Phytomedicine: International Journal of Phytotherapy & Phytopharmacology articles from June 2008

Phytomedicine: International Journal of Phytotherapy & Phytopharmacology archives from June 2008

Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled study.(Clinical report)
June 1, 2008... Abstract Objectives: The aim of this study was to evaluate the efficacy of the natural antioxidant astaxanthin in functional dyspepsia in different doses and compared with placebo. Design: The study was a controlled, prospective,...

Boswellic acids: a leukotriene inhibitor also effective through topical application in inflammatory disorders.
June 1, 2008... Abstract Boswellic acids (BA), a natural mixture isolated from oleo gum resin of Boswellia serrata comprised of four major pentacyclic triterpene acids: [beta]-boswellic acid (the most abundant), 3-acteyl-[beta]-boswellic acid,...

The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
June 1, 2008... Abstract Aim of the study is to evaluate the anti-ulcer efficacy of the boswellic acids (BA), a triterpenoid known as anti-inflammatory/anti-arthritic agent, which is in clinical use. The reason for the study is that, the known...

Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula.(Report)
June 1, 2008... Abstract The anti-inflammatory and anti-nociceptive effects and the molecular mechanisms of JCICM-6 purified extract derived from an anti-arthritic Chinese herbal formula composed of Caulis Sinomenii, Aconiti laterralis Preparata, Rhizoma...

Antinociceptive activity of petroleum ether fraction from the MeOH extracts of Paederia scandens in mice.(Report)
June 1, 2008... Abstract The petroleum ether fraction of MeOH extract from Paederia scandens was evaluated on anti-nociceptive activity in mice using chemical and thermal models of nociception. Given orally, the petroleum ether fraction (PEF) at doses of...

Effect of seabuckthorn leaf extracts on circulating energy fuels, lipid peroxidation and antioxidant parameters in rats during exposure to cold, hypoxia and restraint (C-H-R) stress and post stress recovery.
June 1, 2008... Abstract The present study was carried out to study mechanism of adaptogenic activity of seabuckthorn leaf extract, administered orally in rats both in single and five doses at a dose of 100mg/kg body weight 30 min prior to C-H-R exposure....

Effects of carvacrol on defects of ischemia-reperfusion in the rat liver.
June 1, 2008... Abstract Many plants found in nature have been used to treat various illnesses. One such plant is oregano (Kekik in Turkish). Health beneficial effects of carvacrol obtained from oregano oil have been shown scientifically. We have...

Changes in antioxidant defense status in hypercholesterolemic rats treated with Ajuga iva.
June 1, 2008... Abstract The aim of the study was to investigate the effect of aqueous extract of Ajuga iva (Ai) on serum and tissues lipid peroxidation as well as antioxidant enzymes activities in red blood cells (RBC) and tissues, in high...

Hepatoprotective potential of Fumaria indica Pugsley whole plant extracts, fractions and an isolated alkaloid protopine.
June 1, 2008... Abstract The present investigation demonstrates the hepatoprotective potential of 50% ethanolic water extract of whole plant of Fumaria indica and its three fractions viz., hexane, chloroform and butanol against D-galactosamine induced...

The antidepressant-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice.
June 1, 2008... Abstract The aim of the present work is to evaluate the putative antidepressant-like effects of a hydro-ethanolic extract (CEAp) and their fractions from the aerial parts of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) on the...

Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa.
June 1, 2008... Abstract We have previously evaluated the neuroprotective effect of catalpol on aging mice induced by D-galactose, in which catalpol treatment ameliorated cognition deficits and attenuated oxidative damage in mice brain. To thoroughly...

The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats.(Report)
June 1, 2008... Abstract In this study, the aphrodisiac activities of Crocus sativus stigma aqueous extract and its constituents, safranal and crocin, were evaluated in male rats. The aqueous extract (80, 160 and 320 mg/kg body wt.), crocin (100, 200 and...

Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin.
June 1, 2008... Abstract Apocynin (4-hydroxy-3-methoxyacetophenone) is a major active ingredient from the rhizomes of Picrorhiza kurroa, a botanical plant used as an herbal medicine for treatment of a number of inflammatory diseases. Recently, apocynin is...

Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells.
June 1, 2008... Abstract The purpose of this report is to explore the growth inhibitory effect of extracts and compounds from black cohosh and related Cimicifuga species on human breast cancer cells and to determine the nature of the active components....

In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes.
June 1, 2008... Abstract Lentinula edodes, known as "shiitake" is one of the widely used medicinal mushroom in the Orient. Antitumour activity of extracts of this mushroom has been widely demonstrated in animals and humans. However, this activity was...

Guatemalan plants extracts as virucides against HIV-1 infection.(human immunodeficiency virus)
June 1, 2008... Abstract Prevention methods to avoid transmission of pathogens, including HIV, are crucial in the control of infectious diseases, not only to block epidemic spread but to avoid long-term treatments leading to emergence of resistances and...

Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis).
June 1, 2008... Abstract Rhabdomyolysis is a potentially life-threatening disorder that occurs as a primary disease or as a complication of a broad spectrum of other diseases. We report the first case of acute rhabdomyolysis after ingestion of Spirulina...

