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Comparison of outcome measures during treatment with the proprietary Harpagophytum extract Doloteffin[R] in patients with pain in the lower back, knee or hip.
April 1, 2002... Summary
Besides checking estimates of effectiveness and safety of using the proprietary Harpagophytum extract Doloteffin[R], this postmarketing surveillance compared various disease-speciffic * and generic ** measures of effect.
We...
Effect of Seihai-to, a Kampo medicine, in relapsing aspiration pneumonia--an open-label pilot study.
April 1, 2002... Summary
Two published case reports described palliation of disease after Seihai-to therapy for refractory aspiration pneumonia caused by recurrent laryngeal nerve paralysis and cerebrovascular disease. We undertook an open-label trial in...
Studies on the psychopharmacological activities of Rumex nepalensis Spreng. root extract in rats and mice.
April 1, 2002... Summary
The methanol extract of Rumex nepalensis Spreng. (Family -- Polygonaceae) was assessed for different psychopharmacological activities in rats and mice by evaluation of general behaviour, exploratory behaviour, muscle relaxant...
Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats.
April 1, 2002... Summary
Bacopa monniera Wettst. (syn. Herpestis monniera L.; Scrophulariaceae) is a commonly used Ayurvedic drug for mental disorders. The standardized extract was reported earlier to have significant anti-oxidant effect, anxiolytic...
Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole-and maximal electroshock-induced seizures.
April 1, 2002... Summary
The leaf essential oil of Laurus nobilis Linn., Lauraceae, which has been used as an antiepileptic remedy in Iranian traditional medicine, was evaluated for anticonvulsant activity against experimental seizures. The essential oil...
Anticonvulsant activity of aqueous extract of Leonotis leonurus.
April 1, 2002... Summary
Water extract of Leonotis leonurus was tested for anticonvulsant activity against seizures produced in mice by pentylenetetrazole, picrotoxin, bicuculline and N-methyl-DL-aspartic acid (intraperitoneal injections). L. leonurus...
Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics.
April 1, 2002... Summary
Piperine (1-Piperoyl piperidine) is a major alkaloid of Piper nigrum Linn. and Piper longum Linn. It is shown to possess bioavailability-enhancing activity with various structurally and therapeutically diverse drugs. The mechanism...
Protective effect of green tea against lipid peroxidation in the rat liver, blood serum and the brain. (*).
April 1, 2002... Summary
This paper reports data on the effect of green tea on the lipid peroxidation products formation and parameters of antioxidative system of the liver, blood serum and central nervous tissue of healthy young rats drinking green tea...
Free radical scavenging action of the medicinal herb Limonium wrightii from the Okinawa Islands.
April 1, 2002... Summary
Free radical scavenging action of Limonium wrightii O. kunthe was examined in vitro and in vivo by using electron spin resonance spectrometer and chemiluminescence analyzer. A water extract of L. wrightii showed a strong scavenging...
The anti-Inflammatory and analgesic effects of a crude extract of Petiveria alliacea L. (phytolaccaceae).
April 1, 2002... Summary
Petiveria alliacea L (Phytolaccaceae) is a perennial bush plant that grows widely in Brazil. The roots and leaves of P. alliacea have been used in folk medicine for their antispasmodic, sedative, diuretic and antihelminthic...
Bioactivity of alkamides isolated from Echinacea purpurea (L.) Moench.
April 1, 2002... Summary
Alkamides from the roots of Echinacea purpurea (L.) Moench were examined for anti-inflammatory activity in an in vitro model system. Cyclooxygenase-I (COX-I) and cyclooxygenase-II (COX-II) inhibitory activities were assessed at pH...
Ginseng berry reduces blood glucose and body weight in db/db mice.
April 1, 2002... Summary
In this study, we observed anti-diabetic and anti-obesity effects of Panax ginseng berry in adult C57BL/Ks db/db mice and their lean littermates. Animals received daily intraperitoneal injections of Panax ginseng berry extract at...
Formulation of an effective mosquito-repellent topical product from Lemongrass oil.
April 1, 2002... Summary
Ointment and cream formulations of lemongrass oil in different classes of base and the oil in liquid paraffin solution have been evaluated for mosquito repellency in a topical application. Mosquito repellency was tested by...
Effects of intrinsic fluorescence and quenching on fluorescence-based screening of natural products.
April 1, 2002... Summary
To evaluate the effects of intrinsic (natural) fluorescence and quenching as confounding variables in fluorescence-based enzyme inhibition assays of natural products, we measured the fluorescence and quenching properties of 25...
The Chemical Synthesis of Natural Products. (Book Review).
April 1, 2002... Hale, K. J. (Ed.); The Chemical Synthesis of Natural Products
1st edition, 429 P. CRC Press, Baton Rouge FL, and Sheffield Academic Press, Sheffield, UK, 2000
Price: $159.95. ISBN 1-84127-039-3 (HC)
Karl J. Hale, University College...
Principles of Biochemical Toxicology. (Book Review).
April 1, 2002... Timbrell, J. (ed.): Principles of Biochemical Toxicology
3rd edition, 394 p. Taylor and Francis Ltd, London 2000.
Price: US $ 65.00
ISBN 07484-07375 (HC)
The seven chapters in this third edition of "Principles of Biochemical...