Phytomedicine: International Journal of Phytotherapy & Phytopharmacology articles from January 2005

Phytomedicine: International Journal of Phytotherapy & Phytopharmacology archives from January 2005

A 1-year follow-up after a pilot study with Doloteffin[R] for low back pain.
January 1, 2005... Abstract Objective: To complete a year's follow-up on patients from a 6-week double-blind pilot comparison between 44 Doloteffin[R] patients and 44 rofecoxib patients being treated for acute exacerbations of chronic low back pain. ...

Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: considerations on possible bleeding complications after oral intake of Ginkgo biloba extracts.
January 1, 2005... Abstract The special Ginkgo biloba leaf extract EGb 761[R] is marketed for more then two decades. During this time its therapeutic efficacy and favorable safety profile have been proven in numerous clinical trails as well as by...

Low-dose Tadenan protects the rabbit bladder from bilateral ischemia/reperfusion-induced contractile dysfunction.
January 1, 2005... Abstract Recent studies indicate that focal ischemia/reperfusion (I/R) can cause the contractile dysfunctions induced in animal models of partial bladder outlet obstruction. Tadenan (Pygeum africanum) pretreatment can prevent the rabbit...

Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis.
January 1, 2005... Abstract Oral mucositis is a known complication of methotrexate (MTX) therapy, but a single efficacious intervention or agent for prophylaxis or management of this side effect has not yet been identified. We report a case of MTX-induced...

Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.
January 1, 2005... Abstract Extracts from artichoke leaves are traditionally used in the treatment of dyspeptic and hepatic disorders. Various potential pharmacodynamic effects have been observed in vitro for mono- and dicaffeoylquinic acids (e.g....

Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination.
January 1, 2005... Abstract Kava kava extract, Passiflora extract and a combination of both extracts, administered to mice, caused a significant decrease of the amphetamine-induced hypermotility and significant prolongation of sleeping phase induced by...

A new approach to pharmacological effects on ciliary beat frequency in cell cultures--exemplary measurements under Pelargonium sidoides extract (EPs 7630).
January 1, 2005... Abstract The ciliary beat frequency (CBF) is an important parameter of the defence mechanism of the mucociliary system. We present a new method to determine pharmacological effects on CBF in vitro. Ciliated cell cultures of human nasal...

Troxerutin protects the isolated perfused rat liver from a possible lipid peroxidation by coumarin.
January 1, 2005... Abstract For more than 40 years coumarin has been successfully used in the therapy of chronic venous insufficiency (CVI). The occurrence of liver injuries is rather rare and happens predominantly when doses are administered which are...

Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats.
January 1, 2005... Abstract The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- and paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by...

The secretagogue effect of the poison from Centruroides limpidus limpidus on the pancreas of mice and the antagonistic action of the Bouvardia ternifolia extract.
January 1, 2005... Abstract In Mexican traditional medicine the plant species Bouvardia ternifolia is used as remedy to treat patients who have been stung by scorpions. In the preceding study, the methanol extract from the roots of this plant was capable of...

Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz Bip.
January 1, 2005... Abstract The leaves of Mikania (Asteraceae) species are used in folk medicine as antispasmodic, antiulcerogenic and antirheumatic agents. Phytochemical screening of the crude hydroalcoholic 70% extract (CHE) of Mikania laevigata Shultz...

Antinociceptive effect of Nidularium procerum: a Bromeliaceae from the Brazilian coastal rain forest.
January 1, 2005... Abstract Nidularium procerum, a common plant of the Brazilian flora, has not yet been studied for its pharmacological properties. We report here that extracts of N. procerum show both analgesic and anti-inflammatory properties. Oral (p.o.)...

Platelet-activating factor (PAF) receptor-binding antagonist activity of Malaysian medicinal plants.
January 1, 2005... Abstract Forty-nine methanol extracts of 37 species of Malaysian medicinal plants were investigated for their inhibitory effects on platelet-activating factor (PAF) binding to rabbit platelets, using [.sup.3]H-PAF as a ligand. Among them,...

Herbal remedies improve the strength of repairing ligament in a rat model.
January 1, 2005... Abstract Herbal remedies have been reported to be effective in controlling inflammation for acute soft tissue injuries. There exist, however, no reports of their effects on collagen production and remodeling; thus mechanical strength...

In vitro decreases of the fibrinolytic potential of cultured human fibrosarcoma cell line, HT1080, by Nigella sativa oil.
January 1, 2005... Abstract It is generally accepted that the fibrinolytic potential of tumor cells is related to their malignant phenotype. In the present study, Nigella sativa oil (NSO) was studied to evaluate its effect on the fibrinolytic potential of...

