Vaccine Weekly articles from April 2003

Vaccine Weekly archives from April 2003

23-Valent pneumococcal revaccination offers short-term protection for elderly.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A brief but significant immune response was obtained in frail elderly adults by revaccination with a 23-valent pneumococcal polysaccharide vaccine if...

Promoter trap system increases expression of protective antigen.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Vaccines containing live attenuated Bacillus anthracis or Bacillus subtilis expressing recombinant protective antigen (rPA) were made more potent by...

Dendritic cell vaccine shows promise against cervical cancer.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Vaccination with dendritic cells pulsed with tumor lysate and matured with a novel synthetic clinically nontoxic, double-stranded RNA analogue poly [I]:poly[C[subscript]12U] (Ampligen) induced a strong...

New non-immunizing, paraspecific vaccines from attenuated pox viruses developed.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A new type of non-immunizing, paraspecific vaccines have been developed from attenuated pox viruses. According to recent research from Germany, "The various research periods leading to the...

Stabilization of dry powder vaccine formulations enhanced by rapid freezing.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Stabilization of alum-adjuvanted vaccine dry powder formulations was enhanced by a rapid freezing technique followed by lyophilization. "Studies were performed to elucidate the mechanism of alum gel...

Enterovirus induces antibody response with islet cell autoantigens in humans.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- An enterovirus infection may induce a humoral immune response reacting with islet cell autoantigens in humans. According to a study from Finland, "Molecular mimicry is one of the mechanisms by...

Ovalbumin allergenic peptide effective for allergic airway inflammation.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- An E. coli strain carrying an ovalbumin allergenic peptide as a fused protein to OMPC was therapeutic in a murine model of allergic airway inflammation. According to a study from Mexico, "An...

Autopsy exposes adverse effects of vaccine.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The only clinical trial for an experimental Alzheimer disease (AD) vaccine was halted last year when 15 of the trial participants developed severe brain inflammation. Now James Nicoll and colleagues...

Biotech firm plans to test vaccine on humans by year's end.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A San Diego biotechnology firm says it hopes to begin human testing of its experimental anthrax vaccine by year's end. Several companies and government researchers are racing to create a better...

Safer vaccine possible using spinach.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine, enlisting the help of spinach plants to manufacture a key component. They reported their...

CD40-directed gene therapy shows prospects for treating human cancers.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- CD40-directed gene therapy shows prospects for treating human cancers. According to a study from the United States, "CD40, a member of the tumor necrosis factor receptor (TNF-R) family, is a surface...

Cancer treated using vaccines in mixed allogeneic bone marrow chimeras.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Successful therapy of metastatic cancer was achieved using tumor vaccines in mixed allogeneic bone marrow chimeras. According to a study from the United States, "A frequent outcome of allogeneic...

BvgA and RNA polymerase alpha subunit bind to different faces of DNA.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The response regulator BvgA and RNA polymerase alpha subunit C-terminal domain bind simultaneously to different faces of the same segment of promoter DNA. "Examination of the binding of...

Vaccination with plasmids of infectious bursal disease virus protective.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- DNA vaccination with plasmids containing various fragments of large segment genome of infectious bursal disease virus protected chickens against disease. "The present study was undertaken to...

Novel molecular conjugates aid signal amplification for immunodiagnostic assays.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The conjugation of multiple horseradish peroxidase molecules to immunoglobulin via primary amines on lysine peptide chains provided novel molecular conjugates for signal amplification. According to...

Salmonella secretion antigen delivery primes SIV-specific T-cell response.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses were found in rhesus macaques that received a Salmonella type III secretion antigen delivery system. ...

Live-attenuated SIV expressing interleukin-4 stimulate immune response.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Live-attenuated simian immunodeficiency viruses expressing interleukin-4 or interferon-gamma stimulated an immune response in macaques. According to recent research from Germany, "Nef deletion...

Molecular characteristics of HIV-1 subtype C viruses elucidated.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A study of the molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from KwaZulu-Natal, South Africa has resulted in implications for vaccine and antiretroviral control...

Recipients at risk for false positive test results.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Several HIV vaccine candidates cause a high rate of false positive test results, researchers in the United States warn. "Since 1987, more than 10,000...

