The Brown University Geriatric Psychopharmacology Update articles from April 2005

The Brown University Geriatric Psychopharmacology Update archives from April 2005

Statins and dementia: Cache County Study helps separate fact from artifact.(Dementia and Alzheimer's Disease)
April 1, 2005... precis * 6% of Cache County Study participants took statins * Authors examined whether statin use prevented dementia * Cross-sectional analysis showed an inverse relationship * Prospective analysis showed no benefit The...

Part 1: research on treating Alzheimer's disease slowly advancing.(AAGP Conference Report)
April 1, 2005... precis * AAGP research on AD treatment generally extended the use of old drugs * Donepezil: effective for severe AD; safe and effective in African Americans * Quetiapine: reduced agitation; did not increase risk of falls *...

Use of sedatives in the elderly on the rise.(Drug-Drug Interactions)
April 1, 2005... The elderly population as a whole consumes a large amount of psychotropic agents, including benzodiazepines, 1 with a propensity to affect both the physical and mental abilities of the patients. (1,2) The relationship between benzodiazepine use...

Late-life depression: citalopram vs. sertraline.(What's New In Research)
April 1, 2005... precis * One-year follow-up trial of citalopram and sertraline in subjects [greater than or equal to]65 years * 138 outpatients with minor or subsyndromal depression * Citalopram 20 mg/day or sertraline 50 mg/day * Both drugs...

Body pain, treatment response in late-life major depression.(What's New In Research)
April 1, 2005... precis * Study considers link between chronic pain and suicidal ideation * 187 subjects, 69-75 years old, with major depression * Treatment with paroxetine and psychotherapy, up to 26 weeks * No significant association found...

Depression and diabetes medication compliance.(What's New In Research)
April 1, 2005... precis * 203 male patients, mean 67 years, with Type 2 diabetes * Oral hypoglycemic therapy, 73% glyburide, 25% metformin * Self-report and pharmacy data indicate inadequate med compliance In a study published in the American...

Prospective memory failure and Alzheimer's.(News Notes)
April 1, 2005... A study published in the January issue of the journal Neuropsychology adds to limited research to date regarding the relationship of prospective memory (the ability to remember to perform an intended action at a particular point in the future)...

Prescription drug use continues to climb.(News Notes)(Brief Article)
April 1, 2005... According to the National Center for Health Statistics, almost half of all Americans take at least one prescription medication, and one in six individuals is taking three or more. The U.S. Department of Health and Human Services' (HHS) annual...

Duloxetine for cognition and pain symptoms in late-life MDD.(News Notes)(Brief Article)
April 1, 2005... In a study funded by Eli Lilly and Co. and published in the American Journal of Geriatric Psychiatry, the efficacy and safety of duloxetine (Cymbalta) was evaluated in the treatment of major depressive disorder (MDD) and associated pain...

Anticholinergic delirium associated with cyclopentolate.(Case Report)(Brief Article)
April 1, 2005... Patient: Male, 72 y/o Medications: Eye drops containing atropine 0.5% and cyclopentolate 1.0% Comment: A 72-year-old man with an otherwise unremarkable medical history presented with a one-month history of progressive alteration of...

Paxil CR stock pulled.(From the FDA)(Brief Article)
April 1, 2005... Citing inadequate manufacturing practices, the FDA and the Department of Justice have seized all remaining stocks of Paxil CR (paroxetine), approved for the treatment of depression and panic disorder. The FDA encourages consumers who use this...

Aripiprazole approved for bipolar I manic and mixed.(From the FDA)(Abilify)(Brief Article)
April 1, 2005... Bristol-Myers Squibb and Otsuka Pharmaceuticals have announced that aripiprazole (Abilify) tablets and oral solution, an antipsychotic indicated for the treatment of schizophrenia, acute mania and mixed episodes associated with bipolar...

Quetiapine (generic): Seroquel (brand).(Your Medication Information)
April 1, 2005... CLASSIFICATION: Atypical antipsychotic. COMMON USAGE: Quetiapine is used for the treatment of schizophrenia; it is also indicated for the short-term treatment of acute manic episodes associated with bipolar I disorder in adults,...