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Sabinsa granted third patent on Bioperine bioavailability enhancing phytonutrient.(Brief Article)
December 1, 1999... Sabinsa Corporation (Piscataway, NJ; 732-777-1111) has been granted its third patent on Bioperine, a proprietary ingredient developed by the company which has been clinically shown to increase the bioavailability of nutritional supplements,...
Associated Pathologists Laboratories awarded second United States patent.(Brief Article)(Statistical Data Included)
December 1, 1999... Associated Pathologists Laboratories (Las Vegas, NV; 702-733-7866) has received notification from the United States Patent and Trademark Office that a second patent has been issued for Associated Pathologists' unique method of detecting drugs...
Dow AgroSciences files cotton patent litigation suit against Monsanto.(Brief Article)(Statistical Data Included)
December 1, 1999... Mycogen Plant Science, Inc., an affiliate of Dow AgroSciences LLC (Indianapolis, IN; 317-337-4792), announced it has filed suit in the Federal Court of Australia, Victoria District Registry (Melbourne, Australia), against Monsanto Australia...
ILEX Oncology and Millennium submit biologics license application for CAMPATH.(Brief Article)
December 1, 1999... ILEX Oncology, Inc. (San Antonio, TX; 210-949-8230), and Millennium Pharmaceuticals, Inc. (Cambridge, MA; 617-679-7480), which recently acquired LeukoSite, Inc., announced the submission of a Biologics License Application to the United States...
Human Genome Sciences announces exercise of option.(Brief Article)(Statistical Data Included)
December 1, 1999... Human Genome Sciences, Inc. (Rockville, MD; 301-309-8504) announced that the initial purchaser, Credit Suisse First Boston, for its recently completed private placement of $150 million principal amount of 5% Convertible Subordinated Notes due...
Millennium announces the completion of LeukoSite and Millennium BioTherapeutics mergers.(Brief Article)(Statistical Data Included)
December 1, 1999... Millennium Pharmaceuticals, Inc. (Cambridge, MA; 617-577-3548) announced the completion of its merger with LeukoSite, Inc., in which Millennium acquired LeukoSite in a stock-for-stock exchange. As a result of the merger, LeukoSite...
Aquasearch awarded another patent for microalgae production technology.(Brief Article)(Statistical Data Included)
December 1, 1999... Aquasearch Inc. (Kailua-kona, HI; 808-988-6580) announced the award of another patent relating to its proprietary microalgae production technology. The Brazilian Patent Office issued a patent for "Process and Apparatus for the Production of...
Biosite signs collaboration and phage display licensing agreement with MorphoSys.(Brief Article)(Statistical Data Included)
December 1, 1999... Biosite Discovery, the collaborative antibody development program of Biosite Diagnostics, Inc. (San Diego, CA; 858-455-4808), has yielded its fifth collaboration. According to Kim Blickenstaff, Biosite president and chief executive officer,...
SafeScience announces issuance of patent for Elexa fungal infection inhibitor.(Statistical Data Included)
December 1, 1999... SafeScience, Inc. (Boston, MA; 617-422-0674) announced that the United States Patent and Trademark Office has issued patent number 5,965,545 for the company's Elexa-Plant Defense Booster. The patent covers composition of matter and methods of...
Chiron settles infringement suit against Gilead.(Brief Article)
December 1, 1999... Chiron Corporation (Emeryville, CA; 510-923-6686) announced that it has settled its lawsuit against Gilead Sciences (Foster City, CA; 415-574-3000), a biotechnology company, for infringement of Chiron's United States hepatitis C virus protease...
Abgenix to become sole owner of XenoMouse fully human antibody technology.(Brief Article)(Statistical Data Included)
December 1, 1999... Abgenix, Inc. (Fremont, CA; 510-608-6575) will become the sole owner of the XenoMouse, a leading technology for generating fully human antibody drugs useful in treating a wide range of diseases, by acquiring all of the interest in the...