Researchers test vaccine in hopes of cutting cervical cancer rate.(University of Alabama at Birmingham )(Brief Article)
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Alabama at Birmingham (UAB) are joining the effort to test a vaccine that they hope will keep women from contracting human papillomavirus (HPV), a common infection that...

Influenza vaccine recipients more likely to have heart and lung conditions.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Patients who received influenza and pneumococcal vaccinations in Sweden were more likely to have chronic lung and heart conditions than those who were unvaccinated. "This study characterizes...

Viral gene responsible for oncogenesis identified.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The guilty gene responsible for initiating oncogenesis in Kaposi sarcoma has been identified - at last - by researchers at Weill Cornell Medical College. Kaposi sarcoma associated herpes virus...

Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The Leishmania mexicana cysteine protease, CPB2.8, induced a potent Th2 response in mice. "We have previously identified that Leishmania mexicana cysteine proteases (CPs) are virulence factors. We...

Scientific panel finds long-lasting vaccine for Africa promising.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The Meningitis Vaccine Project (MVP), a partnership between the World Health Organization (WHO) and the Seattle-based Program for Appropriate Technology in Health (PATH), has announced a major milestone...

Bactericidal activity correlates with N. meningitidis vaccine efficacy.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Serum bactericidal activity correlates with the vaccine efficacy of outer membrane vesicle vaccines against Neisseria meningitidis serogroup B disease. "For evaluation of serum bactericidal activity...

CDC: Spike in India's polio cases prompts vaccination rally.(Brief Article)
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The number of polio cases in India last year rose six-fold from 2001, U.S. health officials say. In 2002, 1,556 cases of wild polio virus were found in India, up from only 268 cases a year earlier,...

Vaccines not linked to crib death, study said.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- There is no evidence of a link between crib death - known as sudden infant death syndrome (SIDS) - and multiple vaccines given in infancy, a study concludes. Many parents became concerned about...

Pertussis toxin enhances Th1 responses by stimulation of dendritic cells.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- The pertussis toxin enhances Th1 responses by stimulation of dendritic cells. According to a study from the People's Republic of China, "Pertussis toxin (PTX) has been widely used as an adjuvant to...

Bacterial viruses make cheap easy vaccines.(Moredun Research Institute )(Brief Article)
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- Genetically altered bacterial viruses appear to be more effective than naked DNA in eliciting an immune response and could be a new strategy for a next generation of vaccines that are easy to produce...

CD40, B7, and major histocompatibility complex enhance immunity.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- CD40, B7, and the major histocompatibility complex play roles in the induction of enhanced immunity by cryptococcal polysaccharide-pulsed antigen-presenting cells. "Immunization of mice with...

Epidemiology of measles, mumps, and rubella in Italy reviewed.
April 2, 2003... 2003 APR 2 - (NewsRx.com & NewsRx.net) -- A recent report presents details on the epidemiology of measles, mumps, and rubella in Italy. According to a study from Italy, "A serosurvey for measles, mumps, and rubella was conducted in Italy;...

Vaccine containing outer-surface protein A protects against Lyme disease.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Long waits in doctors' offices are an obstacle to universal pediatric influenza vaccination, according to a report published in the Archives of...

Vaccine containing outer-surface protein A protects against Lyme disease.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A Lyme disease vaccine (lipo-OspA) containing outer-surface protein A (OspA) effectively prevented the disease in individuals who experienced a strong...

Pancreatic cancer patient successfully treated with dendritic cell vaccine.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- The successful treatment of a pancreatic cancer patient who received multiple doses of a vaccine consisting of dendritic cells pulsed with allogeneic tumor lysate may provide insights into new...

IgA response greater with intranasal than intramuscular vaccine delivery.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Intranasal delivery of an influenza vaccine stimulated a greater IgA response than did intramuscular delivery vaccine delivery in elderly residents of a nursing home. "Intramuscular (IM) influenza...

Influenza vaccines from two facilities have similar safety and efficacy profiles.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- The safety and immunogenicity profiles of live-attenuated influenza vaccines blended and filled at two manufacturing facilities were similar. According to recent research from Australia, "This study...

