The Brown University Geriatric Psychopharmacology Update articles from March 2003

The Brown University Geriatric Psychopharmacology Update archives from March 2003

Clinical management of delirium not standardized. (Best Practices).
March 1, 2003... Researchers from the University of Wisconsin's Center of Women's Health and Women's Health Research and Section of Geriatrics recently published the first report assessing physicians' clinical preferences in the management of delirium in...

Donepezil may help in management of comorbid schizophrenia and dementia. (Comorbidity).
March 1, 2003... The treatment of comorbid schizophrenia and dementia has improved insofar as management of the separate conditions is concerned. However, successful management of the concurrent conditions, frequently observed in clinical practice, still...

Selegiline may increase risk of hypertension with dopamine administration. (Drug-Drug Interactions).
March 1, 2003... Two types of monoamine oxidase exist in the human body: monoamine oxidase type A (MAO-A) and type B (MAO-B). The predominant type of monoamine oxidase in the human brain is MAO-B, which mediates the oxidation of various substrates in the brain,...

Transdermal selegiline avoids adverse effects of oral form. (Drug-Drug Interactions).
March 1, 2003... A new transdermal formulation of the monoamine oxidase inhibitor (MAOI) selegiline (Eldepryl) has proven effective in controlling depression without generating the serious side effects of oral MAOIs. The first placebo-controlled trial of...

Venlafaxine and nortriptyline similar in depression. (Clinical Notes).
March 1, 2003... Researchers in Spain conducted a six-month, single-blind trial comparing venlafaxine (Effexor) to nortriptyline (Aventyl, Pamelor) in treating major depression in 68 patients, finding a similar rate of remission with the two drugs. The...

Early brain changes identified in Alzheimer's disease. (News Updates).(Brief Article)
March 1, 2003... A recent paper published in the Proceedings of the National Academy of Sciences describes the determination of regional brain changes in Alzheimer's disease (AD) using high-resolution magnetic resonance microscopy (MRM). The authors of the...

Researchers discover possible depression gene. (News Updates).(Brief Article)
March 1, 2003... Myriad Genetics recently reported the discovery of a new gene, DEP1, which may be a cause of depression. The gene was discovered through genomic analysis of over 400 Utah families, each with multiple cases and early onset of major depression....

Neuroleptic malignant syndrome with olanzapine. (Case Report).
March 1, 2003... # Patients: 1 male (75 y/o) Medications: olanzapine (Zyprexa) and others Comments: A 75-year-old man with a 40-year history of bipolar I disorder presented with an acute mental status change. He had several psychiatric hospitalizations...

Oxcarbazepine (generic)~trileptal (brand). (Your Medication Information).
March 1, 2003... Classification: Anticonvulsant Common Usage: Oxcarbazepine is used for the treatment of partial seizures, a subtype of epilepsy. It may also be useful in the treatment of bipolar mood disorder. Important Side Effects: Most people who...