Millennium delivers validated target in prostate cancer for screening to Eli Lilly.(Brief Article)(Statistical Data Included)
December 1, 1999... Millennium Pharmaceuticals, Inc. (Cambridge, MA; 617-679-7480) announced that one of its partners in oncology, Eli Lilly and Company (Indianapolis, IN; 317-261-2000), has accepted a validated target for drug candidate screening in the field of...
Demegen awarded United States patent for stabilized peptides and method for treating cancers and other diseases.(Brief Article)
December 1, 1999... Demegen, Inc. (Pittsburgh, PA; 412-241-2150) was awarded United States Patent 5,968,904 by the United States Patent and Trademark Office for the composition of, and method of making, synthetic peptides in a form that is resistant to...
Life Technologies releases novel universal cloning technology and its adoption by key programs providing clones.(Brief Article)
December 1, 1999... Life Technologies, Inc. (Rockville, MD; 301-610-8000) released to the public a novel universal cloning technology in response to the growing need engendered by the genomics revolution for faster, more efficient ways to clone and express DNA...
Gene Logic discovers genes for renal disease.(Brief Article)
December 1, 1999... Gene Logic, Inc. (Gaithersburg, MD; 301-987-1824) announced that the company has reached the first major milestone in its alliance with Japan Tobacco, Inc. (Tokyo, Japan; 03-582-3111) to discover novel drugs for the treatment of kidney...
Affymetrix and Orchid announce alliance to develop and commercialize new GeneChip genotyping assays.(Brief Article)
December 1, 1999... Affymetrix (Santa Clara, CA; 408-731-5000) and Orchid Biocomputer, Inc. (Princeton, NJ; 609-750-2200) announced that they have entered into an agreement to develop and commercialize single nucleotide polymorphism genotyping assays that combine...
Quidel exclusive licensee for patent granted for peptide used in managing osteoporosis.(Brief Article)
December 1, 1999... Quidel Corporation (San Diego, CA; 858-552-7962) announced that a patent was granted on a helical peptide believed to be valuable in measuring bone resorption. The patent covers an immunoassy method for measuring this peptide derived from...
Cambridge NeuroScience receives two United States patents and three United States patent allowances.(Brief Article)
December 1, 1999... Cambridge NeuroScience, Inc. (Cambridge, MA; 617-225-0600) was awarded the company two additional patents by the United States Patent and Trademark Office, and notified that three other patent applications have been allowed covering various...
Ventana sues Cytologix for patent infringement.(Brief Article)
December 1, 1999... Ventana Medical Systems, Inc. (Tucson, AZ; 520-887-2155) filed suit in the United States District Court in Phoenix, Arizona against CytoLogix Corporation (Cambridge, MA) for infringement of its patent covering the methods and systems for...
Nemours Foundation obtains United States patent.(Brief Article)
December 1, 1999... The Nemours Foundation (Jacksonville, FL) has patented a diagnostic method for determining whether an individual is affected with spinal muscular atrophy involves evaluating the relative amounts of exon 5 of Neuronal Apoptosis Inhibitory...
Royal Veterinary obtains United States patent.(Brief Article)
December 1, 1999... Royal Veterinary Agricultural University (Copenhagen, Denmark) has patented cytochrome P-450 dependent monooxygenases and DNA molecules encoding these monooxygenases, which are able to catalyze the biosynthetic pathway from amino acids to...
Boehringer Mannheim obtains United States patent.(Brief Article)
December 1, 1999... Boehringer Mannheim GmbH (Mannheim, Germany) has patented monoclonal antibodies, humanized monoclonal antibodies and functional derivatives thereof specific for the platelet-derived growth factor receptor beta. (US 5882644)
University of Maryland obtains United States patent.(Brief Article)
December 1, 1999... University of Maryland (Baltimore, MD) has patented fungi and fungal spores which are modified to confer a transmissible hypovirulent phenotype, related polynucleotides, and use of these fungi to control fungal diseases. (US 5882642)
Transgene obtains United States patent.(Brief Article)
December 1, 1999... Transgene S A (Courbevoie, France) has patented a system for producing mature heterologous proteins, and especially hirudin, by means of yeasts comprising an expression vector containing a sequence coding for the heterologous protein. (US...