Subunit-adjuvanted influenza vaccine more immunogenic than split vaccine.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- A subunit-adjuvanted influenza vaccine was more immunogenic in elderly subjects compared with an inactivated split virion influenza vaccine. "A randomized, open study was carried out among an...

CDC says 22 in U.S. may have SARS.(Centers for Disease Control and Prevention)(Brief Article)
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- The U.S. government increased to 22 the number of people in America suspected of having the mysterious flu-like illness that has sickened hundreds in Asia. The suspected cases of those made ill by...

Scientists find mystery illness virus, verify diagnostic test.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Scientists are perfecting a test to diagnose a newly discovered virus believed to be responsible for the mystery illness that has sickened hundreds of people worldwide. The World Health...

CD4+CD25+ lymphocytes play role in immune response to melanoma antigens.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- CD4+CD25+ suppressor lymphocytes in the circulation of patients immunized against melanoma antigens may play a role in the immune response. "Murine studies have suggested that a population of CD4+ T...

HPV16-associated, MHC class I+ tumors more susceptible than class I- to therapy.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Chemoimmunotherapy was more effective in mice carrying HPV16-associated, MHC class I+ tumors than in those carrying and class I- tumors. According to recent research from Czech Republic, "The...

Immature dendritic cell vaccine causes immune response against melanoma.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- The clinical response after intradermal immature dendritic cell vaccination for metastatic melanoma was associated with an immune response to particulate antigen. According to recent research from...

Rapid generation of antigen-presenting cells from leukemic blasts developed.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- A method for the rapid generation of antigen-presenting cells from leukemic blasts in acute myeloid leukemia has been developed. "The ability of acute myeloid leukemia (AML) cells to acquire...

Dendritic cells generated in serum-free medium using cytokine combinations.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Antigen-loaded dendritic cells were generated in a serum-free medium using different cytokine combinations. According to a study from Czech Republic, "Dendritic cells (DCs) are antigen-presenting...

Body's own antibodies may drive new strains of HIV.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Scientists in California have provided the first detailed look at how human antibodies, proteins critical for the body's defense against invading pathogens, may actually drive human immunodeficiency...

"Partially effective" AIDS vaccine may be beneficial.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Even a "partially effective" AIDS vaccine may offer considerable benefits in combating the disease. According to a study from the United States, "A safe, effective, and affordable vaccine remains...

Virus-cross-HIV-1-neutralizing antibodies induced by in vivo expression system.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Primary virus-cross-reactive human immunodeficiency virus type 1-neutralizing antibodies were induced in small animals using an alphavirus-derived in vivo expression system. According to a study...

Health department seeks funds to develop new vaccines.(Brief Article)
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- The Bush administration wants to spend $100 million to work toward vaccines to shield Americans from global outbreaks of new flu strains. U.S. Health and Human Services Secretary Tommy Thompson told...

Countries must cooperate to protect infants against measles.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Countries must cooperate to provide wide vaccine coverage in order to protect infants against measles. According to a study from Australia and Papua New Guinea, "Measles is the most frequent cause...

Immunogenicity of meningococcal PorA restored by incorporation into liposomes.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Functional immunogenicity of purified meningococcal PorA was restored by incorporating them into liposomes. "The impact of the conformation, lipo-oligosaccharide (LOS)-depletion and the...

Cholera toxin B subunit may not be helpful as adjuvant in pertussis vaccine.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Cholera toxin B subunit may not be helpful as an adjuvant in an intranasal pertussis toxoid vaccine. "To investigate the possibility of intranasal immunization with an acellular pertussis vaccine,...

Pace of inoculations picks up.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- The pace of smallpox shots for U.S. health care workers is picking up, with vaccinations under way in all but one state, federal health officials say. Still, with nearly 21,698 workers vaccinated so...

ACAM2000 completes phase I trial.(Brief Article)
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- Acambis, plc, (ACAM) announced that it has completed a phase I trial of its smallpox vaccine, ACAM2000. The trial assessed the safety, tolerability, and immunogenicity of ACAM2000 in adult subjects...