Antiproliferative activity of Pterodon pubescens Benth. seed oil and its active principle on human melanoma cells.(SHORT COMMUNICATION)
June 1, 2008... Abstract On a preliminary screening, relevant in vitro antiproliferative activity was observed to the crude ethanolic extract of Pterodon pubescens seed oil against the human melanoma cell line SK MEL 37. The diethyl ether fraction from...

Antimalarial activity of anthothecol derived from Khaya anthotheca (Meliaceae).(SHORT COMMUNICATION)
June 1, 2008... Abstract Antimalarial activity of anthothecol, a limonoid of Khaya anthotheca (Meliaceae) against Plasmodium falciparum was tested using a [[.sup.3] H]-hypoxanthine and 48 h culture assay in vitro. Anthotechol showed potent antimalarial...

Impact of herbal medicines on physical impairment.
June 1, 2008... Abstract The usefulness of recording physical impairment during intervention studies in chronic low back patients has been questioned. A re-analysis of all of our studies investigating aqueous extracts of Harpagophytum procumbens and a...

Boswellia serrata (Frankincense) - from traditional Indian medicine (Ayurveda) to evidence-based medicine.
June 1, 2008... Boswellia Symposium in honour of the 75th birthday of Professor Dr. H.P.T. Ammon, Emeritus Department of Pharmacology, Pharmaceutical Institute of the Eberhard-Karls University of Tubingen (Germany) For thousands of years, frankincense has...

Medical use of incense (Olibanum) in different historical periods.
June 1, 2008... Incense has been used in various cultures for thousands of years for medical purposes. In these times, it was not possible to the physician to ascertain an exact diagnosis. Medical treatment of patients happened due to visible symptoms, claimed...

Salai guggal and boswellic acids: their effects on the arachidonic acid cascade.
June 1, 2008... Salai guggal is the gum resin from the tree Boswellia serrata. Based on studies by G.B. Singh and C.K. Atal showing anti-inflammatory activity of extracts, we studied the effect of an extract of B. serrata and a variety of boswellic acids on...

Topical use of frankincense.(Brief article)
June 1, 2008... The idea of topical use of frankincense has a long history. The use of pastes, bandages and patches containing frankincense has already been mentioned in several sources of ancient world. Efforts in developing chemical drugs and associated...

Efficacy and safety of Boswellia serrata extract H15.
June 1, 2008... Our study therapy of active Crohn's disease with Boswellia serrata extract H15 [Z. Gastrenterol. 2001; 39: 11-17] aimed at comparing the efficacy and safety of H15 with mesalazine. As primary outcome, changes of the CDAI values between the...

Chemistry and incense.(Brief article)
June 1, 2008... We became interested in incense and boswellic acids in 1996 through an article in "Schwabisches Tagblatt" where the research of Prof. Ammon was highlighted. At that time, I started independent scientific work at TU Munchen in the field of...

Boswellia serrata extract for the treatment of collagenous colitis a double-blind randomized, placebo-controlled, multicenter trial.
June 1, 2008... Int J Colorectal Dis., 2007 Dec; 22(12), 1445-1451. Epub 2007 Sep 2. Background & Aims: To investigate the effect of Boswellia serrata extract (BSE) on symptoms, quality of life and histology in patients with collagenous colitis. ...

Boswellia preparations: current market situation and clinical trials.(Brief article)
June 1, 2008... The anti-inflammatory properties of frankincense, the gum resin derived from Boswellia species, are well-recognized, and frankincense extracts are frequently and increasingly used in folk medicine to cure chronic inflammatory diseases all over...

Development steps of the herbal medicinal product Boswelan[C] for maintaining remission of Crohn's disease.(Clinical report)
June 1, 2008... Boswellia serrata gum resin was formulated into soft gelatine capsules as semifluid mass from its ethanol extract mixed with a polyethylene as inert carrier. The scientific advice by the competent Higher Federal Authority in Germany (BfArM)...

Pharmacological profile of boswellic acids obtained from Boswellia serrata as a new type of non-steroidal anti-in-flammatory drug.
June 1, 2008... Over last three decades, we have been actively engaged in research and development of safe and effective anti-inflammatory drugs particularly from natural sources (Singh et al., 1986, 1993, 1994a, b, 1996a-c) with selective inhibitory action on...

Systemic availability of boswellic acids following oral administration.
June 1, 2008... In vitro studies revealed, that boswellic acids (BAs), the active ingredients of Boswellia serrata extract, may represent promising alternative/adjuvant agents for the treatment of inflammatory diseases and cerebral oedema. 11-Keto-[beta]...

Boswellia and the complement system: A multiherbal drug for multitarget therapy.
June 1, 2008... Because a pathologically prolonged and sustained activation of the complement system is implicated in a variety of inflammatory disorders, from rheumatoid arthritis and glomerulonephritis to systemic lupus erythematodes, we have investigated...

Identification of targets and molecular modes of action of boswellic acids.
June 1, 2008... The anti-inflammatory properties of frankincense, the gum resin derived from Boswellia species, are generally well-recognized, and frankincense extracts are frequently and increasingly used in folk medicine to cure chronic inflammatory...

Effects of boswellic acids on malignant glioma.(Brief article)
June 1, 2008... Conventional malignant glioma therapy regarding to surgery, radiation therapy and chemotherapy is not satisfying. The prognosis of the glioma patient depends more on the histological grading of the tumor and patients age than on the therapy....