancer, European researchers said. They said they found Epstein-Barr virus...

Progress Reported Toward Vaccine To Fight Cocaine Addiction.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- A potential vaccine against the addictive effects of cocaine was described at the National Meeting of the American Chemical Society, held in New Orleans, Louisiana, during August 1999. Kim D....

Britain To Vaccinate Children Against Meningitis C.(Statistical Data Included)
August 30, 1999... (CW HENDERSON PUBLISHER www.newsfile.com) -- Britain is to start vaccinating hundreds of children in a village in the north of the country with a new meningitis C vaccine after a cluster of recent cases, the Health Ministry said. A...