Aluminum hydroxide adjuvant affects sensitization toward OVA inhalation.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- An aluminum hydroxide adjuvant was able to modulate the development of sensitization or tolerance following repeated OVA inhalation in BALB/cJ mice. "Anthropogenically induced exposures may, due to...

Single dose of Salmonella typhimurium induces humoral immune response.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- A single dose of recombinant Salmonella typhimurium induced specific humoral immune responses against heterologous Eimeria tenella antigens in chickens. According to recent research from Germany,...

Human hookworm vaccine containing hookworm larvae protects against infection.
April 9, 2003... 2003 APR 9 - (NewsRx.com & NewsRx.net) -- BALB/c mice were successfully vaccinated against human hookworm (Necator americanus) by using N. americanus larvae. According to recent research from England, "In this murine (BALB/c) model of...

Pre-pro sequence needed for DNA vaccine to induce dust mite allergen antibodies.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- A pre-pro sequence is necessary for a DNA vaccine encoding the dust mite allergen, Der p 1, to induce antibody response, found researchers in Singapore. "The mite protein Der p 1 is a major trigger...

Transgenic carrots can be made to express edible antiviral vaccine.(for measles prevention)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Researchers in Luxembourg have demonstrated that transgenic carrots can be made to express edible measles vaccine. These would be eaten raw to preserve full immunogenicity. "Although edible...

EFRH-phage immunization reduces beta-amyloid plaques in transgenic mouse brain.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- EFRH-phage immunization reduced the number beta-amyloid plaques in the brain of transgenic mice in a study by Tel Aviv University molecular microbiologists. "Antibodies to the epitope EFRH,...

Infection spread inhibited by DNA immunization with C. trachomatis pgp3 gene.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- In experiments with C3H/HeN mice, DNA immunization with the pgp3 gene of "Chlamydia trachomatis inhibited spread of the bacterial infection from the lower genital tract to the upper. M. Donati and...

Immune competence may partly determine DC immunotherapy response.(dendritic cell-based immunotherapy for metastatic melanoma)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Queensland suggest assessing melanoma patients' general immune competence before administering dendritic cell-based immunotherapy as this can affect treatment response....

Anticipatory vaccination recommended for segments of populations.(smallpox vaccine distribution)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Virologists in Britain recommend that segments of populations in areas that might be considered targets for bioterrorism should be vaccinated against smallpox. P.P. Mortimer and colleagues asked,...

Guanosine-rich PO ODN may be alternative approach to development.(phosphodiester oligodeoxynucleotides for vaccine adjuvants)(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Guanosine-rich phosphodiester oligodeoxynucleotides (PO ODN) may be an alternative approach to the development of effective and safe vaccine adjuvants, say microbiologists at the University of Marburg....

Case reported of rare systemic dermatologic reaction after pneumococcal vaccine.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Physicians in Louisiana have reported the case of a 65-year-old man who experienced "a rare dermatologic reaction" after receiving pneumococcal vaccine. The patient "developed an extensive...

Oral vaccine conveys immunity in murine study.(type F botulinum toxin prevention)(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- A study in mice has demonstrated that an oral vaccine conveyed immunity against botulinum toxin type F. S. Foynes and colleagues, University of London Imperial College of Science, Technology &...

Antenatal hepatitis B screening program effective in Italian women.
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Italy's antenatal hepatitis B screening program is effective in preventing perinatal transmission of the disease, an epidemiologic study found. T. Stroffolini and colleagues evaluated the program's...

Phase II colorectal trial results for Theratope vaccine to be presented at ASCO.(Biomira Inc. colorectal cancer vaccine)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Biomira, Inc., (BIOM; BRA) announced that data from the company's phase II Theratope vaccine trial in metastatic colorectal cancer will be presented as a poster presentation at the 2003 Annual Meeting...

Genome sequences of three South African HIV type 1 subtype C isolates characterized.
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- The near-full length genome sequences of three South African human immunodeficiency virus (H(V) type 1 subtype C isolates have been characterized. G.M. Hunt and colleagues at the University of...

HIV specific immune responses boosted by structured treatment interruptions.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Results of a study by Immune Response Corp. scientists back the idea that HIV specific immune responses play a role in control of viremia. "The immunologic correlates associated with control of...

