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The Brown University Geriatric Psychopharmacology Update articles from September 2002
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The Brown University Geriatric Psychopharmacology Update archives from September 2002
Aromatherapy may be safe and effective for management of agitation in severe dementia. (Innovations in Alternative Medicine).
September 1, 2002... More than half of all individuals diagnosed with dementia display what is known as "behavioral and psychological symptoms in dementia" (BPSD). The typical first-line treatment for this problem is pharmacotherapy, specifically neuroleptic...
EVA study finds risk of cognitive decline with long-term benzodiazepine use. (Adverse Events).(Epidemiology of Vascular Aging)
September 1, 2002... The U.S. National Health and Medical Research Council and the U.S. Food and Drug Administration (FDA) recommend that benzodiazepine use not exceed four months duration. However, prolonged benzodiazepine use among the elderly still occurs....
Possible citalopram-acenocoumaraol interaction results in spontaneous bleeding. (Drug-Drug Interactions).(Brief Article)
September 1, 2002... Citalopram (Celexa) is a new selective serotonin reuptake inhibitor (SSRI) that has negligible affinity for adrenergic, dopaminergic, histaminergic and muscarinic cholinergic receptors. This increase in overall selectivity has resulted in a...
News from the 8th International Conference on Alzheimer's disease and related disorders. (Conference Update).(Brief Article)
September 1, 2002... Antiinflammatory drugs not effective for AD
The use of nonsteroidal antiinflammatory drugs has no impact on cognitive or behavioral function in patients with Alzheimer's disease (AD), according to research presented at the 8th International...
Lithium assessed for depression prophylaxis. (Clinical Notes).(Brief Article)
September 1, 2002... Researchers from Southampton, U.K., conducted a double-blind, placebo-control led trial of prophylactic lithium (Eskalith and others)therapy in elderly patients with major depression taking continuation antidepressants. The subjects were...
Citalopram assessed for depression prophylaxis. (Clinical Notes).(Brief Article)
September 1, 2002... A group of researchers from Denmark conducted a trial of citalopram (Celexa) as prophylaxis against relapse in elderly patients with depression. The subjects were out-patients at least 65 years old with major depression (DSM-IV criteria) and a...
Marker of oxidative damage found in MCI. (Clinical Notes).(mild cognitive impairment)(Brief Article)
September 1, 2002... Using gas chromatography-mass spectrometry analysis, a group of researchers measured the levels of isoprostane 8,12-iso-iP[F.sub.2[alpha]]-VI in patients with mild cognitive impairment (MCI). Elevated levels of this biomarker are found in...
SIADH observed with oxcarbazepine. (Case Reports).(syndrome of inappropriate secretion of antidiuretic hormone)(Brief Article)
September 1, 2002... # Patients: 1 male (70 y/o)
Medications: oxcarbazepine (Trileptal), furosemide (Lasix) and lithium (Eskalith and others)
Comments: A 70-year-old man with a history of prostrate hypertrophy and cataract was hospitalized for bipolar...