Connaught obtains United States patent.(Brief Article)
December 1, 1999... Connaught Laboratories Ltd. (North York, Canada) has patent non-infectious, retrovirus-like particles which comprise an assembly of an env gene product, a pol gene product and a gag gene product contain an antigenic marker which is...
Novo Nordisk obtains United States patent.
December 1, 1999... Novo Nordisk A/S (Bagsvaerd, Denmark) has patented alkaline glucose oxidases comprising novel peptide sequences, and methods for producing and using said glucose oxidases. (US 5879921)
Pioneer Hi-Bred obtains United States patent.
December 1, 1999... Pioneer Hi-Bred International, Inc. (Des Moines, IA) has patented a process of transporting biological materials into living cells by bombarding the cells with microprojectile particles coated with biological material. In the process, prior to...
Energy Biosystems obtains United States patent.
December 1, 1999... Energy Biosystems Corporation (The Woodlands, TX) has patented a recombinant DNA molecule containing a gene or genes which encode a biocatalyst capable of desulfurizing a fossil fuel which contains organic sulfur molecules, e.g., a recombinant...
Institut Francais du Petrole obtains United States patent.
December 1, 1999... Institut Francais du Petrole (France) has patented a process for the production of sophorolipids by a stock of Candida bombicola or apicola in a medium that contains a source of nitrogen and a substrate. The process includes a first...
MTA Szegedi Biologiai Kozpontja obtains United States patent.
December 1, 1999... MTA Szegedi Biologiai Kozpontja (Budapest, Hungay) has patented a structural gene coding for authentic human serum albumin, -optionally supplemented by an upstream triplet coding for methionine and optionally extended by a synthetic prepro sup...
Institut Pasteur obtains United States patent.
December 1, 1999... Institut Pasteur (Paris, France) has patented oligonucleotides encoding HCV E1 peptides, labeled oligonucleotide probes, recombinant DNA molecules comprising HCV E1 nucleotides, plasmids, expression vectors, transformed hosts, analytical kits...
Neuro-Biotech obtains United States patent.(Brief Article)
December 1, 1999... Neuro-Biotech, Inc. (Sainte-Foy, Canada) has patented an in vitro diagnostic method for the determination of specific dopamine- beta -hydroxylase activity for the evaluation of the sympathetic nervous system function of a patient from a serum...
Isis obtains United States patent.(Brief Article)
December 1, 1999... Isis Innovation Ltd. (Oxford, England) has patented a method of diagnosing neoplasia by analysis of a sample of body tissue or body fluid or waste product for marked over-expression of multiple spliced variants of the CD44 gene in tumor...
Ludwig Institute obtains United States patent.
December 1, 1999... Ludwig Institute for Cancer Research (New York, NY) has patented leukemia associated genes, including fragments and biologically functional variants thereof. Methods and products also are provided for diagnosing and treating conditions...
Indiana University obtains United States patent.
December 1, 1999... Indiana University (Bloomington, IN) has patented a method for screening for risk of Alzheimer's disease which involves assaying for a guanine to thymine substitution at position 1924 of the gene encoding the human amyloid precursor protein....
Corixa obtains United States patent.
December 1, 1999... Corixa Corporation (Seattle, WA) has patented methods for eliciting or enhancing immune responses to antigens, including tumor antigens, and/or DNA vaccines which employ polypeptides or nucleic acid compositions that contain at least a...
Scripps Research Institute obtains United States patent.(Brief Article)
December 1, 1999... The Scripps Research Institute (La Jolla, CA) has patented a method for inhibiting tissue factor mediated reperfusion damage in a subject by administration of tissue factor-specific monoclonal antibodies of tissue factor peptides which prevent...
Thomas Jefferson University obtains United States patent.(Brief Article)
December 1, 1999... Thomas Jefferson University (Philadelphia, PA) has patented conjugated compounds which comprise an ST receptor binding moiety and a radiostable active moiety, and methods of treating an individual suspected of suffering from metastasized...
Yissum applies for patent.(Brief Article)
December 1, 1999... Yissum Research & Development Company (Israel) has applied for a patent covering a method for stimulating or modulating an immune response to an antigenic molecule in a mammalian subject, comprising administering the antigenic molecule...