Tat-neutralizing antibodies compared in vaccinated macaques.(AIDS vaccine development)(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Researchers at the Institute of Human Virology, at the University of Maryland, compared antisera of macaques immunized with Tat or chemically modified Tat toxoid having the same clade B sequence "for...

Recombinant SFV expressing fusion protein eliminated tumors in vaccinated mice.(Semliki Forest virus)(human papillomavirus infection vaccine)(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Recombinant Semliki Forest virus expressing a fusion protein of human papillomavirus E6 and E7 eliminated tumors in immunized mice, virologists report. According to researchers in the Netherlands,...

MF59C.1-adjuvanted recombinant vaccine reported safe, immunogenic.(human parvovirus B19 vaccine)(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- A recombinant human parvovirus B19 vaccine formulated with MF59C.1 adjuvant was found safe and immunogenic in a small, Phase I clinical trial. Medimmune Inc. reported the safety and immunogenicity...

Understanding mucosal immunity may lead to new vaccines.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Local mucosal immunization leads to antigen-specific IgA production at distant mucosal sites, presumably through the migration of activated B cells. Because of the important implications for vaccine...

Researchers model evolution of virus.(severe acute respiratory syndrome cause sought)(influenza virus evolution analyzed)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- As health agencies around the world race to pinpoint the cause of severe acute respiratory syndrome (SARS), researchers are reporting success in developing a new theoretical model that shows how the...

DNA vaccine encoding ORFF confers protective immunity in mice.(against leishmaniasis)(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- A DNA vaccine encoding the ORFF gene conferred protective immunity in mice infected with Leishmania donovani, according to a report from India. "The gene ORFF is part of the multigenic LD1 locus on...

Four months since reports of D9 virus in Western Hemisphere.(measles virus outbreak)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- The countries of the Americas have not reported new cases of transmission of the d9 measles virus, the strain responsible for the only large outbreak of measles in the region during 2002, for more than...

Suppressor lymphocytes may modify T-cell response to anti-tumor immunization.
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- CD4+CD25+ suppressor lymphocytes may modify the T-cell response of melanoma patients' T-cell response undergoing tumor antigen immunization, according to a study by U.S. National Institutes of Health...

Anti-cancer DNA vaccination is less effective in older mice than younger.(Brief Article)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- Study results showed that DNA vaccination to induce immunity against cancerous tumors was less effective in older mice than younger animals. The researchers conducting the work suggest this would...

Compensation urged in vaccine program.(in case of injuries caused by smallpox vaccine)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- If the U.S. government wants a successful smallpox inoculation program, it must provide money to the states and compensation to people injured by the vaccine, the Institute of Medicine says. ...

Study says vaccinated health workers present greater risk for patients.(patient contact with workers innoculated with smallpox vaccine may pose risk )
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- More than half of all New York state hospital patients may face an increased risk of complications from contact with smallpox-vaccinated health care workers, a study suggests. With the voluntary...

Temporary deferral recommended for heart patients volunteering for vaccine.(smallpox vaccine)
April 16, 2003... 2003 APR 16 - (NewsRx.com & NewsRx.net) -- The U.S. Centers for Disease Control and Prevention (CDC) has taken the precautionary step of adding a temporary medical deferral to the smallpox vaccination program for people who have been diagnosed...

Venezuelan equine encephalitis virus used as vector in anthrax vaccine.
April 30, 2003... 2003 APR 30 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Vaccines using Venezuelan equine encephalitis virus as a vector protected mice against challenge with Bacillus anthracis, according to a report in...

Hepatitis B vaccination program a resounding success in Taiwan.
April 30, 2003... 2003 APR 30 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The hepatitis B virus (HBV) vaccination program for children in Taiwan has been successful at significantly reducing perinatal and horizontal...

Novel liposomal influenza subunit vaccine safe and effective in young adults.
April 30, 2003... 2003 APR 30 - (NewsRx.com & NewsRx.net) -- A novel liposomal influenza subunit vaccine (INFLUSOME-VAC) was safe and effective in young adults. According to recent research from Israel, "Influenza and its complications account for...