The Brown University Child and Adolescent Psychopharmacology Update articles from May 2009

The Brown University Child and Adolescent Psychopharmacology Update archives from May 2009

ADHD medications and cardiovascular safety: the ECG revisited.(Adverse Events)
May 1, 2009... In a new review of medications for attention-deficit/hyperactivity disorder (ADHD) and cardiovascular safety, authors Jeffrey H. Newcorn, M.D., and Craig Donnelly, M.D., present an overview for clinicians on ADHD drug treatment in children and...

Fluoxetine does not outperform placebo for comorbid depression, substance use.(Comorbidity)
May 1, 2009... A new study published in Child and Adolescent Psychiatry and Mental Health led to the unexpected finding that while the antidepressant fluoxetine was effective for many adolescents with depression and co-occurring alcohol and marijuana use, so...

Current consensus recommendations.(Comorbidity)(Report)
May 1, 2009... * Since certain heart conditions in children may be difficult (or, in some cases, impossible) to detect, consensus recommendations call for a careful assessment for heart conditions in children being considered for ADHD drug treatment, by...

Divalproex ER and placebo equal in bipolar youth.(What's New In Research)(Clinical report)
May 1, 2009... There is no evidence supporting divalproex extended-release (ER) treatment in youths with bipolar I disorder, according to investigators of a 28-week randomized, placebo-controlled trial with 6-month open extension. During the double-blind...

ADHD treatment discontinuation in the UK.(What's New In Research)(Clinical report)
May 1, 2009... A longitudinal study carried out in the United Kingdom (UK) found a significant reduction in drug prescriptions for attention-deficit/hyperactivity disorder (ADHD) associated with increasing age in patients 15 to 21 years. The reduction was...

Ibuprofen for nocturnal enuresis.(What's New In Research)
May 1, 2009... Ibuprofen was superior to placebo in reducing nighttime urinary incontinence in children 6 to 11 years of age. Adding pseudoephedrine to ibuprofen did not enhance or diminish ibuprofen's efficacy. The findings are from a 2-week, randomized,...

Intramuscular ziprasidone for severe agitation.(News Notes)
May 1, 2009... Adolescents with severe agitation received comparable benefits from treatment with intramuscular (IM) ziprasidone as well as with haloperidol IM combined with lorazapam IM. The finding is from a naturalistic, retrospective observational study...

Quetiapine for teen bipolar disorder.(News Notes)
May 1, 2009... Findings from a 48-week study suggest that quetiapine monotherapy is generally well tolerated and effective as maintenance treatment in some adolescent bipolar patients. Thirteen of 18 participants who completed the trial were maintained...

Behavioral improvements in ADHD with once-daily atomoxetine.(News Notes)
May 1, 2009... Atomoxetine taken once daily in the morning, improved morning and evening behavior in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). In 2 open-label studies carried out in Germany, 421 ADHD patients, ages 6 to 17...

ECT successful for treating severe self-injury in autistic boy.(Case Report)
May 1, 2009... Patient: Male, 8 years old Interventions: Sertraline (Zoloft), fluoxetine (Prozac), clomipramine (Anafranil), valproic acid (Depakene), lithium carbonate (Eskalith), carbamazepine (Tegretol), oxcarbazepine (Trileptal), gabapentin (Neurontin),...

[check] new approvals.(From the FDA)
May 1, 2009... First-time generic versions of Topamax (topiramate) have been approved to prevent seizures. Prescribing information for the generic will vary from Topamax as some uses continue to be protected by patents and exclusivity....

Ziprasidone (generic), ziprasidone hydrochloride (HCl), ziprasidone mesylate (brand: Geodon).
May 1, 2009... What is ziprasidone? Ziprasidone is in a class of medications called atypical antipsychotics. Ziprasidone is used for the treatment of schizophrenia, with injectable ziprasidone (intramuscular) indicated for the rapid treatment of acute...