Inex applies for patent.(Brief Article)
December 1, 1999... Inex Pharmaceuticals Corporation has applied for a patent covering a method for sensitizing cells to compounds using lipid-mediated gene and compound delivery, used in, e.g. tumor treatment. (US Appl. 243102; WO Publication 9939740)
Human Genome Sciences applies for patent.
December 1, 1999... Human Genome Sciences, Inc. (Rockville, MD) has applied for a patent covering isolated human serine protease and serpin polypeptides, used to develop products for treating immune disorders, cancers, inflammation, transplant rejection or...
Zymogenetics applies for patent.(Brief Article)
December 1, 1999... Zymogenetics, Inc. (Seattle, WA) has applied for a patent covering human angiopoietin homologue, ZAPO3 useful for study and regulation of angiogenesis. (US Appl. 18258; WO Publication 9940193)
University of Alabama at Birmingham applies for patent.(Brief Article)
December 1, 1999... University of Alabama at Birmingham (Birmingham, AL) has applied for a patent covering the use of HIV-1 integrase mutants and fusion proteins to assess the effectiveness of HIV-1 drug candidates. (US Appl. 74274; WO Publication 9940227)
Thomas Jefferson University applies for patent.(Brief Article)
December 1, 1999... Thomas Jefferson University (Philadelphia, PA) has applied for a patent covering hapten-modified tumor cell membranes used for treatment of malignancies and tumors and for stimulation of T cells. (US Appl. 25012; WO Publication 9940925)
Genetics Institute applies for patent.(Brief Article)
December 1, 1999... Genetics Institute, Inc. (Cambridge, MA) has applied for a patent covering vaccines having interleukin-12 and Herpes simplex viral antigen used to modulate the protective immune response to the antigen. (US Appl. 74503; WO Publication 9940938)...
Cadus applies for patent.(Brief Article)
December 1, 1999... Cadus Pharmaceuticals Corporation (Tarrytown, NY) has applied for a patent covering mammalian serine-threonine protein kinase for treating disorder characterized by aberration of the enzyme gene.. (US Appl. 23130; WO Publication 9941385)
GenVec applies for patent.(Brief Article)
December 1, 1999... GenVec, Inc. (Rockville, MD) has applied for a patent covering a method for propagating a viral eukaryotic gene transfer vector derived from a deleterious virus or comprising a deleterious gene in eukaryotic cells in vitro. (US Appl. 74372; WO...
University of Texas applies for patent.(Brief Article)
December 1, 1999... University of Texas (Austin, TX) has applied for a patent covering a method for inhibiting cancer cell growth or killing cancer cells which comprises administering phosphatidylserine or polypeptide conjugate to elicit an immune response. (US...
Brigham & Women's Hospital applies for patent.(Brief Article)
December 1, 1999... Brigham &
Women's Hospital (Boston, MA) has applied for a patent covering a method for determining the likelihood of a human to develop an autoimmune disease by determining the number of CD4-CD8- Valpha24JalphaQ+ T cells. (US Appl. 70298;...
University of Toronto applies for patent.
December 1, 1999... University of Toronto (Toronto, Canada) has applied for a patent covering a method for identifying substances that alter presenilin interactions, useful for screening individuals for presenilin alleles associated with Alzheimer's disease, and...
Creative Biomolecules applies for patent.(Brief Article)
December 1, 1999... Creative Biomolecules, Inc. (Hopkinton, MA) has applied for a patent covering a method for protecting cognitive function using morpohogenic proteins. (US Appl. 12846; WO Publication 9937320)
Osaka Bioscience Institute applies for patent.(Brief Article)
December 1, 1999... Osaka Bioscience Institute (Osaka, Japan) has applied for a patent covering anti-Fas ligand antibody useful in treatment and prevention of AIDS. (US Appl. 999631; WO Publication 9937328)
Regeneron applies for patent.(Brief Article)
December 1, 1999... Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) has applied for a patent covering an orphan receptor of the human cytokine receptor family, designated ORC1, useful for diagnosing and treating endocrine disorders. (US Appl. 12072; WO...