1,3-dihydroxy-5-(tridec-4',7'-dienyl)benzene: a new cytotoxic compound from Lithraea molleoides.
January 1, 2005... Abstract A dichloromethane extract from the leaves of Lithraea molleoides (Anacardiaceae), an argentine medicinal plant, showed cytotoxicity on human hepatocellular carcinoma cell line. Bioassay guided fractionation of this extract led to...

Screening for antiproliferative activity of six southern Brazilian species of Hypericum.
January 1, 2005... Abstract The crude methanolic extracts of six species of Hypericum growing in southern Brazil (Hypericum caprifoliatum Cham. & Schlecht., H. carinatum Griseb., H. connatum Lam., H. myrianthum Cham. & Schlecht., H. polyanthemum Klotzsch ex...

Antitoxin activity of plants used in Mexican traditional medicine against scorpion poisoning.
January 1, 2005... Abstract Scorpions, especially in urban areas of tropical and subtropical regions, present a common risk of poisoning. In Mexico, scorpion envenomation is considered a public health problem. Despite the frequency of scorpion sting cases,...

Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two major myotoxins, BthTX-I and BthTX-II, by the aqueous extract of Tabernaemontana catharinensis A. DC. (Apocynaceae).
January 1, 2005... Abstract Partial neutralization of the myotoxic effect of Bothrops jararacussu venom (BV) and two of its myotoxins [bothropstoxin-I (BthTX-I), catalytically inactive, and II (BthTX-II), showing low PL[A.sub.2] activity], by the lyophilized...

Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts.
January 1, 2005... Abstract Lycium barbarum L. (Solanaceae) glycoconjugates (LbGp) display an interesting array of anti-apoptotic and antioxidant properties, which may be beneficial for human skin. We therefore set out to determine the effects of LbGp in...

Antiinflammatory and chronic toxicity study of the leaves of ageratum conyzoides L. in rats.(SHORT COMMUNICATION)
January 1, 2005... Abstract The hydroalcoholic extract (HAE) of Ageratum conyzoides leaves was studied for its antiinflammatory effect on subacute (cotton pellet-induced granuloma) and chronic (formaldehyde-induced arthritis) models of inflammation in rats....

Assessment of estrogenic activity of flavonoids from Mediterranean plants using an in vitro short-term test.(SHORT COMMUNICATION)
January 1, 2005... Abstract Six isoflavones, daidzein (4',7,-dihydroxyisoflavone), genistein (4',5,7-trihydroxyisoflavone), genistin (genistein 7-O-[beta]-D-glucopyranoside), isoprunetin (4',7-dihydroxy, 5-metoxyisoflavone), isoprunetin...

Large-scale observational studies of hypericum extracts in patients with depressive disorders--a systematic review.
January 1, 2005... Abstract We present a systematic review of observational studies of hypericum extracts in the treatment of depressive disorders. We included non-randomized studies with at least 100 patients suffering from depressive disorders treated with...

Medicinal and aromatic plants--industrial profiles, Vol. 19: Stevia.(Book Review)
January 1, 2005... Medicinal and aromatic plants--industrial profiles, Vol. 19: Stevia D.A. Kinghorn (Ed.); Taylor & Francis Inc., London, 2002, 211 p., price $90.00, ISBN 0-415-26830-3 Volume 19 of the series Medicinal and aromatic plants--industrial...

Lavender: the genus Lavandula (1st Edition).(Book Review)
January 1, 2005... Lavender: The Genus Lavandula (1st Edition) Lis-Balchin, M. (Ed.); Taylor & Francis, London, 2002, 292p., price $128.00, ISBN 0415284864 (HC) With the publication of Lavender: the genus Lavandula, the Harwood Academic Publishers and...

Recent Progress in Medicinal Plants, Vol. 5--Crop Improvement, Production Technology, Trade and Commerce (1st Edition).(Book Review)
January 1, 2005... Recent progress in medicinal plants, Vol. 5--crop improvement, production technology, trade and commerce (1st Edition) J.N. Govil, J. Pandey, B.G. Shivakumar, and V.K. Singh (Eds.); SCI Tech Publishing LLC, Houston, USA, 2002, (xxviii +...

Recent Progress in Medicinal Plants, Vol. I: Ethnomedicine and Pharmacognosy.(Book Review)
January 1, 2005... Recent progress in medicinal plants, Vol. I: Ethnomedicine and Pharmacognosy V.K. Singh, J.N. Govil, and G. Singh (Eds.); Sci Tech Publishing LLC, Houston, TX, 2002, 399p, price $80.00, ISBN 0-9656038-6-5 Two ancient herbal healing...

Biology of marijuana: from gene to behaviour, 1st Edition.(Book Review)
January 1, 2005... Biology of marijuana: from gene to behaviour, 1st Edition E.S. Onaivi (Ed); Taylor & Francis, London, 2002, 635 p., price $150.00, ISBN 0-415-27348-X (HC) There is tremendous activity in the world of cannabis research at present. A...