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Randomized trial of a fixed combination (KanJang[R]) of herbal extracts containing Adhatoda vasica, Echinacea purpurea and Eleutherococcus senticosus in patients with upper respiratory tract infections.
August 1, 2005... Abstract
The clinical efficacy of KanJang[R] oral solution, a fixed combination of standardised extracts of Echinacea purpurea, Adhatoda vasica and Eleutherococcus senticosus, was compared with the combined extracts of Echinacea purpurea...
A randomized double blind placebo-controlled clinical trial of Hochuekkito, a traditional herbal medicine, in the treatment of elderly patients with weakness N of one and responder restricted design.
August 1, 2005... Abstract
Objective: To evaluate the effects of Hochuekkito, a traditional Japanese and Chinese medicine, in the treatment of elderly patients with general weakness. To devise a suitable study design for assessing the clinical effectiveness...
Effect of Cassia auriculata Linn. Root extract on cisplatin and gentamicin-induced renal injury.
August 1, 2005... Abstract
The ethanol extract of the roots of Cassia auriculata was studied for its nephroprotective activity in cisplatin- and gentamicin-induced renal injury in male albino rats. In the cisplatin model, the extract at doses of 300 and 600...
Actions of Ya-hom, a herbal drug combination, on isolated rat aortic ring and atrial contractions.
August 1, 2005... Abstract
The effect of the Thai popular medicine Ya-hom on cardiovascular function was studied in isolated rat aortic ring and atrium by comparison with norepinephrine (NE). Water extraction of Ya-hom at concentrations of 0.83, 1.67, 8.33...
Evaluation of the effect of aqueous extract of Croton urucurana Baillon (Euphorbiaceae) on the hemorrhagic activity induced by the venom of Bothrops jararaca, using new techniques to quantify hemorrhagic activity in rat skin.
August 1, 2005... Abstract
Aqueous extracts of Croton urucurana (Sangra D'agua), a plant popularly considered a cicatrizant, were analyzed for anti-Bothrops jararaca venom activity. The plant extracts antagonized the hemorrhagic activity of the venom and...
Oral administration of paclitaxel affects the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats.
August 1, 2005... Abstract
To evaluate the question of whether or not paclitaxel affects the distribution and metabolism of chemical carcinogens such as 2-aminofluorene (AF) on Sprague-Dawley rats were examined. The AF, acetylated AF and AF metabolites were...
Dandelion (Taraxacum officinale) flower extract suppresses both reactive oxygen species and nitric oxide and prevents lipid oxidation in vitro.
August 1, 2005... Abstract
Flavonoids and coumaric acid derivatives were identified from dandelion flower (Taraxacum officinale). Characteristics of chain-breaking antioxidants, such as extended lag phase and reduced propagation rate, were observed in...
Treatment effects of EGb 761[R] and cholinesterase inhibitors--why available studies do not demonstrate superiority of the latter.(SHORT COMMUNICATION)
August 1, 2005... Abstract
Based on simple comparisons of drug-placebo differences found in clinical trials, it has repeatedly been concluded that EGb 761[R] is less effective in the treatment of Alzheimer's disease than cholinesterase (ChE) inhibitors....
Peppermint oil in irritable bowel syndrome.
August 1, 2005... Abstract
In a literature search 16 clinical trials investigating 180-200 mg enteric-coated peppermint oil (PO) in irritable bowel syndrome (IBS) or recurrent abdominal pain in children (1 study) with 651 patients enrolled were identified....
Gastrointestinal clinical pharmacology of peppermint oil.
August 1, 2005... Abstract
In nine studies, 269 healthy subjects or patients underwent exposure to peppermint oil (PO) either by topical intraluminal (stomach or colon) or oral administration by single doses or 2 weeks treatment (n = 19). Methods used to...
Pharmacology and preclinical pharmacokinetics of peppermint oil.
August 1, 2005... Abstract
The principal pharmacodynamic effect of peppermint oil relevant to the gastrointestinal tract is a dose-related antispasmodic effect on the smooth musculature due to the interference of menthol with the movement of calcium across...